2GF5A

Structure of intact fadd (mort1)
Total Genus 66
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
66
sequence length
191
structure length
191
Chain Sequence
SDPFLVLLHSVSSSLSSSELTELKYLCLGRVGKRKLERVQSGLDLFSMLLEQNDLEPGHTELLRELLASLRRHDLLRRVDDFEAGAAAGAAPGEEDLCAAFNVICDNVGKDWRRLARQLKVSDTKIDSIEDRYPRNLTERVRESLRIWKNTEKENATVAHLVGALRSCQMNLVADLVQEVQQARDLQNRSG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Structure of FADD and Its Mode of Interaction with Procaspase-8
pubmed doi rcsb
molecule tags Apoptosis
source organism Homo sapiens
molecule keywords FADD protein
total genus 66
structure length 191
sequence length 191
ec nomenclature
pdb deposition date 2006-03-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00531 Death Death domain
A PF01335 DED Death effector domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.533.10 Mainly Alpha Orthogonal Bundle Death Domain, Fas Death Domain, Fas 2gf5A02
1.10.533.10 Mainly Alpha Orthogonal Bundle Death Domain, Fas Death Domain, Fas 2gf5A01
2F1SA 1ICHA 4RHWE 2NZ7A 3T6PA 3LQQA 1NGRA 3J63A 4JQWA 4F44A 2DBFA 1DDFA 4IZAB 2OF5H 1E3YA 2N97A 1A1ZA 3EZQB 4JUPA 4N1LA 4RHWA 2MPCA 2LWDA 3YGSP 4EWIA 2GF5A 4M9XA 4O6XA 4A2WA 4O9FA 1WMGA 1Z6TA 2MS7A 2L9MA 4ZBWA 4E9MA 2N1FA 3CL3A 2DBHA 2LS7A 2LWEA 4NQKA 4IZ5E 3KATA 1N3KA 1CY5A 4P4HI 4A2QA 2L6AA 2D96A 4QOBA 4D8OA 1A1WA 2KN6A 3MOPA 4O7QA 2M5VA 4M9SA 1C15A 2N83A 1FADA 1WH4A 2YU0A 3QF2A 2YQFA 1D2ZA 2YVIA 2A9IA 3YGSC 2IB1A 1D2ZB 1E41A 2OF5A 2BBZA 2DBDA 1UCPA 3CRDA 1DGNA 1PN5A 2P1HA 4M9ZA 2B1WA 1YGOA 3MOPG 4LWDA 4P4HA 2BBRA 4N1JA 2VGQA 2MN4A 2N7ZA 4UZ0A 4IZ7B 3LQRA 3EZQA 2DBGA 2NSNA 1WXPA 3MOPK 2MS8A 2N80A 2N00A 2A5YB 4N1KA 4I16A 2KM6A 4O9LA 3J6JA 1CWWA 4F42A 4FH0A 2MB9A 2O71A 2YGSA 4DWNA 2G7RA 2DO9A 2HM2Q 2NAQA
chains in the Genus database with same CATH superfamily
2F1SA 1ICHA 4RHWE 2NZ7A 3T6PA 3LQQA 1NGRA 3J63A 4JQWA 4F44A 2DBFA 1DDFA 4IZAB 2OF5H 2XV9A 1E3YA 2N97A 1A1ZA 3EZQB 4JUPA 4N1LA 4RHWA 2MPCA 2LWDA 3YGSP 4EWIA 2GF5A 4M9XA 4O6XA 4A2WA 4O9FA 1WMGA 1Z6TA 2MS7A 2L9MA 4ZBWA 4E9MA 2N1FA 3CL3A 2DBHA 2LS7A 2LWEA 4NQKA 4IZ5E 3KATA 1N3KA 1CY5A 4P4HI 4A2QA 2L6AA 2D96A 4QOBA 4D8OA 1A1WA 2KN6A 3MOPA 4O7QA 2M5VA 4M9SA 1C15A 2N83A 1FADA 1WH4A 2YU0A 3QF2A 2YQFA 2MJMA 1D2ZA 2YVIA 2A9IA 3YGSC 2IB1A 1D2ZB 1E41A 2OF5A 2BBZA 2DBDA 1UCPA 3CRDA 1DGNA 1PN5A 2P1HA 4M9ZA 2B1WA 1YGOA 3MOPG 4LWDA 4P4HA 2BBRA 4N1JA 2VGQA 2MN4A 2N7ZA 4UZ0A 4IZ7B 3LQRA 3EZQA 2DBGA 2NSNA 1WXPA 3MOPK 2MS8A 2N80A 2N00A 2A5YB 4N1KA 4I16A 2KM6A 4O9LA 3J6JA 1CWWA 4F42A 4FH0A 2MB9A 2O71A 2YGSA 4DWNA 2G7RA 2DO9A 2HM2Q 2NAQA
