4F44A

Neurotrophin p75ntr intracellular domain
Total Genus 26
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
26
sequence length
83
structure length
83
Chain Sequence
NLYSSLPLTKREEVEKLLNGDTWRHLAGELGYQPEHIDSFTHEACPVRALLASWGAQDSATLDALLAALRRIQRADIVESLCS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structural insights into the allosteric activation mechanism of p75NTR
rcsb
molecule tags Signaling protein
source organism Rattus norvegicus
molecule keywords Tumor necrosis factor receptor superfamily member 16
total genus 26
structure length 83
sequence length 83
chains with identical sequence B
ec nomenclature
pdb deposition date 2012-05-10
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.533.10 Mainly Alpha Orthogonal Bundle Death Domain, Fas Death Domain, Fas 4f44A00
1NGRA 2L9MA 2LWEA 4IZ5E 4NQKA 4JUPA 2O71A 1ICHA 4LWDA 4N1LA 1E41A 2GF5A 1DDFA 4O6XA 2DO9A 2N83A 4UZ0A 1N3KA 3EZQA 4O9LA 1PN5A 1CY5A 2NSNA 2BBRA 4M9XA 4O7QA 4IZ7B 4RHWE 2OF5H 3J63A 1D2ZA 2DBGA 2L6AA 3CRDA 2NZ7A 4D8OA 2P1HA 3CL3A 2MN4A 2A9IA 2MS7A 4E9MA 4IZAB 2YVIA 1WXPA 4QOBA 4I16A 2M5VA 2B1WA 2MPCA 2DBHA 1D2ZB 4A2WA 2OF5A 2D96A 3KATA 3LQRA 1E3YA 4F44A 4ZBWA 3YGSP 2HM2Q 2MB9A 1YGOA 2F1SA 3J6JA 2N1FA 3EZQB 3MOPA 4F42A 1A1WA 4A2QA 2KN6A 4M9SA 4EWIA 1A1ZA 2YQFA 1WH4A 2IB1A 3MOPK 1FADA 4N1KA 2N7ZA 2BBZA 1Z6TA 1DGNA 2N00A 2LWDA 2N80A 4JQWA 4M9ZA 3T6PA 4P4HI 1C15A 2KM6A 2LS7A 4P4HA 3YGSC 4DWNA 4RHWA 2YGSA 3LQQA 3QF2A 1UCPA 4N1JA 1WMGA 2NAQA 2YU0A 1CWWA 2N97A 3MOPG 2G7RA 2MS8A 4O9FA 2DBFA 2A5YB 4FH0A 2VGQA 2DBDA
chains in the Genus database with same CATH superfamily
1NGRA 2L9MA 2LWEA 4IZ5E 4NQKA 4JUPA 2XV9A 2O71A 1ICHA 2MJMA 4LWDA 4N1LA 1E41A 2GF5A 1DDFA 4O6XA 2DO9A 2N83A 4UZ0A 1N3KA 3EZQA 4O9LA 1PN5A 1CY5A 2NSNA 2BBRA 4M9XA 4O7QA 4IZ7B 4RHWE 2OF5H 3J63A 1D2ZA 2DBGA 2L6AA 3CRDA 2NZ7A 4D8OA 2P1HA 3CL3A 2MN4A 2A9IA 2MS7A 4E9MA 4IZAB 2YVIA 1WXPA 4QOBA 4I16A 2M5VA 2B1WA 2MPCA 2DBHA 1D2ZB 4A2WA 2OF5A 2D96A 3KATA 3LQRA 1E3YA 4F44A 4ZBWA 3YGSP 2HM2Q 2MB9A 1YGOA 2F1SA 3J6JA 2N1FA 3EZQB 3MOPA 4F42A 1A1WA 4A2QA 2KN6A 4M9SA 4EWIA 1A1ZA 2YQFA 1WH4A 2IB1A 3MOPK 1FADA 4N1KA 2N7ZA 2BBZA 1Z6TA 1DGNA 2N00A 2LWDA 2N80A 4JQWA 4M9ZA 3T6PA 4P4HI 1C15A 2KM6A 2LS7A 4P4HA 3YGSC 4DWNA 4RHWA 2YGSA 3LQQA 3QF2A 1UCPA 4N1JA 1WMGA 2NAQA 2YU0A 1CWWA 2N97A 3MOPG 2G7RA 2MS8A 4O9FA 2DBFA 2A5YB 4FH0A 2VGQA 2DBDA
