3QF2 | Genus

Total Genus 32

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	32
sequence length	90
structure length	90
Chain Sequence	STRCKLARYLEDLEDVDLKKFKMHLEDYPPQKGCIPLPRGQTEKADHVDLATLMIDFNGEEKAWAMAVWIFAAINRRDLYEKAKRDEPKW

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Apoptosis
source organism	Homo sapiens
publication title	Crystal Structure of NALP3 Protein Pyrin Domain (PYD) and Its Implications in Inflammasome Assembly pubmed doi rcsb
molecule keywords	NACHT, LRR and PYD domains-containing protein 3
total genus	32
structure length	90
sequence length	90
chains with identical sequence	B
ec nomenclature
pdb deposition date	2011-01-21

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF02758	PYRIN	PAAD/DAPIN/Pyrin domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.10.533.10	Mainly Alpha	Orthogonal Bundle	Death Domain, Fas	Death Domain, Fas	3qf2A00

4FH0A 2YVIA 4N1LA 4RHWA 2DBGA 4IZ7B 4D8OA 2YGSA 4O9FA 4O9LA 3MOPA 2DBDA 2O71A 2LS7A 2MN4A 1N3KA 2DBFA 4A2QA 3J6JA 1CY5A 2HM2Q 1WXPA 2NAQA 2P1HA 4IZAB 4O6XA 2N83A 4F42A 3YGSC 2MS7A 1NGRA 4ZBWA 2VGQA 3MOPG 4A2WA 4M9XA 3EZQB 3CL3A 3YGSP 1ICHA 1DDFA 4P4HI 4NQKA 2A9IA 2D96A 2B1WA 4JUPA 2BBRA 2G7RA 2OF5H 4N1KA 1D2ZB 1YGOA 4M9SA 4N1JA 3CRDA 3LQRA 2DO9A 4LWDA 1DGNA 2L9MA 4O7QA 3J63A 1E41A 4M9ZA 2YU0A 1D2ZA 4RHWE 1PN5A 4EWIA 1A1ZA 2GF5A 3KATA 4F44A 1A1WA 4P4HA 2KM6A 2N80A 3QF2A 2L6AA 3EZQA 4JQWA 1CWWA 4I16A 1C15A 2MB9A 2M5VA 1WMGA 2N7ZA 2N00A 3T6PA 2LWDA 1UCPA 4E9MA 1FADA 2N97A 2F1SA 4IZ5E 2OF5A 1E3YA 2NZ7A 4QOBA 2YQFA 3LQQA 2IB1A 2KN6A 4DWNA 1Z6TA 1WH4A 2MS8A 2N1FA 2MPCA 3MOPK 2A5YB 2DBHA 4UZ0A 2BBZA 2NSNA 2LWEA
chains in the Genus database with same CATH superfamily

