2M8JA

Structure of pin1 ww domain phospho-mimic s16e
Total Genus 3
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
3
sequence length
43
structure length
43
Chain Sequence
GLEHMADEEKLPPGWEKRMERSSGRVYYFNHITNASQWERPSG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
publication title Molecular crowding drives active Pin1 into nonspecific complexes with endogenous proteins prior to substrate recognition.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Isomerase
total genus 3
structure length 43
sequence length 43
ec nomenclature ec 5.2.1.8: Peptidylprolyl isomerase.
pdb deposition date 2013-05-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00397 WW WW domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.70.10 Mainly Beta Single Sheet Ubiquitin Ligase Nedd4; Chain: W; Ubiquitin Ligase Nedd4; Chain: W; 2m8jA01
2YSHA 3LE4A 4E5RA 3KAIA 2XP7A 1PINA 3KAFA 3TC5A 3KAGA 1WR7A 3M7NA 1NMVA 2DK7A 2ZQUA 2MDIA 3ODKA 2L4JA 2E45A 2XP9A 2XP6A 2ITKA 2ZQTA 2DK1A 4U84A 2KXQA 2M3OW 2Q5AA 1TK7A 1EG4A 2ZAJA 1K9QA 2JV4A 2F21A 2BA1A 2ZR4A 2LAJA 1F8AB 4REXA 3CNGA 1JMQA 3TDBA 3TCZA 2ZR5A 2JXWA 4U85A 1O6WA 1ZCNA 4U86A 3KCEA 2XP8A 2YSFA 2M8IA 2YSIA 2XPAA 1WMVA 3L4HA 1K9RA 2DWVA 2EZ5W 2JMFA 3KABA 3OOBA 2RE3A 2XPBA 5CQ2A 1EG3A 3KAHA 2DJYA 2XP3A 2ZR6A 2YSGA 2M8JA 2ZQSA 2DMVA 5AHTA 1I5HW 2ZQVA 3M85A 4QIBA 1YW5A 3KADA 3WH0A 2XP4A 2YSBA 2XP5A 3NTPA 2JX8A
chains in the Genus database with same CATH superfamily
1RP5A 2YSHA 3LE4A 4E5RA 3KAIA 2XP7A 1PINA 3KAFA 5E5WA 1TR8A 3TC5A 3KAGA 1WR7A 3M7NA 1NMVA 2DK7A 2ZQUA 2MDIA 5U47A 3MCBA 3ODKA 2L4JA 2E45A 2XP9A 2XP6A 2ITKA 2ZQTA 3MCBB 2DK1A 2WAEA 4U84A 2KXQA 2M3OW 2OWOA 2YAJB 2Q5AA 1TK7A 1EG4A 2ZAJA 1K9QA 4GLXA 2JV4A 2F21A 2BA1A 2ZR4A 2LAJA 1FLCA 1F8AB 4REXA 3CNGA 1JMQA 3TDBA 3TCZA 2ZR5A 2WADA 5E66A 2JXWA 4U85A 1O6WA 3FS8A 1ZCNA 4U86A 3FSBA 3KCEA 2XP8A 2YSFA 2M8IA 2YSIA 3FSCA 2XPAA 1WMVA 3L4HA 5E65A 2QRVA 1K9RA 2DWVA 2EZ5W 2JMFA 3PQHA 3KABA 3OOBA 3MQHA 2RE3A 2XPBA 5CQ2A 1EG3A 3KAHA 2DJYA 2XP3A 4A0UA 2ZR6A 2YSGA 2M8JA 3MQGA 2ZQSA 2DMVA 3LKXA 5AHTA 2Y8NB 1I5HW 2ZQVA 3M85A 4QIBA 1YW5A 3KADA 3LKXB 3WH0A 2XP4A 2YSBA 5E64A 2XP5A 3NTPA 2JX8A 4A0TA 5E62A
