The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
27
|
sequence length |
91
|
structure length |
91
|
Chain Sequence |
SSSFFPDFGLLLYLEELNKEELNTFKLFLKETMEPEHGLTPWNEVKKARREDLANLMKKYYPGEKAWSVSLKIFGKMNLKDLCERAKEEIN
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| publication title |
Structures of the NLRP14 pyrin domain reveal a conformational switch mechanism regulating its molecular interactions.
pubmed doi rcsb |
| molecule tags |
Signaling protein
|
| source organism |
Homo sapiens
|
| molecule keywords |
NACHT, LRR and PYD domains-containing protein 14
|
| total genus |
27
|
| structure length |
91
|
| sequence length |
91
|
| chains with identical sequence |
B, C, D
|
| ec nomenclature | |
| pdb deposition date | 2013-10-04 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| A | PF02758 | PYRIN | PAAD/DAPIN/Pyrin domain |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Mainly Alpha | Orthogonal Bundle | Death Domain, Fas | Death Domain, Fas |
#chains in the Genus database with same CATH superfamily 3CRD A; 4QOB A; 2DO9 A; 2KN6 A; 2DBH A; 2N83 A; 4FH0 A; 4DWN A; 2A9I A; 3QF2 A; 1E3Y A; 4JQW A; 4N1K A; 4I16 A; 1PN5 A; 2KM6 A; 2IB1 A; 3CL3 A; 2HM2 Q; 2MS7 A; 4EWI A; 2YQF A; 3MOP G; 2G7R A; 2OF5 A; 2DBF A; 2MS8 A; 4O9F A; 1NGR A; 1YGO A; 3LQQ A; 2N80 A; 4IZ5 E; 4O9L A; 1Z6T A; 4O6X A; 1CY5 A; 4P4H A; 4A2W A; 4UZ0 A; 2OF5 H; 4M9Z A; 2DBD A; 2GF5 A; 4N1J A; 1ICH A; 2P1H A; 4M9X A; 2N7Z A; 1A1Z A; 4JUP A; 4LWD A; 3MOP K; 1UCP A; 4F42 A; 2D96 A; 4ZBW A; 1DDF A; 2LWD A; 2DBG A; 2YGS A; 4RHW E; 2YVI A; 2B1W A; 3YGS P; 4M9S A; 2N00 A; 4E9M A; 2BBZ A; 2LWE A; 3EZQ B; 3J6J A; 1WXP A; 1C15 A; 2NAQ A; 4RHW A; 2MPC A; 2N97 A; 2VGQ A; 4IZA B; 2O71 A; 2BBR A; 3T6P A; 4D8O A; 3YGS C; 3KAT A; 3EZQ A; 1N3K A; 1A1W A; 1D2Z B; 2LS7 A; 2L6A A; 3LQR A; 2A5Y B; 2MN4 A; 4N1L A; 4IZ7 B; 1WMG A; 4F44 A; 1CWW A; 4O7Q A; 1WH4 A; 4A2Q A; 2MB9 A; 2YU0 A; 4P4H I; 2NZ7 A; 3J63 A; 2F1S A; 2L9M A; 4NQK A; 2N1F A; 1DGN A; 1D2Z A; 1E41 A; 3MOP A; 1FAD A; 2M5V A; 2NSN A; #chains in the Genus database with same CATH topology 