3C20A

Crystal structure of threonine-sensitive aspartokinase from methanococcus jannaschii with l-aspartate
Total Genus 154
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
154
sequence length
469
structure length
465
Chain Sequence
TTVMKFGGTSVGSGERIRHVAKIVTKRKKEDDDVVVVVSAMSEVTNALVEISQQALDVRDIAKVGDFIKFIREKHYKAIEEAIKSEEIKEEVKKIIDSRIEELEKVLIGVAYLGELTPKSRDYILSFGERLSSPILSGAIRDLGEKSIALEGGEAGIITDNNFGSARVKRLEVKERLLPLLKEGIIPVVTGFIGTTEEGYITTLGRGGSDYSAALIGYGLDADIIEIWTDVSGVYTTDPRLVPTARRIPKLSYIEAMELAYFGAKVLHPRTIEPAMEKGIPILVKNTFEPESEGTLITNDMEMSDSIVKAISTIKNVALINIFGAGMVGVSGTAARIFKALGEEEVNVILISQGSSETNISLVVSEEDVDKALKALKREFGDSFLNNNLIRDVSVDKDVCVISVVGAGMRGAKGIAGKIFTAVSESGANIKMIAQGSSEVNISFVIDEKDLLNCVRKLHEKFIEK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Structural Basis for Allosteric Inhibition of a Threonine-sensitive Aspartokinase.
pubmed doi rcsb
molecule tags Transferase
source organism Methanocaldococcus jannaschii
molecule keywords Probable aspartokinase
total genus 154
structure length 465
sequence length 469
chains with identical sequence B
ec nomenclature ec 2.7.2.4: Aspartate kinase.
pdb deposition date 2008-01-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00696 AA_kinase Amino acid kinase family
A PF01842 ACT ACT domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.2130.10 Alpha Beta 2-Layer Sandwich VC0802-like VC0802-like 3c20A02
3.40.1160.10 Alpha Beta 3-Layer(aba) Sandwich Carbamate kinase Acetylglutamate kinase-like 3c20A01
4KZTA 3WWNA 1ZVPA 3K56A 4NDOA 3S6GA 2HMFA 2V4YA 3EK5A 2E9YA 4NDQA 2BTYA 2RD5A 1YBDA 2J4JA 3K52A 4F6TA 3S6KA 3NWYA 4USJA 2BUFA 1E19A 1OHAA 2JI5A 2W21A 3QUOA 4NDPB 3K4YA 2R98A 3B8GA 2X2WA 2BNDA 2BRIA 2J4KA 3QVHA 3D40A 1OHBA 3L86A 2WE4A 3C1NA 1Z9DA 3D2MA 2J5VA 2J4LA 3AB2A 3WWMA 3S6HA 3K4OA 4I49A 2OGXA 2BNFA 4NDOB 3QVFA 2F06A 2V5HA 4AXSA 4JZ8A 4NDRA 2BMUA 4JZ9A 2R8VA 3C1MA 2BRXA 4A7XA 4F6TB 2VA1A 2J0XA 1OH9A 3ZZGA 2IJ9A 1B7BA 2BNEA 3ZZFA 3QURA 2WXBA 2JJXA 3L76A 2AP9A 2WE5A 3LL5A 3QUNA 3AB4A 3TVIA 4NDQB 3ZZIA 3LL9A 4AB7A 3D2PA 4Q1TA 2OGXB 1ZHVA 3D41A 3AAWA 4NDPA 4NDRB 2AKOA 4A7WA 3KZFA 2A1FA 4OLCA 3T7BA 2J5TA 2J0WA 3C20A 4JZ7A 3U6UA 2CDQA 3EK6A 3ZZHA 1GS5A 3LKKA 2JJ4A 1GSJA
chains in the Genus database with same CATH superfamily
