2OF5H

Oligomeric death domain complex
Total Genus 32
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
32
sequence length
100
structure length
100
Chain Sequence
MNLGDAETGFLTQSNLLSVAGRLGLDWPAVALHLGVSYREVQRIRHEFRDDLDEQIRHMLFSWAERQAGQPGAVGLLVQALEQSDRQDVAEEVRAVLELG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Death domain assembly mechanism revealed by crystal structure of the oligomeric PIDDosome core complex.
pubmed doi rcsb
molecule tags Apoptosis
source organism Homo sapiens
molecule keywords Death domain-containing protein CRADD
total genus 32
structure length 100
sequence length 100
chains with identical sequence I, J, K, L
ec nomenclature
pdb deposition date 2007-01-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
H PF00531 Death Death domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.533.10 Mainly Alpha Orthogonal Bundle Death Domain, Fas Death Domain, Fas 2of5H00
3MOPK 4JUPA 4N1LA 4DWNA 4O7QA 4M9XA 4JQWA 1C15A 2M5VA 2YVIA 2G7RA 2BBZA 2YU0A 2LWEA 1FADA 2N7ZA 4N1KA 2LS7A 1DGNA 2L6AA 2MS8A 3KATA 1UCPA 2A5YB 3YGSP 1D2ZA 2MPCA 4LWDA 2BBRA 4F42A 2N80A 2DBFA 2YQFA 2OF5H 4P4HI 4ZBWA 4A2WA 2KM6A 2N97A 1N3KA 2L9MA 2D96A 1WMGA 4RHWE 2N83A 1Z6TA 2DO9A 4FH0A 1NGRA 2DBHA 4UZ0A 2N00A 2O71A 1PN5A 2DBDA 3MOPA 4IZ7B 4RHWA 4N1JA 3T6PA 3CL3A 4E9MA 4D8OA 1WXPA 4O9LA 2LWDA 1A1ZA 1A1WA 1CY5A 3LQQA 2YGSA 4A2QA 3EZQB 2A9IA 3LQRA 4IZAB 2KN6A 2NSNA 2F1SA 1E3YA 4IZ5E 2GF5A 3J63A 3YGSC 4F44A 4I16A 4M9SA 2MB9A 1CWWA 2IB1A 2MS7A 3MOPG 1E41A 2N1FA 2NAQA 3QF2A 1ICHA 2B1WA 4O9FA 1WH4A 2P1HA 3EZQA 2HM2Q 1YGOA 4EWIA 4M9ZA 4P4HA 2NZ7A 2MN4A 2DBGA 4QOBA 4NQKA 1DDFA 3CRDA 2OF5A 1D2ZB 4O6XA 3J6JA 2VGQA
chains in the Genus database with same CATH superfamily
3MOPK 4JUPA 4N1LA 4DWNA 4O7QA 4M9XA 4JQWA 1C15A 2M5VA 2YVIA 2G7RA 2BBZA 2YU0A 2LWEA 1FADA 2N7ZA 4N1KA 2LS7A 1DGNA 2L6AA 2MS8A 3KATA 1UCPA 2A5YB 3YGSP 1D2ZA 2MPCA 4LWDA 2BBRA 4F42A 2N80A 2DBFA 2YQFA 2OF5H 4P4HI 4ZBWA 4A2WA 2KM6A 2N97A 1N3KA 2L9MA 2D96A 1WMGA 4RHWE 2N83A 1Z6TA 2DO9A 4FH0A 1NGRA 2DBHA 4UZ0A 2N00A 2O71A 1PN5A 2DBDA 2XV9A 3MOPA 4IZ7B 4RHWA 4N1JA 3T6PA 3CL3A 4E9MA 4D8OA 1WXPA 4O9LA 2LWDA 1A1ZA 1A1WA 1CY5A 3LQQA 2YGSA 4A2QA 3EZQB 2A9IA 3LQRA 4IZAB 2KN6A 2NSNA 2F1SA 1E3YA 4IZ5E 2GF5A 3J63A 3YGSC 4F44A 4I16A 4M9SA 2MB9A 1CWWA 2IB1A 2MS7A 3MOPG 1E41A 2N1FA 2NAQA 3QF2A 1ICHA 2B1WA 4O9FA 1WH4A 2P1HA 3EZQA 2HM2Q 2MJMA 1YGOA 4EWIA 4M9ZA 4P4HA 2NZ7A 2MN4A 2DBGA 4QOBA 4NQKA 1DDFA 3CRDA 2OF5A 1D2ZB 4O6XA 3J6JA 2VGQA
