2P1HA

Rapid folding and unfolding of apaf-1 card
Total Genus 34
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
34
sequence length
94
structure length
94
Chain Sequence
GSMDAKARNCLLQHREALEKDIKTSYIMDHMISDGFLTISEEEKVRNEPTQQQRAAMLIKMILKKDNDSYVSFYNALLHEGYKDLAALLHDGIP
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule tags Apoptosis
source organism Homo sapiens
publication title Rapid Folding and Unfolding of Apaf-1 CARD.
pubmed doi rcsb
molecule keywords Apoptotic protease-activating factor 1
total genus 34
structure length 94
sequence length 94
ec nomenclature
pdb deposition date 2007-03-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00619 CARD Caspase recruitment domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.533.10 Mainly Alpha Orthogonal Bundle Death Domain, Fas Death Domain, Fas 2p1hA00
2MB9A 3YGSC 1CWWA 4IZAB 1NGRA 2DBGA 2GF5A 2N1FA 1WXPA 2IB1A 2YGSA 4EWIA 1DGNA 3MOPA 4M9SA 1D2ZA 2MS7A 2BBZA 1C15A 4LWDA 1WH4A 3EZQA 2NSNA 4DWNA 4ZBWA 2N97A 4D8OA 2G7RA 1D2ZB 2KM6A 2O71A 2N7ZA 2YVIA 4O7QA 1CY5A 4NQKA 2L6AA 2HM2Q 2D96A 4F42A 2OF5A 2MN4A 4A2WA 2N83A 4QOBA 4I16A 1E41A 2M5VA 2N80A 1E3YA 2L9MA 3LQRA 4F44A 4M9XA 2YQFA 2MS8A 2NZ7A 3MOPK 2DO9A 4N1KA 1FADA 2LS7A 4E9MA 4UZ0A 1YGOA 4P4HI 2VGQA 4JUPA 1WMGA 3J63A 4P4HA 2KN6A 4O9LA 3YGSP 3J6JA 1N3KA 1ICHA 4FH0A 3T6PA 3EZQB 2YU0A 1A1ZA 2NAQA 4M9ZA 2DBDA 3MOPG 2N00A 4O6XA 1A1WA 3KATA 3CL3A 4RHWE 2DBHA 2LWDA 4N1LA 4IZ7B 1DDFA 4RHWA 3LQQA 4A2QA 2OF5H 2BBRA 4IZ5E 2P1HA 2A9IA 4O9FA 3CRDA 2B1WA 3QF2A 1UCPA 2A5YB 2MPCA 4JQWA 1Z6TA 1PN5A 4N1JA 2F1SA 2LWEA 2DBFA
chains in the Genus database with same CATH superfamily
2MB9A 3YGSC 1CWWA 4IZAB 1NGRA 2DBGA 2GF5A 2N1FA 1WXPA 2IB1A 2YGSA 4EWIA 1DGNA 3MOPA 4M9SA 1D2ZA 2MS7A 2BBZA 1C15A 4LWDA 1WH4A 2MJMA 3EZQA 2NSNA 4DWNA 4ZBWA 2N97A 4D8OA 2G7RA 1D2ZB 2KM6A 2O71A 2N7ZA 2YVIA 4O7QA 1CY5A 4NQKA 2L6AA 2HM2Q 2D96A 4F42A 2OF5A 2MN4A 4A2WA 2N83A 4QOBA 4I16A 1E41A 2M5VA 2N80A 1E3YA 2L9MA 3LQRA 4F44A 4M9XA 2YQFA 2MS8A 2NZ7A 3MOPK 2DO9A 4N1KA 1FADA 2LS7A 4E9MA 4UZ0A 1YGOA 4P4HI 2VGQA 4JUPA 1WMGA 3J63A 4P4HA 2KN6A 4O9LA 3YGSP 3J6JA 1N3KA 1ICHA 4FH0A 3T6PA 3EZQB 2YU0A 1A1ZA 2NAQA 4M9ZA 2DBDA 3MOPG 2N00A 4O6XA 1A1WA 3KATA 2XV9A 3CL3A 4RHWE 2DBHA 2LWDA 4N1LA 4IZ7B 1DDFA 4RHWA 3LQQA 4A2QA 2OF5H 2BBRA 4IZ5E 2P1HA 2A9IA 4O9FA 3CRDA 2B1WA 3QF2A 1UCPA 2A5YB 2MPCA 4JQWA 1Z6TA 1PN5A 4N1JA 2F1SA 2LWEA 2DBFA
