The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
75
|
sequence length |
194
|
structure length |
189
|
Chain Sequence |
SDSKEVPSLPFLRHLLEELDSHEDSLLLFLCHDAAPGCTTVTQALCSLSQQRKLTLAALVEMLYVLQRMDLLKSRFGLSKEGAEQLLGTSFLTRYRKLMVCVGEELDSSELRALRLFACNLNPSLSTALSESSRFVELVLALENVGLVSPSSVSVLADMLRTLRRLDLCQQLVEYEQQEQARYRYCLHH
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| publication title |
Crystal structure of MC159 reveals molecular mechanism of DISC assembly and FLIP inhibition.
pubmed doi rcsb |
| molecule tags |
Viral protein
|
| source organism |
Molluscum contagiosum virus subtype 1
|
| molecule keywords |
Viral CASP8 and FADD-like apoptosis regulator
|
| total genus |
75
|
| structure length |
189
|
| sequence length |
194
|
| ec nomenclature | |
| pdb deposition date | 2005-10-17 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| A | PF01335 | DED | Death effector domain |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Mainly Alpha | Orthogonal Bundle | Death Domain, Fas | Death Domain, Fas | ||
| Mainly Alpha | Orthogonal Bundle | Death Domain, Fas | Death Domain, Fas |
#chains in the Genus database with same CATH superfamily 1NGR A; 2L9M A; 2LWE A; 4IZ5 E; 4NQK A; 4JUP A; 2O71 A; 1ICH A; 4LWD A; 4N1L A; 1E41 A; 2GF5 A; 1DDF A; 4O6X A; 2DO9 A; 2N83 A; 4UZ0 A; 1N3K A; 3EZQ A; 4O9L A; 1PN5 A; 1CY5 A; 2NSN A; 2BBR A; 4M9X A; 4O7Q A; 4IZ7 B; 4RHW E; 2OF5 H; 3J63 A; 1D2Z A; 2DBG A; 2L6A A; 3CRD A; 2NZ7 A; 4D8O A; 2P1H A; 3CL3 A; 2MN4 A; 2A9I A; 2MS7 A; 4E9M A; 4IZA B; 2YVI A; 1WXP A; 4QOB A; 4I16 A; 2M5V A; 2B1W A; 2MPC A; 2DBH A; 1D2Z B; 4A2W A; 2OF5 A; 2D96 A; 3KAT A; 3LQR A; 1E3Y A; 4F44 A; 4ZBW A; 3YGS P; 2HM2 Q; 2MB9 A; 1YGO A; 2F1S A; 3J6J A; 2N1F A; 3EZQ B; 3MOP A; 4F42 A; 1A1W A; 4A2Q A; 2KN6 A; 4M9S A; 4EWI A; 1A1Z A; 2YQF A; 1WH4 A; 2IB1 A; 3MOP K; 1FAD A; 4N1K A; 2N7Z A; 2BBZ A; 1Z6T A; 1DGN A; 2N00 A; 2LWD A; 2N80 A; 4JQW A; 4M9Z A; 3T6P A; 4P4H I; 1C15 A; 2KM6 A; 2LS7 A; 4P4H A; 3YGS C; 4DWN A; 4RHW A; 2YGS A; 3LQQ A; 3QF2 A; 1UCP A; 4N1J A; 1WMG A; 2NAQ A; 2YU0 A; 1CWW A; 2N97 A; 3MOP G; 2G7R A; 2MS8 A; 4O9F A; 2DBF A; 2A5Y B; 4FH0 A; 2VGQ A; 