chains in the Genus database with same CATH topology
3MOPK 4JUPA 4N1LA 4DWNA 4O7QA 4M9XA 4JQWA 1C15A 2M5VA 2YVIA 2G7RA 2BBZA 2YU0A 2LWEA 1FADA 2N7ZA 4N1KA 2LS7A 1DGNA 2L6AA 2MS8A 3KATA 1UCPA 2A5YB 3YGSP 1D2ZA 2MPCA 4LWDA 2BBRA 4F42A 2N80A 2DBFA 2YQFA 2OF5H 4P4HI 4ZBWA 4A2WA 2KM6A 2N97A 1N3KA 2L9MA 2D96A 1WMGA 4RHWE 2N83A 1Z6TA 2DO9A 4FH0A 1NGRA 2DBHA 4UZ0A 2N00A 2O71A 1PN5A 2DBDA 2XV9A 3MOPA 4IZ7B 4RHWA 4N1JA 3T6PA 3CL3A 4E9MA 4D8OA 1WXPA 4O9LA 2LWDA 1A1ZA 1A1WA 1CY5A 3LQQA 2YGSA 4A2QA 3EZQB 2A9IA 3LQRA 4IZAB 2KN6A 2NSNA 2F1SA 1E3YA 4IZ5E 2GF5A 3J63A 3YGSC 4F44A 4I16A 4M9SA 2MB9A 1CWWA 2IB1A 2MS7A 3MOPG 1E41A 2N1FA 2NAQA 3QF2A 1ICHA 2B1WA 4O9FA 1WH4A 2P1HA 3EZQA 2HM2Q 2MJMA 1YGOA 4EWIA 4M9ZA 4P4HA 2NZ7A 2MN4A 2DBGA 4QOBA 4NQKA 1DDFA 3CRDA 2OF5A 1D2ZB 4O6XA 3J6JA 2VGQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3MOP K;  4JUP A;  4N1L A;  4DWN A;  4O7Q A;  4M9X A;  4JQW A;  1C15 A;  2M5V A;  2YVI A;  2G7R A;  2BBZ A;  2YU0 A;  2LWE A;  1FAD A;  2N7Z A;  4N1K A;  2LS7 A;  1DGN A;  2L6A A;  2MS8 A;  3KAT A;  1UCP A;  2A5Y B;  3YGS P;  1D2Z A;  2MPC A;  4LWD A;  2BBR A;  4F42 A;  2N80 A;  2DBF A;  2YQF A;  2OF5 H;  4P4H I;  4ZBW A;  4A2W A;  2KM6 A;  2N97 A;  1N3K A;  2L9M A;  2D96 A;  1WMG A;  4RHW E;  2N83 A;  1Z6T A;  2DO9 A;  4FH0 A;  1NGR A;  2DBH A;  4UZ0 A;  2N00 A;  2O71 A;  1PN5 A;  2DBD A;  3MOP A;  4IZ7 B;  4RHW A;  4N1J A;  3T6P A;  3CL3 A;  4E9M A;  4D8O A;  1WXP A;  4O9L A;  2LWD A;  1A1Z A;  1A1W A;  1CY5 A;  3LQQ A;  2YGS A;  4A2Q A;  3EZQ B;  2A9I A;  3LQR A;  4IZA B;  2KN6 A;  2NSN A;  2F1S A;  1E3Y A;  4IZ5 E;  2GF5 A;  3J63 A;  3YGS C;  4F44 A;  4I16 A;  4M9S A;  2MB9 A;  1CWW A;  2IB1 A;  2MS7 A;  3MOP G;  1E41 A;  2N1F A;  2NAQ A;  3QF2 A;  1ICH A;  2B1W A;  4O9F A;  1WH4 A;  2P1H A;  3EZQ A;  2HM2 Q;  1YGO A;  4EWI A;  4M9Z A;  4P4H A;  2NZ7 A;  2MN4 A;  2DBG A;  4QOB A;  4NQK A;  1DDF A;  3CRD A;  2OF5 A;  1D2Z B;  4O6X A;  3J6J A;  2VGQ A; 
#chains in the Genus database with same CATH topology
