2F1SA

Crystal structure of a viral flip mc159
Total Genus 71
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
71
sequence length
177
structure length
177
Chain Sequence
VPSLPFLRHLLEELDSHEDSLLLFLCHDAAPGCTTVTQALCSLSQQRKLTLAALVEMLYVLQRMDLLKSRFGLSKEGAEQLLGTSFLTRYRKLMVCVGEELDSSELRALRLFACNLNPSLSTALSESSRFVELVLALENVGLVSPSSVSVLADMLRTLRRLDLCQQLVEYEQQEQAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Apoptosis
source organism Molluscum contagiosum virus subtype 1
publication title Crystal Structure of a Viral FLIP: INSIGHTS INTO FLIP-MEDIATED INHIBITION OF DEATH RECEPTOR SIGNALING.
pubmed doi rcsb
molecule keywords Viral CASP8 and FADD-like apoptosis regulator
total genus 71
structure length 177
sequence length 177
ec nomenclature
pdb deposition date 2005-11-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01335 DED Death effector domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.533.10 Mainly Alpha Orthogonal Bundle Death Domain, Fas Death Domain, Fas 2f1sA02
1.10.533.10 Mainly Alpha Orthogonal Bundle Death Domain, Fas Death Domain, Fas 2f1sA01
4I16A 3EZQB 2MS7A 2NAQA 4A2WA 1N3KA 1CY5A 4M9SA 4O9FA 3MOPK 2MB9A 4QOBA 4IZ7B 4RHWE 4F44A 2MN4A 4UZ0A 4A2QA 3MOPG 4N1JA 3J6JA 4O6XA 2A9IA 4ZBWA 4P4HA 4IZ5E 4M9ZA 2F1SA 2YU0A 1DGNA 2MS8A 3T6PA 2N00A 2OF5H 1ICHA 2NZ7A 4D8OA 1Z6TA 1FADA 2GF5A 2BBRA 1CWWA 3YGSC 2VGQA 4DWNA 1D2ZB 4LWDA 2O71A 2DBDA 2LWDA 2NSNA 2OF5A 4O9LA 4E9MA 2KN6A 4NQKA 4F42A 1A1WA 3EZQA 2N97A 1NGRA 2D96A 2M5VA 3LQRA 4FH0A 4JUPA 1UCPA 3QF2A 1WH4A 2L6AA 2BBZA 1PN5A 2YQFA 2KM6A 2DBHA 4N1LA 2LWEA 2DBGA 2N7ZA 2P1HA 3MOPA 2IB1A 1YGOA 3KATA 4M9XA 1WMGA 3LQQA 2DO9A 1WXPA 3J63A 3YGSP 2L9MA 1E3YA 4RHWA 1E41A 4IZAB 2N1FA 3CRDA 2A5YB 2DBFA 2YVIA 2G7RA 2B1WA 2HM2Q 2MPCA 4O7QA 2LS7A 3CL3A 4JQWA 4EWIA 4N1KA 4P4HI 1A1ZA 1C15A 1DDFA 2N83A 2YGSA 1D2ZA 2N80A
chains in the Genus database with same CATH superfamily
4I16A 3EZQB 2MS7A 2NAQA 4A2WA 1N3KA 1CY5A 4M9SA 4O9FA 3MOPK 2MB9A 4QOBA 4IZ7B 4RHWE 4F44A 2MN4A 4UZ0A 4A2QA 3MOPG 4N1JA 3J6JA 4O6XA 2A9IA 4ZBWA 4P4HA 4IZ5E 4M9ZA 2F1SA 2YU0A 1DGNA 2MS8A 3T6PA 2N00A 2OF5H 1ICHA 2NZ7A 4D8OA 1Z6TA 1FADA 2GF5A 2BBRA 1CWWA 3YGSC 2VGQA 4DWNA 1D2ZB 4LWDA 2O71A 2DBDA 2LWDA 2NSNA 2OF5A 4O9LA 4E9MA 2KN6A 4NQKA 4F42A 1A1WA 3EZQA 2N97A 1NGRA 2D96A 2M5VA 3LQRA 4FH0A 4JUPA 1UCPA 3QF2A 1WH4A 2L6AA 2BBZA 1PN5A 2YQFA 2KM6A 2DBHA 2XV9A 4N1LA 2LWEA 2DBGA 2MJMA 2N7ZA 2P1HA 3MOPA 2IB1A 1YGOA 3KATA 4M9XA 1WMGA 3LQQA 2DO9A 1WXPA 3J63A 3YGSP 2L9MA 1E3YA 4RHWA 1E41A 4IZAB 2N1FA 3CRDA 2A5YB 2DBFA 2YVIA 2G7RA 2B1WA 2HM2Q 2MPCA 4O7QA 2LS7A 3CL3A 4JQWA 4EWIA 4N1KA 4P4HI 1A1ZA 1C15A 1DDFA 2N83A 2YGSA 1D2ZA 2N80A
