2MS7A

High-resolution solid-state nmr structure of the helical signal transduction filament mavs card
Total Genus 26
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
26
sequence length
102
structure length
102
Chain Sequence
GSMPFAEDKTYKYICRNFSNFCNVDVVEILPYLPCLTARDQDRLRATCTLSGNRDTLWHLFNTLQRRPGWVEYFIAALRGCELVDLADEVASVYQSYQPRTS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Protein binding
source organism Homo sapiens
publication title Structure determination of helical filaments by solid-state NMR spectroscopy.
pubmed doi rcsb
molecule keywords Mitochondrial antiviral-signaling protein
total genus 26
structure length 102
sequence length 102
chains with identical sequence B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U
ec nomenclature
pdb deposition date 2014-07-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF16739 CARD_2 Caspase recruitment domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.533.10 Mainly Alpha Orthogonal Bundle Death Domain, Fas Death Domain, Fas 2ms7A00
2N7ZA 4N1JA 3KATA 4RHWA 3QF2A 1D2ZA 2LWDA 3LQQA 2D96A 3T6PA 4P4HI 4N1KA 4F44A 3MOPG 2YGSA 1FADA 4E9MA 4FH0A 3YGSP 4LWDA 4QOBA 1D2ZB 2P1HA 1CWWA 2DBHA 2MB9A 1C15A 4RHWE 1WH4A 2F1SA 1E41A 2NSNA 2DBDA 2YVIA 2O71A 2L6AA 2N80A 3J6JA 4JQWA 4JUPA 2MS8A 4DWNA 2KN6A 1ICHA 4A2QA 4O6XA 4I16A 2L9MA 2MPCA 4A2WA 2LWEA 1A1WA 2DO9A 2A9IA 2OF5A 4N1LA 2NZ7A 4M9SA 1N3KA 3CRDA 2YQFA 2DBGA 3MOPA 3CL3A 4M9XA 1WXPA 2N83A 2YU0A 1E3YA 2N00A 2MS7A 3EZQA 2B1WA 4D8OA 2KM6A 4IZAB 4F42A 2IB1A 1CY5A 2NAQA 3YGSC 4UZ0A 4O7QA 2HM2Q 4ZBWA 2DBFA 2BBZA 4NQKA 2M5VA 1Z6TA 2GF5A 3LQRA 1PN5A 3J63A 2A5YB 2OF5H 3EZQB 1A1ZA 3MOPK 4P4HA 1UCPA 4EWIA 4O9LA 4O9FA 1WMGA 4IZ5E 1YGOA 2N97A 2VGQA 1DGNA 2G7RA 2MN4A 4IZ7B 4M9ZA 2LS7A 2N1FA 1DDFA 1NGRA 2BBRA
chains in the Genus database with same CATH superfamily
2N7ZA 4N1JA 3KATA 4RHWA 3QF2A 1D2ZA 2LWDA 3LQQA 2D96A 3T6PA 4P4HI 4N1KA 4F44A 3MOPG 2YGSA 1FADA 4E9MA 4FH0A 3YGSP 4LWDA 4QOBA 1D2ZB 2XV9A 2P1HA 1CWWA 2DBHA 2MB9A 1C15A 4RHWE 1WH4A 2F1SA 1E41A 2NSNA 2DBDA 2YVIA 2O71A 2L6AA 2N80A 3J6JA 4JQWA 4JUPA 2MS8A 4DWNA 2KN6A 1ICHA 4A2QA 4O6XA 4I16A 2L9MA 2MPCA 4A2WA 2LWEA 1A1WA 2DO9A 2A9IA 2OF5A 4N1LA 2NZ7A 4M9SA 1N3KA 3CRDA 2YQFA 2DBGA 3MOPA 3CL3A 4M9XA 1WXPA 2N83A 2YU0A 1E3YA 2N00A 2MS7A 3EZQA 2B1WA 4D8OA 2KM6A 4IZAB 4F42A 2IB1A 1CY5A 2NAQA 3YGSC 4UZ0A 4O7QA 2HM2Q 4ZBWA 2DBFA 2BBZA 4NQKA 2M5VA 1Z6TA 2GF5A 3LQRA 1PN5A 3J63A 2A5YB 2OF5H 3EZQB 1A1ZA 3MOPK 4P4HA 1UCPA 4EWIA 4O9LA 4O9FA 1WMGA 4IZ5E 1YGOA 2N97A 2VGQA 1DGNA 2G7RA 2MN4A 2MJMA 4IZ7B 4M9ZA 2LS7A 2N1FA 1DDFA 1NGRA 2BBRA
