3EZQB

Crystal structure of the fas/fadd death domain complex
Total Genus 36
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
36
sequence length
99
structure length
99
Chain Sequence
GEEDLCAAFNVICDNVGKDWRRLARQLKVSDTKIDSIEDRYPRNLTERVRESLRIWKNTEKENATVAHLVGALRSCQMNLVADLVQEVQQARDLQNRSG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title The Fas-FADD death domain complex structure unravels signalling by receptor clustering
pubmed doi rcsb
molecule tags Apoptosis
source organism Homo sapiens
molecule keywords Tumor necrosis factor receptor superfamily member 6
total genus 36
structure length 99
sequence length 99
chains with identical sequence D, F, H, J, L, N, P
ec nomenclature
pdb deposition date 2008-10-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00531 Death Death domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.533.10 Mainly Alpha Orthogonal Bundle Death Domain, Fas Death Domain, Fas 3ezqB00
2OF5A 4RHWE 2DO9A 1WH4A 3YGSP 1A1ZA 2MS8A 1UCPA 3CRDA 3J63A 4FH0A 3LQQA 4M9ZA 2N00A 3MOPA 4M9SA 2DBGA 4O6XA 2MB9A 4F42A 1CY5A 4NQKA 2F1SA 2YGSA 2M5VA 4E9MA 3YGSC 2N7ZA 4D8OA 4A2WA 1DDFA 2LWDA 2MPCA 2BBZA 4JQWA 1ICHA 2YVIA 1D2ZA 4QOBA 2DBHA 2KM6A 1WMGA 4N1JA 4M9XA 2N1FA 2N83A 1N3KA 1PN5A 4IZ7B 4RHWA 2HM2Q 4EWIA 4P4HI 4O7QA 1YGOA 2KN6A 4DWNA 1NGRA 4I16A 2L9MA 3EZQA 4P4HA 2A9IA 2YQFA 2A5YB 4UZ0A 3J6JA 3MOPG 1A1WA 4O9FA 2OF5H 3CL3A 2B1WA 2P1HA 4IZAB 2LS7A 2G7RA 1Z6TA 2DBFA 1CWWA 2YU0A 4F44A 4IZ5E 2NSNA 4N1LA 4O9LA 2IB1A 1D2ZB 2VGQA 3LQRA 2MN4A 4A2QA 2O71A 1E3YA 4N1KA 4JUPA 2NAQA 1C15A 2NZ7A 3KATA 4LWDA 2MS7A 2BBRA 3QF2A 2DBDA 2L6AA 3EZQB 1E41A 2N80A 1DGNA 2N97A 1FADA 2D96A 3MOPK 4ZBWA 1WXPA 2LWEA 3T6PA 2GF5A
chains in the Genus database with same CATH superfamily
2OF5A 4RHWE 2DO9A 1WH4A 3YGSP 1A1ZA 2MS8A 1UCPA 3CRDA 3J63A 4FH0A 3LQQA 4M9ZA 2N00A 3MOPA 4M9SA 2DBGA 4O6XA 2MB9A 4F42A 1CY5A 4NQKA 2F1SA 2YGSA 2M5VA 4E9MA 3YGSC 2N7ZA 4D8OA 4A2WA 1DDFA 2LWDA 2MPCA 2BBZA 4JQWA 1ICHA 2YVIA 1D2ZA 4QOBA 2DBHA 2KM6A 1WMGA 4N1JA 4M9XA 2N1FA 2N83A 1N3KA 1PN5A 4IZ7B 4RHWA 2HM2Q 4EWIA 4P4HI 4O7QA 1YGOA 2KN6A 4DWNA 1NGRA 4I16A 2L9MA 3EZQA 4P4HA 2A9IA 2YQFA 2A5YB 2MJMA 4UZ0A 3J6JA 3MOPG 1A1WA 4O9FA 2OF5H 3CL3A 2B1WA 2P1HA 2XV9A 4IZAB 2LS7A 2G7RA 1Z6TA 2DBFA 1CWWA 2YU0A 4F44A 4IZ5E 2NSNA 4N1LA 4O9LA 2IB1A 1D2ZB 2VGQA 3LQRA 2MN4A 4A2QA 2O71A 1E3YA 4N1KA 4JUPA 2NAQA 1C15A 2NZ7A 3KATA 4LWDA 2MS7A 2BBRA 3QF2A 2DBDA 2L6AA 3EZQB 1E41A 2N80A 1DGNA 2N97A 1FADA 2D96A 3MOPK 4ZBWA 1WXPA 2LWEA 3T6PA 2GF5A