chains in the Genus database with same CATH topology
4I16A 3EZQB 2MS7A 2NAQA 4A2WA 1N3KA 1CY5A 4M9SA 4O9FA 3MOPK 2MB9A 4QOBA 4IZ7B 4RHWE 4F44A 2MN4A 4UZ0A 4A2QA 3MOPG 4N1JA 3J6JA 4O6XA 2A9IA 4ZBWA 4P4HA 4IZ5E 4M9ZA 2F1SA 2YU0A 1DGNA 2MS8A 3T6PA 2N00A 2OF5H 1ICHA 2NZ7A 4D8OA 1Z6TA 1FADA 2GF5A 2BBRA 1CWWA 3YGSC 2VGQA 4DWNA 1D2ZB 4LWDA 2O71A 2DBDA 2LWDA 2NSNA 2OF5A 4O9LA 4E9MA 2KN6A 4NQKA 4F42A 1A1WA 3EZQA 2N97A 1NGRA 2D96A 2M5VA 3LQRA 4FH0A 4JUPA 1UCPA 3QF2A 1WH4A 2L6AA 2BBZA 1PN5A 2YQFA 2KM6A 2DBHA 2XV9A 4N1LA 2LWEA 2DBGA 2MJMA 2N7ZA 2P1HA 3MOPA 2IB1A 1YGOA 3KATA 4M9XA 1WMGA 3LQQA 2DO9A 1WXPA 3J63A 3YGSP 2L9MA 1E3YA 4RHWA 1E41A 4IZAB 2N1FA 3CRDA 2A5YB 2DBFA 2YVIA 2G7RA 2B1WA 2HM2Q 2MPCA 4O7QA 2LS7A 3CL3A 4JQWA 4EWIA 4N1KA 4P4HI 1A1ZA 1C15A 1DDFA 2N83A 2YGSA 1D2ZA 2N80A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4I16 A;  3EZQ B;  2MS7 A;  2NAQ A;  4A2W A;  1N3K A;  1CY5 A;  4M9S A;  4O9F A;  3MOP K;  2MB9 A;  4QOB A;  4IZ7 B;  4RHW E;  4F44 A;  2MN4 A;  4UZ0 A;  4A2Q A;  3MOP G;  4N1J A;  3J6J A;  4O6X A;  2A9I A;  4ZBW A;  4P4H A;  4IZ5 E;  4M9Z A;  2F1S A;  2YU0 A;  1DGN A;  2MS8 A;  3T6P A;  2N00 A;  2OF5 H;  1ICH A;  2NZ7 A;  4D8O A;  1Z6T A;  1FAD A;  2GF5 A;  2BBR A;  1CWW A;  3YGS C;  2VGQ A;  4DWN A;  1D2Z B;  4LWD A;  2O71 A;  2DBD A;  2LWD A;  2NSN A;  2OF5 A;  4O9L A;  4E9M A;  2KN6 A;  4NQK A;  4F42 A;  1A1W A;  3EZQ A;  2N97 A;  1NGR A;  2D96 A;  2M5V A;  3LQR A;  4FH0 A;  4JUP A;  1UCP A;  3QF2 A;  1WH4 A;  2L6A A;  2BBZ A;  1PN5 A;  2YQF A;  2KM6 A;  2DBH A;  4N1L A;  2LWE A;  2DBG A;  2N7Z A;  2P1H A;  3MOP A;  2IB1 A;  1YGO A;  3KAT A;  4M9X A;  1WMG A;  3LQQ A;  2DO9 A;  1WXP A;  3J63 A;  3YGS P;  2L9M A;  1E3Y A;  4RHW A;  1E41 A;  4IZA B;  2N1F A;  3CRD A;  2A5Y B;  2DBF A;  2YVI A;  2G7R A;  2B1W A;  2HM2 Q;  2MPC A;  4O7Q A;  2LS7 A;  3CL3 A;  4JQW A;  4EWI A;  4N1K A;  4P4H I;  1A1Z A;  1C15 A;  1DDF A;  2N83 A;  2YGS A;  1D2Z A;  2N80 A; 
#chains in the Genus database with same CATH topology
