1JMQA

Yap65 (l30k mutant) ww domain in complex with gtppppytvg peptide
Total Genus 2
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
2
sequence length
46
structure length
46
Chain Sequence
FEIPDDVPLPAGWEMAKTSSGQRYFKNHIDQTTTWQDPRKAMLSQM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structures of the YAP65 WW domain and the variant L30 K in complex with the peptides GTPPPPYTVG, N-(n-octyl)-GPPPY and PLPPY and the application of peptide libraries reveal a minimal binding epitope.
pubmed doi rcsb
molecule tags Structural protein
source organism Homo sapiens
molecule keywords 65 KDA YES-ASSOCIATED PROTEIN
total genus 2
structure length 46
sequence length 46
ec nomenclature
pdb deposition date 2001-07-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00397 WW WW domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.70.10 Mainly Beta Single Sheet Ubiquitin Ligase Nedd4; Chain: W; Ubiquitin Ligase Nedd4; Chain: W; 1jmqA00
3KAFA 4U85A 2F21A 2ZQUA 2JV4A 2DMVA 2RE3A 2LAJA 1TK7A 2XP7A 2XP9A 2XP8A 3WH0A 1I5HW 2YSGA 2XP3A 3ODKA 2EZ5W 1K9QA 2JMFA 2ZQTA 2M3OW 1O6WA 3CNGA 2ZR5A 2YSBA 2YSIA 2DWVA 2ZR4A 3KABA 2MDIA 3M85A 1ZCNA 2XPBA 3M7NA 2M8JA 2ZQVA 2BA1A 2XP5A 1NMVA 4U84A 3KAIA 3KCEA 1F8AB 2L4JA 2JX8A 2DJYA 2XPAA 3TCZA 5AHTA 1EG3A 4U86A 3LE4A 3NTPA 1JMQA 2ZR6A 4E5RA 2M8IA 3OOBA 2KXQA 1WMVA 2DK1A 1YW5A 2JXWA 2ITKA 5CQ2A 2XP6A 3TDBA 3TC5A 3KADA 2E45A 3KAGA 3KAHA 1K9RA 3L4HA 2YSHA 4REXA 2YSFA 2ZAJA 1WR7A 2DK7A 2XP4A 1EG4A 4QIBA 2Q5AA 1PINA 2ZQSA
chains in the Genus database with same CATH superfamily
3KAFA 5E65A 4U85A 1RP5A 2F21A 3FSBA 4A0TA 3MCBA 2ZQUA 2JV4A 2DMVA 2RE3A 2LAJA 1TK7A 2XP7A 2XP9A 2XP8A 3WH0A 1I5HW 3MQHA 2YSGA 2WAEA 2XP3A 3ODKA 2EZ5W 4GLXA 1K9QA 2JMFA 3LKXA 2ZQTA 2M3OW 1O6WA 3CNGA 5E62A 2ZR5A 2YSBA 2YSIA 2DWVA 2ZR4A 2WADA 3KABA 2MDIA 5U47A 3M85A 1ZCNA 2XPBA 3LKXB 3M7NA 2M8JA 2ZQVA 2BA1A 2XP5A 1NMVA 4U84A 3KAIA 3KCEA 1F8AB 2QRVA 3FS8A 2L4JA 4A0UA 2JX8A 5E5WA 2DJYA 2XPAA 3TCZA 5AHTA 1EG3A 4U86A 3LE4A 1FLCA 3NTPA 1JMQA 1TR8A 3PQHA 2ZR6A 2OWOA 4E5RA 2M8IA 2Y8NB 3OOBA 5E66A 2KXQA 1WMVA 2DK1A 1YW5A 2JXWA 2ITKA 5CQ2A 5E64A 2XP6A 3TDBA 3MQGA 3TC5A 3KADA 2E45A 3KAGA 3KAHA 1K9RA 3FSCA 3L4HA 2YAJB 2YSHA 4REXA 2YSFA 2ZAJA 1WR7A 3MCBB 2DK7A 2XP4A 1EG4A 4QIBA 2Q5AA 1PINA 2ZQSA
