5E66A

The complex structure of hemagglutinin-esterase-fusion mutant protein from the influenza d virus with receptor analog 9-n-ac-sia
Total Genus 109
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
109
sequence length
427
structure length
424
Chain Sequence
ELICIVQRVNESFSLHSGFGGNVYSMKTEPMTGFTNVTKGASVINQKDWIGFGDSRTDLTNDQFPASSDVPLAVAKKFRSLSGASLMLSAFGPPGKVDYLYQGCGKEKVFYEGVNWSPEAGIDCFGSNWTQTKKDFYSRIYEAARSSTCMTLVNSLDTKISSTTATAGTASSCSSSWMKSPLWYAESSVNPPQVCGTEQSATFTLPTSFGIYKCNKHVVQLCYFVYENKAKFNTFGCGDYYQNYYDGNGNLIGGMDNRVAAYRGIANAGVKIECPSKILNPGTYSIKSTPRFLLVPKRSYCFDTDGGYPIQVVQSEWSASRRSDNATEEACLQTEGCIFIKKTTPYVGEADDNHGDIEMRQLLSGLGNNDTVCVSQSGYTKGETPFVKDYLSPPKYGRCQLKTDSGRIPTLPSGLIIPQAGTDS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title An Open Receptor-Binding Cavity of Hemagglutinin-Esterase-Fusion Glycoprotein from Newly-Identified Influenza D Virus: Basis for Its Broad Cell Tropism
pubmed doi rcsb
molecule tags Hydrolase
source organism Influenza d virus (d/swine/oklahoma/1334/2011)
molecule keywords Hemagglutinin-esterase
total genus 109
structure length 424
sequence length 427
ec nomenclature
pdb deposition date 2015-10-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02710 Hema_HEFG Hemagglutinin domain of haemagglutinin-esterase-fusion glycoprotein
A PF03996 Hema_esterase Hemagglutinin esterase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.70.20 Mainly Beta Single Sheet Ubiquitin Ligase Nedd4; Chain: W; Ubiquitin Ligase Nedd4; Chain: W; 5e66A01
5E5WA 1FLCA 5E65A 5E62A 5E66A 5E64A
chains in the Genus database with same CATH superfamily
2M8IA 2WADA 2XPBA 5E5WA 2ZR6A 2XP9A 4U85A 5E66A 2ZQUA 4REXA 2XP5A 1YW5A 4QIBA 5AHTA 2DMVA 5CQ2A 2YAJB 2XP7A 2RE3A 3TDBA 2Q5AA 3M85A 1K9QA 3NTPA 3KAFA 2XP6A 3TC5A 3OOBA 1PINA 2Y8NB 2ITKA 1I5HW 4GLXA 3KAIA 2DK7A 2JV4A 3KABA 3MCBB 1JMQA 2ZQTA 2KXQA 2QRVA 1FLCA 2EZ5W 3WH0A 2YSFA 2JXWA 4E5RA 1K9RA 2BA1A 2F21A 3KAGA 2ZR5A 4U84A 2XP4A 4U86A 2JX8A 2DJYA 2L4JA 3MQGA 3FSCA 3MQHA 3KAHA 1NMVA 1ZCNA 3TCZA 3FSBA 1O6WA 5E62A 2ZQVA 2XP3A 1TR8A 3ODKA 2OWOA 1WMVA 1WR7A 2LAJA 3L4HA 3FS8A 4A0TA 3LKXB 2XP8A 3MCBA 2YSBA 1EG3A 3KCEA 2YSHA 3M7NA 5U47A 2MDIA 2YSGA 2ZR4A 2YSIA 2JMFA 2DWVA 1TK7A 3PQHA 2WAEA 5E65A 2E45A 2M3OW 2ZAJA 1RP5A 2DK1A 1F8AB 3CNGA 3KADA 5E64A 2M8JA 4A0UA 2XPAA 3LKXA 3LE4A 2ZQSA 1EG4A
chains in the Genus database with same CATH topology
