5AHTA

Third ww domain from the e3 ubiquitin-protein ligase nedd4
Total Genus 9
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
9
sequence length
43
structure length
43
Chain Sequence
GSMEQGFLPKGWEVRHAPNGRPFFIDHNTKTTTWEDPRLKIPA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Nedd4-1 Ww Domain Recognizes the Py Motif Peptide Through Coupled Folding and Binding Equilibria.
pubmed doi rcsb
molecule tags Isomerase
source organism Homo sapiens
molecule keywords E3 UBIQUITIN-PROTEIN LIGASE NEDD4
total genus 9
structure length 43
sequence length 43
ec nomenclature ec 2.3.2.26: HECT-type E3 ubiquitin transferase.
pdb deposition date 2015-02-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00397 WW WW domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.70.10 Mainly Beta Single Sheet Ubiquitin Ligase Nedd4; Chain: W; Ubiquitin Ligase Nedd4; Chain: W; 5ahtA01
1NMVA 2M8IA 3KCEA 2YSHA 1EG3A 2Q5AA 2DWVA 2ITKA 3KAFA 2F21A 5CQ2A 2E45A 2JMFA 1K9RA 3LE4A 2ZR5A 1JMQA 3KAHA 1WMVA 3KAIA 2ZR6A 3M7NA 4U86A 2DMVA 2DJYA 3KAGA 1WR7A 1F8AB 2XPAA 2YSIA 3TCZA 2M3OW 2LAJA 2YSBA 3KADA 2DK7A 2KXQA 4U84A 2ZAJA 2XP8A 2ZQUA 1ZCNA 1EG4A 1O6WA 2JXWA 3ODKA 4U85A 2MDIA 4QIBA 2ZQTA 2XP5A 2YSFA 2YSGA 1YW5A 3KABA 2EZ5W 3TC5A 3NTPA 3L4HA 4REXA 3OOBA 2ZQSA 2RE3A 3TDBA 2XP7A 2L4JA 2XP4A 1PINA 3M85A 1K9QA 4E5RA 2XP3A 3WH0A 1TK7A 2DK1A 2ZQVA 2XPBA 2M8JA 2XP9A 5AHTA 2BA1A 2JX8A 2ZR4A 2XP6A 1I5HW 3CNGA 2JV4A
chains in the Genus database with same CATH superfamily
3MQGA 3LKXB 5U47A 4A0UA 1NMVA 2M8IA 3FSBA 4GLXA 3KCEA 2YSHA 1EG3A 2Q5AA 2DWVA 2ITKA 5E65A 3KAFA 2F21A 5CQ2A 2E45A 2JMFA 2Y8NB 1K9RA 3LE4A 2ZR5A 3MQHA 1JMQA 3KAHA 1WMVA 3KAIA 2ZR6A 3M7NA 4U86A 2DMVA 2DJYA 2WADA 3KAGA 2YAJB 1WR7A 1F8AB 2XPAA 2YSIA 3TCZA 2OWOA 2M3OW 2LAJA 2YSBA 3KADA 2DK7A 2KXQA 4U84A 2ZAJA 1RP5A 2XP8A 1TR8A 2ZQUA 1ZCNA 1EG4A 1O6WA 2JXWA 3MCBB 3ODKA 3MCBA 3PQHA 4U85A 5E5WA 2MDIA 4QIBA 3FSCA 2ZQTA 2XP5A 4A0TA 1FLCA 2YSFA 2YSGA 1YW5A 3KABA 2QRVA 2EZ5W 3TC5A 3NTPA 3L4HA 4REXA 3OOBA 2ZQSA 2RE3A 3LKXA 5E64A 3TDBA 2XP7A 2L4JA 2XP4A 1PINA 3M85A 1K9QA 5E62A 4E5RA 2XP3A 3WH0A 1TK7A 3FS8A 2DK1A 2ZQVA 2XPBA 2M8JA 2WAEA 2XP9A 5AHTA 2BA1A 2JX8A 2ZR4A 2XP6A 1I5HW 3CNGA 5E66A 2JV4A