chains in the Genus database with same CATH topology
3KAFA 5E65A 4U85A 1RP5A 2F21A 3FSBA 4A0TA 3MCBA 2ZQUA 2JV4A 2DMVA 2RE3A 2LAJA 1TK7A 2XP7A 2XP9A 2XP8A 3WH0A 1I5HW 3MQHA 2YSGA 2WAEA 2XP3A 3ODKA 2EZ5W 4GLXA 1K9QA 2JMFA 3LKXA 2ZQTA 2M3OW 1O6WA 3CNGA 5E62A 2ZR5A 2YSBA 2YSIA 2DWVA 2ZR4A 2WADA 3KABA 2MDIA 5U47A 3M85A 1ZCNA 2XPBA 3LKXB 3M7NA 2M8JA 2ZQVA 2BA1A 2XP5A 1NMVA 4U84A 3KAIA 3KCEA 1F8AB 2QRVA 3FS8A 2L4JA 4A0UA 2JX8A 5E5WA 2DJYA 2XPAA 3TCZA 5AHTA 1EG3A 4U86A 3LE4A 1FLCA 3NTPA 1JMQA 1TR8A 3PQHA 2ZR6A 2OWOA 4E5RA 2M8IA 2Y8NB 3OOBA 5E66A 2KXQA 1WMVA 2DK1A 1YW5A 2JXWA 2ITKA 5CQ2A 5E64A 2XP6A 3TDBA 3MQGA 3TC5A 3KADA 2E45A 3KAGA 3KAHA 1K9RA 3FSCA 3L4HA 2YAJB 2YSHA 4REXA 2YSFA 2ZAJA 1WR7A 3MCBB 2DK7A 2XP4A 1EG4A 4QIBA 2Q5AA 1PINA 2ZQSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3KAF A;  4U85 A;  2F21 A;  2ZQU A;  2JV4 A;  2DMV A;  2RE3 A;  2LAJ A;  1TK7 A;  2XP7 A;  2XP9 A;  2XP8 A;  3WH0 A;  1I5H W;  2YSG A;  2XP3 A;  3ODK A;  2EZ5 W;  1K9Q A;  2JMF A;  2ZQT A;  2M3O W;  1O6W A;  3CNG A;  2ZR5 A;  2YSB A;  2YSI A;  2DWV A;  2ZR4 A;  3KAB A;  2MDI A;  3M85 A;  1ZCN A;  2XPB A;  3M7N A;  2M8J A;  2ZQV A;  2BA1 A;  2XP5 A;  1NMV A;  4U84 A;  3KAI A;  3KCE A;  1F8A B;  2L4J A;  2JX8 A;  2DJY A;  2XPA A;  3TCZ A;  5AHT A;  1EG3 A;  4U86 A;  3LE4 A;  3NTP A;  1JMQ A;  2ZR6 A;  4E5R A;  2M8I A;  3OOB A;  2KXQ A;  1WMV A;  2DK1 A;  1YW5 A;  2JXW A;  2ITK A;  5CQ2 A;  2XP6 A;  3TDB A;  3TC5 A;  3KAD A;  2E45 A;  3KAG A;  3KAH A;  1K9R A;  3L4H A;  2YSH A;  4REX A;  2YSF A;  2ZAJ A;  1WR7 A;  2DK7 A;  2XP4 A;  1EG4 A;  4QIB A;  2Q5A A;  1PIN A;  2ZQS A; 
#chains in the Genus database with same CATH topology