4FH0A 2YVIA 4N1LA 4RHWA 2DBGA 4IZ7B 4D8OA 2YGSA 4O9FA 4O9LA 2XV9A 3MOPA 2DBDA 2O71A 2LS7A 2MN4A 1N3KA 2DBFA 4A2QA 3J6JA 1CY5A 2HM2Q 1WXPA 2NAQA 2P1HA 4IZAB 4O6XA 2N83A 4F42A 3YGSC 2MS7A 1NGRA 4ZBWA 2VGQA 2MJMA 3MOPG 4A2WA 4M9XA 3EZQB 3CL3A 3YGSP 1ICHA 1DDFA 4P4HI 4NQKA 2A9IA 2D96A 2B1WA 4JUPA 2BBRA 2G7RA 2OF5H 4N1KA 1D2ZB 1YGOA 4M9SA 4N1JA 3CRDA 3LQRA 2DO9A 4LWDA 1DGNA 2L9MA 4O7QA 3J63A 1E41A 4M9ZA 2YU0A 1D2ZA 4RHWE 1PN5A 4EWIA 1A1ZA 2GF5A 3KATA 4F44A 1A1WA 4P4HA 2KM6A 2N80A 3QF2A 2L6AA 3EZQA 4JQWA 1CWWA 4I16A 1C15A 2MB9A 2M5VA 1WMGA 2N7ZA 2N00A 3T6PA 2LWDA 1UCPA 4E9MA 1FADA 2N97A 2F1SA 4IZ5E 2OF5A 1E3YA 2NZ7A 4QOBA 2YQFA 3LQQA 2IB1A 2KN6A 4DWNA 1Z6TA 1WH4A 2MS8A 2N1FA 2MPCA 3MOPK 2A5YB 2DBHA 4UZ0A 2BBZA 2NSNA 2LWEA
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 4FH0 A;  2YVI A;  4N1L A;  4RHW A;  2DBG A;  4IZ7 B;  4D8O A;  2YGS A;  4O9F A;  4O9L A;  3MOP A;  2DBD A;  2O71 A;  2LS7 A;  2MN4 A;  1N3K A;  2DBF A;  4A2Q A;  3J6J A;  1CY5 A;  2HM2 Q;  1WXP A;  2NAQ A;  2P1H A;  4IZA B;  4O6X A;  2N83 A;  4F42 A;  3YGS C;  2MS7 A;  1NGR A;  4ZBW A;  2VGQ A;  3MOP G;  4A2W A;  4M9X A;  3EZQ B;  3CL3 A;  3YGS P;  1ICH A;  1DDF A;  4P4H I;  4NQK A;  2A9I A;  2D96 A;  2B1W A;  4JUP A;  2BBR A;  2G7R A;  2OF5 H;  4N1K A;  1D2Z B;  1YGO A;  4M9S A;  4N1J A;  3CRD A;  3LQR A;  2DO9 A;  4LWD A;  1DGN A;  2L9M A;  4O7Q A;  3J63 A;  1E41 A;  4M9Z A;  2YU0 A;  1D2Z A;  4RHW E;  1PN5 A;  4EWI A;  1A1Z A;  2GF5 A;  3KAT A;  4F44 A;  1A1W A;  4P4H A;  2KM6 A;  2N80 A;  3QF2 A;  2L6A A;  3EZQ A;  4JQW A;  1CWW A;  4I16 A;  1C15 A;  2MB9 A;  2M5V A;  1WMG A;  2N7Z A;  2N00 A;  3T6P A;  2LWD A;  1UCP A;  4E9M A;  1FAD A;  2N97 A;  2F1S A;  4IZ5 E;  2OF5 A;  1E3Y A;  2NZ7 A;  4QOB A;  2YQF A;  3LQQ A;  2IB1 A;  2KN6 A;  4DWN A;  1Z6T A;  1WH4 A;  2MS8 A;  2N1F A;  2MPC A;  3MOP K;  2A5Y B;  2DBH A;  4UZ0 A;  2BBZ A;  2NSN A;  2LWE A; 
#chains in the Genus database with same CATH topology
 4FH0 A;  2YVI A;  4N1L A;  4RHW A;  2DBG A;  4IZ7 B;  4D8O A;  2YGS A;  4O9F A;  4O9L A;  2XV9 A;  3MOP A;  2DBD A;  2O71 A;  2LS7 A;  2MN4 A;  1N3K A;  2DBF A;  4A2Q A;  3J6J A;  1CY5 A;  2HM2 Q;  1WXP A;  2NAQ A;  2P1H A;  4IZA B;  4O6X A;  2N83 A;  4F42 A;  3YGS C;  2MS7 A;  1NGR A;  4ZBW A;  2VGQ A;  2MJM A;  3MOP G;  4A2W A;  4M9X A;  3EZQ B;  3CL3 A;  3YGS P;  1ICH A;  1DDF A;  4P4H I;  4NQK A;  2A9I A;  2D96 A;  2B1W A;  4JUP A;  2BBR A;  2G7R A;  2OF5 H;  4N1K A;  1D2Z B;  1YGO A;  4M9S A;  4N1J A;  3CRD A;  3LQR A;  2DO9 A;  4LWD A;  1DGN A;  2L9M A;  4O7Q A;  3J63 A;  1E41 A;  4M9Z A;  2YU0 A;  1D2Z A;  4RHW E;  1PN5 A;  4EWI A;  1A1Z A;  2GF5 A;  3KAT A;  4F44 A;  1A1W A;  4P4H A;  2KM6 A;  2N80 A;  3QF2 A;  2L6A A;  3EZQ A;  4JQW A;  1CWW A;  4I16 A;  1C15 A;  2MB9 A;  2M5V A;  1WMG A;  2N7Z A;  2N00 A;  3T6P A;  2LWD A;  1UCP A;  4E9M A;  1FAD A;  2N97 A;  2F1S A;  4IZ5 E;  2OF5 A;  1E3Y A;  2NZ7 A;  4QOB A;  2YQF A;  3LQQ A;  2IB1 A;  2KN6 A;  4DWN A;  1Z6T A;  1WH4 A;  2MS8 A;  2N1F A;  2MPC A;  3MOP K;  2A5Y B;  2DBH A;  4UZ0 A;  2BBZ A;  2NSN A;  2LWE A; 
#chains in the Genus database with same CATH homology
 4FH0 A;  2YVI A;  4N1L A;  4RHW A;  2DBG A;  4IZ7 B;  4D8O A;  2YGS A;  4O9F A;  4O9L A;  2XV9 A;  3MOP A;  2DBD A;  2O71 A;  2LS7 A;  2MN4 A;  1N3K A;  2DBF A;  4A2Q A;  3J6J A;  1CY5 A;  2HM2 Q;  1WXP A;  2NAQ A;  2P1H A;  4IZA B;  4O6X A;  2N83 A;  4F42 A;  3YGS C;  2MS7 A;  1NGR A;  4ZBW A;  2VGQ A;  2MJM A;  3MOP G;  4A2W A;  4M9X A;  3EZQ B;  3CL3 A;  3YGS P;  1ICH A;  1DDF A;  4P4H I;  4NQK A;  2A9I A;  2D96 A;  2B1W A;  4JUP A;  2BBR A;  2G7R A;  2OF5 H;  4N1K A;  1D2Z B;  1YGO A;  4M9S A;  4N1J A;  3CRD A;  3LQR A;  2DO9 A;  4LWD A;  1DGN A;  2L9M A;  4O7Q A;  3J63 A;  1E41 A;  4M9Z A;  2YU0 A;  1D2Z A;  4RHW E;  1PN5 A;  4EWI A;  1A1Z A;  2GF5 A;  3KAT A;  4F44 A;  1A1W A;  4P4H A;  2KM6 A;  2N80 A;  3QF2 A;  2L6A A;  3EZQ A;  4JQW A;  1CWW A;  4I16 A;  1C15 A;  2MB9 A;  2M5V A;  1WMG A;  2N7Z A;  2N00 A;  3T6P A;  2LWD A;  1UCP A;  4E9M A;  1FAD A;  2N97 A;  2F1S A;  4IZ5 E;  2OF5 A;  1E3Y A;  2NZ7 A;  4QOB A;  2YQF A;  3LQQ A;  2IB1 A;  2KN6 A;  4DWN A;  1Z6T A;  1WH4 A;  2MS8 A;  2N1F A;  2MPC A;  3MOP K;  2A5Y B;  2DBH A;  4UZ0 A;  2BBZ A;  2NSN A;  2LWE A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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3QF2A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations