4F42A

Neurotrophin p75ntr intracellular domain
Total Genus 27
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
27
sequence length
84
structure length
84
Chain Sequence
GNLYSSLPLTKREEVEKLLNGDTWRHLAGELGYQPEHIDSFTHEACPVRALLASWGAQDSATLDALLAALRRIQRADIVESLCS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural insights into the allosteric activation mechanism of p75NTR
rcsb
molecule tags Signaling protein
source organism Rattus norvegicus
molecule keywords Tumor necrosis factor receptor superfamily member 16
total genus 27
structure length 84
sequence length 84
ec nomenclature
pdb deposition date 2012-05-09
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.533.10 Mainly Alpha Orthogonal Bundle Death Domain, Fas Death Domain, Fas 4f42A00
4A2QA 4IZ7B 4P4HI 1C15A 4F44A 4RHWE 3QF2A 4O6XA 4N1KA 1E3YA 4I16A 1DDFA 2VGQA 2DBFA 3YGSP 3EZQB 1CWWA 4RHWA 4F42A 2DBDA 3KATA 1A1WA 2OF5H 4N1JA 3MOPA 4JUPA 4M9ZA 4IZAB 1PN5A 2MPCA 2LWEA 2MS7A 4LWDA 4EWIA 4A2WA 1YGOA 1FADA 2N80A 1N3KA 3MOPG 2P1HA 2N97A 4M9XA 4E9MA 2L6AA 4N1LA 3J6JA 1WXPA 3MOPK 2MS8A 2BBRA 2MN4A 2BBZA 3CRDA 4M9SA 2M5VA 2OF5A 1UCPA 2YQFA 1DGNA 2D96A 1ICHA 1D2ZB 4JQWA 2MB9A 4UZ0A 1A1ZA 1NGRA 3T6PA 2NZ7A 2GF5A 3LQQA 3LQRA 1D2ZA 2A9IA 2B1WA 2N00A 2O71A 2IB1A 2DBHA 2KN6A 2YVIA 2A5YB 2L9MA 2N83A 4P4HA 2LWDA 1Z6TA 4D8OA 4DWNA 2F1SA 1WH4A 2HM2Q 4IZ5E 4O7QA 2G7RA 2NSNA 3J63A 1E41A 4FH0A 1WMGA 4O9LA 2NAQA 2LS7A 3YGSC 2KM6A 2YU0A 4ZBWA 1CY5A 2DO9A 2N7ZA 2YGSA 4NQKA 4QOBA 3EZQA 2DBGA 4O9FA 3CL3A 2N1FA
chains in the Genus database with same CATH superfamily
4A2QA 4IZ7B 4P4HI 1C15A 4F44A 4RHWE 3QF2A 4O6XA 4N1KA 1E3YA 4I16A 1DDFA 2VGQA 2DBFA 3YGSP 3EZQB 1CWWA 4RHWA 4F42A 2DBDA 3KATA 1A1WA 2OF5H 4N1JA 3MOPA 4JUPA 4M9ZA 4IZAB 1PN5A 2MPCA 2LWEA 2MS7A 4LWDA 4EWIA 4A2WA 1YGOA 1FADA 2N80A 1N3KA 3MOPG 2P1HA 2N97A 4M9XA 4E9MA 2L6AA 4N1LA 3J6JA 1WXPA 3MOPK 2XV9A 2MS8A 2BBRA 2MN4A 2BBZA 3CRDA 4M9SA 2M5VA 2OF5A 1UCPA 2YQFA 1DGNA 2D96A 1ICHA 1D2ZB 4JQWA 2MB9A 4UZ0A 1A1ZA 1NGRA 3T6PA 2NZ7A 2GF5A 3LQQA 3LQRA 1D2ZA 2A9IA 2B1WA 2N00A 2O71A 2IB1A 2DBHA 2KN6A 2YVIA 2A5YB 2L9MA 2N83A 4P4HA 2LWDA 1Z6TA 4D8OA 4DWNA 2F1SA 1WH4A 2HM2Q 4IZ5E 2MJMA 4O7QA 2G7RA 2NSNA 3J63A 1E41A 4FH0A 1WMGA 4O9LA 2NAQA 2LS7A 3YGSC 2KM6A 2YU0A 4ZBWA 1CY5A 2DO9A 2N7ZA 2YGSA 4NQKA 4QOBA 3EZQA 2DBGA 4O9FA 3CL3A 2N1FA