chains in the Genus database with same CATH topology
1RP5A 2YSHA 3LE4A 4E5RA 3KAIA 2XP7A 1PINA 3KAFA 5E5WA 1TR8A 3TC5A 3KAGA 1WR7A 3M7NA 1NMVA 2DK7A 2ZQUA 2MDIA 5U47A 3MCBA 3ODKA 2L4JA 2E45A 2XP9A 2XP6A 2ITKA 2ZQTA 3MCBB 2DK1A 2WAEA 4U84A 2KXQA 2M3OW 2OWOA 2YAJB 2Q5AA 1TK7A 1EG4A 2ZAJA 1K9QA 4GLXA 2JV4A 2F21A 2BA1A 2ZR4A 2LAJA 1FLCA 1F8AB 4REXA 3CNGA 1JMQA 3TDBA 3TCZA 2ZR5A 2WADA 5E66A 2JXWA 4U85A 1O6WA 3FS8A 1ZCNA 4U86A 3FSBA 3KCEA 2XP8A 2YSFA 2M8IA 2YSIA 3FSCA 2XPAA 1WMVA 3L4HA 5E65A 2QRVA 1K9RA 2DWVA 2EZ5W 2JMFA 3PQHA 3KABA 3OOBA 3MQHA 2RE3A 2XPBA 5CQ2A 1EG3A 3KAHA 2DJYA 2XP3A 4A0UA 2ZR6A 2YSGA 2M8JA 3MQGA 2ZQSA 2DMVA 3LKXA 5AHTA 2Y8NB 1I5HW 2ZQVA 3M85A 4QIBA 1YW5A 3KADA 3LKXB 3WH0A 2XP4A 2YSBA 5E64A 2XP5A 3NTPA 2JX8A 4A0TA 5E62A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2YSH A;  3LE4 A;  4E5R A;  3KAI A;  2XP7 A;  1PIN A;  3KAF A;  3TC5 A;  3KAG A;  1WR7 A;  3M7N A;  1NMV A;  2DK7 A;  2ZQU A;  2MDI A;  3ODK A;  2L4J A;  2E45 A;  2XP9 A;  2XP6 A;  2ITK A;  2ZQT A;  2DK1 A;  4U84 A;  2KXQ A;  2M3O W;  2Q5A A;  1TK7 A;  1EG4 A;  2ZAJ A;  1K9Q A;  2JV4 A;  2F21 A;  2BA1 A;  2ZR4 A;  2LAJ A;  1F8A B;  4REX A;  3CNG A;  1JMQ A;  3TDB A;  3TCZ A;  2ZR5 A;  2JXW A;  4U85 A;  1O6W A;  1ZCN A;  4U86 A;  3KCE A;  2XP8 A;  2YSF A;  2M8I A;  2YSI A;  2XPA A;  1WMV A;  3L4H A;  1K9R A;  2DWV A;  2EZ5 W;  2JMF A;  3KAB A;  3OOB A;  2RE3 A;  2XPB A;  5CQ2 A;  1EG3 A;  3KAH A;  2DJY A;  2XP3 A;  2ZR6 A;  2YSG A;  2M8J A;  2ZQS A;  2DMV A;  5AHT A;  1I5H W;  2ZQV A;  3M85 A;  4QIB A;  1YW5 A;  3KAD A;  3WH0 A;  2XP4 A;  2YSB A;  2XP5 A;  3NTP A;  2JX8 A; 
#chains in the Genus database with same CATH topology
