4QOBA

Crystal structure of cpop1
Total Genus 34
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
34
sequence length
87
structure length
87
Chain Sequence
TKREAILKVLENLTPEELKKFKMKLGTVPLREGFERIPRGALGQLDIVDLTDKLVASYYEDYAAELVVAVLRDMRMLEEAARLQRAA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of cPOP1
rcsb
molecule tags Protein binding
source organism Homo sapiens
molecule keywords Pyrin domain-containing protein 1
total genus 34
structure length 87
sequence length 87
chains with identical sequence B
ec nomenclature
pdb deposition date 2014-06-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02758 PYRIN PAAD/DAPIN/Pyrin domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.533.10 Mainly Alpha Orthogonal Bundle Death Domain, Fas Death Domain, Fas 4qobA00
2KN6A 4RHWA 3LQRA 1Z6TA 1NGRA 4A2WA 1A1ZA 2LS7A 4JQWA 4ZBWA 4N1KA 2DBFA 2LWDA 4E9MA 2NZ7A 4IZ7B 1WH4A 3CRDA 4P4HI 4UZ0A 4M9ZA 2G7RA 2N00A 2B1WA 1CWWA 2MS7A 2N80A 2DBHA 1E3YA 2LWEA 4F42A 1UCPA 4LWDA 2M5VA 4QOBA 3YGSC 1FADA 1YGOA 2YU0A 1D2ZB 2BBZA 2IB1A 1C15A 2OF5A 4O6XA 1N3KA 2A9IA 4O9LA 4EWIA 2YVIA 2F1SA 2DBDA 4JUPA 2L9MA 1PN5A 1E41A 2MN4A 4NQKA 2L6AA 4A2QA 1DGNA 1D2ZA 4M9XA 2D96A 2DBGA 4FH0A 2NSNA 4RHWE 2GF5A 4IZ5E 2KM6A 4F44A 2HM2Q 3EZQA 3MOPK 2NAQA 3YGSP 2N1FA 1CY5A 4DWNA 2N97A 2P1HA 3EZQB 2DO9A 4O9FA 3KATA 3QF2A 3J6JA 1WXPA 2YGSA 3CL3A 1ICHA 2O71A 4N1LA 2VGQA 4M9SA 4O7QA 4D8OA 2A5YB 2N83A 2N7ZA 4N1JA 1A1WA 3LQQA 1WMGA 2YQFA 3MOPG 3MOPA 2BBRA 2OF5H 4I16A 2MPCA 3J63A 3T6PA 1DDFA 4IZAB 2MB9A 2MS8A 4P4HA
chains in the Genus database with same CATH superfamily
2KN6A 4RHWA 3LQRA 1Z6TA 1NGRA 4A2WA 1A1ZA 2LS7A 4JQWA 4ZBWA 4N1KA 2DBFA 2LWDA 4E9MA 2NZ7A 4IZ7B 1WH4A 3CRDA 4P4HI 4UZ0A 4M9ZA 2G7RA 2N00A 2B1WA 1CWWA 2MS7A 2N80A 2DBHA 1E3YA 2MJMA 2LWEA 4F42A 1UCPA 4LWDA 2M5VA 4QOBA 3YGSC 1FADA 1YGOA 2YU0A 1D2ZB 2BBZA 2IB1A 1C15A 2OF5A 4O6XA 1N3KA 2A9IA 4O9LA 4EWIA 2YVIA 2F1SA 2DBDA 4JUPA 2L9MA 1PN5A 1E41A 2MN4A 4NQKA 2L6AA 4A2QA 1DGNA 1D2ZA 4M9XA 2D96A 2DBGA 4FH0A 2NSNA 4RHWE 2GF5A 4IZ5E 2KM6A 4F44A 2HM2Q 3EZQA 3MOPK 2NAQA 3YGSP 2N1FA 1CY5A 4DWNA 2N97A 2P1HA 3EZQB 2DO9A 4O9FA 3KATA 3QF2A 3J6JA 1WXPA 2YGSA 3CL3A 1ICHA 2XV9A 2O71A 4N1LA 2VGQA 4M9SA 4O7QA 4D8OA 2A5YB 2N83A 2N7ZA 4N1JA 1A1WA 3LQQA 1WMGA 2YQFA 3MOPG 3MOPA 2BBRA 2OF5H 4I16A 2MPCA 3J63A 3T6PA 1DDFA 4IZAB 2MB9A 2MS8A 4P4HA