 3KAF A;  5E65 A;  4U85 A;  1RP5 A;  2F21 A;  3FSB A;  4A0T A;  3MCB A;  2ZQU A;  2JV4 A;  2DMV A;  2RE3 A;  2LAJ A;  1TK7 A;  2XP7 A;  2XP9 A;  2XP8 A;  3WH0 A;  1I5H W;  3MQH A;  2YSG A;  2WAE A;  2XP3 A;  3ODK A;  2EZ5 W;  4GLX A;  1K9Q A;  2JMF A;  3LKX A;  2ZQT A;  2M3O W;  1O6W A;  3CNG A;  5E62 A;  2ZR5 A;  2YSB A;  2YSI A;  2DWV A;  2ZR4 A;  2WAD A;  3KAB A;  2MDI A;  5U47 A;  3M85 A;  1ZCN A;  2XPB A;  3LKX B;  3M7N A;  2M8J A;  2ZQV A;  2BA1 A;  2XP5 A;  1NMV A;  4U84 A;  3KAI A;  3KCE A;  1F8A B;  2QRV A;  3FS8 A;  2L4J A;  4A0U A;  2JX8 A;  5E5W A;  2DJY A;  2XPA A;  3TCZ A;  5AHT A;  1EG3 A;  4U86 A;  3LE4 A;  1FLC A;  3NTP A;  1JMQ A;  1TR8 A;  3PQH A;  2ZR6 A;  2OWO A;  4E5R A;  2M8I A;  2Y8N B;  3OOB A;  5E66 A;  2KXQ A;  1WMV A;  2DK1 A;  1YW5 A;  2JXW A;  2ITK A;  5CQ2 A;  5E64 A;  2XP6 A;  3TDB A;  3MQG A;  3TC5 A;  3KAD A;  2E45 A;  3KAG A;  3KAH A;  1K9R A;  3FSC A;  3L4H A;  2YAJ B;  2YSH A;  4REX A;  2YSF A;  2ZAJ A;  1WR7 A;  3MCB B;  2DK7 A;  2XP4 A;  1EG4 A;  4QIB A;  2Q5A A;  1PIN A;  2ZQS A; 
#chains in the Genus database with same CATH homology
 3KAF A;  5E65 A;  4U85 A;  1RP5 A;  2F21 A;  3FSB A;  4A0T A;  3MCB A;  2ZQU A;  2JV4 A;  2DMV A;  2RE3 A;  2LAJ A;  1TK7 A;  2XP7 A;  2XP9 A;  2XP8 A;  3WH0 A;  1I5H W;  3MQH A;  2YSG A;  2WAE A;  2XP3 A;  3ODK A;  2EZ5 W;  4GLX A;  1K9Q A;  2JMF A;  3LKX A;  2ZQT A;  2M3O W;  1O6W A;  3CNG A;  5E62 A;  2ZR5 A;  2YSB A;  2YSI A;  2DWV A;  2ZR4 A;  2WAD A;  3KAB A;  2MDI A;  5U47 A;  3M85 A;  1ZCN A;  2XPB A;  3LKX B;  3M7N A;  2M8J A;  2ZQV A;  2BA1 A;  2XP5 A;  1NMV A;  4U84 A;  3KAI A;  3KCE A;  1F8A B;  2QRV A;  3FS8 A;  2L4J A;  4A0U A;  2JX8 A;  5E5W A;  2DJY A;  2XPA A;  3TCZ A;  5AHT A;  1EG3 A;  4U86 A;  3LE4 A;  1FLC A;  3NTP A;  1JMQ A;  1TR8 A;  3PQH A;  2ZR6 A;  2OWO A;  4E5R A;  2M8I A;  2Y8N B;  3OOB A;  5E66 A;  2KXQ A;  1WMV A;  2DK1 A;  1YW5 A;  2JXW A;  2ITK A;  5CQ2 A;  5E64 A;  2XP6 A;  3TDB A;  3MQG A;  3TC5 A;  3KAD A;  2E45 A;  3KAG A;  3KAH A;  1K9R A;  3FSC A;  3L4H A;  2YAJ B;  2YSH A;  4REX A;  2YSF A;  2ZAJ A;  1WR7 A;  3MCB B;  2DK7 A;  2XP4 A;  1EG4 A;  4QIB A;  2Q5A A;  1PIN A;  2ZQS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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