3CRD A; 2MJM A; 4QOB A; 2DO9 A; 2KN6 A; 2DBH A; 2N83 A; 4FH0 A; 4DWN A; 2A9I A; 3QF2 A; 1E3Y A; 4JQW A; 4N1K A; 4I16 A; 1PN5 A; 2KM6 A; 2IB1 A; 3CL3 A; 2HM2 Q; 2MS7 A; 4EWI A; 2XV9 A; 2YQF A; 3MOP G; 2G7R A; 2OF5 A; 2DBF A; 2MS8 A; 4O9F A; 1NGR A; 1YGO A; 3LQQ A; 2N80 A; 4IZ5 E; 4O9L A; 1Z6T A; 4O6X A; 1CY5 A; 4P4H A; 4A2W A; 4UZ0 A; 2OF5 H; 4M9Z A; 2DBD A; 2GF5 A; 4N1J A; 1ICH A; 2P1H A; 4M9X A; 2N7Z A; 1A1Z A; 4JUP A; 4LWD A; 3MOP K; 1UCP A; 4F42 A; 2D96 A; 4ZBW A; 1DDF A; 2LWD A; 2DBG A; 2YGS A; 4RHW E; 2YVI A; 2B1W A; 3YGS P; 4M9S A; 2N00 A; 4E9M A; 2BBZ A; 2LWE A; 3EZQ B; 3J6J A; 1WXP A; 1C15 A; 2NAQ A; 4RHW A; 2MPC A; 2N97 A; 2VGQ A; 4IZA B; 2O71 A; 2BBR A; 3T6P A; 4D8O A; 3YGS C; 3KAT A; 3EZQ A; 1N3K A; 1A1W A; 1D2Z B; 2LS7 A; 2L6A A; 3LQR A; 2A5Y B; 2MN4 A; 4N1L A; 4IZ7 B; 1WMG A; 4F44 A; 1CWW A; 4O7Q A; 1WH4 A; 4A2Q A; 2MB9 A; 2YU0 A; 4P4H I; 2NZ7 A; 3J63 A; 2F1S A; 2L9M A; 4NQK A; 2N1F A; 1DGN A; 1D2Z A; 1E41 A; 3MOP A; 1FAD A; 2M5V A; 2NSN A; #chains in the Genus database with same CATH homology 3CRD A; 2MJM A; 4QOB A; 2DO9 A; 2KN6 A; 2DBH A; 2N83 A; 4FH0 A; 4DWN A; 2A9I A; 3QF2 A; 1E3Y A; 4JQW A; 4N1K A; 4I16 A; 1PN5 A; 2KM6 A; 2IB1 A; 3CL3 A; 2HM2 Q; 2MS7 A; 4EWI A; 2XV9 A; 2YQF A; 3MOP G; 2G7R A; 2OF5 A; 2DBF A; 2MS8 A; 4O9F A; 1NGR A; 1YGO A; 3LQQ A; 2N80 A; 4IZ5 E; 4O9L A; 1Z6T A; 4O6X A; 1CY5 A; 4P4H A; 4A2W A; 4UZ0 A; 2OF5 H; 4M9Z A; 2DBD A; 2GF5 A; 4N1J A; 1ICH A; 2P1H A; 4M9X A; 2N7Z A; 1A1Z A; 4JUP A; 4LWD A; 3MOP K; 1UCP A; 4F42 A; 2D96 A; 4ZBW A; 1DDF A; 2LWD A; 2DBG A; 2YGS A; 4RHW E; 2YVI A; 2B1W A; 3YGS P; 4M9S A; 2N00 A; 4E9M A; 2BBZ A; 2LWE A; 3EZQ B; 3J6J A; 1WXP A; 1C15 A; 2NAQ A; 4RHW A; 2MPC A; 2N97 A; 2VGQ A; 4IZA B; 2O71 A; 2BBR A; 3T6P A; 4D8O A; 3YGS C; 3KAT A; 3EZQ A; 1N3K A; 1A1W A; 1D2Z B; 2LS7 A; 2L6A A; 3LQR A; 2A5Y B; 2MN4 A; 4N1L A; 4IZ7 B; 1WMG A; 4F44 A; 1CWW A; 4O7Q A; 1WH4 A; 4A2Q A; 2MB9 A; 2YU0 A; 4P4H I; 2NZ7 A; 3J63 A; 2F1S A; 2L9M A; 4NQK A; 2N1F A; 1DGN A; 1D2Z A; 1E41 A; 3MOP A; 1FAD A; 2M5V A; 2NSN A;
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