chains in the Genus database with same CATH topology
2F1SA 1ICHA 4RHWE 2NZ7A 3T6PA 3LQQA 1NGRA 3J63A 4JQWA 4F44A 2DBFA 1DDFA 4IZAB 2OF5H 2XV9A 1E3YA 2N97A 1A1ZA 3EZQB 4JUPA 4N1LA 4RHWA 2MPCA 2LWDA 3YGSP 4EWIA 2GF5A 4M9XA 4O6XA 4A2WA 4O9FA 1WMGA 1Z6TA 2MS7A 2L9MA 4ZBWA 4E9MA 2N1FA 3CL3A 2DBHA 2LS7A 2LWEA 4NQKA 4IZ5E 3KATA 1N3KA 1CY5A 4P4HI 4A2QA 2L6AA 2D96A 4QOBA 4D8OA 1A1WA 2KN6A 3MOPA 4O7QA 2M5VA 4M9SA 1C15A 2N83A 1FADA 1WH4A 2YU0A 3QF2A 2YQFA 2MJMA 1D2ZA 2YVIA 2A9IA 3YGSC 2IB1A 1D2ZB 1E41A 2OF5A 2BBZA 2DBDA 1UCPA 3CRDA 1DGNA 1PN5A 2P1HA 4M9ZA 2B1WA 1YGOA 3MOPG 4LWDA 4P4HA 2BBRA 4N1JA 2VGQA 2MN4A 2N7ZA 4UZ0A 4IZ7B 3LQRA 3EZQA 2DBGA 2NSNA 1WXPA 3MOPK 2MS8A 2N80A 2N00A 2A5YB 4N1KA 4I16A 2KM6A 4O9LA 3J6JA 1CWWA 4F42A 4FH0A 2MB9A 2O71A 2YGSA 4DWNA 2G7RA 2DO9A 2HM2Q 2NAQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2F1S A;  1ICH A;  4RHW E;  2NZ7 A;  3T6P A;  3LQQ A;  1NGR A;  3J63 A;  4JQW A;  4F44 A;  2DBF A;  1DDF A;  4IZA B;  2OF5 H;  1E3Y A;  2N97 A;  1A1Z A;  3EZQ B;  4JUP A;  4N1L A;  4RHW A;  2MPC A;  2LWD A;  3YGS P;  4EWI A;  2GF5 A;  4M9X A;  4O6X A;  4A2W A;  4O9F A;  1WMG A;  1Z6T A;  2MS7 A;  2L9M A;  4ZBW A;  4E9M A;  2N1F A;  3CL3 A;  2DBH A;  2LS7 A;  2LWE A;  4NQK A;  4IZ5 E;  3KAT A;  1N3K A;  1CY5 A;  4P4H I;  4A2Q A;  2L6A A;  2D96 A;  4QOB A;  4D8O A;  1A1W A;  2KN6 A;  3MOP A;  4O7Q A;  2M5V A;  4M9S A;  1C15 A;  2N83 A;  1FAD A;  1WH4 A;  2YU0 A;  3QF2 A;  2YQF A;  1D2Z A;  2YVI A;  2A9I A;  3YGS C;  2IB1 A;  1D2Z B;  1E41 A;  2OF5 A;  2BBZ A;  2DBD A;  1UCP A;  3CRD A;  1DGN A;  1PN5 A;  2P1H A;  4M9Z A;  2B1W A;  1YGO A;  3MOP G;  4LWD A;  4P4H A;  2BBR A;  4N1J A;  2VGQ A;  2MN4 A;  2N7Z A;  4UZ0 A;  4IZ7 B;  3LQR A;  3EZQ A;  2DBG A;  2NSN A;  1WXP A;  3MOP K;  2MS8 A;  2N80 A;  2N00 A;  2A5Y B;  4N1K A;  4I16 A;  2KM6 A;  4O9L A;  3J6J A;  1CWW A;  4F42 A;  4FH0 A;  2MB9 A;  2O71 A;  2YGS A;  4DWN A;  2G7R A;  2DO9 A;  2HM2 Q;  2NAQ A; 
#chains in the Genus database with same CATH topology
