3CL3A

Crystal structure of a vflip-ikkgamma complex: insights into viral activation of the ikk signalosome
Total Genus 57
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
57
sequence length
172
structure length
172
Chain Sequence
ATYEVLCEVARKLGTDDREVVLFLLNVFIPQPTLAQLIGALRALKEEGRLTFPLLAECLFRAGRRDLLRDLLHLDPRFLERHLAGTMSYFSPYQLTVLHVDGELCARDIRSLIFLSKDTIGSRSTPQTFLHWVYCMENLDLLGPTDVDALMSMLRSLSRVDLQRQVQTLMGL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Crystal structure of a vFlip-IKKgamma complex: insights into viral activation of the IKK signalosome.
pubmed doi rcsb
molecule tags Viral protein/signaling protein
source organism Human gammaherpesvirus 8
molecule keywords ORF K13
total genus 57
structure length 172
sequence length 172
chains with identical sequence B
ec nomenclature
pdb deposition date 2008-03-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01335 DED Death effector domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.533.10 Mainly Alpha Orthogonal Bundle Death Domain, Fas Death Domain, Fas 3cl3A02
1.10.533.10 Mainly Alpha Orthogonal Bundle Death Domain, Fas Death Domain, Fas 3cl3A01
4RHWE 4I16A 1CWWA 2HM2Q 2LWEA 2DBFA 1CY5A 3YGSP 1WMGA 2NSNA 1E41A 2L9MA 2O71A 3YGSC 3J63A 2G7RA 2OF5A 2N83A 4DWNA 3CRDA 2N97A 2KN6A 4JUPA 2LWDA 2N7ZA 3T6PA 1C15A 2MS7A 4A2QA 2OF5H 3J6JA 4M9SA 2N00A 1UCPA 2N80A 2YQFA 1A1WA 1DDFA 4N1KA 4N1LA 1FADA 4EWIA 4RHWA 2BBRA 2MPCA 2YU0A 1ICHA 2YVIA 4IZAB 2P1HA 3EZQA 2L6AA 2NZ7A 1PN5A 2MN4A 3LQRA 2MS8A 3LQQA 1WH4A 1NGRA 4F42A 2KM6A 4O9FA 4N1JA 2LS7A 2IB1A 3MOPG 3MOPA 4FH0A 4O9LA 2A5YB 2VGQA 4O7QA 2D96A 2DBGA 2A9IA 2BBZA 2GF5A 2MB9A 3EZQB 4M9XA 2NAQA 2DBDA 4NQKA 4IZ7B 4F44A 4UZ0A 1YGOA 4QOBA 3MOPK 2DO9A 2YGSA 1E3YA 2F1SA 3CL3A 1WXPA 4IZ5E 3KATA 4ZBWA 1Z6TA 1D2ZA 1N3KA 1D2ZB 2B1WA 2N1FA 4E9MA 1DGNA 4JQWA 4M9ZA 1A1ZA 4A2WA 2DBHA 4LWDA 4P4HA 2M5VA 4O6XA 4D8OA 3QF2A 4P4HI
chains in the Genus database with same CATH superfamily
4RHWE 4I16A 1CWWA 2HM2Q 2LWEA 2DBFA 1CY5A 3YGSP 1WMGA 2NSNA 1E41A 2L9MA 2O71A 2MJMA 3YGSC 3J63A 2G7RA 2OF5A 2N83A 4DWNA 3CRDA 2N97A 2KN6A 4JUPA 2LWDA 2N7ZA 3T6PA 1C15A 2MS7A 4A2QA 2OF5H 3J6JA 4M9SA 2N00A 1UCPA 2N80A 2YQFA 1A1WA 1DDFA 4N1KA 4N1LA 1FADA 4EWIA 4RHWA 2BBRA 2MPCA 2YU0A 1ICHA 2YVIA 4IZAB 2P1HA 3EZQA 2L6AA 2NZ7A 1PN5A 2MN4A 3LQRA 2MS8A 2XV9A 3LQQA 1WH4A 1NGRA 4F42A 2KM6A 4O9FA 4N1JA 2LS7A 2IB1A 3MOPG 3MOPA 4FH0A 4O9LA 2A5YB 2VGQA 4O7QA 2D96A 2DBGA 2A9IA 2BBZA 2GF5A 2MB9A 3EZQB 4M9XA 2NAQA 2DBDA 4NQKA 4IZ7B 4F44A 4UZ0A 1YGOA 4QOBA 3MOPK 2DO9A 2YGSA 1E3YA 2F1SA 3CL3A 1WXPA 4IZ5E 3KATA 4ZBWA 1Z6TA 1D2ZA 1N3KA 1D2ZB 2B1WA 2N1FA 4E9MA 1DGNA 4JQWA 4M9ZA 1A1ZA 4A2WA 2DBHA 4LWDA 4P4HA 2M5VA 4O6XA 4D8OA 3QF2A 4P4HI
