2OF5H

Oligomeric death domain complex
Total Genus 32
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
32
sequence length
100
structure length
100
Chain Sequence
MNLGDAETGFLTQSNLLSVAGRLGLDWPAVALHLGVSYREVQRIRHEFRDDLDEQIRHMLFSWAERQAGQPGAVGLLVQALEQSDRQDVAEEVRAVLELG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
publication title Death domain assembly mechanism revealed by crystal structure of the oligomeric PIDDosome core complex.
pubmed doi rcsb
molecule tags Apoptosis
source organism Homo sapiens
molecule keywords Death domain-containing protein CRADD
total genus 32
structure length 100
sequence length 100
chains with identical sequence I, J, K, L
ec nomenclature
pdb deposition date 2007-01-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
H PF00531 Death Death domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.533.10 Mainly Alpha Orthogonal Bundle Death Domain, Fas Death Domain, Fas 2of5H00
3MOPA 4F42A 2MN4A 4RHWE 3LQRA 2MPCA 1WMGA 1E3YA 2N97A 2O71A 3MOPG 1WH4A 1A1WA 2LWDA 2KM6A 3CRDA 2P1HA 3CL3A 2YU0A 2OF5H 2LS7A 3J63A 2DBFA 3EZQB 3MOPK 2D96A 2DBHA 2N7ZA 4O9FA 4F44A 2L6AA 4A2QA 2YVIA 2MS8A 2YGSA 4N1LA 1DDFA 1D2ZA 3LQQA 3T6PA 4N1JA 1CWWA 2MB9A 2LWEA 1ICHA 2BBRA 4EWIA 1YGOA 2YQFA 2N83A 4O7QA 4IZ7B 2HM2Q 4ZBWA 1FADA 4O9LA 1Z6TA 4JQWA 4N1KA 2NZ7A 4M9SA 4JUPA 2B1WA 4IZAB 2A9IA 1UCPA 2VGQA 2N1FA 1N3KA 1D2ZB 4A2WA 1WXPA 4M9ZA 3EZQA 1CY5A 2N80A 2IB1A 2L9MA 2NAQA 4FH0A 4LWDA 2DBGA 1C15A 2N00A 2DBDA 3KATA 4DWNA 1NGRA 4I16A 3QF2A 1E41A 4NQKA 2GF5A 4P4HA 4D8OA 2DO9A 1PN5A 2KN6A 4E9MA 2BBZA 2OF5A 4O6XA 4QOBA 3YGSP 4M9XA 4P4HI 2A5YB 4RHWA 2NSNA 1A1ZA 2F1SA 1DGNA 2M5VA 4IZ5E 4UZ0A 2MS7A 3J6JA 2G7RA 3YGSC
chains in the Genus database with same CATH superfamily
3MOPA 4F42A 2MN4A 4RHWE 3LQRA 2MPCA 1WMGA 1E3YA 2N97A 2O71A 3MOPG 1WH4A 1A1WA 2MJMA 2LWDA 2KM6A 3CRDA 2P1HA 3CL3A 2YU0A 2OF5H 2LS7A 3J63A 2DBFA 3EZQB 3MOPK 2D96A 2DBHA 2N7ZA 4O9FA 4F44A 2L6AA 4A2QA 2YVIA 2MS8A 2YGSA 4N1LA 1DDFA 1D2ZA 3LQQA 3T6PA 4N1JA 1CWWA 2MB9A 2LWEA 1ICHA 2BBRA 4EWIA 1YGOA 2YQFA 2N83A 4O7QA 4IZ7B 2HM2Q 4ZBWA 1FADA 4O9LA 1Z6TA 4JQWA 4N1KA 2NZ7A 4M9SA 4JUPA 2B1WA 4IZAB 2A9IA 1UCPA 2VGQA 2N1FA 1N3KA 1D2ZB 4A2WA 1WXPA 4M9ZA 3EZQA 1CY5A 2N80A 2IB1A 2L9MA 2NAQA 4FH0A 4LWDA 2DBGA 1C15A 2N00A 2DBDA 3KATA 4DWNA 1NGRA 4I16A 3QF2A 1E41A 2XV9A 2GF5A 4NQKA 4P4HA 4D8OA 2DO9A 1PN5A 2KN6A 4E9MA 2BBZA 2OF5A 4O6XA 4QOBA 3YGSP 4M9XA 4P4HI 2A5YB 4RHWA 2NSNA 1A1ZA 2F1SA 1DGNA 2M5VA 4IZ5E 4UZ0A 2MS7A 3J6JA 2G7RA 3YGSC