chains in the Genus database with same CATH topology
3MQGA 3LKXB 5U47A 4A0UA 1NMVA 2M8IA 3FSBA 4GLXA 3KCEA 2YSHA 1EG3A 2Q5AA 2DWVA 2ITKA 5E65A 3KAFA 2F21A 5CQ2A 2E45A 2JMFA 2Y8NB 1K9RA 3LE4A 2ZR5A 3MQHA 1JMQA 3KAHA 1WMVA 3KAIA 2ZR6A 3M7NA 4U86A 2DMVA 2DJYA 2WADA 3KAGA 2YAJB 1WR7A 1F8AB 2XPAA 2YSIA 3TCZA 2OWOA 2M3OW 2LAJA 2YSBA 3KADA 2DK7A 2KXQA 4U84A 2ZAJA 1RP5A 2XP8A 1TR8A 2ZQUA 1ZCNA 1EG4A 1O6WA 2JXWA 3MCBB 3ODKA 3MCBA 3PQHA 4U85A 5E5WA 2MDIA 4QIBA 3FSCA 2ZQTA 2XP5A 4A0TA 1FLCA 2YSFA 2YSGA 1YW5A 3KABA 2QRVA 2EZ5W 3TC5A 3NTPA 3L4HA 4REXA 3OOBA 2ZQSA 2RE3A 3LKXA 5E64A 3TDBA 2XP7A 2L4JA 2XP4A 1PINA 3M85A 1K9QA 5E62A 4E5RA 2XP3A 3WH0A 1TK7A 3FS8A 2DK1A 2ZQVA 2XPBA 2M8JA 2WAEA 2XP9A 5AHTA 2BA1A 2JX8A 2ZR4A 2XP6A 1I5HW 3CNGA 5E66A 2JV4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1NMV A;  2M8I A;  3KCE A;  2YSH A;  1EG3 A;  2Q5A A;  2DWV A;  2ITK A;  3KAF A;  2F21 A;  5CQ2 A;  2E45 A;  2JMF A;  1K9R A;  3LE4 A;  2ZR5 A;  1JMQ A;  3KAH A;  1WMV A;  3KAI A;  2ZR6 A;  3M7N A;  4U86 A;  2DMV A;  2DJY A;  3KAG A;  1WR7 A;  1F8A B;  2XPA A;  2YSI A;  3TCZ A;  2M3O W;  2LAJ A;  2YSB A;  3KAD A;  2DK7 A;  2KXQ A;  4U84 A;  2ZAJ A;  2XP8 A;  2ZQU A;  1ZCN A;  1EG4 A;  1O6W A;  2JXW A;  3ODK A;  4U85 A;  2MDI A;  4QIB A;  2ZQT A;  2XP5 A;  2YSF A;  2YSG A;  1YW5 A;  3KAB A;  2EZ5 W;  3TC5 A;  3NTP A;  3L4H A;  4REX A;  3OOB A;  2ZQS A;  2RE3 A;  3TDB A;  2XP7 A;  2L4J A;  2XP4 A;  1PIN A;  3M85 A;  1K9Q A;  4E5R A;  2XP3 A;  3WH0 A;  1TK7 A;  2DK1 A;  2ZQV A;  2XPB A;  2M8J A;  2XP9 A;  5AHT A;  2BA1 A;  2JX8 A;  2ZR4 A;  2XP6 A;  1I5H W;  3CNG A;  2JV4 A; 
#chains in the Genus database with same CATH topology
