2DBFA

Solution structure of the death domain in human nuclear factor nf-kappa-b p105 subunit
Total Genus 21
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
21
sequence length
100
structure length
100
Chain Sequence
GSSGSSGDMKQLAEDVKLQLYKLLEIPDPDKNWATLAQKLGLGILNNAFRLSPAPSKTLMDNYEVSGGTVRELVEALRQMGYTEAIEVIQAASSSGPSSG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structure of the Death domain in human Nuclear factor NF-kappa-B p105 subunit
rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords Nuclear factor NF-kappa-B p105 subunit
total genus 21
structure length 100
sequence length 100
ec nomenclature
pdb deposition date 2005-12-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00531 Death Death domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.533.10 Mainly Alpha Orthogonal Bundle Death Domain, Fas Death Domain, Fas 2dbfA01
4JQWA 4P4HA 2N97A 1N3KA 2DBGA 2DO9A 4RHWA 4IZAB 4P4HI 3MOPK 4A2QA 4N1KA 3YGSC 2NAQA 2N83A 3MOPA 4O6XA 4N1JA 1FADA 3J63A 2BBRA 2OF5H 1UCPA 2MS8A 2DBFA 1ICHA 1D2ZA 2DBHA 2BBZA 2LS7A 1D2ZB 2M5VA 2MB9A 3LQRA 2VGQA 1CWWA 1A1WA 3CL3A 2L6AA 4O9LA 4E9MA 4EWIA 2MPCA 1DGNA 2OF5A 3QF2A 1WMGA 2D96A 2MN4A 3CRDA 2YU0A 4LWDA 4JUPA 1Z6TA 4DWNA 4F42A 2DBDA 2GF5A 1WXPA 1E41A 3MOPG 1CY5A 2N00A 4D8OA 4O7QA 2NZ7A 4M9SA 4NQKA 3T6PA 1NGRA 3J6JA 2KN6A 4RHWE 3LQQA 4ZBWA 2O71A 3EZQB 4I16A 2N80A 2YVIA 4QOBA 1WH4A 4IZ7B 3YGSP 1DDFA 2L9MA 2N7ZA 2KM6A 4UZ0A 1A1ZA 2F1SA 4M9ZA 4M9XA 2A9IA 2LWEA 1C15A 2P1HA 2G7RA 2B1WA 3EZQA 4IZ5E 4N1LA 2MS7A 2LWDA 2YQFA 2YGSA 2A5YB 2N1FA 4A2WA 1E3YA 3KATA 2HM2Q 4FH0A 1YGOA 1PN5A 4F44A 2IB1A 4O9FA 2NSNA
chains in the Genus database with same CATH superfamily
4JQWA 4P4HA 2N97A 1N3KA 2DBGA 2DO9A 4RHWA 4IZAB 4P4HI 3MOPK 4A2QA 2XV9A 4N1KA 3YGSC 2NAQA 2N83A 3MOPA 4O6XA 4N1JA 1FADA 3J63A 2BBRA 2OF5H 1UCPA 2MS8A 2DBFA 1ICHA 1D2ZA 2DBHA 2BBZA 2LS7A 1D2ZB 2M5VA 2MB9A 3LQRA 2VGQA 1CWWA 1A1WA 3CL3A 2L6AA 4O9LA 4E9MA 4EWIA 2MPCA 1DGNA 2OF5A 3QF2A 1WMGA 2D96A 2MN4A 3CRDA 2YU0A 4LWDA 4JUPA 1Z6TA 4DWNA 4F42A 2DBDA 2GF5A 1WXPA 1E41A 3MOPG 1CY5A 2N00A 4D8OA 4O7QA 2NZ7A 4M9SA 4NQKA 3T6PA 1NGRA 3J6JA 2KN6A 4RHWE 3LQQA 4ZBWA 2O71A 3EZQB 4I16A 2N80A 2YVIA 4QOBA 1WH4A 4IZ7B 3YGSP 1DDFA 2L9MA 2N7ZA 2KM6A 4UZ0A 1A1ZA 2F1SA 4M9ZA 4M9XA 2A9IA 2LWEA 1C15A 2P1HA 2G7RA 2B1WA 3EZQA 2MJMA 4IZ5E 4N1LA 2MS7A 2LWDA 2YQFA 2YGSA 2A5YB 2N1FA 4A2WA 1E3YA 3KATA 2HM2Q 4FH0A 1YGOA 1PN5A 4F44A 2IB1A 4O9FA 2NSNA
chains in the Genus database with same CATH topology
4JQWA 4P4HA 2N97A 1N3KA 2DBGA 2DO9A 4RHWA 4IZAB 4P4HI 3MOPK 4A2QA 2XV9A 4N1KA 3YGSC 2NAQA 2N83A 3MOPA 4O6XA 4N1JA 1FADA 3J63A 2BBRA 2OF5H 1UCPA 2MS8A 2DBFA 1ICHA 1D2ZA 2DBHA 2BBZA 2LS7A 1D2ZB 2M5VA 2MB9A 3LQRA 2VGQA 1CWWA 1A1WA 3CL3A 2L6AA 4O9LA 4E9MA 4EWIA 2MPCA 1DGNA 2OF5A 3QF2A 1WMGA 2D96A 2MN4A 3CRDA 2YU0A 4LWDA 4JUPA 1Z6TA 4DWNA 4F42A 2DBDA 2GF5A 1WXPA 1E41A 3MOPG 1CY5A 2N00A 4D8OA 4O7QA 2NZ7A 4M9SA 4NQKA 3T6PA 1NGRA 3J6JA 2KN6A 4RHWE 3LQQA 4ZBWA 2O71A 3EZQB 4I16A 2N80A 2YVIA 4QOBA 1WH4A 4IZ7B 3YGSP 1DDFA 2L9MA 2N7ZA 2KM6A 4UZ0A 1A1ZA 2F1SA 4M9ZA 4M9XA 2A9IA 2LWEA 1C15A 2P1HA 2G7RA 2B1WA 3EZQA 2MJMA 4IZ5E 4N1LA 2MS7A 2LWDA 2YQFA 2YGSA 2A5YB 2N1FA 4A2WA 1E3YA 3KATA 2HM2Q 4FH0A 1YGOA 1PN5A 4F44A 2IB1A 4O9FA 2NSNA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4JQW A;  4P4H A;  2N97 A;  1N3K A;  2DBG A;  2DO9 A;  4RHW A;  4IZA B;  4P4H I;  3MOP K;  4A2Q A;  4N1K A;  3YGS C;  2NAQ A;  2N83 A;  3MOP A;  4O6X A;  4N1J A;  1FAD A;  3J63 A;  2BBR A;  2OF5 H;  1UCP A;  2MS8 A;  2DBF A;  1ICH A;  1D2Z A;  2DBH A;  2BBZ A;  2LS7 A;  1D2Z B;  2M5V A;  2MB9 A;  3LQR A;  2VGQ A;  1CWW A;  1A1W A;  3CL3 A;  2L6A A;  4O9L A;  4E9M A;  4EWI A;  2MPC A;  1DGN A;  2OF5 A;  3QF2 A;  1WMG A;  2D96 A;  2MN4 A;  3CRD A;  2YU0 A;  4LWD A;  4JUP A;  1Z6T A;  4DWN A;  4F42 A;  2DBD A;  2GF5 A;  1WXP A;  1E41 A;  3MOP G;  1CY5 A;  2N00 A;  4D8O A;  4O7Q A;  2NZ7 A;  4M9S A;  4NQK A;  3T6P A;  1NGR A;  3J6J A;  2KN6 A;  4RHW E;  3LQQ A;  4ZBW A;  2O71 A;  3EZQ B;  4I16 A;  2N80 A;  2YVI A;  4QOB A;  1WH4 A;  4IZ7 B;  3YGS P;  1DDF A;  2L9M A;  2N7Z A;  2KM6 A;  4UZ0 A;  1A1Z A;  2F1S A;  4M9Z A;  4M9X A;  2A9I A;  2LWE A;  1C15 A;  2P1H A;  2G7R A;  2B1W A;  3EZQ A;  4IZ5 E;  4N1L A;  2MS7 A;  2LWD A;  2YQF A;  2YGS A;  2A5Y B;  2N1F A;  4A2W A;  1E3Y A;  3KAT A;  2HM2 Q;  4FH0 A;  1YGO A;  1PN5 A;  4F44 A;  2IB1 A;  4O9F A;  2NSN A; 
#chains in the Genus database with same CATH topology