chains in the Genus database with same CATH topology
3MOPA 4F42A 2MN4A 4RHWE 3LQRA 2MPCA 1WMGA 1E3YA 2N97A 2O71A 3MOPG 1WH4A 1A1WA 2MJMA 2LWDA 2KM6A 3CRDA 2P1HA 3CL3A 2YU0A 2OF5H 2LS7A 3J63A 2DBFA 3EZQB 3MOPK 2D96A 2DBHA 2N7ZA 4O9FA 4F44A 2L6AA 4A2QA 2YVIA 2MS8A 2YGSA 4N1LA 1DDFA 1D2ZA 3LQQA 3T6PA 4N1JA 1CWWA 2MB9A 2LWEA 1ICHA 2BBRA 4EWIA 1YGOA 2YQFA 2N83A 4O7QA 4IZ7B 2HM2Q 4ZBWA 1FADA 4O9LA 1Z6TA 4JQWA 4N1KA 2NZ7A 4M9SA 4JUPA 2B1WA 4IZAB 2A9IA 1UCPA 2VGQA 2N1FA 1N3KA 1D2ZB 4A2WA 1WXPA 4M9ZA 3EZQA 1CY5A 2N80A 2IB1A 2L9MA 2NAQA 4FH0A 4LWDA 2DBGA 1C15A 2N00A 2DBDA 3KATA 4DWNA 1NGRA 4I16A 3QF2A 1E41A 2XV9A 2GF5A 4NQKA 4P4HA 4D8OA 2DO9A 1PN5A 2KN6A 4E9MA 2BBZA 2OF5A 4O6XA 4QOBA 3YGSP 4M9XA 4P4HI 2A5YB 4RHWA 2NSNA 1A1ZA 2F1SA 1DGNA 2M5VA 4IZ5E 4UZ0A 2MS7A 3J6JA 2G7RA 3YGSC
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 3MOP A;  4F42 A;  2MN4 A;  4RHW E;  3LQR A;  2MPC A;  1WMG A;  1E3Y A;  2N97 A;  2O71 A;  3MOP G;  1WH4 A;  1A1W A;  2LWD A;  2KM6 A;  3CRD A;  2P1H A;  3CL3 A;  2YU0 A;  2OF5 H;  2LS7 A;  3J63 A;  2DBF A;  3EZQ B;  3MOP K;  2D96 A;  2DBH A;  2N7Z A;  4O9F A;  4F44 A;  2L6A A;  4A2Q A;  2YVI A;  2MS8 A;  2YGS A;  4N1L A;  1DDF A;  1D2Z A;  3LQQ A;  3T6P A;  4N1J A;  1CWW A;  2MB9 A;  2LWE A;  1ICH A;  2BBR A;  4EWI A;  1YGO A;  2YQF A;  2N83 A;  4O7Q A;  4IZ7 B;  2HM2 Q;  4ZBW A;  1FAD A;  4O9L A;  1Z6T A;  4JQW A;  4N1K A;  2NZ7 A;  4M9S A;  4JUP A;  2B1W A;  4IZA B;  2A9I A;  1UCP A;  2VGQ A;  2N1F A;  1N3K A;  1D2Z B;  4A2W A;  1WXP A;  4M9Z A;  3EZQ A;  1CY5 A;  2N80 A;  2IB1 A;  2L9M A;  2NAQ A;  4FH0 A;  4LWD A;  2DBG A;  1C15 A;  2N00 A;  2DBD A;  3KAT A;  4DWN A;  1NGR A;  4I16 A;  3QF2 A;  1E41 A;  4NQK A;  2GF5 A;  4P4H A;  4D8O A;  2DO9 A;  1PN5 A;  2KN6 A;  4E9M A;  2BBZ A;  2OF5 A;  4O6X A;  4QOB A;  3YGS P;  4M9X A;  4P4H I;  2A5Y B;  4RHW A;  2NSN A;  1A1Z A;  2F1S A;  1DGN A;  2M5V A;  4IZ5 E;  4UZ0 A;  2MS7 A;  3J6J A;  2G7R A;  3YGS C; 
#chains in the Genus database with same CATH topology