 3MOP K;  4JUP A;  4N1L A;  4DWN A;  4O7Q A;  4M9X A;  4JQW A;  1C15 A;  2M5V A;  2YVI A;  2G7R A;  2BBZ A;  2YU0 A;  2LWE A;  1FAD A;  2N7Z A;  4N1K A;  2LS7 A;  1DGN A;  2L6A A;  2MS8 A;  3KAT A;  1UCP A;  2A5Y B;  3YGS P;  1D2Z A;  2MPC A;  4LWD A;  2BBR A;  4F42 A;  2N80 A;  2DBF A;  2YQF A;  2OF5 H;  4P4H I;  4ZBW A;  4A2W A;  2KM6 A;  2N97 A;  1N3K A;  2L9M A;  2D96 A;  1WMG A;  4RHW E;  2N83 A;  1Z6T A;  2DO9 A;  4FH0 A;  1NGR A;  2DBH A;  4UZ0 A;  2N00 A;  2O71 A;  1PN5 A;  2DBD A;  2XV9 A;  3MOP A;  4IZ7 B;  4RHW A;  4N1J A;  3T6P A;  3CL3 A;  4E9M A;  4D8O A;  1WXP A;  4O9L A;  2LWD A;  1A1Z A;  1A1W A;  1CY5 A;  3LQQ A;  2YGS A;  4A2Q A;  3EZQ B;  2A9I A;  3LQR A;  4IZA B;  2KN6 A;  2NSN A;  2F1S A;  1E3Y A;  4IZ5 E;  2GF5 A;  3J63 A;  3YGS C;  4F44 A;  4I16 A;  4M9S A;  2MB9 A;  1CWW A;  2IB1 A;  2MS7 A;  3MOP G;  1E41 A;  2N1F A;  2NAQ A;  3QF2 A;  1ICH A;  2B1W A;  4O9F A;  1WH4 A;  2P1H A;  3EZQ A;  2HM2 Q;  2MJM A;  1YGO A;  4EWI A;  4M9Z A;  4P4H A;  2NZ7 A;  2MN4 A;  2DBG A;  4QOB A;  4NQK A;  1DDF A;  3CRD A;  2OF5 A;  1D2Z B;  4O6X A;  3J6J A;  2VGQ A; 
#chains in the Genus database with same CATH homology
 3MOP K;  4JUP A;  4N1L A;  4DWN A;  4O7Q A;  4M9X A;  4JQW A;  1C15 A;  2M5V A;  2YVI A;  2G7R A;  2BBZ A;  2YU0 A;  2LWE A;  1FAD A;  2N7Z A;  4N1K A;  2LS7 A;  1DGN A;  2L6A A;  2MS8 A;  3KAT A;  1UCP A;  2A5Y B;  3YGS P;  1D2Z A;  2MPC A;  4LWD A;  2BBR A;  4F42 A;  2N80 A;  2DBF A;  2YQF A;  2OF5 H;  4P4H I;  4ZBW A;  4A2W A;  2KM6 A;  2N97 A;  1N3K A;  2L9M A;  2D96 A;  1WMG A;  4RHW E;  2N83 A;  1Z6T A;  2DO9 A;  4FH0 A;  1NGR A;  2DBH A;  4UZ0 A;  2N00 A;  2O71 A;  1PN5 A;  2DBD A;  2XV9 A;  3MOP A;  4IZ7 B;  4RHW A;  4N1J A;  3T6P A;  3CL3 A;  4E9M A;  4D8O A;  1WXP A;  4O9L A;  2LWD A;  1A1Z A;  1A1W A;  1CY5 A;  3LQQ A;  2YGS A;  4A2Q A;  3EZQ B;  2A9I A;  3LQR A;  4IZA B;  2KN6 A;  2NSN A;  2F1S A;  1E3Y A;  4IZ5 E;  2GF5 A;  3J63 A;  3YGS C;  4F44 A;  4I16 A;  4M9S A;  2MB9 A;  1CWW A;  2IB1 A;  2MS7 A;  3MOP G;  1E41 A;  2N1F A;  2NAQ A;  3QF2 A;  1ICH A;  2B1W A;  4O9F A;  1WH4 A;  2P1H A;  3EZQ A;  2HM2 Q;  2MJM A;  1YGO A;  4EWI A;  4M9Z A;  4P4H A;  2NZ7 A;  2MN4 A;  2DBG A;  4QOB A;  4NQK A;  1DDF A;  3CRD A;  2OF5 A;  1D2Z B;  4O6X A;  3J6J A;  2VGQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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