4E9MA

Nod1 card domain with three disulfide-clinched, domain-swapped dimers in the asymmetric unit
Total Genus 37
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
37
sequence length
97
structure length
97
Chain Sequence
SESHPHIQLLKSNRELLVTHIRNTQCLVDNLLKNDYFSAEDAEIVCACPTQPDKVRKILDLVQSKGEEVSEFFLYLLQQLADAYVDLRPWLLEIGFS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of nod1 card domain with three disulfide-clinched, domain-swapped dimers in the asymmetric unit
rcsb
molecule tags Protein binding
source organism Homo sapiens
molecule keywords Nucleotide-binding oligomerization domain-containing protein
total genus 37
structure length 97
sequence length 97
chains with identical sequence B, C, D, E, F
ec nomenclature
pdb deposition date 2012-03-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00619 CARD Caspase recruitment domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.533.10 Mainly Alpha Orthogonal Bundle Death Domain, Fas Death Domain, Fas 4e9mA00
4LWDA 3YGSP 1DDFA 4N1LA 2L9MA 2KM6A 3MOPA 4QOBA 2D96A 2N00A 2M5VA 3CL3A 4IZAB 2N97A 2YVIA 3J63A 2DBDA 2P1HA 2NAQA 4I16A 2N80A 4P4HA 3QF2A 2DBHA 2MPCA 2N83A 4N1KA 4JUPA 4O6XA 1CY5A 3LQRA 3MOPK 2BBZA 2MN4A 1WXPA 4M9ZA 2F1SA 2L6AA 1D2ZA 4EWIA 2B1WA 3EZQA 4FH0A 2A5YB 2G7RA 2IB1A 2LWDA 4A2WA 4DWNA 3J6JA 2OF5H 4P4HI 4RHWA 4RHWE 2GF5A 2YU0A 2NSNA 1CWWA 2HM2Q 4M9XA 3T6PA 1D2ZB 2O71A 4UZ0A 3EZQB 4M9SA 1YGOA 1A1ZA 1C15A 4NQKA 1ICHA 4E9MA 2DBGA 3KATA 2MB9A 4F42A 3LQQA 4O9LA 2MS8A 4O7QA 4D8OA 4IZ5E 3CRDA 2LWEA 1WMGA 4IZ7B 2BBRA 1PN5A 1FADA 2LS7A 2DBFA 2YGSA 1E3YA 1DGNA 2A9IA 2N7ZA 4N1JA 2NZ7A 4JQWA 4O9FA 4A2QA 1WH4A 4F44A 4ZBWA 2KN6A 3MOPG 2DO9A 1NGRA 2VGQA 2N1FA 1N3KA 1A1WA 2MS7A 1E41A 1UCPA 1Z6TA 3YGSC 2YQFA 2OF5A
chains in the Genus database with same CATH superfamily
4LWDA 3YGSP 1DDFA 4N1LA 2L9MA 2KM6A 3MOPA 4QOBA 2D96A 2N00A 2M5VA 3CL3A 4IZAB 2N97A 2YVIA 3J63A 2DBDA 2P1HA 2NAQA 4I16A 2N80A 4P4HA 3QF2A 2DBHA 2MPCA 2XV9A 2N83A 4N1KA 4JUPA 4O6XA 1CY5A 3LQRA 3MOPK 2BBZA 2MN4A 1WXPA 4M9ZA 2F1SA 2L6AA 1D2ZA 4EWIA 2B1WA 3EZQA 4FH0A 2A5YB 2G7RA 2IB1A 2LWDA 4A2WA 4DWNA 3J6JA 2OF5H 4P4HI 4RHWA 4RHWE 2GF5A 2YU0A 2NSNA 1CWWA 2HM2Q 4M9XA 3T6PA 1D2ZB 2O71A 4UZ0A 3EZQB 4M9SA 1YGOA 1A1ZA 1C15A 4NQKA 1ICHA 4E9MA 2DBGA 3KATA 2MB9A 4F42A 3LQQA 4O9LA 2MS8A 4O7QA 4D8OA 4IZ5E 3CRDA 2LWEA 1WMGA 4IZ7B 2BBRA 1PN5A 1FADA 2LS7A 2DBFA 2YGSA 1E3YA 1DGNA 2A9IA 2N7ZA 4N1JA 2NZ7A 4JQWA 4O9FA 4A2QA 1WH4A 4F44A 4ZBWA 2KN6A 3MOPG 2DO9A 1NGRA 2VGQA 2N1FA 1N3KA 1A1WA 2MS7A 1E41A 1UCPA 1Z6TA 2MJMA 3YGSC 2YQFA 2OF5A