 3MOP A;  4F42 A;  2MN4 A;  4RHW E;  3LQR A;  2MPC A;  1WMG A;  1E3Y A;  2N97 A;  2O71 A;  3MOP G;  1WH4 A;  1A1W A;  2MJM A;  2LWD A;  2KM6 A;  3CRD A;  2P1H A;  3CL3 A;  2YU0 A;  2OF5 H;  2LS7 A;  3J63 A;  2DBF A;  3EZQ B;  3MOP K;  2D96 A;  2DBH A;  2N7Z A;  4O9F A;  4F44 A;  2L6A A;  4A2Q A;  2YVI A;  2MS8 A;  2YGS A;  4N1L A;  1DDF A;  1D2Z A;  3LQQ A;  3T6P A;  4N1J A;  1CWW A;  2MB9 A;  2LWE A;  1ICH A;  2BBR A;  4EWI A;  1YGO A;  2YQF A;  2N83 A;  4O7Q A;  4IZ7 B;  2HM2 Q;  4ZBW A;  1FAD A;  4O9L A;  1Z6T A;  4JQW A;  4N1K A;  2NZ7 A;  4M9S A;  4JUP A;  2B1W A;  4IZA B;  2A9I A;  1UCP A;  2VGQ A;  2N1F A;  1N3K A;  1D2Z B;  4A2W A;  1WXP A;  4M9Z A;  3EZQ A;  1CY5 A;  2N80 A;  2IB1 A;  2L9M A;  2NAQ A;  4FH0 A;  4LWD A;  2DBG A;  1C15 A;  2N00 A;  2DBD A;  3KAT A;  4DWN A;  1NGR A;  4I16 A;  3QF2 A;  1E41 A;  2XV9 A;  2GF5 A;  4NQK A;  4P4H A;  4D8O A;  2DO9 A;  1PN5 A;  2KN6 A;  4E9M A;  2BBZ A;  2OF5 A;  4O6X A;  4QOB A;  3YGS P;  4M9X A;  4P4H I;  2A5Y B;  4RHW A;  2NSN A;  1A1Z A;  2F1S A;  1DGN A;  2M5V A;  4IZ5 E;  4UZ0 A;  2MS7 A;  3J6J A;  2G7R A;  3YGS C; 
#chains in the Genus database with same CATH homology
 3MOP A;  4F42 A;  2MN4 A;  4RHW E;  3LQR A;  2MPC A;  1WMG A;  1E3Y A;  2N97 A;  2O71 A;  3MOP G;  1WH4 A;  1A1W A;  2MJM A;  2LWD A;  2KM6 A;  3CRD A;  2P1H A;  3CL3 A;  2YU0 A;  2OF5 H;  2LS7 A;  3J63 A;  2DBF A;  3EZQ B;  3MOP K;  2D96 A;  2DBH A;  2N7Z A;  4O9F A;  4F44 A;  2L6A A;  4A2Q A;  2YVI A;  2MS8 A;  2YGS A;  4N1L A;  1DDF A;  1D2Z A;  3LQQ A;  3T6P A;  4N1J A;  1CWW A;  2MB9 A;  2LWE A;  1ICH A;  2BBR A;  4EWI A;  1YGO A;  2YQF A;  2N83 A;  4O7Q A;  4IZ7 B;  2HM2 Q;  4ZBW A;  1FAD A;  4O9L A;  1Z6T A;  4JQW A;  4N1K A;  2NZ7 A;  4M9S A;  4JUP A;  2B1W A;  4IZA B;  2A9I A;  1UCP A;  2VGQ A;  2N1F A;  1N3K A;  1D2Z B;  4A2W A;  1WXP A;  4M9Z A;  3EZQ A;  1CY5 A;  2N80 A;  2IB1 A;  2L9M A;  2NAQ A;  4FH0 A;  4LWD A;  2DBG A;  1C15 A;  2N00 A;  2DBD A;  3KAT A;  4DWN A;  1NGR A;  4I16 A;  3QF2 A;  1E41 A;  2XV9 A;  2GF5 A;  4NQK A;  4P4H A;  4D8O A;  2DO9 A;  1PN5 A;  2KN6 A;  4E9M A;  2BBZ A;  2OF5 A;  4O6X A;  4QOB A;  3YGS P;  4M9X A;  4P4H I;  2A5Y B;  4RHW A;  2NSN A;  1A1Z A;  2F1S A;  1DGN A;  2M5V A;  4IZ5 E;  4UZ0 A;  2MS7 A;  3J6J A;  2G7R A;  3YGS C;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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