chains in the Genus database with same CATH topology
1NGRA 2L9MA 2LWEA 4IZ5E 4NQKA 4JUPA 2XV9A 2O71A 1ICHA 2MJMA 4LWDA 4N1LA 1E41A 2GF5A 1DDFA 4O6XA 2DO9A 2N83A 4UZ0A 1N3KA 3EZQA 4O9LA 1PN5A 1CY5A 2NSNA 2BBRA 4M9XA 4O7QA 4IZ7B 4RHWE 2OF5H 3J63A 1D2ZA 2DBGA 2L6AA 3CRDA 2NZ7A 4D8OA 2P1HA 3CL3A 2MN4A 2A9IA 2MS7A 4E9MA 4IZAB 2YVIA 1WXPA 4QOBA 4I16A 2M5VA 2B1WA 2MPCA 2DBHA 1D2ZB 4A2WA 2OF5A 2D96A 3KATA 3LQRA 1E3YA 4F44A 4ZBWA 3YGSP 2HM2Q 2MB9A 1YGOA 2F1SA 3J6JA 2N1FA 3EZQB 3MOPA 4F42A 1A1WA 4A2QA 2KN6A 4M9SA 4EWIA 1A1ZA 2YQFA 1WH4A 2IB1A 3MOPK 1FADA 4N1KA 2N7ZA 2BBZA 1Z6TA 1DGNA 2N00A 2LWDA 2N80A 4JQWA 4M9ZA 3T6PA 4P4HI 1C15A 2KM6A 2LS7A 4P4HA 3YGSC 4DWNA 4RHWA 2YGSA 3LQQA 3QF2A 1UCPA 4N1JA 1WMGA 2NAQA 2YU0A 1CWWA 2N97A 3MOPG 2G7RA 2MS8A 4O9FA 2DBFA 2A5YB 4FH0A 2VGQA 2DBDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1NGR A;  2L9M A;  2LWE A;  4IZ5 E;  4NQK A;  4JUP A;  2O71 A;  1ICH A;  4LWD A;  4N1L A;  1E41 A;  2GF5 A;  1DDF A;  4O6X A;  2DO9 A;  2N83 A;  4UZ0 A;  1N3K A;  3EZQ A;  4O9L A;  1PN5 A;  1CY5 A;  2NSN A;  2BBR A;  4M9X A;  4O7Q A;  4IZ7 B;  4RHW E;  2OF5 H;  3J63 A;  1D2Z A;  2DBG A;  2L6A A;  3CRD A;  2NZ7 A;  4D8O A;  2P1H A;  3CL3 A;  2MN4 A;  2A9I A;  2MS7 A;  4E9M A;  4IZA B;  2YVI A;  1WXP A;  4QOB A;  4I16 A;  2M5V A;  2B1W A;  2MPC A;  2DBH A;  1D2Z B;  4A2W A;  2OF5 A;  2D96 A;  3KAT A;  3LQR A;  1E3Y A;  4F44 A;  4ZBW A;  3YGS P;  2HM2 Q;  2MB9 A;  1YGO A;  2F1S A;  3J6J A;  2N1F A;  3EZQ B;  3MOP A;  4F42 A;  1A1W A;  4A2Q A;  2KN6 A;  4M9S A;  4EWI A;  1A1Z A;  2YQF A;  1WH4 A;  2IB1 A;  3MOP K;  1FAD A;  4N1K A;  2N7Z A;  2BBZ A;  1Z6T A;  1DGN A;  2N00 A;  2LWD A;  2N80 A;  4JQW A;  4M9Z A;  3T6P A;  4P4H I;  1C15 A;  2KM6 A;  2LS7 A;  4P4H A;  3YGS C;  4DWN A;  4RHW A;  2YGS A;  3LQQ A;  3QF2 A;  1UCP A;  4N1J A;  1WMG A;  2NAQ A;  2YU0 A;  1CWW A;  2N97 A;  3MOP G;  2G7R A;  2MS8 A;  4O9F A;  2DBF A;  2A5Y B;  4FH0 A;  2VGQ A;  2DBD A; 
#chains in the Genus database with same CATH topology