chains in the Genus database with same CATH topology
4RHWE 4I16A 1CWWA 2HM2Q 2LWEA 2DBFA 1CY5A 3YGSP 1WMGA 2NSNA 1E41A 2L9MA 2O71A 2MJMA 3YGSC 3J63A 2G7RA 2OF5A 2N83A 4DWNA 3CRDA 2N97A 2KN6A 4JUPA 2LWDA 2N7ZA 3T6PA 1C15A 2MS7A 4A2QA 2OF5H 3J6JA 4M9SA 2N00A 1UCPA 2N80A 2YQFA 1A1WA 1DDFA 4N1KA 4N1LA 1FADA 4EWIA 4RHWA 2BBRA 2MPCA 2YU0A 1ICHA 2YVIA 4IZAB 2P1HA 3EZQA 2L6AA 2NZ7A 1PN5A 2MN4A 3LQRA 2MS8A 2XV9A 3LQQA 1WH4A 1NGRA 4F42A 2KM6A 4O9FA 4N1JA 2LS7A 2IB1A 3MOPG 3MOPA 4FH0A 4O9LA 2A5YB 2VGQA 4O7QA 2D96A 2DBGA 2A9IA 2BBZA 2GF5A 2MB9A 3EZQB 4M9XA 2NAQA 2DBDA 4NQKA 4IZ7B 4F44A 4UZ0A 1YGOA 4QOBA 3MOPK 2DO9A 2YGSA 1E3YA 2F1SA 3CL3A 1WXPA 4IZ5E 3KATA 4ZBWA 1Z6TA 1D2ZA 1N3KA 1D2ZB 2B1WA 2N1FA 4E9MA 1DGNA 4JQWA 4M9ZA 1A1ZA 4A2WA 2DBHA 4LWDA 4P4HA 2M5VA 4O6XA 4D8OA 3QF2A 4P4HI
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4RHW E;  4I16 A;  1CWW A;  2HM2 Q;  2LWE A;  2DBF A;  1CY5 A;  3YGS P;  1WMG A;  2NSN A;  1E41 A;  2L9M A;  2O71 A;  3YGS C;  3J63 A;  2G7R A;  2OF5 A;  2N83 A;  4DWN A;  3CRD A;  2N97 A;  2KN6 A;  4JUP A;  2LWD A;  2N7Z A;  3T6P A;  1C15 A;  2MS7 A;  4A2Q A;  2OF5 H;  3J6J A;  4M9S A;  2N00 A;  1UCP A;  2N80 A;  2YQF A;  1A1W A;  1DDF A;  4N1K A;  4N1L A;  1FAD A;  4EWI A;  4RHW A;  2BBR A;  2MPC A;  2YU0 A;  1ICH A;  2YVI A;  4IZA B;  2P1H A;  3EZQ A;  2L6A A;  2NZ7 A;  1PN5 A;  2MN4 A;  3LQR A;  2MS8 A;  3LQQ A;  1WH4 A;  1NGR A;  4F42 A;  2KM6 A;  4O9F A;  4N1J A;  2LS7 A;  2IB1 A;  3MOP G;  3MOP A;  4FH0 A;  4O9L A;  2A5Y B;  2VGQ A;  4O7Q A;  2D96 A;  2DBG A;  2A9I A;  2BBZ A;  2GF5 A;  2MB9 A;  3EZQ B;  4M9X A;  2NAQ A;  2DBD A;  4NQK A;  4IZ7 B;  4F44 A;  4UZ0 A;  1YGO A;  4QOB A;  3MOP K;  2DO9 A;  2YGS A;  1E3Y A;  2F1S A;  3CL3 A;  1WXP A;  4IZ5 E;  3KAT A;  4ZBW A;  1Z6T A;  1D2Z A;  1N3K A;  1D2Z B;  2B1W A;  2N1F A;  4E9M A;  1DGN A;  4JQW A;  4M9Z A;  1A1Z A;  4A2W A;  2DBH A;  4LWD A;  4P4H A;  2M5V A;  4O6X A;  4D8O A;  3QF2 A;  4P4H I; 
#chains in the Genus database with same CATH topology