 4I16 A;  3EZQ B;  2MS7 A;  2NAQ A;  4A2W A;  1N3K A;  1CY5 A;  4M9S A;  4O9F A;  3MOP K;  2MB9 A;  4QOB A;  4IZ7 B;  4RHW E;  4F44 A;  2MN4 A;  4UZ0 A;  4A2Q A;  3MOP G;  4N1J A;  3J6J A;  4O6X A;  2A9I A;  4ZBW A;  4P4H A;  4IZ5 E;  4M9Z A;  2F1S A;  2YU0 A;  1DGN A;  2MS8 A;  3T6P A;  2N00 A;  2OF5 H;  1ICH A;  2NZ7 A;  4D8O A;  1Z6T A;  1FAD A;  2GF5 A;  2BBR A;  1CWW A;  3YGS C;  2VGQ A;  4DWN A;  1D2Z B;  4LWD A;  2O71 A;  2DBD A;  2LWD A;  2NSN A;  2OF5 A;  4O9L A;  4E9M A;  2KN6 A;  4NQK A;  4F42 A;  1A1W A;  3EZQ A;  2N97 A;  1NGR A;  2D96 A;  2M5V A;  3LQR A;  4FH0 A;  4JUP A;  1UCP A;  3QF2 A;  1WH4 A;  2L6A A;  2BBZ A;  1PN5 A;  2YQF A;  2KM6 A;  2DBH A;  2XV9 A;  4N1L A;  2LWE A;  2DBG A;  2MJM A;  2N7Z A;  2P1H A;  3MOP A;  2IB1 A;  1YGO A;  3KAT A;  4M9X A;  1WMG A;  3LQQ A;  2DO9 A;  1WXP A;  3J63 A;  3YGS P;  2L9M A;  1E3Y A;  4RHW A;  1E41 A;  4IZA B;  2N1F A;  3CRD A;  2A5Y B;  2DBF A;  2YVI A;  2G7R A;  2B1W A;  2HM2 Q;  2MPC A;  4O7Q A;  2LS7 A;  3CL3 A;  4JQW A;  4EWI A;  4N1K A;  4P4H I;  1A1Z A;  1C15 A;  1DDF A;  2N83 A;  2YGS A;  1D2Z A;  2N80 A; 
#chains in the Genus database with same CATH homology
 4I16 A;  3EZQ B;  2MS7 A;  2NAQ A;  4A2W A;  1N3K A;  1CY5 A;  4M9S A;  4O9F A;  3MOP K;  2MB9 A;  4QOB A;  4IZ7 B;  4RHW E;  4F44 A;  2MN4 A;  4UZ0 A;  4A2Q A;  3MOP G;  4N1J A;  3J6J A;  4O6X A;  2A9I A;  4ZBW A;  4P4H A;  4IZ5 E;  4M9Z A;  2F1S A;  2YU0 A;  1DGN A;  2MS8 A;  3T6P A;  2N00 A;  2OF5 H;  1ICH A;  2NZ7 A;  4D8O A;  1Z6T A;  1FAD A;  2GF5 A;  2BBR A;  1CWW A;  3YGS C;  2VGQ A;  4DWN A;  1D2Z B;  4LWD A;  2O71 A;  2DBD A;  2LWD A;  2NSN A;  2OF5 A;  4O9L A;  4E9M A;  2KN6 A;  4NQK A;  4F42 A;  1A1W A;  3EZQ A;  2N97 A;  1NGR A;  2D96 A;  2M5V A;  3LQR A;  4FH0 A;  4JUP A;  1UCP A;  3QF2 A;  1WH4 A;  2L6A A;  2BBZ A;  1PN5 A;  2YQF A;  2KM6 A;  2DBH A;  2XV9 A;  4N1L A;  2LWE A;  2DBG A;  2MJM A;  2N7Z A;  2P1H A;  3MOP A;  2IB1 A;  1YGO A;  3KAT A;  4M9X A;  1WMG A;  3LQQ A;  2DO9 A;  1WXP A;  3J63 A;  3YGS P;  2L9M A;  1E3Y A;  4RHW A;  1E41 A;  4IZA B;  2N1F A;  3CRD A;  2A5Y B;  2DBF A;  2YVI A;  2G7R A;  2B1W A;  2HM2 Q;  2MPC A;  4O7Q A;  2LS7 A;  3CL3 A;  4JQW A;  4EWI A;  4N1K A;  4P4H I;  1A1Z A;  1C15 A;  1DDF A;  2N83 A;  2YGS A;  1D2Z A;  2N80 A; 
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similar chains in the pdb database (?% sequence similarity)

 
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