2M8JA

Structure of pin1 ww domain phospho-mimic s16e
Total Genus 3
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
3
sequence length
43
structure length
43
Chain Sequence
GLEHMADEEKLPPGWEKRMERSSGRVYYFNHITNASQWERPSG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Isomerase
molecule keywords Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
publication title Molecular crowding drives active Pin1 into nonspecific complexes with endogenous proteins prior to substrate recognition.
pubmed doi rcsb
source organism Homo sapiens
total genus 3
structure length 43
sequence length 43
ec nomenclature ec 5.2.1.8: Peptidylprolyl isomerase.
pdb deposition date 2013-05-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00397 WW WW domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.70.10 Mainly Beta Single Sheet Ubiquitin Ligase Nedd4; Chain: W; Ubiquitin Ligase Nedd4; Chain: W; 2m8jA01
2JMFA 2DJYA 3TC5A 2Q5AA 1JMQA 2M3OW 2ZR5A 3KADA 2ITKA 4U85A 2JX8A 2XPBA 3TCZA 3L4HA 2XP5A 4REXA 2XP4A 4U84A 2ZQSA 2KXQA 2ZQUA 2M8IA 2DK1A 2M8JA 1ZCNA 1TK7A 2ZAJA 2YSFA 1NMVA 3KAHA 2YSGA 1K9QA 2ZR6A 1YW5A 3M7NA 2XP3A 2RE3A 2XP8A 2DMVA 1WR7A 4QIBA 3WH0A 1K9RA 5CQ2A 3ODKA 3KAGA 3M85A 1O6WA 2YSHA 2LAJA 3CNGA 2EZ5W 2XPAA 3KCEA 3NTPA 2F21A 2L4JA 2ZQVA 2JV4A 1F8AB 2XP9A 4E5RA 2BA1A 3TDBA 3KAFA 2DWVA 1WMVA 2ZR4A 3KAIA 5AHTA 2MDIA 1PINA 2E45A 4U86A 2ZQTA 2XP6A 3KABA 1EG3A 2XP7A 3OOBA 3LE4A 1EG4A 2YSIA 2YSBA 1I5HW 2JXWA 2DK7A
chains in the Genus database with same CATH superfamily
2JMFA 2DJYA 3TC5A 2Q5AA 1JMQA 2WAEA 2M3OW 2ZR5A 3KADA 2ITKA 4U85A 2JX8A 2XPBA 3TCZA 3L4HA 2XP5A 4REXA 2XP4A 3MCBA 4U84A 1TR8A 2ZQSA 4A0TA 2OWOA 3MCBB 5E62A 2KXQA 4A0UA 2ZQUA 2M8IA 2DK1A 2M8JA 5E5WA 5U47A 1ZCNA 1TK7A 2ZAJA 2YSFA 1NMVA 3KAHA 5E65A 2YSGA 1K9QA 2ZR6A 3FSCA 3LKXA 1YW5A 3M7NA 3LKXB 2XP3A 2RE3A 2XP8A 2DMVA 1WR7A 4QIBA 3WH0A 1K9RA 5CQ2A 2YAJB 3ODKA 3KAGA 3M85A 1O6WA 2YSHA 2Y8NB 2LAJA 3CNGA 2EZ5W 3MQGA 2XPAA 3KCEA 3PQHA 3NTPA 1FLCA 2F21A 2L4JA 2ZQVA 2JV4A 1F8AB 2XP9A 4E5RA 2BA1A 3TDBA 3KAFA 2DWVA 1WMVA 5E66A 2ZR4A 3KAIA 5AHTA 3FSBA 2MDIA 1PINA 3FS8A 2E45A 3MQHA 4U86A 2ZQTA 2XP6A 2WADA 3KABA 1EG3A 2XP7A 3OOBA 4GLXA 2QRVA 3LE4A 1EG4A 5E64A 2YSIA 2YSBA 1I5HW 2JXWA 1RP5A 2DK7A
chains in the Genus database with same CATH topology
2JMFA 2DJYA 3TC5A 2Q5AA 1JMQA 2WAEA 2M3OW 2ZR5A 3KADA 2ITKA 4U85A 2JX8A 2XPBA 3TCZA 3L4HA 2XP5A 4REXA 2XP4A 3MCBA 4U84A 1TR8A 2ZQSA 4A0TA 2OWOA 3MCBB 5E62A 2KXQA 4A0UA 2ZQUA 2M8IA 2DK1A 2M8JA 5E5WA 5U47A 1ZCNA 1TK7A 2ZAJA 2YSFA 1NMVA 3KAHA 5E65A 2YSGA 1K9QA 2ZR6A 3FSCA 3LKXA 1YW5A 3M7NA 3LKXB 2XP3A 2RE3A 2XP8A 2DMVA 1WR7A 4QIBA 3WH0A 1K9RA 5CQ2A 2YAJB 3ODKA 3KAGA 3M85A 1O6WA 2YSHA 2Y8NB 2LAJA 3CNGA 2EZ5W 3MQGA 2XPAA 3KCEA 3PQHA 3NTPA 1FLCA 2F21A 2L4JA 2ZQVA 2JV4A 1F8AB 2XP9A 4E5RA 2BA1A 3TDBA 3KAFA 2DWVA 1WMVA 5E66A 2ZR4A 3KAIA 5AHTA 3FSBA 2MDIA 1PINA 3FS8A 2E45A 3MQHA 4U86A 2ZQTA 2XP6A 2WADA 3KABA 1EG3A 2XP7A 3OOBA 4GLXA 2QRVA 3LE4A 1EG4A 5E64A 2YSIA 2YSBA 1I5HW 2JXWA 1RP5A 2DK7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2JMF A;  2DJY A;  3TC5 A;  2Q5A A;  1JMQ A;  2M3O W;  2ZR5 A;  3KAD A;  2ITK A;  4U85 A;  2JX8 A;  2XPB A;  3TCZ A;  3L4H A;  2XP5 A;  4REX A;  2XP4 A;  4U84 A;  2ZQS A;  2KXQ A;  2ZQU A;  2M8I A;  2DK1 A;  2M8J A;  1ZCN A;  1TK7 A;  2ZAJ A;  2YSF A;  1NMV A;  3KAH A;  2YSG A;  1K9Q A;  2ZR6 A;  1YW5 A;  3M7N A;  2XP3 A;  2RE3 A;  2XP8 A;  2DMV A;  1WR7 A;  4QIB A;  3WH0 A;  1K9R A;  5CQ2 A;  3ODK A;  3KAG A;  3M85 A;  1O6W A;  2YSH A;  2LAJ A;  3CNG A;  2EZ5 W;  2XPA A;  3KCE A;  3NTP A;  2F21 A;  2L4J A;  2ZQV A;  2JV4 A;  1F8A B;  2XP9 A;  4E5R A;  2BA1 A;  3TDB A;  3KAF A;  2DWV A;  1WMV A;  2ZR4 A;  3KAI A;  5AHT A;  2MDI A;  1PIN A;  2E45 A;  4U86 A;  2ZQT A;  2XP6 A;  3KAB A;  1EG3 A;  2XP7 A;  3OOB A;  3LE4 A;  1EG4 A;  2YSI A;  2YSB A;  1I5H W;  2JXW A;  2DK7 A; 
#chains in the Genus database with same CATH topology