 4RHW E;  4I16 A;  1CWW A;  2HM2 Q;  2LWE A;  2DBF A;  1CY5 A;  3YGS P;  1WMG A;  2NSN A;  1E41 A;  2L9M A;  2O71 A;  2MJM A;  3YGS C;  3J63 A;  2G7R A;  2OF5 A;  2N83 A;  4DWN A;  3CRD A;  2N97 A;  2KN6 A;  4JUP A;  2LWD A;  2N7Z A;  3T6P A;  1C15 A;  2MS7 A;  4A2Q A;  2OF5 H;  3J6J A;  4M9S A;  2N00 A;  1UCP A;  2N80 A;  2YQF A;  1A1W A;  1DDF A;  4N1K A;  4N1L A;  1FAD A;  4EWI A;  4RHW A;  2BBR A;  2MPC A;  2YU0 A;  1ICH A;  2YVI A;  4IZA B;  2P1H A;  3EZQ A;  2L6A A;  2NZ7 A;  1PN5 A;  2MN4 A;  3LQR A;  2MS8 A;  2XV9 A;  3LQQ A;  1WH4 A;  1NGR A;  4F42 A;  2KM6 A;  4O9F A;  4N1J A;  2LS7 A;  2IB1 A;  3MOP G;  3MOP A;  4FH0 A;  4O9L A;  2A5Y B;  2VGQ A;  4O7Q A;  2D96 A;  2DBG A;  2A9I A;  2BBZ A;  2GF5 A;  2MB9 A;  3EZQ B;  4M9X A;  2NAQ A;  2DBD A;  4NQK A;  4IZ7 B;  4F44 A;  4UZ0 A;  1YGO A;  4QOB A;  3MOP K;  2DO9 A;  2YGS A;  1E3Y A;  2F1S A;  3CL3 A;  1WXP A;  4IZ5 E;  3KAT A;  4ZBW A;  1Z6T A;  1D2Z A;  1N3K A;  1D2Z B;  2B1W A;  2N1F A;  4E9M A;  1DGN A;  4JQW A;  4M9Z A;  1A1Z A;  4A2W A;  2DBH A;  4LWD A;  4P4H A;  2M5V A;  4O6X A;  4D8O A;  3QF2 A;  4P4H I; 
#chains in the Genus database with same CATH homology
 4RHW E;  4I16 A;  1CWW A;  2HM2 Q;  2LWE A;  2DBF A;  1CY5 A;  3YGS P;  1WMG A;  2NSN A;  1E41 A;  2L9M A;  2O71 A;  2MJM A;  3YGS C;  3J63 A;  2G7R A;  2OF5 A;  2N83 A;  4DWN A;  3CRD A;  2N97 A;  2KN6 A;  4JUP A;  2LWD A;  2N7Z A;  3T6P A;  1C15 A;  2MS7 A;  4A2Q A;  2OF5 H;  3J6J A;  4M9S A;  2N00 A;  1UCP A;  2N80 A;  2YQF A;  1A1W A;  1DDF A;  4N1K A;  4N1L A;  1FAD A;  4EWI A;  4RHW A;  2BBR A;  2MPC A;  2YU0 A;  1ICH A;  2YVI A;  4IZA B;  2P1H A;  3EZQ A;  2L6A A;  2NZ7 A;  1PN5 A;  2MN4 A;  3LQR A;  2MS8 A;  2XV9 A;  3LQQ A;  1WH4 A;  1NGR A;  4F42 A;  2KM6 A;  4O9F A;  4N1J A;  2LS7 A;  2IB1 A;  3MOP G;  3MOP A;  4FH0 A;  4O9L A;  2A5Y B;  2VGQ A;  4O7Q A;  2D96 A;  2DBG A;  2A9I A;  2BBZ A;  2GF5 A;  2MB9 A;  3EZQ B;  4M9X A;  2NAQ A;  2DBD A;  4NQK A;  4IZ7 B;  4F44 A;  4UZ0 A;  1YGO A;  4QOB A;  3MOP K;  2DO9 A;  2YGS A;  1E3Y A;  2F1S A;  3CL3 A;  1WXP A;  4IZ5 E;  3KAT A;  4ZBW A;  1Z6T A;  1D2Z A;  1N3K A;  1D2Z B;  2B1W A;  2N1F A;  4E9M A;  1DGN A;  4JQW A;  4M9Z A;  1A1Z A;  4A2W A;  2DBH A;  4LWD A;  4P4H A;  2M5V A;  4O6X A;  4D8O A;  3QF2 A;  4P4H I; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...