chains in the Genus database with same CATH topology
4A2QA 4IZ7B 4P4HI 1C15A 4F44A 4RHWE 3QF2A 4O6XA 4N1KA 1E3YA 4I16A 1DDFA 2VGQA 2DBFA 3YGSP 3EZQB 1CWWA 4RHWA 4F42A 2DBDA 3KATA 1A1WA 2OF5H 4N1JA 3MOPA 4JUPA 4M9ZA 4IZAB 1PN5A 2MPCA 2LWEA 2MS7A 4LWDA 4EWIA 4A2WA 1YGOA 1FADA 2N80A 1N3KA 3MOPG 2P1HA 2N97A 4M9XA 4E9MA 2L6AA 4N1LA 3J6JA 1WXPA 3MOPK 2XV9A 2MS8A 2BBRA 2MN4A 2BBZA 3CRDA 4M9SA 2M5VA 2OF5A 1UCPA 2YQFA 1DGNA 2D96A 1ICHA 1D2ZB 4JQWA 2MB9A 4UZ0A 1A1ZA 1NGRA 3T6PA 2NZ7A 2GF5A 3LQQA 3LQRA 1D2ZA 2A9IA 2B1WA 2N00A 2O71A 2IB1A 2DBHA 2KN6A 2YVIA 2A5YB 2L9MA 2N83A 4P4HA 2LWDA 1Z6TA 4D8OA 4DWNA 2F1SA 1WH4A 2HM2Q 4IZ5E 2MJMA 4O7QA 2G7RA 2NSNA 3J63A 1E41A 4FH0A 1WMGA 4O9LA 2NAQA 2LS7A 3YGSC 2KM6A 2YU0A 4ZBWA 1CY5A 2DO9A 2N7ZA 2YGSA 4NQKA 4QOBA 3EZQA 2DBGA 4O9FA 3CL3A 2N1FA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4A2Q A;  4IZ7 B;  4P4H I;  1C15 A;  4F44 A;  4RHW E;  3QF2 A;  4O6X A;  4N1K A;  1E3Y A;  4I16 A;  1DDF A;  2VGQ A;  2DBF A;  3YGS P;  3EZQ B;  1CWW A;  4RHW A;  4F42 A;  2DBD A;  3KAT A;  1A1W A;  2OF5 H;  4N1J A;  3MOP A;  4JUP A;  4M9Z A;  4IZA B;  1PN5 A;  2MPC A;  2LWE A;  2MS7 A;  4LWD A;  4EWI A;  4A2W A;  1YGO A;  1FAD A;  2N80 A;  1N3K A;  3MOP G;  2P1H A;  2N97 A;  4M9X A;  4E9M A;  2L6A A;  4N1L A;  3J6J A;  1WXP A;  3MOP K;  2MS8 A;  2BBR A;  2MN4 A;  2BBZ A;  3CRD A;  4M9S A;  2M5V A;  2OF5 A;  1UCP A;  2YQF A;  1DGN A;  2D96 A;  1ICH A;  1D2Z B;  4JQW A;  2MB9 A;  4UZ0 A;  1A1Z A;  1NGR A;  3T6P A;  2NZ7 A;  2GF5 A;  3LQQ A;  3LQR A;  1D2Z A;  2A9I A;  2B1W A;  2N00 A;  2O71 A;  2IB1 A;  2DBH A;  2KN6 A;  2YVI A;  2A5Y B;  2L9M A;  2N83 A;  4P4H A;  2LWD A;  1Z6T A;  4D8O A;  4DWN A;  2F1S A;  1WH4 A;  2HM2 Q;  4IZ5 E;  4O7Q A;  2G7R A;  2NSN A;  3J63 A;  1E41 A;  4FH0 A;  1WMG A;  4O9L A;  2NAQ A;  2LS7 A;  3YGS C;  2KM6 A;  2YU0 A;  4ZBW A;  1CY5 A;  2DO9 A;  2N7Z A;  2YGS A;  4NQK A;  4QOB A;  3EZQ A;  2DBG A;  4O9F A;  3CL3 A;  2N1F A; 
#chains in the Genus database with same CATH topology