chains in the Genus database with same CATH topology
2KN6A 4RHWA 3LQRA 1Z6TA 1NGRA 4A2WA 1A1ZA 2LS7A 4JQWA 4ZBWA 4N1KA 2DBFA 2LWDA 4E9MA 2NZ7A 4IZ7B 1WH4A 3CRDA 4P4HI 4UZ0A 4M9ZA 2G7RA 2N00A 2B1WA 1CWWA 2MS7A 2N80A 2DBHA 1E3YA 2MJMA 2LWEA 4F42A 1UCPA 4LWDA 2M5VA 4QOBA 3YGSC 1FADA 1YGOA 2YU0A 1D2ZB 2BBZA 2IB1A 1C15A 2OF5A 4O6XA 1N3KA 2A9IA 4O9LA 4EWIA 2YVIA 2F1SA 2DBDA 4JUPA 2L9MA 1PN5A 1E41A 2MN4A 4NQKA 2L6AA 4A2QA 1DGNA 1D2ZA 4M9XA 2D96A 2DBGA 4FH0A 2NSNA 4RHWE 2GF5A 4IZ5E 2KM6A 4F44A 2HM2Q 3EZQA 3MOPK 2NAQA 3YGSP 2N1FA 1CY5A 4DWNA 2N97A 2P1HA 3EZQB 2DO9A 4O9FA 3KATA 3QF2A 3J6JA 1WXPA 2YGSA 3CL3A 1ICHA 2XV9A 2O71A 4N1LA 2VGQA 4M9SA 4O7QA 4D8OA 2A5YB 2N83A 2N7ZA 4N1JA 1A1WA 3LQQA 1WMGA 2YQFA 3MOPG 3MOPA 2BBRA 2OF5H 4I16A 2MPCA 3J63A 3T6PA 1DDFA 4IZAB 2MB9A 2MS8A 4P4HA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2KN6 A;  4RHW A;  3LQR A;  1Z6T A;  1NGR A;  4A2W A;  1A1Z A;  2LS7 A;  4JQW A;  4ZBW A;  4N1K A;  2DBF A;  2LWD A;  4E9M A;  2NZ7 A;  4IZ7 B;  1WH4 A;  3CRD A;  4P4H I;  4UZ0 A;  4M9Z A;  2G7R A;  2N00 A;  2B1W A;  1CWW A;  2MS7 A;  2N80 A;  2DBH A;  1E3Y A;  2LWE A;  4F42 A;  1UCP A;  4LWD A;  2M5V A;  4QOB A;  3YGS C;  1FAD A;  1YGO A;  2YU0 A;  1D2Z B;  2BBZ A;  2IB1 A;  1C15 A;  2OF5 A;  4O6X A;  1N3K A;  2A9I A;  4O9L A;  4EWI A;  2YVI A;  2F1S A;  2DBD A;  4JUP A;  2L9M A;  1PN5 A;  1E41 A;  2MN4 A;  4NQK A;  2L6A A;  4A2Q A;  1DGN A;  1D2Z A;  4M9X A;  2D96 A;  2DBG A;  4FH0 A;  2NSN A;  4RHW E;  2GF5 A;  4IZ5 E;  2KM6 A;  4F44 A;  2HM2 Q;  3EZQ A;  3MOP K;  2NAQ A;  3YGS P;  2N1F A;  1CY5 A;  4DWN A;  2N97 A;  2P1H A;  3EZQ B;  2DO9 A;  4O9F A;  3KAT A;  3QF2 A;  3J6J A;  1WXP A;  2YGS A;  3CL3 A;  1ICH A;  2O71 A;  4N1L A;  2VGQ A;  4M9S A;  4O7Q A;  4D8O A;  2A5Y B;  2N83 A;  2N7Z A;  4N1J A;  1A1W A;  3LQQ A;  1WMG A;  2YQF A;  3MOP G;  3MOP A;  2BBR A;  2OF5 H;  4I16 A;  2MPC A;  3J63 A;  3T6P A;  1DDF A;  4IZA B;  2MB9 A;  2MS8 A;  4P4H A; 
#chains in the Genus database with same CATH topology