2DBD A; #chains in the Genus database with same CATH topology 1NGR A; 2L9M A; 2LWE A; 4IZ5 E; 4NQK A; 4JUP A; 2XV9 A; 2O71 A; 1ICH A; 2MJM A; 4LWD A; 4N1L A; 1E41 A; 2GF5 A; 1DDF A; 4O6X A; 2DO9 A; 2N83 A; 4UZ0 A; 1N3K A; 3EZQ A; 4O9L A; 1PN5 A; 1CY5 A; 2NSN A; 2BBR A; 4M9X A; 4O7Q A; 4IZ7 B; 4RHW E; 2OF5 H; 3J63 A; 1D2Z A; 2DBG A; 2L6A A; 3CRD A; 2NZ7 A; 4D8O A; 2P1H A; 3CL3 A; 2MN4 A; 2A9I A; 2MS7 A; 4E9M A; 4IZA B; 2YVI A; 1WXP A; 4QOB A; 4I16 A; 2M5V A; 2B1W A; 2MPC A; 2DBH A; 1D2Z B; 4A2W A; 2OF5 A; 2D96 A; 3KAT A; 3LQR A; 1E3Y A; 4F44 A; 4ZBW A; 3YGS P; 2HM2 Q; 2MB9 A; 1YGO A; 2F1S A; 3J6J A; 2N1F A; 3EZQ B; 3MOP A; 4F42 A; 1A1W A; 4A2Q A; 2KN6 A; 4M9S A; 4EWI A; 1A1Z A; 2YQF A; 1WH4 A; 2IB1 A; 3MOP K; 1FAD A; 4N1K A; 2N7Z A; 2BBZ A; 1Z6T A; 1DGN A; 2N00 A; 2LWD A; 2N80 A; 4JQW A; 4M9Z A; 3T6P A; 4P4H I; 1C15 A; 2KM6 A; 2LS7 A; 4P4H A; 3YGS C; 4DWN A; 4RHW A; 2YGS A; 3LQQ A; 3QF2 A; 1UCP A; 4N1J A; 1WMG A; 2NAQ A; 2YU0 A; 1CWW A; 2N97 A; 3MOP G; 2G7R A; 2MS8 A; 4O9F A; 2DBF A; 2A5Y B; 4FH0 A; 2VGQ A; 2DBD A; #chains in the Genus database with same CATH homology 1NGR A; 2L9M A; 2LWE A; 4IZ5 E; 4NQK A; 4JUP A; 2XV9 A; 2O71 A; 1ICH A; 2MJM A; 4LWD A; 4N1L A; 1E41 A; 2GF5 A; 1DDF A; 4O6X A; 2DO9 A; 2N83 A; 4UZ0 A; 1N3K A; 3EZQ A; 4O9L A; 1PN5 A; 1CY5 A; 2NSN A; 2BBR A; 4M9X A; 4O7Q A; 4IZ7 B; 4RHW E; 2OF5 H; 3J63 A; 1D2Z A; 2DBG A; 2L6A A; 3CRD A; 2NZ7 A; 4D8O A; 2P1H A; 3CL3 A; 2MN4 A; 2A9I A; 2MS7 A; 4E9M A; 4IZA B; 2YVI A; 1WXP A; 4QOB A; 4I16 A; 2M5V A; 2B1W A; 2MPC A; 2DBH A; 1D2Z B; 4A2W A; 2OF5 A; 2D96 A; 3KAT A; 3LQR A; 1E3Y A; 4F44 A; 4ZBW A; 3YGS P; 2HM2 Q; 2MB9 A; 1YGO A; 2F1S A; 3J6J A; 2N1F A; 3EZQ B; 3MOP A; 4F42 A; 1A1W A; 4A2Q A; 2KN6 A; 4M9S A; 4EWI A; 1A1Z A; 2YQF A; 1WH4 A; 2IB1 A; 3MOP K; 1FAD A; 4N1K A; 2N7Z A; 2BBZ A; 1Z6T A; 1DGN A; 2N00 A; 2LWD A; 2N80 A; 4JQW A; 4M9Z A; 3T6P A; 4P4H I; 1C15 A; 2KM6 A; 2LS7 A; 4P4H A; 3YGS C; 4DWN A; 4RHW A; 2YGS A; 3LQQ A; 3QF2 A; 1UCP A; 4N1J A; 1WMG A; 2NAQ A; 2YU0 A; 1CWW A; 2N97 A; 3MOP G; 2G7R A; 2MS8 A; 4O9F A; 2DBF A; 2A5Y B; 4FH0 A; 2VGQ A; 2DBD A;
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