 1NGR A;  2L9M A;  2LWE A;  4IZ5 E;  4NQK A;  4JUP A;  2XV9 A;  2O71 A;  1ICH A;  2MJM A;  4LWD A;  4N1L A;  1E41 A;  2GF5 A;  1DDF A;  4O6X A;  2DO9 A;  2N83 A;  4UZ0 A;  1N3K A;  3EZQ A;  4O9L A;  1PN5 A;  1CY5 A;  2NSN A;  2BBR A;  4M9X A;  4O7Q A;  4IZ7 B;  4RHW E;  2OF5 H;  3J63 A;  1D2Z A;  2DBG A;  2L6A A;  3CRD A;  2NZ7 A;  4D8O A;  2P1H A;  3CL3 A;  2MN4 A;  2A9I A;  2MS7 A;  4E9M A;  4IZA B;  2YVI A;  1WXP A;  4QOB A;  4I16 A;  2M5V A;  2B1W A;  2MPC A;  2DBH A;  1D2Z B;  4A2W A;  2OF5 A;  2D96 A;  3KAT A;  3LQR A;  1E3Y A;  4F44 A;  4ZBW A;  3YGS P;  2HM2 Q;  2MB9 A;  1YGO A;  2F1S A;  3J6J A;  2N1F A;  3EZQ B;  3MOP A;  4F42 A;  1A1W A;  4A2Q A;  2KN6 A;  4M9S A;  4EWI A;  1A1Z A;  2YQF A;  1WH4 A;  2IB1 A;  3MOP K;  1FAD A;  4N1K A;  2N7Z A;  2BBZ A;  1Z6T A;  1DGN A;  2N00 A;  2LWD A;  2N80 A;  4JQW A;  4M9Z A;  3T6P A;  4P4H I;  1C15 A;  2KM6 A;  2LS7 A;  4P4H A;  3YGS C;  4DWN A;  4RHW A;  2YGS A;  3LQQ A;  3QF2 A;  1UCP A;  4N1J A;  1WMG A;  2NAQ A;  2YU0 A;  1CWW A;  2N97 A;  3MOP G;  2G7R A;  2MS8 A;  4O9F A;  2DBF A;  2A5Y B;  4FH0 A;  2VGQ A;  2DBD A; 
#chains in the Genus database with same CATH homology
 1NGR A;  2L9M A;  2LWE A;  4IZ5 E;  4NQK A;  4JUP A;  2XV9 A;  2O71 A;  1ICH A;  2MJM A;  4LWD A;  4N1L A;  1E41 A;  2GF5 A;  1DDF A;  4O6X A;  2DO9 A;  2N83 A;  4UZ0 A;  1N3K A;  3EZQ A;  4O9L A;  1PN5 A;  1CY5 A;  2NSN A;  2BBR A;  4M9X A;  4O7Q A;  4IZ7 B;  4RHW E;  2OF5 H;  3J63 A;  1D2Z A;  2DBG A;  2L6A A;  3CRD A;  2NZ7 A;  4D8O A;  2P1H A;  3CL3 A;  2MN4 A;  2A9I A;  2MS7 A;  4E9M A;  4IZA B;  2YVI A;  1WXP A;  4QOB A;  4I16 A;  2M5V A;  2B1W A;  2MPC A;  2DBH A;  1D2Z B;  4A2W A;  2OF5 A;  2D96 A;  3KAT A;  3LQR A;  1E3Y A;  4F44 A;  4ZBW A;  3YGS P;  2HM2 Q;  2MB9 A;  1YGO A;  2F1S A;  3J6J A;  2N1F A;  3EZQ B;  3MOP A;  4F42 A;  1A1W A;  4A2Q A;  2KN6 A;  4M9S A;  4EWI A;  1A1Z A;  2YQF A;  1WH4 A;  2IB1 A;  3MOP K;  1FAD A;  4N1K A;  2N7Z A;  2BBZ A;  1Z6T A;  1DGN A;  2N00 A;  2LWD A;  2N80 A;  4JQW A;  4M9Z A;  3T6P A;  4P4H I;  1C15 A;  2KM6 A;  2LS7 A;  4P4H A;  3YGS C;  4DWN A;  4RHW A;  2YGS A;  3LQQ A;  3QF2 A;  1UCP A;  4N1J A;  1WMG A;  2NAQ A;  2YU0 A;  1CWW A;  2N97 A;  3MOP G;  2G7R A;  2MS8 A;  4O9F A;  2DBF A;  2A5Y B;  4FH0 A;  2VGQ A;  2DBD A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...