3TM5A 4KZTA 3WWNA 1ZVPA 3K56A 4NDOA 3S6GA 2HMFA 2V4YA 3EK5A 2E9YA 4NDQA 2BTYA 2RD5A 1YBDA 2J4JA 3K52A 4F6TA 3S6KA 3NWYA 4USJA 2BUFA 3V97A 1E19A 1OHAA 2JI5A 2W21A 3QUOA 4NDPB 3K4YA 2R98A 3B8GA 2X2WA 2BNDA 2BRIA 2J4KA 3QVHA 3TM4A 3D40A 1OHBA 3L86A 2WE4A 3C1NA 1Z9DA 3D2MA 2J5VA 2J4LA 3AB2A 3WWMA 3S6HA 3K4OA 4I49A 3TLJA 2OGXA 3LDGA 2BNFA 4NDOB 3QVFA 2F06A 2V5HA 4AXSA 4JZ8A 4NDRA 2BMUA 4KR6A 4JZ9A 2R8VA 3C1MA 2BRXA 4A7XA 4F6TB 2VA1A 2J0XA 1OH9A 3ZZGA 2IJ9A 1B7BA 2BNEA 3ZZFA 3K0BA 3QURA 2WXBA 2JJXA 3LDUA 3L76A 2AP9A 2WE5A 3LL5A 3QUNA 3AB4A 3TVIA 4NDQB 3ZZIA 3LL9A 4AB7A 2C5SA 3D2PA 4Q1TA 2OGXB 1ZHVA 3D41A 3AAWA 4NDPA 4NDRB 2AKOA 4KR7A 4A7WA 3KZFA 2A1FA 4OLCA 3V8VA 4KR9A 3T7BA 2J5TA 2J0WA 3C20A 4JZ7A 3U6UA 2CDQA 3EK6A 3TMAA 3ZZHA 1GS5A 3LKKA 2JJ4A 1GSJA
chains in the Genus database with same CATH topology
3TM5A 4KZTA 3WWNA 1ZVPA 3K56A 4NDOA 3S6GA 2HMFA 2V4YA 3EK5A 2E9YA 4NDQA 2BTYA 2RD5A 1YBDA 2J4JA 3K52A 4F6TA 3S6KA 3NWYA 4USJA 2BUFA 3V97A 1E19A 1OHAA 2JI5A 2W21A 3QUOA 4NDPB 3K4YA 2R98A 3B8GA 2X2WA 2BNDA 2BRIA 2J4KA 3QVHA 3TM4A 3D40A 1OHBA 3L86A 2WE4A 3C1NA 1Z9DA 3D2MA 2J5VA 2J4LA 3AB2A 3WWMA 3S6HA 3K4OA 4I49A 3TLJA 2OGXA 3LDGA 2BNFA 4NDOB 3QVFA 2F06A 2V5HA 4AXSA 4JZ8A 4NDRA 2BMUA 4KR6A 4JZ9A 2R8VA 3C1MA 2BRXA 4A7XA 4F6TB 2VA1A 2J0XA 1OH9A 3ZZGA 2IJ9A 1B7BA 2BNEA 3ZZFA 3K0BA 3QURA 2WXBA 2JJXA 3LDUA 3L76A 2AP9A 2WE5A 3LL5A 3QUNA 3AB4A 3TVIA 4NDQB 3ZZIA 3LL9A 4AB7A 2C5SA 3D2PA 4Q1TA 2OGXB 1ZHVA 3D41A 3AAWA 4NDPA 4NDRB 2AKOA 4KR7A 4A7WA 3KZFA 2A1FA 4OLCA 3V8VA 4KR9A 3T7BA 2J5TA 2J0WA 3C20A 4JZ7A 3U6UA 2CDQA 3EK6A 3TMAA 3ZZHA 1GS5A 3LKKA 2JJ4A 1GSJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4KZT A;  3WWN A;  1ZVP A;  3K56 A;  4NDO A;  3S6G A;  2HMF A;  2V4Y A;  3EK5 A;  2E9Y A;  4NDQ A;  2BTY A;  2RD5 A;  1YBD A;  2J4J A;  3K52 A;  4F6T A;  3S6K A;  3NWY A;  4USJ A;  2BUF A;  1E19 A;  1OHA A;  2JI5 A;  2W21 A;  3QUO A;  4NDP B;  3K4Y A;  2R98 A;  3B8G A;  2X2W A;  2BND A;  2BRI A;  2J4K A;  3QVH A;  3D40 A;  1OHB A;  3L86 A;  2WE4 A;  3C1N A;  1Z9D A;  3D2M A;  2J5V A;  2J4L A;  3AB2 A;  3WWM A;  3S6H A;  3K4O A;  4I49 A;  2OGX A;  2BNF A;  4NDO B;  3QVF A;  2F06 A;  2V5H A;  4AXS A;  4JZ8 A;  4NDR A;  2BMU A;  4JZ9 A;  2R8V A;  3C1M A;  2BRX A;  4A7X A;  4F6T B;  2VA1 A;  2J0X A;  1OH9 A;  3ZZG A;  2IJ9 A;  1B7B A;  2BNE A;  3ZZF A;  3QUR A;  2WXB A;  2JJX A;  3L76 A;  2AP9 A;  2WE5 A;  3LL5 A;  3QUN A;  3AB4 A;  3TVI A;  4NDQ B;  3ZZI A;  3LL9 A;  4AB7 A;  3D2P A;  4Q1T A;  2OGX B;  1ZHV A;  3D41 A;  3AAW A;  4NDP A;  4NDR B;  2AKO A;  4A7W A;  3KZF A;  2A1F A;  4OLC A;  3T7B A;  2J5T A;  2J0W A;  3C20 A;  4JZ7 A;  3U6U A;  2CDQ A;  3EK6 A;  3ZZH A;  1GS5 A;  3LKK A;  2JJ4 A;  1GSJ A; 