chains in the Genus database with same CATH topology
2N7ZA 4N1JA 3KATA 4RHWA 3QF2A 1D2ZA 2LWDA 3LQQA 2D96A 3T6PA 4P4HI 4N1KA 4F44A 3MOPG 2YGSA 1FADA 4E9MA 4FH0A 3YGSP 4LWDA 4QOBA 1D2ZB 2XV9A 2P1HA 1CWWA 2DBHA 2MB9A 1C15A 4RHWE 1WH4A 2F1SA 1E41A 2NSNA 2DBDA 2YVIA 2O71A 2L6AA 2N80A 3J6JA 4JQWA 4JUPA 2MS8A 4DWNA 2KN6A 1ICHA 4A2QA 4O6XA 4I16A 2L9MA 2MPCA 4A2WA 2LWEA 1A1WA 2DO9A 2A9IA 2OF5A 4N1LA 2NZ7A 4M9SA 1N3KA 3CRDA 2YQFA 2DBGA 3MOPA 3CL3A 4M9XA 1WXPA 2N83A 2YU0A 1E3YA 2N00A 2MS7A 3EZQA 2B1WA 4D8OA 2KM6A 4IZAB 4F42A 2IB1A 1CY5A 2NAQA 3YGSC 4UZ0A 4O7QA 2HM2Q 4ZBWA 2DBFA 2BBZA 4NQKA 2M5VA 1Z6TA 2GF5A 3LQRA 1PN5A 3J63A 2A5YB 2OF5H 3EZQB 1A1ZA 3MOPK 4P4HA 1UCPA 4EWIA 4O9LA 4O9FA 1WMGA 4IZ5E 1YGOA 2N97A 2VGQA 1DGNA 2G7RA 2MN4A 2MJMA 4IZ7B 4M9ZA 2LS7A 2N1FA 1DDFA 1NGRA 2BBRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2N7Z A;  4N1J A;  3KAT A;  4RHW A;  3QF2 A;  1D2Z A;  2LWD A;  3LQQ A;  2D96 A;  3T6P A;  4P4H I;  4N1K A;  4F44 A;  3MOP G;  2YGS A;  1FAD A;  4E9M A;  4FH0 A;  3YGS P;  4LWD A;  4QOB A;  1D2Z B;  2P1H A;  1CWW A;  2DBH A;  2MB9 A;  1C15 A;  4RHW E;  1WH4 A;  2F1S A;  1E41 A;  2NSN A;  2DBD A;  2YVI A;  2O71 A;  2L6A A;  2N80 A;  3J6J A;  4JQW A;  4JUP A;  2MS8 A;  4DWN A;  2KN6 A;  1ICH A;  4A2Q A;  4O6X A;  4I16 A;  2L9M A;  2MPC A;  4A2W A;  2LWE A;  1A1W A;  2DO9 A;  2A9I A;  2OF5 A;  4N1L A;  2NZ7 A;  4M9S A;  1N3K A;  3CRD A;  2YQF A;  2DBG A;  3MOP A;  3CL3 A;  4M9X A;  1WXP A;  2N83 A;  2YU0 A;  1E3Y A;  2N00 A;  2MS7 A;  3EZQ A;  2B1W A;  4D8O A;  2KM6 A;  4IZA B;  4F42 A;  2IB1 A;  1CY5 A;  2NAQ A;  3YGS C;  4UZ0 A;  4O7Q A;  2HM2 Q;  4ZBW A;  2DBF A;  2BBZ A;  4NQK A;  2M5V A;  1Z6T A;  2GF5 A;  3LQR A;  1PN5 A;  3J63 A;  2A5Y B;  2OF5 H;  3EZQ B;  1A1Z A;  3MOP K;  4P4H A;  1UCP A;  4EWI A;  4O9L A;  4O9F A;  1WMG A;  4IZ5 E;  1YGO A;  2N97 A;  2VGQ A;  1DGN A;  2G7R A;  2MN4 A;  4IZ7 B;  4M9Z A;  2LS7 A;  2N1F A;  1DDF A;  1NGR A;  2BBR A; 
#chains in the Genus database with same CATH topology
