2M5VA

Three-dimensional structure of human nlrp10/pynod pyrin domain
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
102
structure length
102
Chain Sequence
GAMAMAKARKPREALLWALSDLEENDFKKLKFYLRDMTLSEGQPPLARGELEGLIPVDLAELLISKYGEKEAVKVVLKGLKVMNLLELVDQLSHICLHDYRE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Three-Dimensional Structure of Human NLRP10/PYNOD Pyrin Domain Reveals a Homotypic Interaction Site Distinct from Its Mouse Homologue.
pubmed doi rcsb
molecule tags Immune system
source organism Homo sapiens
molecule keywords NACHT, LRR and PYD domains-containing protein 10
total genus 23
structure length 102
sequence length 102
ec nomenclature
pdb deposition date 2013-03-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02758 PYRIN PAAD/DAPIN/Pyrin domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.533.10 Mainly Alpha Orthogonal Bundle Death Domain, Fas Death Domain, Fas 2m5vA00
4ZBWA 4IZ7B 4O6XA 4I16A 2NSNA 2HM2Q 4P4HI 4F42A 2MS8A 2M5VA 1ICHA 1E41A 4P4HA 1NGRA 4O9LA 4N1JA 2MN4A 2YVIA 4IZAB 2O71A 2DO9A 2NZ7A 4F44A 2B1WA 1WXPA 2YGSA 4A2QA 1A1ZA 4O7QA 4M9SA 3EZQB 4JUPA 2IB1A 4RHWA 1WMGA 4E9MA 4N1LA 2MB9A 3J6JA 2DBDA 2OF5A 2L6AA 3MOPG 2DBGA 1D2ZB 1C15A 2P1HA 3EZQA 1A1WA 3MOPA 4JQWA 1N3KA 2A9IA 4QOBA 2BBZA 2N00A 4M9XA 4FH0A 4N1KA 1FADA 2OF5H 2KM6A 2MPCA 3QF2A 1DGNA 4RHWE 2KN6A 1D2ZA 2N83A 2LWEA 1CY5A 4DWNA 2GF5A 3T6PA 3MOPK 1WH4A 2N97A 4LWDA 2L9MA 4A2WA 2F1SA 2G7RA 3KATA 2NAQA 2D96A 4IZ5E 2A5YB 2MS7A 2VGQA 2N1FA 2LS7A 2DBFA 2N7ZA 4O9FA 4M9ZA 3LQQA 3LQRA 2YQFA 4UZ0A 1DDFA 2N80A 3CRDA 3YGSP 2LWDA 4NQKA 3YGSC 1UCPA 2BBRA 2DBHA 4EWIA 1PN5A 3J63A 1CWWA 4D8OA 3CL3A 1Z6TA 1YGOA 2YU0A 1E3YA
chains in the Genus database with same CATH superfamily
2MJMA 4ZBWA 4IZ7B 4O6XA 4I16A 2NSNA 2HM2Q 4P4HI 4F42A 2MS8A 2M5VA 1ICHA 1E41A 4P4HA 1NGRA 4O9LA 4N1JA 2MN4A 2YVIA 4IZAB 2O71A 2DO9A 2NZ7A 4F44A 2B1WA 1WXPA 2YGSA 4A2QA 1A1ZA 4O7QA 4M9SA 3EZQB 4JUPA 2IB1A 4RHWA 1WMGA 4E9MA 4N1LA 2MB9A 3J6JA 2DBDA 2OF5A 2L6AA 3MOPG 2DBGA 1D2ZB 1C15A 2P1HA 3EZQA 1A1WA 3MOPA 4JQWA 1N3KA 2A9IA 4QOBA 2BBZA 2N00A 4M9XA 4FH0A 4N1KA 1FADA 2OF5H 2KM6A 2MPCA 3QF2A 1DGNA 4RHWE 2KN6A 1D2ZA 2N83A 2LWEA 1CY5A 4DWNA 2GF5A 3T6PA 3MOPK 1WH4A 2N97A 4LWDA 2L9MA 4A2WA 2F1SA 2G7RA 3KATA 2NAQA 2D96A 4IZ5E 2A5YB 2MS7A 2VGQA 2N1FA 2LS7A 2DBFA 2N7ZA 2XV9A 4M9ZA 4O9FA 3LQQA 3LQRA 2YQFA 4UZ0A 1DDFA 2N80A 3CRDA 3YGSP 2LWDA 4NQKA 3YGSC 1UCPA 2BBRA 2DBHA 4EWIA 1PN5A 3J63A 1CWWA 4D8OA 3CL3A 1Z6TA 1YGOA 2YU0A 1E3YA
