4P4HA

Caught-in-action signaling complex of rig-i 2card domain and mavs card domain
Total Genus 61
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
61
sequence length
188
structure length
188
Chain Sequence
MTTEQRRSLQAFQDYIRKTLDPTYILSYMAPWFREEEVQYIQAEKNNKGPMAAATLFLKFLLELQEEGWFRGFLDALDHAGYSGLYEAIESWDFKKIEKLEEYRLLLKRLQPEFKTRIIPTDIISDLSECLINQECEEILQICSTKGMMAGAEKLVECLLRSDKENWPKTLKLALEKERNKFSELWIV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Molecular Imprinting as a Signal-Activation Mechanism of the Viral RNA Sensor RIG-I.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords Probable ATP-dependent RNA helicase DDX58
total genus 61
structure length 188
sequence length 188
chains with identical sequence B, C, D, E, F, G, H
ec nomenclature ec 3.6.4.13: RNA helicase.
pdb deposition date 2014-03-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF16739 CARD_2 Caspase recruitment domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.533.10 Mainly Alpha Orthogonal Bundle Death Domain, Fas Death Domain, Fas 4p4hA01
1.10.533.10 Mainly Alpha Orthogonal Bundle Death Domain, Fas Death Domain, Fas 4p4hA02
2YGSA 2N7ZA 2MPCA 2VGQA 3T6PA 2A5YB 2MS7A 3KATA 4IZ7B 4JQWA 2YU0A 4O6XA 2NZ7A 1E3YA 2KN6A 2F1SA 2DO9A 2MS8A 4QOBA 2N1FA 2LWEA 3CRDA 4N1LA 3J6JA 2DBFA 4I16A 1YGOA 3MOPK 4JUPA 2M5VA 2KM6A 1Z6TA 4UZ0A 2MB9A 1WMGA 4O9LA 2BBZA 2LWDA 4M9SA 3J63A 3MOPG 4NQKA 4D8OA 4M9XA 3EZQB 2N80A 1FADA 2P1HA 2D96A 2N97A 1C15A 4DWNA 4RHWE 1ICHA 1D2ZA 4N1KA 4LWDA 4A2QA 4F44A 2LS7A 2DBDA 4P4HI 1UCPA 4IZ5E 4FH0A 2O71A 2NAQA 1WH4A 2OF5H 2L9MA 1DGNA 2YQFA 1PN5A 3CL3A 1D2ZB 3MOPA 4P4HA 2MN4A 2GF5A 4IZAB 4F42A 4M9ZA 1E41A 2HM2Q 1N3KA 2A9IA 1A1ZA 4ZBWA 3YGSP 2L6AA 4E9MA 3QF2A 1A1WA 2N00A 2DBHA 4O7QA 4N1JA 2DBGA 2B1WA 4A2WA 1CY5A 3LQQA 1CWWA 2OF5A 4RHWA 3EZQA 3YGSC 2BBRA 2YVIA 1WXPA 2G7RA 2N83A 4O9FA 3LQRA 1NGRA 2IB1A 4EWIA 2NSNA 1DDFA
chains in the Genus database with same CATH superfamily
2YGSA 2N7ZA 2MPCA 2VGQA 3T6PA 2A5YB 2MS7A 3KATA 4IZ7B 4JQWA 2YU0A 4O6XA 2NZ7A 1E3YA 2KN6A 2F1SA 2DO9A 2MS8A 4QOBA 2N1FA 2LWEA 3CRDA 4N1LA 3J6JA 2DBFA 4I16A 1YGOA 3MOPK 4JUPA 2M5VA 2KM6A 1Z6TA 4UZ0A 2MB9A 1WMGA 4O9LA 2BBZA 2LWDA 4M9SA 3J63A 3MOPG 4NQKA 4D8OA 4M9XA 3EZQB 2N80A 1FADA 2P1HA 2D96A 2N97A 1C15A 4DWNA 4RHWE 1ICHA 1D2ZA 4N1KA 4LWDA 4A2QA 4F44A 2LS7A 2DBDA 4P4HI 1UCPA 4IZ5E 4FH0A 2O71A 2NAQA 1WH4A 2OF5H 2L9MA 1DGNA 2YQFA 1PN5A 3CL3A 1D2ZB 3MOPA 4P4HA 2MN4A 2GF5A 4IZAB 4F42A 4M9ZA 1E41A 2HM2Q 1N3KA 2A9IA 1A1ZA 4ZBWA 3YGSP 2L6AA 4E9MA 3QF2A 1A1WA 2N00A 2DBHA 4O7QA 4N1JA 2DBGA 2MJMA 2B1WA 2XV9A 4A2WA 1CY5A 3LQQA 1CWWA 2OF5A 4RHWA 3EZQA 3YGSC 2BBRA 2YVIA 1WXPA 2G7RA 2N83A 4O9FA 3LQRA 1NGRA 2IB1A 4EWIA 2NSNA 1DDFA