 2N7Z A;  4N1J A;  3KAT A;  4RHW A;  3QF2 A;  1D2Z A;  2LWD A;  3LQQ A;  2D96 A;  3T6P A;  4P4H I;  4N1K A;  4F44 A;  3MOP G;  2YGS A;  1FAD A;  4E9M A;  4FH0 A;  3YGS P;  4LWD A;  4QOB A;  1D2Z B;  2XV9 A;  2P1H A;  1CWW A;  2DBH A;  2MB9 A;  1C15 A;  4RHW E;  1WH4 A;  2F1S A;  1E41 A;  2NSN A;  2DBD A;  2YVI A;  2O71 A;  2L6A A;  2N80 A;  3J6J A;  4JQW A;  4JUP A;  2MS8 A;  4DWN A;  2KN6 A;  1ICH A;  4A2Q A;  4O6X A;  4I16 A;  2L9M A;  2MPC A;  4A2W A;  2LWE A;  1A1W A;  2DO9 A;  2A9I A;  2OF5 A;  4N1L A;  2NZ7 A;  4M9S A;  1N3K A;  3CRD A;  2YQF A;  2DBG A;  3MOP A;  3CL3 A;  4M9X A;  1WXP A;  2N83 A;  2YU0 A;  1E3Y A;  2N00 A;  2MS7 A;  3EZQ A;  2B1W A;  4D8O A;  2KM6 A;  4IZA B;  4F42 A;  2IB1 A;  1CY5 A;  2NAQ A;  3YGS C;  4UZ0 A;  4O7Q A;  2HM2 Q;  4ZBW A;  2DBF A;  2BBZ A;  4NQK A;  2M5V A;  1Z6T A;  2GF5 A;  3LQR A;  1PN5 A;  3J63 A;  2A5Y B;  2OF5 H;  3EZQ B;  1A1Z A;  3MOP K;  4P4H A;  1UCP A;  4EWI A;  4O9L A;  4O9F A;  1WMG A;  4IZ5 E;  1YGO A;  2N97 A;  2VGQ A;  1DGN A;  2G7R A;  2MN4 A;  2MJM A;  4IZ7 B;  4M9Z A;  2LS7 A;  2N1F A;  1DDF A;  1NGR A;  2BBR A; 
#chains in the Genus database with same CATH homology
 2N7Z A;  4N1J A;  3KAT A;  4RHW A;  3QF2 A;  1D2Z A;  2LWD A;  3LQQ A;  2D96 A;  3T6P A;  4P4H I;  4N1K A;  4F44 A;  3MOP G;  2YGS A;  1FAD A;  4E9M A;  4FH0 A;  3YGS P;  4LWD A;  4QOB A;  1D2Z B;  2XV9 A;  2P1H A;  1CWW A;  2DBH A;  2MB9 A;  1C15 A;  4RHW E;  1WH4 A;  2F1S A;  1E41 A;  2NSN A;  2DBD A;  2YVI A;  2O71 A;  2L6A A;  2N80 A;  3J6J A;  4JQW A;  4JUP A;  2MS8 A;  4DWN A;  2KN6 A;  1ICH A;  4A2Q A;  4O6X A;  4I16 A;  2L9M A;  2MPC A;  4A2W A;  2LWE A;  1A1W A;  2DO9 A;  2A9I A;  2OF5 A;  4N1L A;  2NZ7 A;  4M9S A;  1N3K A;  3CRD A;  2YQF A;  2DBG A;  3MOP A;  3CL3 A;  4M9X A;  1WXP A;  2N83 A;  2YU0 A;  1E3Y A;  2N00 A;  2MS7 A;  3EZQ A;  2B1W A;  4D8O A;  2KM6 A;  4IZA B;  4F42 A;  2IB1 A;  1CY5 A;  2NAQ A;  3YGS C;  4UZ0 A;  4O7Q A;  2HM2 Q;  4ZBW A;  2DBF A;  2BBZ A;  4NQK A;  2M5V A;  1Z6T A;  2GF5 A;  3LQR A;  1PN5 A;  3J63 A;  2A5Y B;  2OF5 H;  3EZQ B;  1A1Z A;  3MOP K;  4P4H A;  1UCP A;  4EWI A;  4O9L A;  4O9F A;  1WMG A;  4IZ5 E;  1YGO A;  2N97 A;  2VGQ A;  1DGN A;  2G7R A;  2MN4 A;  2MJM A;  4IZ7 B;  4M9Z A;  2LS7 A;  2N1F A;  1DDF A;  1NGR A;  2BBR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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