 2KN6 A;  4RHW A;  3LQR A;  1Z6T A;  1NGR A;  4A2W A;  1A1Z A;  2LS7 A;  4JQW A;  4ZBW A;  4N1K A;  2DBF A;  2LWD A;  4E9M A;  2NZ7 A;  4IZ7 B;  1WH4 A;  3CRD A;  4P4H I;  4UZ0 A;  4M9Z A;  2G7R A;  2N00 A;  2B1W A;  1CWW A;  2MS7 A;  2N80 A;  2DBH A;  1E3Y A;  2MJM A;  2LWE A;  4F42 A;  1UCP A;  4LWD A;  2M5V A;  4QOB A;  3YGS C;  1FAD A;  1YGO A;  2YU0 A;  1D2Z B;  2BBZ A;  2IB1 A;  1C15 A;  2OF5 A;  4O6X A;  1N3K A;  2A9I A;  4O9L A;  4EWI A;  2YVI A;  2F1S A;  2DBD A;  4JUP A;  2L9M A;  1PN5 A;  1E41 A;  2MN4 A;  4NQK A;  2L6A A;  4A2Q A;  1DGN A;  1D2Z A;  4M9X A;  2D96 A;  2DBG A;  4FH0 A;  2NSN A;  4RHW E;  2GF5 A;  4IZ5 E;  2KM6 A;  4F44 A;  2HM2 Q;  3EZQ A;  3MOP K;  2NAQ A;  3YGS P;  2N1F A;  1CY5 A;  4DWN A;  2N97 A;  2P1H A;  3EZQ B;  2DO9 A;  4O9F A;  3KAT A;  3QF2 A;  3J6J A;  1WXP A;  2YGS A;  3CL3 A;  1ICH A;  2XV9 A;  2O71 A;  4N1L A;  2VGQ A;  4M9S A;  4O7Q A;  4D8O A;  2A5Y B;  2N83 A;  2N7Z A;  4N1J A;  1A1W A;  3LQQ A;  1WMG A;  2YQF A;  3MOP G;  3MOP A;  2BBR A;  2OF5 H;  4I16 A;  2MPC A;  3J63 A;  3T6P A;  1DDF A;  4IZA B;  2MB9 A;  2MS8 A;  4P4H A; 
#chains in the Genus database with same CATH homology
 2KN6 A;  4RHW A;  3LQR A;  1Z6T A;  1NGR A;  4A2W A;  1A1Z A;  2LS7 A;  4JQW A;  4ZBW A;  4N1K A;  2DBF A;  2LWD A;  4E9M A;  2NZ7 A;  4IZ7 B;  1WH4 A;  3CRD A;  4P4H I;  4UZ0 A;  4M9Z A;  2G7R A;  2N00 A;  2B1W A;  1CWW A;  2MS7 A;  2N80 A;  2DBH A;  1E3Y A;  2MJM A;  2LWE A;  4F42 A;  1UCP A;  4LWD A;  2M5V A;  4QOB A;  3YGS C;  1FAD A;  1YGO A;  2YU0 A;  1D2Z B;  2BBZ A;  2IB1 A;  1C15 A;  2OF5 A;  4O6X A;  1N3K A;  2A9I A;  4O9L A;  4EWI A;  2YVI A;  2F1S A;  2DBD A;  4JUP A;  2L9M A;  1PN5 A;  1E41 A;  2MN4 A;  4NQK A;  2L6A A;  4A2Q A;  1DGN A;  1D2Z A;  4M9X A;  2D96 A;  2DBG A;  4FH0 A;  2NSN A;  4RHW E;  2GF5 A;  4IZ5 E;  2KM6 A;  4F44 A;  2HM2 Q;  3EZQ A;  3MOP K;  2NAQ A;  3YGS P;  2N1F A;  1CY5 A;  4DWN A;  2N97 A;  2P1H A;  3EZQ B;  2DO9 A;  4O9F A;  3KAT A;  3QF2 A;  3J6J A;  1WXP A;  2YGS A;  3CL3 A;  1ICH A;  2XV9 A;  2O71 A;  4N1L A;  2VGQ A;  4M9S A;  4O7Q A;  4D8O A;  2A5Y B;  2N83 A;  2N7Z A;  4N1J A;  1A1W A;  3LQQ A;  1WMG A;  2YQF A;  3MOP G;  3MOP A;  2BBR A;  2OF5 H;  4I16 A;  2MPC A;  3J63 A;  3T6P A;  1DDF A;  4IZA B;  2MB9 A;  2MS8 A;  4P4H A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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