 4A2Q A;  4IZ7 B;  4P4H I;  1C15 A;  4F44 A;  4RHW E;  3QF2 A;  4O6X A;  4N1K A;  1E3Y A;  4I16 A;  1DDF A;  2VGQ A;  2DBF A;  3YGS P;  3EZQ B;  1CWW A;  4RHW A;  4F42 A;  2DBD A;  3KAT A;  1A1W A;  2OF5 H;  4N1J A;  3MOP A;  4JUP A;  4M9Z A;  4IZA B;  1PN5 A;  2MPC A;  2LWE A;  2MS7 A;  4LWD A;  4EWI A;  4A2W A;  1YGO A;  1FAD A;  2N80 A;  1N3K A;  3MOP G;  2P1H A;  2N97 A;  4M9X A;  4E9M A;  2L6A A;  4N1L A;  3J6J A;  1WXP A;  3MOP K;  2XV9 A;  2MS8 A;  2BBR A;  2MN4 A;  2BBZ A;  3CRD A;  4M9S A;  2M5V A;  2OF5 A;  1UCP A;  2YQF A;  1DGN A;  2D96 A;  1ICH A;  1D2Z B;  4JQW A;  2MB9 A;  4UZ0 A;  1A1Z A;  1NGR A;  3T6P A;  2NZ7 A;  2GF5 A;  3LQQ A;  3LQR A;  1D2Z A;  2A9I A;  2B1W A;  2N00 A;  2O71 A;  2IB1 A;  2DBH A;  2KN6 A;  2YVI A;  2A5Y B;  2L9M A;  2N83 A;  4P4H A;  2LWD A;  1Z6T A;  4D8O A;  4DWN A;  2F1S A;  1WH4 A;  2HM2 Q;  4IZ5 E;  2MJM A;  4O7Q A;  2G7R A;  2NSN A;  3J63 A;  1E41 A;  4FH0 A;  1WMG A;  4O9L A;  2NAQ A;  2LS7 A;  3YGS C;  2KM6 A;  2YU0 A;  4ZBW A;  1CY5 A;  2DO9 A;  2N7Z A;  2YGS A;  4NQK A;  4QOB A;  3EZQ A;  2DBG A;  4O9F A;  3CL3 A;  2N1F A; 
#chains in the Genus database with same CATH homology
 4A2Q A;  4IZ7 B;  4P4H I;  1C15 A;  4F44 A;  4RHW E;  3QF2 A;  4O6X A;  4N1K A;  1E3Y A;  4I16 A;  1DDF A;  2VGQ A;  2DBF A;  3YGS P;  3EZQ B;  1CWW A;  4RHW A;  4F42 A;  2DBD A;  3KAT A;  1A1W A;  2OF5 H;  4N1J A;  3MOP A;  4JUP A;  4M9Z A;  4IZA B;  1PN5 A;  2MPC A;  2LWE A;  2MS7 A;  4LWD A;  4EWI A;  4A2W A;  1YGO A;  1FAD A;  2N80 A;  1N3K A;  3MOP G;  2P1H A;  2N97 A;  4M9X A;  4E9M A;  2L6A A;  4N1L A;  3J6J A;  1WXP A;  3MOP K;  2XV9 A;  2MS8 A;  2BBR A;  2MN4 A;  2BBZ A;  3CRD A;  4M9S A;  2M5V A;  2OF5 A;  1UCP A;  2YQF A;  1DGN A;  2D96 A;  1ICH A;  1D2Z B;  4JQW A;  2MB9 A;  4UZ0 A;  1A1Z A;  1NGR A;  3T6P A;  2NZ7 A;  2GF5 A;  3LQQ A;  3LQR A;  1D2Z A;  2A9I A;  2B1W A;  2N00 A;  2O71 A;  2IB1 A;  2DBH A;  2KN6 A;  2YVI A;  2A5Y B;  2L9M A;  2N83 A;  4P4H A;  2LWD A;  1Z6T A;  4D8O A;  4DWN A;  2F1S A;  1WH4 A;  2HM2 Q;  4IZ5 E;  2MJM A;  4O7Q A;  2G7R A;  2NSN A;  3J63 A;  1E41 A;  4FH0 A;  1WMG A;  4O9L A;  2NAQ A;  2LS7 A;  3YGS C;  2KM6 A;  2YU0 A;  4ZBW A;  1CY5 A;  2DO9 A;  2N7Z A;  2YGS A;  4NQK A;  4QOB A;  3EZQ A;  2DBG A;  4O9F A;  3CL3 A;  2N1F A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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