chains in the Genus database with same CATH topology
2OF5A 4RHWE 2DO9A 1WH4A 3YGSP 1A1ZA 2MS8A 1UCPA 3CRDA 3J63A 4FH0A 3LQQA 4M9ZA 2N00A 3MOPA 4M9SA 2DBGA 4O6XA 2MB9A 4F42A 1CY5A 4NQKA 2F1SA 2YGSA 2M5VA 4E9MA 3YGSC 2N7ZA 4D8OA 4A2WA 1DDFA 2LWDA 2MPCA 2BBZA 4JQWA 1ICHA 2YVIA 1D2ZA 4QOBA 2DBHA 2KM6A 1WMGA 4N1JA 4M9XA 2N1FA 2N83A 1N3KA 1PN5A 4IZ7B 4RHWA 2HM2Q 4EWIA 4P4HI 4O7QA 1YGOA 2KN6A 4DWNA 1NGRA 4I16A 2L9MA 3EZQA 4P4HA 2A9IA 2YQFA 2A5YB 2MJMA 4UZ0A 3J6JA 3MOPG 1A1WA 4O9FA 2OF5H 3CL3A 2B1WA 2P1HA 2XV9A 4IZAB 2LS7A 2G7RA 1Z6TA 2DBFA 1CWWA 2YU0A 4F44A 4IZ5E 2NSNA 4N1LA 4O9LA 2IB1A 1D2ZB 2VGQA 3LQRA 2MN4A 4A2QA 2O71A 1E3YA 4N1KA 4JUPA 2NAQA 1C15A 2NZ7A 3KATA 4LWDA 2MS7A 2BBRA 3QF2A 2DBDA 2L6AA 3EZQB 1E41A 2N80A 1DGNA 2N97A 1FADA 2D96A 3MOPK 4ZBWA 1WXPA 2LWEA 3T6PA 2GF5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2OF5 A;  4RHW E;  2DO9 A;  1WH4 A;  3YGS P;  1A1Z A;  2MS8 A;  1UCP A;  3CRD A;  3J63 A;  4FH0 A;  3LQQ A;  4M9Z A;  2N00 A;  3MOP A;  4M9S A;  2DBG A;  4O6X A;  2MB9 A;  4F42 A;  1CY5 A;  4NQK A;  2F1S A;  2YGS A;  2M5V A;  4E9M A;  3YGS C;  2N7Z A;  4D8O A;  4A2W A;  1DDF A;  2LWD A;  2MPC A;  2BBZ A;  4JQW A;  1ICH A;  2YVI A;  1D2Z A;  4QOB A;  2DBH A;  2KM6 A;  1WMG A;  4N1J A;  4M9X A;  2N1F A;  2N83 A;  1N3K A;  1PN5 A;  4IZ7 B;  4RHW A;  2HM2 Q;  4EWI A;  4P4H I;  4O7Q A;  1YGO A;  2KN6 A;  4DWN A;  1NGR A;  4I16 A;  2L9M A;  3EZQ A;  4P4H A;  2A9I A;  2YQF A;  2A5Y B;  4UZ0 A;  3J6J A;  3MOP G;  1A1W A;  4O9F A;  2OF5 H;  3CL3 A;  2B1W A;  2P1H A;  4IZA B;  2LS7 A;  2G7R A;  1Z6T A;  2DBF A;  1CWW A;  2YU0 A;  4F44 A;  4IZ5 E;  2NSN A;  4N1L A;  4O9L A;  2IB1 A;  1D2Z B;  2VGQ A;  3LQR A;  2MN4 A;  4A2Q A;  2O71 A;  1E3Y A;  4N1K A;  4JUP A;  2NAQ A;  1C15 A;  2NZ7 A;  3KAT A;  4LWD A;  2MS7 A;  2BBR A;  3QF2 A;  2DBD A;  2L6A A;  3EZQ B;  1E41 A;  2N80 A;  1DGN A;  2N97 A;  1FAD A;  2D96 A;  3MOP K;  4ZBW A;  1WXP A;  2LWE A;  3T6P A;  2GF5 A; 
#chains in the Genus database with same CATH topology