 3MQG A;  3LKX B;  5U47 A;  4A0U A;  1NMV A;  2M8I A;  3FSB A;  4GLX A;  3KCE A;  2YSH A;  1EG3 A;  2Q5A A;  2DWV A;  2ITK A;  5E65 A;  3KAF A;  2F21 A;  5CQ2 A;  2E45 A;  2JMF A;  2Y8N B;  1K9R A;  3LE4 A;  2ZR5 A;  3MQH A;  1JMQ A;  3KAH A;  1WMV A;  3KAI A;  2ZR6 A;  3M7N A;  4U86 A;  2DMV A;  2DJY A;  2WAD A;  3KAG A;  2YAJ B;  1WR7 A;  1F8A B;  2XPA A;  2YSI A;  3TCZ A;  2OWO A;  2M3O W;  2LAJ A;  2YSB A;  3KAD A;  2DK7 A;  2KXQ A;  4U84 A;  2ZAJ A;  1RP5 A;  2XP8 A;  1TR8 A;  2ZQU A;  1ZCN A;  1EG4 A;  1O6W A;  2JXW A;  3MCB B;  3ODK A;  3MCB A;  3PQH A;  4U85 A;  5E5W A;  2MDI A;  4QIB A;  3FSC A;  2ZQT A;  2XP5 A;  4A0T A;  1FLC A;  2YSF A;  2YSG A;  1YW5 A;  3KAB A;  2QRV A;  2EZ5 W;  3TC5 A;  3NTP A;  3L4H A;  4REX A;  3OOB A;  2ZQS A;  2RE3 A;  3LKX A;  5E64 A;  3TDB A;  2XP7 A;  2L4J A;  2XP4 A;  1PIN A;  3M85 A;  1K9Q A;  5E62 A;  4E5R A;  2XP3 A;  3WH0 A;  1TK7 A;  3FS8 A;  2DK1 A;  2ZQV A;  2XPB A;  2M8J A;  2WAE A;  2XP9 A;  5AHT A;  2BA1 A;  2JX8 A;  2ZR4 A;  2XP6 A;  1I5H W;  3CNG A;  5E66 A;  2JV4 A; 
#chains in the Genus database with same CATH homology
 3MQG A;  3LKX B;  5U47 A;  4A0U A;  1NMV A;  2M8I A;  3FSB A;  4GLX A;  3KCE A;  2YSH A;  1EG3 A;  2Q5A A;  2DWV A;  2ITK A;  5E65 A;  3KAF A;  2F21 A;  5CQ2 A;  2E45 A;  2JMF A;  2Y8N B;  1K9R A;  3LE4 A;  2ZR5 A;  3MQH A;  1JMQ A;  3KAH A;  1WMV A;  3KAI A;  2ZR6 A;  3M7N A;  4U86 A;  2DMV A;  2DJY A;  2WAD A;  3KAG A;  2YAJ B;  1WR7 A;  1F8A B;  2XPA A;  2YSI A;  3TCZ A;  2OWO A;  2M3O W;  2LAJ A;  2YSB A;  3KAD A;  2DK7 A;  2KXQ A;  4U84 A;  2ZAJ A;  1RP5 A;  2XP8 A;  1TR8 A;  2ZQU A;  1ZCN A;  1EG4 A;  1O6W A;  2JXW A;  3MCB B;  3ODK A;  3MCB A;  3PQH A;  4U85 A;  5E5W A;  2MDI A;  4QIB A;  3FSC A;  2ZQT A;  2XP5 A;  4A0T A;  1FLC A;  2YSF A;  2YSG A;  1YW5 A;  3KAB A;  2QRV A;  2EZ5 W;  3TC5 A;  3NTP A;  3L4H A;  4REX A;  3OOB A;  2ZQS A;  2RE3 A;  3LKX A;  5E64 A;  3TDB A;  2XP7 A;  2L4J A;  2XP4 A;  1PIN A;  3M85 A;  1K9Q A;  5E62 A;  4E5R A;  2XP3 A;  3WH0 A;  1TK7 A;  3FS8 A;  2DK1 A;  2ZQV A;  2XPB A;  2M8J A;  2WAE A;  2XP9 A;  5AHT A;  2BA1 A;  2JX8 A;  2ZR4 A;  2XP6 A;  1I5H W;  3CNG A;  5E66 A;  2JV4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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