chains in the Genus database with same CATH topology
4LWDA 3YGSP 1DDFA 4N1LA 2L9MA 2KM6A 3MOPA 4QOBA 2D96A 2N00A 2M5VA 3CL3A 4IZAB 2N97A 2YVIA 3J63A 2DBDA 2P1HA 2NAQA 4I16A 2N80A 4P4HA 3QF2A 2DBHA 2MPCA 2XV9A 2N83A 4N1KA 4JUPA 4O6XA 1CY5A 3LQRA 3MOPK 2BBZA 2MN4A 1WXPA 4M9ZA 2F1SA 2L6AA 1D2ZA 4EWIA 2B1WA 3EZQA 4FH0A 2A5YB 2G7RA 2IB1A 2LWDA 4A2WA 4DWNA 3J6JA 2OF5H 4P4HI 4RHWA 4RHWE 2GF5A 2YU0A 2NSNA 1CWWA 2HM2Q 4M9XA 3T6PA 1D2ZB 2O71A 4UZ0A 3EZQB 4M9SA 1YGOA 1A1ZA 1C15A 4NQKA 1ICHA 4E9MA 2DBGA 3KATA 2MB9A 4F42A 3LQQA 4O9LA 2MS8A 4O7QA 4D8OA 4IZ5E 3CRDA 2LWEA 1WMGA 4IZ7B 2BBRA 1PN5A 1FADA 2LS7A 2DBFA 2YGSA 1E3YA 1DGNA 2A9IA 2N7ZA 4N1JA 2NZ7A 4JQWA 4O9FA 4A2QA 1WH4A 4F44A 4ZBWA 2KN6A 3MOPG 2DO9A 1NGRA 2VGQA 2N1FA 1N3KA 1A1WA 2MS7A 1E41A 1UCPA 1Z6TA 2MJMA 3YGSC 2YQFA 2OF5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4LWD A;  3YGS P;  1DDF A;  4N1L A;  2L9M A;  2KM6 A;  3MOP A;  4QOB A;  2D96 A;  2N00 A;  2M5V A;  3CL3 A;  4IZA B;  2N97 A;  2YVI A;  3J63 A;  2DBD A;  2P1H A;  2NAQ A;  4I16 A;  2N80 A;  4P4H A;  3QF2 A;  2DBH A;  2MPC A;  2N83 A;  4N1K A;  4JUP A;  4O6X A;  1CY5 A;  3LQR A;  3MOP K;  2BBZ A;  2MN4 A;  1WXP A;  4M9Z A;  2F1S A;  2L6A A;  1D2Z A;  4EWI A;  2B1W A;  3EZQ A;  4FH0 A;  2A5Y B;  2G7R A;  2IB1 A;  2LWD A;  4A2W A;  4DWN A;  3J6J A;  2OF5 H;  4P4H I;  4RHW A;  4RHW E;  2GF5 A;  2YU0 A;  2NSN A;  1CWW A;  2HM2 Q;  4M9X A;  3T6P A;  1D2Z B;  2O71 A;  4UZ0 A;  3EZQ B;  4M9S A;  1YGO A;  1A1Z A;  1C15 A;  4NQK A;  1ICH A;  4E9M A;  2DBG A;  3KAT A;  2MB9 A;  4F42 A;  3LQQ A;  4O9L A;  2MS8 A;  4O7Q A;  4D8O A;  4IZ5 E;  3CRD A;  2LWE A;  1WMG A;  4IZ7 B;  2BBR A;  1PN5 A;  1FAD A;  2LS7 A;  2DBF A;  2YGS A;  1E3Y A;  1DGN A;  2A9I A;  2N7Z A;  4N1J A;  2NZ7 A;  4JQW A;  4O9F A;  4A2Q A;  1WH4 A;  4F44 A;  4ZBW A;  2KN6 A;  3MOP G;  2DO9 A;  1NGR A;  2VGQ A;  2N1F A;  1N3K A;  1A1W A;  2MS7 A;  1E41 A;  1UCP A;  1Z6T A;  3YGS C;  2YQF A;  2OF5 A; 
#chains in the Genus database with same CATH topology