 2JMF A;  2DJY A;  3TC5 A;  2Q5A A;  1JMQ A;  2WAE A;  2M3O W;  2ZR5 A;  3KAD A;  2ITK A;  4U85 A;  2JX8 A;  2XPB A;  3TCZ A;  3L4H A;  2XP5 A;  4REX A;  2XP4 A;  3MCB A;  4U84 A;  1TR8 A;  2ZQS A;  4A0T A;  2OWO A;  3MCB B;  5E62 A;  2KXQ A;  4A0U A;  2ZQU A;  2M8I A;  2DK1 A;  2M8J A;  5E5W A;  5U47 A;  1ZCN A;  1TK7 A;  2ZAJ A;  2YSF A;  1NMV A;  3KAH A;  5E65 A;  2YSG A;  1K9Q A;  2ZR6 A;  3FSC A;  3LKX A;  1YW5 A;  3M7N A;  3LKX B;  2XP3 A;  2RE3 A;  2XP8 A;  2DMV A;  1WR7 A;  4QIB A;  3WH0 A;  1K9R A;  5CQ2 A;  2YAJ B;  3ODK A;  3KAG A;  3M85 A;  1O6W A;  2YSH A;  2Y8N B;  2LAJ A;  3CNG A;  2EZ5 W;  3MQG A;  2XPA A;  3KCE A;  3PQH A;  3NTP A;  1FLC A;  2F21 A;  2L4J A;  2ZQV A;  2JV4 A;  1F8A B;  2XP9 A;  4E5R A;  2BA1 A;  3TDB A;  3KAF A;  2DWV A;  1WMV A;  5E66 A;  2ZR4 A;  3KAI A;  5AHT A;  3FSB A;  2MDI A;  1PIN A;  3FS8 A;  2E45 A;  3MQH A;  4U86 A;  2ZQT A;  2XP6 A;  2WAD A;  3KAB A;  1EG3 A;  2XP7 A;  3OOB A;  4GLX A;  2QRV A;  3LE4 A;  1EG4 A;  5E64 A;  2YSI A;  2YSB A;  1I5H W;  2JXW A;  1RP5 A;  2DK7 A; 
#chains in the Genus database with same CATH homology
 2JMF A;  2DJY A;  3TC5 A;  2Q5A A;  1JMQ A;  2WAE A;  2M3O W;  2ZR5 A;  3KAD A;  2ITK A;  4U85 A;  2JX8 A;  2XPB A;  3TCZ A;  3L4H A;  2XP5 A;  4REX A;  2XP4 A;  3MCB A;  4U84 A;  1TR8 A;  2ZQS A;  4A0T A;  2OWO A;  3MCB B;  5E62 A;  2KXQ A;  4A0U A;  2ZQU A;  2M8I A;  2DK1 A;  2M8J A;  5E5W A;  5U47 A;  1ZCN A;  1TK7 A;  2ZAJ A;  2YSF A;  1NMV A;  3KAH A;  5E65 A;  2YSG A;  1K9Q A;  2ZR6 A;  3FSC A;  3LKX A;  1YW5 A;  3M7N A;  3LKX B;  2XP3 A;  2RE3 A;  2XP8 A;  2DMV A;  1WR7 A;  4QIB A;  3WH0 A;  1K9R A;  5CQ2 A;  2YAJ B;  3ODK A;  3KAG A;  3M85 A;  1O6W A;  2YSH A;  2Y8N B;  2LAJ A;  3CNG A;  2EZ5 W;  3MQG A;  2XPA A;  3KCE A;  3PQH A;  3NTP A;  1FLC A;  2F21 A;  2L4J A;  2ZQV A;  2JV4 A;  1F8A B;  2XP9 A;  4E5R A;  2BA1 A;  3TDB A;  3KAF A;  2DWV A;  1WMV A;  5E66 A;  2ZR4 A;  3KAI A;  5AHT A;  3FSB A;  2MDI A;  1PIN A;  3FS8 A;  2E45 A;  3MQH A;  4U86 A;  2ZQT A;  2XP6 A;  2WAD A;  3KAB A;  1EG3 A;  2XP7 A;  3OOB A;  4GLX A;  2QRV A;  3LE4 A;  1EG4 A;  5E64 A;  2YSI A;  2YSB A;  1I5H W;  2JXW A;  1RP5 A;  2DK7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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