 1RP5 A;  2YSH A;  3LE4 A;  4E5R A;  3KAI A;  2XP7 A;  1PIN A;  3KAF A;  5E5W A;  1TR8 A;  3TC5 A;  3KAG A;  1WR7 A;  3M7N A;  1NMV A;  2DK7 A;  2ZQU A;  2MDI A;  5U47 A;  3MCB A;  3ODK A;  2L4J A;  2E45 A;  2XP9 A;  2XP6 A;  2ITK A;  2ZQT A;  3MCB B;  2DK1 A;  2WAE A;  4U84 A;  2KXQ A;  2M3O W;  2OWO A;  2YAJ B;  2Q5A A;  1TK7 A;  1EG4 A;  2ZAJ A;  1K9Q A;  4GLX A;  2JV4 A;  2F21 A;  2BA1 A;  2ZR4 A;  2LAJ A;  1FLC A;  1F8A B;  4REX A;  3CNG A;  1JMQ A;  3TDB A;  3TCZ A;  2ZR5 A;  2WAD A;  5E66 A;  2JXW A;  4U85 A;  1O6W A;  3FS8 A;  1ZCN A;  4U86 A;  3FSB A;  3KCE A;  2XP8 A;  2YSF A;  2M8I A;  2YSI A;  3FSC A;  2XPA A;  1WMV A;  3L4H A;  5E65 A;  2QRV A;  1K9R A;  2DWV A;  2EZ5 W;  2JMF A;  3PQH A;  3KAB A;  3OOB A;  3MQH A;  2RE3 A;  2XPB A;  5CQ2 A;  1EG3 A;  3KAH A;  2DJY A;  2XP3 A;  4A0U A;  2ZR6 A;  2YSG A;  2M8J A;  3MQG A;  2ZQS A;  2DMV A;  3LKX A;  5AHT A;  2Y8N B;  1I5H W;  2ZQV A;  3M85 A;  4QIB A;  1YW5 A;  3KAD A;  3LKX B;  3WH0 A;  2XP4 A;  2YSB A;  5E64 A;  2XP5 A;  3NTP A;  2JX8 A;  4A0T A;  5E62 A; 
#chains in the Genus database with same CATH homology
 1RP5 A;  2YSH A;  3LE4 A;  4E5R A;  3KAI A;  2XP7 A;  1PIN A;  3KAF A;  5E5W A;  1TR8 A;  3TC5 A;  3KAG A;  1WR7 A;  3M7N A;  1NMV A;  2DK7 A;  2ZQU A;  2MDI A;  5U47 A;  3MCB A;  3ODK A;  2L4J A;  2E45 A;  2XP9 A;  2XP6 A;  2ITK A;  2ZQT A;  3MCB B;  2DK1 A;  2WAE A;  4U84 A;  2KXQ A;  2M3O W;  2OWO A;  2YAJ B;  2Q5A A;  1TK7 A;  1EG4 A;  2ZAJ A;  1K9Q A;  4GLX A;  2JV4 A;  2F21 A;  2BA1 A;  2ZR4 A;  2LAJ A;  1FLC A;  1F8A B;  4REX A;  3CNG A;  1JMQ A;  3TDB A;  3TCZ A;  2ZR5 A;  2WAD A;  5E66 A;  2JXW A;  4U85 A;  1O6W A;  3FS8 A;  1ZCN A;  4U86 A;  3FSB A;  3KCE A;  2XP8 A;  2YSF A;  2M8I A;  2YSI A;  3FSC A;  2XPA A;  1WMV A;  3L4H A;  5E65 A;  2QRV A;  1K9R A;  2DWV A;  2EZ5 W;  2JMF A;  3PQH A;  3KAB A;  3OOB A;  3MQH A;  2RE3 A;  2XPB A;  5CQ2 A;  1EG3 A;  3KAH A;  2DJY A;  2XP3 A;  4A0U A;  2ZR6 A;  2YSG A;  2M8J A;  3MQG A;  2ZQS A;  2DMV A;  3LKX A;  5AHT A;  2Y8N B;  1I5H W;  2ZQV A;  3M85 A;  4QIB A;  1YW5 A;  3KAD A;  3LKX B;  3WH0 A;  2XP4 A;  2YSB A;  5E64 A;  2XP5 A;  3NTP A;  2JX8 A;  4A0T A;  5E62 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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