chains in the Genus database with same CATH topology
2YGSA 2N7ZA 2MPCA 2VGQA 3T6PA 2A5YB 2MS7A 3KATA 4IZ7B 4JQWA 2YU0A 4O6XA 2NZ7A 1E3YA 2KN6A 2F1SA 2DO9A 2MS8A 4QOBA 2N1FA 2LWEA 3CRDA 4N1LA 3J6JA 2DBFA 4I16A 1YGOA 3MOPK 4JUPA 2M5VA 2KM6A 1Z6TA 4UZ0A 2MB9A 1WMGA 4O9LA 2BBZA 2LWDA 4M9SA 3J63A 3MOPG 4NQKA 4D8OA 4M9XA 3EZQB 2N80A 1FADA 2P1HA 2D96A 2N97A 1C15A 4DWNA 4RHWE 1ICHA 1D2ZA 4N1KA 4LWDA 4A2QA 4F44A 2LS7A 2DBDA 4P4HI 1UCPA 4IZ5E 4FH0A 2O71A 2NAQA 1WH4A 2OF5H 2L9MA 1DGNA 2YQFA 1PN5A 3CL3A 1D2ZB 3MOPA 4P4HA 2MN4A 2GF5A 4IZAB 4F42A 4M9ZA 1E41A 2HM2Q 1N3KA 2A9IA 1A1ZA 4ZBWA 3YGSP 2L6AA 4E9MA 3QF2A 1A1WA 2N00A 2DBHA 4O7QA 4N1JA 2DBGA 2MJMA 2B1WA 2XV9A 4A2WA 1CY5A 3LQQA 1CWWA 2OF5A 4RHWA 3EZQA 3YGSC 2BBRA 2YVIA 1WXPA 2G7RA 2N83A 4O9FA 3LQRA 1NGRA 2IB1A 4EWIA 2NSNA 1DDFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2YGS A;  2N7Z A;  2MPC A;  2VGQ A;  3T6P A;  2A5Y B;  2MS7 A;  3KAT A;  4IZ7 B;  4JQW A;  2YU0 A;  4O6X A;  2NZ7 A;  1E3Y A;  2KN6 A;  2F1S A;  2DO9 A;  2MS8 A;  4QOB A;  2N1F A;  2LWE A;  3CRD A;  4N1L A;  3J6J A;  2DBF A;  4I16 A;  1YGO A;  3MOP K;  4JUP A;  2M5V A;  2KM6 A;  1Z6T A;  4UZ0 A;  2MB9 A;  1WMG A;  4O9L A;  2BBZ A;  2LWD A;  4M9S A;  3J63 A;  3MOP G;  4NQK A;  4D8O A;  4M9X A;  3EZQ B;  2N80 A;  1FAD A;  2P1H A;  2D96 A;  2N97 A;  1C15 A;  4DWN A;  4RHW E;  1ICH A;  1D2Z A;  4N1K A;  4LWD A;  4A2Q A;  4F44 A;  2LS7 A;  2DBD A;  4P4H I;  1UCP A;  4IZ5 E;  4FH0 A;  2O71 A;  2NAQ A;  1WH4 A;  2OF5 H;  2L9M A;  1DGN A;  2YQF A;  1PN5 A;  3CL3 A;  1D2Z B;  3MOP A;  4P4H A;  2MN4 A;  2GF5 A;  4IZA B;  4F42 A;  4M9Z A;  1E41 A;  2HM2 Q;  1N3K A;  2A9I A;  1A1Z A;  4ZBW A;  3YGS P;  2L6A A;  4E9M A;  3QF2 A;  1A1W A;  2N00 A;  2DBH A;  4O7Q A;  4N1J A;  2DBG A;  2B1W A;  4A2W A;  1CY5 A;  3LQQ A;  1CWW A;  2OF5 A;  4RHW A;  3EZQ A;  3YGS C;  2BBR A;  2YVI A;  1WXP A;  2G7R A;  2N83 A;  4O9F A;  3LQR A;  1NGR A;  2IB1 A;  4EWI A;  2NSN A;  1DDF A; 
#chains in the Genus database with same CATH topology