chains in the Genus database with same CATH topology
2MJMA 4ZBWA 4IZ7B 4O6XA 4I16A 2NSNA 2HM2Q 4P4HI 4F42A 2MS8A 2M5VA 1ICHA 1E41A 4P4HA 1NGRA 4O9LA 4N1JA 2MN4A 2YVIA 4IZAB 2O71A 2DO9A 2NZ7A 4F44A 2B1WA 1WXPA 2YGSA 4A2QA 1A1ZA 4O7QA 4M9SA 3EZQB 4JUPA 2IB1A 4RHWA 1WMGA 4E9MA 4N1LA 2MB9A 3J6JA 2DBDA 2OF5A 2L6AA 3MOPG 2DBGA 1D2ZB 1C15A 2P1HA 3EZQA 1A1WA 3MOPA 4JQWA 1N3KA 2A9IA 4QOBA 2BBZA 2N00A 4M9XA 4FH0A 4N1KA 1FADA 2OF5H 2KM6A 2MPCA 3QF2A 1DGNA 4RHWE 2KN6A 1D2ZA 2N83A 2LWEA 1CY5A 4DWNA 2GF5A 3T6PA 3MOPK 1WH4A 2N97A 4LWDA 2L9MA 4A2WA 2F1SA 2G7RA 3KATA 2NAQA 2D96A 4IZ5E 2A5YB 2MS7A 2VGQA 2N1FA 2LS7A 2DBFA 2N7ZA 2XV9A 4M9ZA 4O9FA 3LQQA 3LQRA 2YQFA 4UZ0A 1DDFA 2N80A 3CRDA 3YGSP 2LWDA 4NQKA 3YGSC 1UCPA 2BBRA 2DBHA 4EWIA 1PN5A 3J63A 1CWWA 4D8OA 3CL3A 1Z6TA 1YGOA 2YU0A 1E3YA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4ZBW A;  4IZ7 B;  4O6X A;  4I16 A;  2NSN A;  2HM2 Q;  4P4H I;  4F42 A;  2MS8 A;  2M5V A;  1ICH A;  1E41 A;  4P4H A;  1NGR A;  4O9L A;  4N1J A;  2MN4 A;  2YVI A;  4IZA B;  2O71 A;  2DO9 A;  2NZ7 A;  4F44 A;  2B1W A;  1WXP A;  2YGS A;  4A2Q A;  1A1Z A;  4O7Q A;  4M9S A;  3EZQ B;  4JUP A;  2IB1 A;  4RHW A;  1WMG A;  4E9M A;  4N1L A;  2MB9 A;  3J6J A;  2DBD A;  2OF5 A;  2L6A A;  3MOP G;  2DBG A;  1D2Z B;  1C15 A;  2P1H A;  3EZQ A;  1A1W A;  3MOP A;  4JQW A;  1N3K A;  2A9I A;  4QOB A;  2BBZ A;  2N00 A;  4M9X A;  4FH0 A;  4N1K A;  1FAD A;  2OF5 H;  2KM6 A;  2MPC A;  3QF2 A;  1DGN A;  4RHW E;  2KN6 A;  1D2Z A;  2N83 A;  2LWE A;  1CY5 A;  4DWN A;  2GF5 A;  3T6P A;  3MOP K;  1WH4 A;  2N97 A;  4LWD A;  2L9M A;  4A2W A;  2F1S A;  2G7R A;  3KAT A;  2NAQ A;  2D96 A;  4IZ5 E;  2A5Y B;  2MS7 A;  2VGQ A;  2N1F A;  2LS7 A;  2DBF A;  2N7Z A;  4O9F A;  4M9Z A;  3LQQ A;  3LQR A;  2YQF A;  4UZ0 A;  1DDF A;  2N80 A;  3CRD A;  3YGS P;  2LWD A;  4NQK A;  3YGS C;  1UCP A;  2BBR A;  2DBH A;  4EWI A;  1PN5 A;  3J63 A;  1CWW A;  4D8O A;  3CL3 A;  1Z6T A;  1YGO A;  2YU0 A;  1E3Y A; 
#chains in the Genus database with same CATH topology
