1CXWA

The second type ii module from human matrix metalloproteinase 2
Total Genus 17
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
17
sequence length
60
structure length
60
Chain Sequence
TALFTMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The second type II module from human matrix metalloproteinase 2: structure, function and dynamics.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords HUMAN MATRIX METALLOPROTEINASE 2
total genus 17
structure length 60
sequence length 60
ec nomenclature ec 3.4.24.24: Gelatinase A.
pdb deposition date 1999-08-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00040 fn2 Fibronectin type II domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.10.10 Mainly Beta Ribbon Seminal Fluid Protein PDC-109 (Domain B) Fibronectin, type II, collagen-binding 1cxwA00
1J7MA 1CK7A 1EAKA 3MQLA 1L6JA 2FN2A 2V5OA 1GXDA 1E8BA 1PDCA 3M7PA 1E88A 1KS0A 1H8PA 1CXWA 1QO6A
chains in the Genus database with same CATH superfamily
2Y2KA 1O6IA 3HONA 1L6JA 1H0GA 1YU0A 1E6ZA 1GXDA 4IJFA 4MB4A 1CK7A 2Y2GA 1YU1A 4IJEA 1E6PA 3L2AA 2V5OA 4NZ4A 4LG2A 4OUIA 1ED7A 4OJOA 2IOUA 4TX8A 1AIWA 4MB5A 1GPFA 3L28A 1UR9A 4Z2LA 2XD1A 4OJLA 3WD4A 3WD1A 3WD3A 4HMEA 1UR8A 2Y2IA 3L25A 1CXWA 1PDCA 4NZ1A 4NZ3A 4Z2KA 3FKEA 2FN2A 2Y2JA 1YU3A 4Z2JA 1QO6A 2XD5A 2Y2OA 1W1VA 4IBIA 1E6NA 4IBBA 3L26A 4GHAA 2RTSA 3L29A 1YU4A 3KS4A 4IBKA 3M7PA 2FFFB 4IBGA 1H0IA 5BPVA 4NY2A 2JE5A 1KS0A 1YUEA 2Y2HA 1W1PA 2Y2QA 4OJ6A 1GOIA 3N3FA 1YU2A 4NYUA 2Y2MA 4Z2GA 1E6RA 2UWXA 1EAKA 4IBJA 1H8PA 4IBFA 3KS8A 2Y2NA 4HMCA 4GHLA 2BG1A 1E15A 4HMDA 4OJPA 1W1TA 1E88A 1OGGA 4GH9A 3WD0A 4Z2IA 2D49A 4IBCA 4NZ5A 4MB3A 3WD2A 2JCHA 1OGBA 3WX7A 1J7MA 2Y2PA 2Y2LA 3L27A 4Z2HA 4QNLA 3HSHA 3MQLA 1W1YA 4IBEA 4NYYA 1E8BA 4OJ5A 4IBDA
chains in the Genus database with same CATH topology
1J7MA 1CK7A 1EAKA 3MQLA 1L6JA 2FN2A 2V5OA 1GXDA 1E8BA 1PDCA 3M7PA 1E88A 1KS0A 1H8PA 1CXWA 1QO6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1J7M A;  1CK7 A;  1EAK A;  3MQL A;  1L6J A;  2FN2 A;  2V5O A;  1GXD A;  1E8B A;  1PDC A;  3M7P A;  1E88 A;  1KS0 A;  1H8P A;  1CXW A;  1QO6 A; 
#chains in the Genus database with same CATH topology
 2Y2K A;  1O6I A;  3HON A;  1L6J A;  1H0G A;  1YU0 A;  1E6Z A;  1GXD A;  4IJF A;  4MB4 A;  1CK7 A;  2Y2G A;  1YU1 A;  4IJE A;  1E6P A;  3L2A A;  2V5O A;  4NZ4 A;  4LG2 A;  4OUI A;  1ED7 A;  4OJO A;  2IOU A;  4TX8 A;  1AIW A;  4MB5 A;  1GPF A;  3L28 A;  1UR9 A;  4Z2L A;  2XD1 A;  4OJL A;  3WD4 A;  3WD1 A;  3WD3 A;  4HME A;  1UR8 A;  2Y2I A;  3L25 A;  1CXW A;  1PDC A;  4NZ1 A;  4NZ3 A;  4Z2K A;  3FKE A;  2FN2 A;  2Y2J A;  1YU3 A;  4Z2J A;  1QO6 A;  2XD5 A;  2Y2O A;  1W1V A;  4IBI A;  1E6N A;  4IBB A;  3L26 A;  4GHA A;  2RTS A;  3L29 A;  1YU4 A;  3KS4 A;  4IBK A;  3M7P A;  2FFF B;  4IBG A;  1H0I A;  5BPV A;  4NY2 A;  2JE5 A;  1KS0 A;  1YUE A;  2Y2H A;  1W1P A;  2Y2Q A;  4OJ6 A;  1GOI A;  3N3F A;  1YU2 A;  4NYU A;  2Y2M A;  4Z2G A;  1E6R A;  2UWX A;  1EAK A;  4IBJ A;  1H8P A;  4IBF A;  3KS8 A;  2Y2N A;  4HMC A;  4GHL A;  2BG1 A;  1E15 A;  4HMD A;  4OJP A;  1W1T A;  1E88 A;  1OGG A;  4GH9 A;  3WD0 A;  4Z2I A;  2D49 A;  4IBC A;  4NZ5 A;  4MB3 A;  3WD2 A;  2JCH A;  1OGB A;  3WX7 A;  1J7M A;  2Y2P A;  2Y2L A;  3L27 A;  4Z2H A;  4QNL A;  3HSH A;  3MQL A;  1W1Y A;  4IBE A;  4NYY A;  1E8B A;  4OJ5 A;  4IBD A; 
#chains in the Genus database with same CATH homology
 1J7M A;  1CK7 A;  1EAK A;  3MQL A;  1L6J A;  2FN2 A;  2V5O A;  1GXD A;  1E8B A;  1PDC A;  3M7P A;  1E88 A;  1KS0 A;  1H8P A;  1CXW A;  1QO6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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