 2YGS A;  2N7Z A;  2MPC A;  2VGQ A;  3T6P A;  2A5Y B;  2MS7 A;  3KAT A;  4IZ7 B;  4JQW A;  2YU0 A;  4O6X A;  2NZ7 A;  1E3Y A;  2KN6 A;  2F1S A;  2DO9 A;  2MS8 A;  4QOB A;  2N1F A;  2LWE A;  3CRD A;  4N1L A;  3J6J A;  2DBF A;  4I16 A;  1YGO A;  3MOP K;  4JUP A;  2M5V A;  2KM6 A;  1Z6T A;  4UZ0 A;  2MB9 A;  1WMG A;  4O9L A;  2BBZ A;  2LWD A;  4M9S A;  3J63 A;  3MOP G;  4NQK A;  4D8O A;  4M9X A;  3EZQ B;  2N80 A;  1FAD A;  2P1H A;  2D96 A;  2N97 A;  1C15 A;  4DWN A;  4RHW E;  1ICH A;  1D2Z A;  4N1K A;  4LWD A;  4A2Q A;  4F44 A;  2LS7 A;  2DBD A;  4P4H I;  1UCP A;  4IZ5 E;  4FH0 A;  2O71 A;  2NAQ A;  1WH4 A;  2OF5 H;  2L9M A;  1DGN A;  2YQF A;  1PN5 A;  3CL3 A;  1D2Z B;  3MOP A;  4P4H A;  2MN4 A;  2GF5 A;  4IZA B;  4F42 A;  4M9Z A;  1E41 A;  2HM2 Q;  1N3K A;  2A9I A;  1A1Z A;  4ZBW A;  3YGS P;  2L6A A;  4E9M A;  3QF2 A;  1A1W A;  2N00 A;  2DBH A;  4O7Q A;  4N1J A;  2DBG A;  2MJM A;  2B1W A;  2XV9 A;  4A2W A;  1CY5 A;  3LQQ A;  1CWW A;  2OF5 A;  4RHW A;  3EZQ A;  3YGS C;  2BBR A;  2YVI A;  1WXP A;  2G7R A;  2N83 A;  4O9F A;  3LQR A;  1NGR A;  2IB1 A;  4EWI A;  2NSN A;  1DDF A; 
#chains in the Genus database with same CATH homology
 2YGS A;  2N7Z A;  2MPC A;  2VGQ A;  3T6P A;  2A5Y B;  2MS7 A;  3KAT A;  4IZ7 B;  4JQW A;  2YU0 A;  4O6X A;  2NZ7 A;  1E3Y A;  2KN6 A;  2F1S A;  2DO9 A;  2MS8 A;  4QOB A;  2N1F A;  2LWE A;  3CRD A;  4N1L A;  3J6J A;  2DBF A;  4I16 A;  1YGO A;  3MOP K;  4JUP A;  2M5V A;  2KM6 A;  1Z6T A;  4UZ0 A;  2MB9 A;  1WMG A;  4O9L A;  2BBZ A;  2LWD A;  4M9S A;  3J63 A;  3MOP G;  4NQK A;  4D8O A;  4M9X A;  3EZQ B;  2N80 A;  1FAD A;  2P1H A;  2D96 A;  2N97 A;  1C15 A;  4DWN A;  4RHW E;  1ICH A;  1D2Z A;  4N1K A;  4LWD A;  4A2Q A;  4F44 A;  2LS7 A;  2DBD A;  4P4H I;  1UCP A;  4IZ5 E;  4FH0 A;  2O71 A;  2NAQ A;  1WH4 A;  2OF5 H;  2L9M A;  1DGN A;  2YQF A;  1PN5 A;  3CL3 A;  1D2Z B;  3MOP A;  4P4H A;  2MN4 A;  2GF5 A;  4IZA B;  4F42 A;  4M9Z A;  1E41 A;  2HM2 Q;  1N3K A;  2A9I A;  1A1Z A;  4ZBW A;  3YGS P;  2L6A A;  4E9M A;  3QF2 A;  1A1W A;  2N00 A;  2DBH A;  4O7Q A;  4N1J A;  2DBG A;  2MJM A;  2B1W A;  2XV9 A;  4A2W A;  1CY5 A;  3LQQ A;  1CWW A;  2OF5 A;  4RHW A;  3EZQ A;  3YGS C;  2BBR A;  2YVI A;  1WXP A;  2G7R A;  2N83 A;  4O9F A;  3LQR A;  1NGR A;  2IB1 A;  4EWI A;  2NSN A;  1DDF A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...