chains in the Genus database with same CATH topology
2MB9A 3YGSC 1CWWA 4IZAB 1NGRA 2DBGA 2GF5A 2N1FA 1WXPA 2IB1A 2YGSA 4EWIA 1DGNA 3MOPA 4M9SA 1D2ZA 2MS7A 2BBZA 1C15A 4LWDA 1WH4A 2MJMA 3EZQA 2NSNA 4DWNA 4ZBWA 2N97A 4D8OA 2G7RA 1D2ZB 2KM6A 2O71A 2N7ZA 2YVIA 4O7QA 1CY5A 4NQKA 2L6AA 2HM2Q 2D96A 4F42A 2OF5A 2MN4A 4A2WA 2N83A 4QOBA 4I16A 1E41A 2M5VA 2N80A 1E3YA 2L9MA 3LQRA 4F44A 4M9XA 2YQFA 2MS8A 2NZ7A 3MOPK 2DO9A 4N1KA 1FADA 2LS7A 4E9MA 4UZ0A 1YGOA 4P4HI 2VGQA 4JUPA 1WMGA 3J63A 4P4HA 2KN6A 4O9LA 3YGSP 3J6JA 1N3KA 1ICHA 4FH0A 3T6PA 3EZQB 2YU0A 1A1ZA 2NAQA 4M9ZA 2DBDA 3MOPG 2N00A 4O6XA 1A1WA 3KATA 2XV9A 3CL3A 4RHWE 2DBHA 2LWDA 4N1LA 4IZ7B 1DDFA 4RHWA 3LQQA 4A2QA 2OF5H 2BBRA 4IZ5E 2P1HA 2A9IA 4O9FA 3CRDA 2B1WA 3QF2A 1UCPA 2A5YB 2MPCA 4JQWA 1Z6TA 1PN5A 4N1JA 2F1SA 2LWEA 2DBFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2MB9 A;  3YGS C;  1CWW A;  4IZA B;  1NGR A;  2DBG A;  2GF5 A;  2N1F A;  1WXP A;  2IB1 A;  2YGS A;  4EWI A;  1DGN A;  3MOP A;  4M9S A;  1D2Z A;  2MS7 A;  2BBZ A;  1C15 A;  4LWD A;  1WH4 A;  3EZQ A;  2NSN A;  4DWN A;  4ZBW A;  2N97 A;  4D8O A;  2G7R A;  1D2Z B;  2KM6 A;  2O71 A;  2N7Z A;  2YVI A;  4O7Q A;  1CY5 A;  4NQK A;  2L6A A;  2HM2 Q;  2D96 A;  4F42 A;  2OF5 A;  2MN4 A;  4A2W A;  2N83 A;  4QOB A;  4I16 A;  1E41 A;  2M5V A;  2N80 A;  1E3Y A;  2L9M A;  3LQR A;  4F44 A;  4M9X A;  2YQF A;  2MS8 A;  2NZ7 A;  3MOP K;  2DO9 A;  4N1K A;  1FAD A;  2LS7 A;  4E9M A;  4UZ0 A;  1YGO A;  4P4H I;  2VGQ A;  4JUP A;  1WMG A;  3J63 A;  4P4H A;  2KN6 A;  4O9L A;  3YGS P;  3J6J A;  1N3K A;  1ICH A;  4FH0 A;  3T6P A;  3EZQ B;  2YU0 A;  1A1Z A;  2NAQ A;  4M9Z A;  2DBD A;  3MOP G;  2N00 A;  4O6X A;  1A1W A;  3KAT A;  3CL3 A;  4RHW E;  2DBH A;  2LWD A;  4N1L A;  4IZ7 B;  1DDF A;  4RHW A;  3LQQ A;  4A2Q A;  2OF5 H;  2BBR A;  4IZ5 E;  2P1H A;  2A9I A;  4O9F A;  3CRD A;  2B1W A;  3QF2 A;  1UCP A;  2A5Y B;  2MPC A;  4JQW A;  1Z6T A;  1PN5 A;  4N1J A;  2F1S A;  2LWE A;  2DBF A; 
#chains in the Genus database with same CATH topology