 2OF5 A;  4RHW E;  2DO9 A;  1WH4 A;  3YGS P;  1A1Z A;  2MS8 A;  1UCP A;  3CRD A;  3J63 A;  4FH0 A;  3LQQ A;  4M9Z A;  2N00 A;  3MOP A;  4M9S A;  2DBG A;  4O6X A;  2MB9 A;  4F42 A;  1CY5 A;  4NQK A;  2F1S A;  2YGS A;  2M5V A;  4E9M A;  3YGS C;  2N7Z A;  4D8O A;  4A2W A;  1DDF A;  2LWD A;  2MPC A;  2BBZ A;  4JQW A;  1ICH A;  2YVI A;  1D2Z A;  4QOB A;  2DBH A;  2KM6 A;  1WMG A;  4N1J A;  4M9X A;  2N1F A;  2N83 A;  1N3K A;  1PN5 A;  4IZ7 B;  4RHW A;  2HM2 Q;  4EWI A;  4P4H I;  4O7Q A;  1YGO A;  2KN6 A;  4DWN A;  1NGR A;  4I16 A;  2L9M A;  3EZQ A;  4P4H A;  2A9I A;  2YQF A;  2A5Y B;  2MJM A;  4UZ0 A;  3J6J A;  3MOP G;  1A1W A;  4O9F A;  2OF5 H;  3CL3 A;  2B1W A;  2P1H A;  2XV9 A;  4IZA B;  2LS7 A;  2G7R A;  1Z6T A;  2DBF A;  1CWW A;  2YU0 A;  4F44 A;  4IZ5 E;  2NSN A;  4N1L A;  4O9L A;  2IB1 A;  1D2Z B;  2VGQ A;  3LQR A;  2MN4 A;  4A2Q A;  2O71 A;  1E3Y A;  4N1K A;  4JUP A;  2NAQ A;  1C15 A;  2NZ7 A;  3KAT A;  4LWD A;  2MS7 A;  2BBR A;  3QF2 A;  2DBD A;  2L6A A;  3EZQ B;  1E41 A;  2N80 A;  1DGN A;  2N97 A;  1FAD A;  2D96 A;  3MOP K;  4ZBW A;  1WXP A;  2LWE A;  3T6P A;  2GF5 A; 
#chains in the Genus database with same CATH homology
 2OF5 A;  4RHW E;  2DO9 A;  1WH4 A;  3YGS P;  1A1Z A;  2MS8 A;  1UCP A;  3CRD A;  3J63 A;  4FH0 A;  3LQQ A;  4M9Z A;  2N00 A;  3MOP A;  4M9S A;  2DBG A;  4O6X A;  2MB9 A;  4F42 A;  1CY5 A;  4NQK A;  2F1S A;  2YGS A;  2M5V A;  4E9M A;  3YGS C;  2N7Z A;  4D8O A;  4A2W A;  1DDF A;  2LWD A;  2MPC A;  2BBZ A;  4JQW A;  1ICH A;  2YVI A;  1D2Z A;  4QOB A;  2DBH A;  2KM6 A;  1WMG A;  4N1J A;  4M9X A;  2N1F A;  2N83 A;  1N3K A;  1PN5 A;  4IZ7 B;  4RHW A;  2HM2 Q;  4EWI A;  4P4H I;  4O7Q A;  1YGO A;  2KN6 A;  4DWN A;  1NGR A;  4I16 A;  2L9M A;  3EZQ A;  4P4H A;  2A9I A;  2YQF A;  2A5Y B;  2MJM A;  4UZ0 A;  3J6J A;  3MOP G;  1A1W A;  4O9F A;  2OF5 H;  3CL3 A;  2B1W A;  2P1H A;  2XV9 A;  4IZA B;  2LS7 A;  2G7R A;  1Z6T A;  2DBF A;  1CWW A;  2YU0 A;  4F44 A;  4IZ5 E;  2NSN A;  4N1L A;  4O9L A;  2IB1 A;  1D2Z B;  2VGQ A;  3LQR A;  2MN4 A;  4A2Q A;  2O71 A;  1E3Y A;  4N1K A;  4JUP A;  2NAQ A;  1C15 A;  2NZ7 A;  3KAT A;  4LWD A;  2MS7 A;  2BBR A;  3QF2 A;  2DBD A;  2L6A A;  3EZQ B;  1E41 A;  2N80 A;  1DGN A;  2N97 A;  1FAD A;  2D96 A;  3MOP K;  4ZBW A;  1WXP A;  2LWE A;  3T6P A;  2GF5 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...