 2F1S A;  1ICH A;  4RHW E;  2NZ7 A;  3T6P A;  3LQQ A;  1NGR A;  3J63 A;  4JQW A;  4F44 A;  2DBF A;  1DDF A;  4IZA B;  2OF5 H;  2XV9 A;  1E3Y A;  2N97 A;  1A1Z A;  3EZQ B;  4JUP A;  4N1L A;  4RHW A;  2MPC A;  2LWD A;  3YGS P;  4EWI A;  2GF5 A;  4M9X A;  4O6X A;  4A2W A;  4O9F A;  1WMG A;  1Z6T A;  2MS7 A;  2L9M A;  4ZBW A;  4E9M A;  2N1F A;  3CL3 A;  2DBH A;  2LS7 A;  2LWE A;  4NQK A;  4IZ5 E;  3KAT A;  1N3K A;  1CY5 A;  4P4H I;  4A2Q A;  2L6A A;  2D96 A;  4QOB A;  4D8O A;  1A1W A;  2KN6 A;  3MOP A;  4O7Q A;  2M5V A;  4M9S A;  1C15 A;  2N83 A;  1FAD A;  1WH4 A;  2YU0 A;  3QF2 A;  2YQF A;  2MJM A;  1D2Z A;  2YVI A;  2A9I A;  3YGS C;  2IB1 A;  1D2Z B;  1E41 A;  2OF5 A;  2BBZ A;  2DBD A;  1UCP A;  3CRD A;  1DGN A;  1PN5 A;  2P1H A;  4M9Z A;  2B1W A;  1YGO A;  3MOP G;  4LWD A;  4P4H A;  2BBR A;  4N1J A;  2VGQ A;  2MN4 A;  2N7Z A;  4UZ0 A;  4IZ7 B;  3LQR A;  3EZQ A;  2DBG A;  2NSN A;  1WXP A;  3MOP K;  2MS8 A;  2N80 A;  2N00 A;  2A5Y B;  4N1K A;  4I16 A;  2KM6 A;  4O9L A;  3J6J A;  1CWW A;  4F42 A;  4FH0 A;  2MB9 A;  2O71 A;  2YGS A;  4DWN A;  2G7R A;  2DO9 A;  2HM2 Q;  2NAQ A; 
#chains in the Genus database with same CATH homology
 2F1S A;  1ICH A;  4RHW E;  2NZ7 A;  3T6P A;  3LQQ A;  1NGR A;  3J63 A;  4JQW A;  4F44 A;  2DBF A;  1DDF A;  4IZA B;  2OF5 H;  2XV9 A;  1E3Y A;  2N97 A;  1A1Z A;  3EZQ B;  4JUP A;  4N1L A;  4RHW A;  2MPC A;  2LWD A;  3YGS P;  4EWI A;  2GF5 A;  4M9X A;  4O6X A;  4A2W A;  4O9F A;  1WMG A;  1Z6T A;  2MS7 A;  2L9M A;  4ZBW A;  4E9M A;  2N1F A;  3CL3 A;  2DBH A;  2LS7 A;  2LWE A;  4NQK A;  4IZ5 E;  3KAT A;  1N3K A;  1CY5 A;  4P4H I;  4A2Q A;  2L6A A;  2D96 A;  4QOB A;  4D8O A;  1A1W A;  2KN6 A;  3MOP A;  4O7Q A;  2M5V A;  4M9S A;  1C15 A;  2N83 A;  1FAD A;  1WH4 A;  2YU0 A;  3QF2 A;  2YQF A;  2MJM A;  1D2Z A;  2YVI A;  2A9I A;  3YGS C;  2IB1 A;  1D2Z B;  1E41 A;  2OF5 A;  2BBZ A;  2DBD A;  1UCP A;  3CRD A;  1DGN A;  1PN5 A;  2P1H A;  4M9Z A;  2B1W A;  1YGO A;  3MOP G;  4LWD A;  4P4H A;  2BBR A;  4N1J A;  2VGQ A;  2MN4 A;  2N7Z A;  4UZ0 A;  4IZ7 B;  3LQR A;  3EZQ A;  2DBG A;  2NSN A;  1WXP A;  3MOP K;  2MS8 A;  2N80 A;  2N00 A;  2A5Y B;  4N1K A;  4I16 A;  2KM6 A;  4O9L A;  3J6J A;  1CWW A;  4F42 A;  4FH0 A;  2MB9 A;  2O71 A;  2YGS A;  4DWN A;  2G7R A;  2DO9 A;  2HM2 Q;  2NAQ A; 
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similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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