#chains in the Genus database with same CATH topology
 3TM5 A;  4KZT A;  3WWN A;  1ZVP A;  3K56 A;  4NDO A;  3S6G A;  2HMF A;  2V4Y A;  3EK5 A;  2E9Y A;  4NDQ A;  2BTY A;  2RD5 A;  1YBD A;  2J4J A;  3K52 A;  4F6T A;  3S6K A;  3NWY A;  4USJ A;  2BUF A;  3V97 A;  1E19 A;  1OHA A;  2JI5 A;  2W21 A;  3QUO A;  4NDP B;  3K4Y A;  2R98 A;  3B8G A;  2X2W A;  2BND A;  2BRI A;  2J4K A;  3QVH A;  3TM4 A;  3D40 A;  1OHB A;  3L86 A;  2WE4 A;  3C1N A;  1Z9D A;  3D2M A;  2J5V A;  2J4L A;  3AB2 A;  3WWM A;  3S6H A;  3K4O A;  4I49 A;  3TLJ A;  2OGX A;  3LDG A;  2BNF A;  4NDO B;  3QVF A;  2F06 A;  2V5H A;  4AXS A;  4JZ8 A;  4NDR A;  2BMU A;  4KR6 A;  4JZ9 A;  2R8V A;  3C1M A;  2BRX A;  4A7X A;  4F6T B;  2VA1 A;  2J0X A;  1OH9 A;  3ZZG A;  2IJ9 A;  1B7B A;  2BNE A;  3ZZF A;  3K0B A;  3QUR A;  2WXB A;  2JJX A;  3LDU A;  3L76 A;  2AP9 A;  2WE5 A;  3LL5 A;  3QUN A;  3AB4 A;  3TVI A;  4NDQ B;  3ZZI A;  3LL9 A;  4AB7 A;  2C5S A;  3D2P A;  4Q1T A;  2OGX B;  1ZHV A;  3D41 A;  3AAW A;  4NDP A;  4NDR B;  2AKO A;  4KR7 A;  4A7W A;  3KZF A;  2A1F A;  4OLC A;  3V8V A;  4KR9 A;  3T7B A;  2J5T A;  2J0W A;  3C20 A;  4JZ7 A;  3U6U A;  2CDQ A;  3EK6 A;  3TMA A;  3ZZH A;  1GS5 A;  3LKK A;  2JJ4 A;  1GSJ A; 
#chains in the Genus database with same CATH homology
 3TM5 A;  4KZT A;  3WWN A;  1ZVP A;  3K56 A;  4NDO A;  3S6G A;  2HMF A;  2V4Y A;  3EK5 A;  2E9Y A;  4NDQ A;  2BTY A;  2RD5 A;  1YBD A;  2J4J A;  3K52 A;  4F6T A;  3S6K A;  3NWY A;  4USJ A;  2BUF A;  3V97 A;  1E19 A;  1OHA A;  2JI5 A;  2W21 A;  3QUO A;  4NDP B;  3K4Y A;  2R98 A;  3B8G A;  2X2W A;  2BND A;  2BRI A;  2J4K A;  3QVH A;  3TM4 A;  3D40 A;  1OHB A;  3L86 A;  2WE4 A;  3C1N A;  1Z9D A;  3D2M A;  2J5V A;  2J4L A;  3AB2 A;  3WWM A;  3S6H A;  3K4O A;  4I49 A;  3TLJ A;  2OGX A;  3LDG A;  2BNF A;  4NDO B;  3QVF A;  2F06 A;  2V5H A;  4AXS A;  4JZ8 A;  4NDR A;  2BMU A;  4KR6 A;  4JZ9 A;  2R8V A;  3C1M A;  2BRX A;  4A7X A;  4F6T B;  2VA1 A;  2J0X A;  1OH9 A;  3ZZG A;  2IJ9 A;  1B7B A;  2BNE A;  3ZZF A;  3K0B A;  3QUR A;  2WXB A;  2JJX A;  3LDU A;  3L76 A;  2AP9 A;  2WE5 A;  3LL5 A;  3QUN A;  3AB4 A;  3TVI A;  4NDQ B;  3ZZI A;  3LL9 A;  4AB7 A;  2C5S A;  3D2P A;  4Q1T A;  2OGX B;  1ZHV A;  3D41 A;  3AAW A;  4NDP A;  4NDR B;  2AKO A;  4KR7 A;  4A7W A;  3KZF A;  2A1F A;  4OLC A;  3V8V A;  4KR9 A;  3T7B A;  2J5T A;  2J0W A;  3C20 A;  4JZ7 A;  3U6U A;  2CDQ A;  3EK6 A;  3TMA A;  3ZZH A;  1GS5 A;  3LKK A;  2JJ4 A;  1GSJ A; 
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