2M8IA 2WADA 2XPBA 5E5WA 2ZR6A 2XP9A 4U85A 5E66A 2ZQUA 4REXA 2XP5A 1YW5A 4QIBA 5AHTA 2DMVA 5CQ2A 2YAJB 2XP7A 2RE3A 3TDBA 2Q5AA 3M85A 1K9QA 3NTPA 3KAFA 2XP6A 3TC5A 3OOBA 1PINA 2Y8NB 2ITKA 1I5HW 4GLXA 3KAIA 2DK7A 2JV4A 3KABA 3MCBB 1JMQA 2ZQTA 2KXQA 2QRVA 1FLCA 2EZ5W 3WH0A 2YSFA 2JXWA 4E5RA 1K9RA 2BA1A 2F21A 3KAGA 2ZR5A 4U84A 2XP4A 4U86A 2JX8A 2DJYA 2L4JA 3MQGA 3FSCA 3MQHA 3KAHA 1NMVA 1ZCNA 3TCZA 3FSBA 1O6WA 5E62A 2ZQVA 2XP3A 1TR8A 3ODKA 2OWOA 1WMVA 1WR7A 2LAJA 3L4HA 3FS8A 4A0TA 3LKXB 2XP8A 3MCBA 2YSBA 1EG3A 3KCEA 2YSHA 3M7NA 5U47A 2MDIA 2YSGA 2ZR4A 2YSIA 2JMFA 2DWVA 1TK7A 3PQHA 2WAEA 5E65A 2E45A 2M3OW 2ZAJA 1RP5A 2DK1A 1F8AB 3CNGA 3KADA 5E64A 2M8JA 4A0UA 2XPAA 3LKXA 3LE4A 2ZQSA 1EG4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5E5W A;  1FLC A;  5E65 A;  5E62 A;  5E66 A;  5E64 A; 
#chains in the Genus database with same CATH topology
 2M8I A;  2WAD A;  2XPB A;  5E5W A;  2ZR6 A;  2XP9 A;  4U85 A;  5E66 A;  2ZQU A;  4REX A;  2XP5 A;  1YW5 A;  4QIB A;  5AHT A;  2DMV A;  5CQ2 A;  2YAJ B;  2XP7 A;  2RE3 A;  3TDB A;  2Q5A A;  3M85 A;  1K9Q A;  3NTP A;  3KAF A;  2XP6 A;  3TC5 A;  3OOB A;  1PIN A;  2Y8N B;  2ITK A;  1I5H W;  4GLX A;  3KAI A;  2DK7 A;  2JV4 A;  3KAB A;  3MCB B;  1JMQ A;  2ZQT A;  2KXQ A;  2QRV A;  1FLC A;  2EZ5 W;  3WH0 A;  2YSF A;  2JXW A;  4E5R A;  1K9R A;  2BA1 A;  2F21 A;  3KAG A;  2ZR5 A;  4U84 A;  2XP4 A;  4U86 A;  2JX8 A;  2DJY A;  2L4J A;  3MQG A;  3FSC A;  3MQH A;  3KAH A;  1NMV A;  1ZCN A;  3TCZ A;  3FSB A;  1O6W A;  5E62 A;  2ZQV A;  2XP3 A;  1TR8 A;  3ODK A;  2OWO A;  1WMV A;  1WR7 A;  2LAJ A;  3L4H A;  3FS8 A;  4A0T A;  3LKX B;  2XP8 A;  3MCB A;  2YSB A;  1EG3 A;  3KCE A;  2YSH A;  3M7N A;  5U47 A;  2MDI A;  2YSG A;  2ZR4 A;  2YSI A;  2JMF A;  2DWV A;  1TK7 A;  3PQH A;  2WAE A;  5E65 A;  2E45 A;  2M3O W;  2ZAJ A;  1RP5 A;  2DK1 A;  1F8A B;  3CNG A;  3KAD A;  5E64 A;  2M8J A;  4A0U A;  2XPA A;  3LKX A;  3LE4 A;  2ZQS A;  1EG4 A; 
#chains in the Genus database with same CATH homology
 2M8I A;  2WAD A;  2XPB A;  5E5W A;  2ZR6 A;  2XP9 A;  4U85 A;  5E66 A;  2ZQU A;  4REX A;  2XP5 A;  1YW5 A;  4QIB A;  5AHT A;  2DMV A;  5CQ2 A;  2YAJ B;  2XP7 A;  2RE3 A;  3TDB A;  2Q5A A;  3M85 A;  1K9Q A;  3NTP A;  3KAF A;  2XP6 A;  3TC5 A;  3OOB A;  1PIN A;  2Y8N B;  2ITK A;  1I5H W;  4GLX A;  3KAI A;  2DK7 A;  2JV4 A;  3KAB A;  3MCB B;  1JMQ A;  2ZQT A;  2KXQ A;  2QRV A;  1FLC A;  2EZ5 W;  3WH0 A;  2YSF A;  2JXW A;  4E5R A;  1K9R A;  2BA1 A;  2F21 A;  3KAG A;  2ZR5 A;  4U84 A;  2XP4 A;  4U86 A;  2JX8 A;  2DJY A;  2L4J A;  3MQG A;  3FSC A;  3MQH A;  3KAH A;  1NMV A;  1ZCN A;  3TCZ A;  3FSB A;  1O6W A;  5E62 A;  2ZQV A;  2XP3 A;  1TR8 A;  3ODK A;  2OWO A;  1WMV A;  1WR7 A;  2LAJ A;  3L4H A;  3FS8 A;  4A0T A;  3LKX B;  2XP8 A;  3MCB A;  2YSB A;  1EG3 A;  3KCE A;  2YSH A;  3M7N A;  5U47 A;  2MDI A;  2YSG A;  2ZR4 A;  2YSI A;  2JMF A;  2DWV A;  1TK7 A;  3PQH A;  2WAE A;  5E65 A;  2E45 A;  2M3O W;  2ZAJ A;  1RP5 A;  2DK1 A;  1F8A B;  3CNG A;  3KAD A;  5E64 A;  2M8J A;  4A0U A;  2XPA A;  3LKX A;  3LE4 A;  2ZQS A;  1EG4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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