 4JQW A;  4P4H A;  2N97 A;  1N3K A;  2DBG A;  2DO9 A;  4RHW A;  4IZA B;  4P4H I;  3MOP K;  4A2Q A;  2XV9 A;  4N1K A;  3YGS C;  2NAQ A;  2N83 A;  3MOP A;  4O6X A;  4N1J A;  1FAD A;  3J63 A;  2BBR A;  2OF5 H;  1UCP A;  2MS8 A;  2DBF A;  1ICH A;  1D2Z A;  2DBH A;  2BBZ A;  2LS7 A;  1D2Z B;  2M5V A;  2MB9 A;  3LQR A;  2VGQ A;  1CWW A;  1A1W A;  3CL3 A;  2L6A A;  4O9L A;  4E9M A;  4EWI A;  2MPC A;  1DGN A;  2OF5 A;  3QF2 A;  1WMG A;  2D96 A;  2MN4 A;  3CRD A;  2YU0 A;  4LWD A;  4JUP A;  1Z6T A;  4DWN A;  4F42 A;  2DBD A;  2GF5 A;  1WXP A;  1E41 A;  3MOP G;  1CY5 A;  2N00 A;  4D8O A;  4O7Q A;  2NZ7 A;  4M9S A;  4NQK A;  3T6P A;  1NGR A;  3J6J A;  2KN6 A;  4RHW E;  3LQQ A;  4ZBW A;  2O71 A;  3EZQ B;  4I16 A;  2N80 A;  2YVI A;  4QOB A;  1WH4 A;  4IZ7 B;  3YGS P;  1DDF A;  2L9M A;  2N7Z A;  2KM6 A;  4UZ0 A;  1A1Z A;  2F1S A;  4M9Z A;  4M9X A;  2A9I A;  2LWE A;  1C15 A;  2P1H A;  2G7R A;  2B1W A;  3EZQ A;  2MJM A;  4IZ5 E;  4N1L A;  2MS7 A;  2LWD A;  2YQF A;  2YGS A;  2A5Y B;  2N1F A;  4A2W A;  1E3Y A;  3KAT A;  2HM2 Q;  4FH0 A;  1YGO A;  1PN5 A;  4F44 A;  2IB1 A;  4O9F A;  2NSN A; 
#chains in the Genus database with same CATH homology
 4JQW A;  4P4H A;  2N97 A;  1N3K A;  2DBG A;  2DO9 A;  4RHW A;  4IZA B;  4P4H I;  3MOP K;  4A2Q A;  2XV9 A;  4N1K A;  3YGS C;  2NAQ A;  2N83 A;  3MOP A;  4O6X A;  4N1J A;  1FAD A;  3J63 A;  2BBR A;  2OF5 H;  1UCP A;  2MS8 A;  2DBF A;  1ICH A;  1D2Z A;  2DBH A;  2BBZ A;  2LS7 A;  1D2Z B;  2M5V A;  2MB9 A;  3LQR A;  2VGQ A;  1CWW A;  1A1W A;  3CL3 A;  2L6A A;  4O9L A;  4E9M A;  4EWI A;  2MPC A;  1DGN A;  2OF5 A;  3QF2 A;  1WMG A;  2D96 A;  2MN4 A;  3CRD A;  2YU0 A;  4LWD A;  4JUP A;  1Z6T A;  4DWN A;  4F42 A;  2DBD A;  2GF5 A;  1WXP A;  1E41 A;  3MOP G;  1CY5 A;  2N00 A;  4D8O A;  4O7Q A;  2NZ7 A;  4M9S A;  4NQK A;  3T6P A;  1NGR A;  3J6J A;  2KN6 A;  4RHW E;  3LQQ A;  4ZBW A;  2O71 A;  3EZQ B;  4I16 A;  2N80 A;  2YVI A;  4QOB A;  1WH4 A;  4IZ7 B;  3YGS P;  1DDF A;  2L9M A;  2N7Z A;  2KM6 A;  4UZ0 A;  1A1Z A;  2F1S A;  4M9Z A;  4M9X A;  2A9I A;  2LWE A;  1C15 A;  2P1H A;  2G7R A;  2B1W A;  3EZQ A;  2MJM A;  4IZ5 E;  4N1L A;  2MS7 A;  2LWD A;  2YQF A;  2YGS A;  2A5Y B;  2N1F A;  4A2W A;  1E3Y A;  3KAT A;  2HM2 Q;  4FH0 A;  1YGO A;  1PN5 A;  4F44 A;  2IB1 A;  4O9F A;  2NSN A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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