 4LWD A;  3YGS P;  1DDF A;  4N1L A;  2L9M A;  2KM6 A;  3MOP A;  4QOB A;  2D96 A;  2N00 A;  2M5V A;  3CL3 A;  4IZA B;  2N97 A;  2YVI A;  3J63 A;  2DBD A;  2P1H A;  2NAQ A;  4I16 A;  2N80 A;  4P4H A;  3QF2 A;  2DBH A;  2MPC A;  2XV9 A;  2N83 A;  4N1K A;  4JUP A;  4O6X A;  1CY5 A;  3LQR A;  3MOP K;  2BBZ A;  2MN4 A;  1WXP A;  4M9Z A;  2F1S A;  2L6A A;  1D2Z A;  4EWI A;  2B1W A;  3EZQ A;  4FH0 A;  2A5Y B;  2G7R A;  2IB1 A;  2LWD A;  4A2W A;  4DWN A;  3J6J A;  2OF5 H;  4P4H I;  4RHW A;  4RHW E;  2GF5 A;  2YU0 A;  2NSN A;  1CWW A;  2HM2 Q;  4M9X A;  3T6P A;  1D2Z B;  2O71 A;  4UZ0 A;  3EZQ B;  4M9S A;  1YGO A;  1A1Z A;  1C15 A;  4NQK A;  1ICH A;  4E9M A;  2DBG A;  3KAT A;  2MB9 A;  4F42 A;  3LQQ A;  4O9L A;  2MS8 A;  4O7Q A;  4D8O A;  4IZ5 E;  3CRD A;  2LWE A;  1WMG A;  4IZ7 B;  2BBR A;  1PN5 A;  1FAD A;  2LS7 A;  2DBF A;  2YGS A;  1E3Y A;  1DGN A;  2A9I A;  2N7Z A;  4N1J A;  2NZ7 A;  4JQW A;  4O9F A;  4A2Q A;  1WH4 A;  4F44 A;  4ZBW A;  2KN6 A;  3MOP G;  2DO9 A;  1NGR A;  2VGQ A;  2N1F A;  1N3K A;  1A1W A;  2MS7 A;  1E41 A;  1UCP A;  1Z6T A;  2MJM A;  3YGS C;  2YQF A;  2OF5 A; 
#chains in the Genus database with same CATH homology
 4LWD A;  3YGS P;  1DDF A;  4N1L A;  2L9M A;  2KM6 A;  3MOP A;  4QOB A;  2D96 A;  2N00 A;  2M5V A;  3CL3 A;  4IZA B;  2N97 A;  2YVI A;  3J63 A;  2DBD A;  2P1H A;  2NAQ A;  4I16 A;  2N80 A;  4P4H A;  3QF2 A;  2DBH A;  2MPC A;  2XV9 A;  2N83 A;  4N1K A;  4JUP A;  4O6X A;  1CY5 A;  3LQR A;  3MOP K;  2BBZ A;  2MN4 A;  1WXP A;  4M9Z A;  2F1S A;  2L6A A;  1D2Z A;  4EWI A;  2B1W A;  3EZQ A;  4FH0 A;  2A5Y B;  2G7R A;  2IB1 A;  2LWD A;  4A2W A;  4DWN A;  3J6J A;  2OF5 H;  4P4H I;  4RHW A;  4RHW E;  2GF5 A;  2YU0 A;  2NSN A;  1CWW A;  2HM2 Q;  4M9X A;  3T6P A;  1D2Z B;  2O71 A;  4UZ0 A;  3EZQ B;  4M9S A;  1YGO A;  1A1Z A;  1C15 A;  4NQK A;  1ICH A;  4E9M A;  2DBG A;  3KAT A;  2MB9 A;  4F42 A;  3LQQ A;  4O9L A;  2MS8 A;  4O7Q A;  4D8O A;  4IZ5 E;  3CRD A;  2LWE A;  1WMG A;  4IZ7 B;  2BBR A;  1PN5 A;  1FAD A;  2LS7 A;  2DBF A;  2YGS A;  1E3Y A;  1DGN A;  2A9I A;  2N7Z A;  4N1J A;  2NZ7 A;  4JQW A;  4O9F A;  4A2Q A;  1WH4 A;  4F44 A;  4ZBW A;  2KN6 A;  3MOP G;  2DO9 A;  1NGR A;  2VGQ A;  2N1F A;  1N3K A;  1A1W A;  2MS7 A;  1E41 A;  1UCP A;  1Z6T A;  2MJM A;  3YGS C;  2YQF A;  2OF5 A; 
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similar chains in the pdb database (?% sequence similarity)

 
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