 2MJM A;  4ZBW A;  4IZ7 B;  4O6X A;  4I16 A;  2NSN A;  2HM2 Q;  4P4H I;  4F42 A;  2MS8 A;  2M5V A;  1ICH A;  1E41 A;  4P4H A;  1NGR A;  4O9L A;  4N1J A;  2MN4 A;  2YVI A;  4IZA B;  2O71 A;  2DO9 A;  2NZ7 A;  4F44 A;  2B1W A;  1WXP A;  2YGS A;  4A2Q A;  1A1Z A;  4O7Q A;  4M9S A;  3EZQ B;  4JUP A;  2IB1 A;  4RHW A;  1WMG A;  4E9M A;  4N1L A;  2MB9 A;  3J6J A;  2DBD A;  2OF5 A;  2L6A A;  3MOP G;  2DBG A;  1D2Z B;  1C15 A;  2P1H A;  3EZQ A;  1A1W A;  3MOP A;  4JQW A;  1N3K A;  2A9I A;  4QOB A;  2BBZ A;  2N00 A;  4M9X A;  4FH0 A;  4N1K A;  1FAD A;  2OF5 H;  2KM6 A;  2MPC A;  3QF2 A;  1DGN A;  4RHW E;  2KN6 A;  1D2Z A;  2N83 A;  2LWE A;  1CY5 A;  4DWN A;  2GF5 A;  3T6P A;  3MOP K;  1WH4 A;  2N97 A;  4LWD A;  2L9M A;  4A2W A;  2F1S A;  2G7R A;  3KAT A;  2NAQ A;  2D96 A;  4IZ5 E;  2A5Y B;  2MS7 A;  2VGQ A;  2N1F A;  2LS7 A;  2DBF A;  2N7Z A;  2XV9 A;  4M9Z A;  4O9F A;  3LQQ A;  3LQR A;  2YQF A;  4UZ0 A;  1DDF A;  2N80 A;  3CRD A;  3YGS P;  2LWD A;  4NQK A;  3YGS C;  1UCP A;  2BBR A;  2DBH A;  4EWI A;  1PN5 A;  3J63 A;  1CWW A;  4D8O A;  3CL3 A;  1Z6T A;  1YGO A;  2YU0 A;  1E3Y A; 
#chains in the Genus database with same CATH homology
 2MJM A;  4ZBW A;  4IZ7 B;  4O6X A;  4I16 A;  2NSN A;  2HM2 Q;  4P4H I;  4F42 A;  2MS8 A;  2M5V A;  1ICH A;  1E41 A;  4P4H A;  1NGR A;  4O9L A;  4N1J A;  2MN4 A;  2YVI A;  4IZA B;  2O71 A;  2DO9 A;  2NZ7 A;  4F44 A;  2B1W A;  1WXP A;  2YGS A;  4A2Q A;  1A1Z A;  4O7Q A;  4M9S A;  3EZQ B;  4JUP A;  2IB1 A;  4RHW A;  1WMG A;  4E9M A;  4N1L A;  2MB9 A;  3J6J A;  2DBD A;  2OF5 A;  2L6A A;  3MOP G;  2DBG A;  1D2Z B;  1C15 A;  2P1H A;  3EZQ A;  1A1W A;  3MOP A;  4JQW A;  1N3K A;  2A9I A;  4QOB A;  2BBZ A;  2N00 A;  4M9X A;  4FH0 A;  4N1K A;  1FAD A;  2OF5 H;  2KM6 A;  2MPC A;  3QF2 A;  1DGN A;  4RHW E;  2KN6 A;  1D2Z A;  2N83 A;  2LWE A;  1CY5 A;  4DWN A;  2GF5 A;  3T6P A;  3MOP K;  1WH4 A;  2N97 A;  4LWD A;  2L9M A;  4A2W A;  2F1S A;  2G7R A;  3KAT A;  2NAQ A;  2D96 A;  4IZ5 E;  2A5Y B;  2MS7 A;  2VGQ A;  2N1F A;  2LS7 A;  2DBF A;  2N7Z A;  2XV9 A;  4M9Z A;  4O9F A;  3LQQ A;  3LQR A;  2YQF A;  4UZ0 A;  1DDF A;  2N80 A;  3CRD A;  3YGS P;  2LWD A;  4NQK A;  3YGS C;  1UCP A;  2BBR A;  2DBH A;  4EWI A;  1PN5 A;  3J63 A;  1CWW A;  4D8O A;  3CL3 A;  1Z6T A;  1YGO A;  2YU0 A;  1E3Y A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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