 2MB9 A;  3YGS C;  1CWW A;  4IZA B;  1NGR A;  2DBG A;  2GF5 A;  2N1F A;  1WXP A;  2IB1 A;  2YGS A;  4EWI A;  1DGN A;  3MOP A;  4M9S A;  1D2Z A;  2MS7 A;  2BBZ A;  1C15 A;  4LWD A;  1WH4 A;  2MJM A;  3EZQ A;  2NSN A;  4DWN A;  4ZBW A;  2N97 A;  4D8O A;  2G7R A;  1D2Z B;  2KM6 A;  2O71 A;  2N7Z A;  2YVI A;  4O7Q A;  1CY5 A;  4NQK A;  2L6A A;  2HM2 Q;  2D96 A;  4F42 A;  2OF5 A;  2MN4 A;  4A2W A;  2N83 A;  4QOB A;  4I16 A;  1E41 A;  2M5V A;  2N80 A;  1E3Y A;  2L9M A;  3LQR A;  4F44 A;  4M9X A;  2YQF A;  2MS8 A;  2NZ7 A;  3MOP K;  2DO9 A;  4N1K A;  1FAD A;  2LS7 A;  4E9M A;  4UZ0 A;  1YGO A;  4P4H I;  2VGQ A;  4JUP A;  1WMG A;  3J63 A;  4P4H A;  2KN6 A;  4O9L A;  3YGS P;  3J6J A;  1N3K A;  1ICH A;  4FH0 A;  3T6P A;  3EZQ B;  2YU0 A;  1A1Z A;  2NAQ A;  4M9Z A;  2DBD A;  3MOP G;  2N00 A;  4O6X A;  1A1W A;  3KAT A;  2XV9 A;  3CL3 A;  4RHW E;  2DBH A;  2LWD A;  4N1L A;  4IZ7 B;  1DDF A;  4RHW A;  3LQQ A;  4A2Q A;  2OF5 H;  2BBR A;  4IZ5 E;  2P1H A;  2A9I A;  4O9F A;  3CRD A;  2B1W A;  3QF2 A;  1UCP A;  2A5Y B;  2MPC A;  4JQW A;  1Z6T A;  1PN5 A;  4N1J A;  2F1S A;  2LWE A;  2DBF A; 
#chains in the Genus database with same CATH homology
 2MB9 A;  3YGS C;  1CWW A;  4IZA B;  1NGR A;  2DBG A;  2GF5 A;  2N1F A;  1WXP A;  2IB1 A;  2YGS A;  4EWI A;  1DGN A;  3MOP A;  4M9S A;  1D2Z A;  2MS7 A;  2BBZ A;  1C15 A;  4LWD A;  1WH4 A;  2MJM A;  3EZQ A;  2NSN A;  4DWN A;  4ZBW A;  2N97 A;  4D8O A;  2G7R A;  1D2Z B;  2KM6 A;  2O71 A;  2N7Z A;  2YVI A;  4O7Q A;  1CY5 A;  4NQK A;  2L6A A;  2HM2 Q;  2D96 A;  4F42 A;  2OF5 A;  2MN4 A;  4A2W A;  2N83 A;  4QOB A;  4I16 A;  1E41 A;  2M5V A;  2N80 A;  1E3Y A;  2L9M A;  3LQR A;  4F44 A;  4M9X A;  2YQF A;  2MS8 A;  2NZ7 A;  3MOP K;  2DO9 A;  4N1K A;  1FAD A;  2LS7 A;  4E9M A;  4UZ0 A;  1YGO A;  4P4H I;  2VGQ A;  4JUP A;  1WMG A;  3J63 A;  4P4H A;  2KN6 A;  4O9L A;  3YGS P;  3J6J A;  1N3K A;  1ICH A;  4FH0 A;  3T6P A;  3EZQ B;  2YU0 A;  1A1Z A;  2NAQ A;  4M9Z A;  2DBD A;  3MOP G;  2N00 A;  4O6X A;  1A1W A;  3KAT A;  2XV9 A;  3CL3 A;  4RHW E;  2DBH A;  2LWD A;  4N1L A;  4IZ7 B;  1DDF A;  4RHW A;  3LQQ A;  4A2Q A;  2OF5 H;  2BBR A;  4IZ5 E;  2P1H A;  2A9I A;  4O9F A;  3CRD A;  2B1W A;  3QF2 A;  1UCP A;  2A5Y B;  2MPC A;  4JQW A;  1Z6T A;  1PN5 A;  4N1J A;  2F1S A;  2LWE A;  2DBF A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...