2DJYA

Solution structure of smurf2 ww3 domain-smad7 py peptide complex
Total Genus 3
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
3
sequence length
42
structure length
42
Chain Sequence
GPLGSGPLPPGWEIRNTATGRVYFVDHNNRTTQFTDPRLSAN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title An Expanded WW Domain Recognition Motif Revealed by the Interaction between Smad7 and the E3 Ubiquitin Ligase Smurf2.
pubmed doi rcsb
molecule tags Ligase/signaling protein
source organism Homo sapiens
molecule keywords Smad ubiquitination regulatory factor 2
total genus 3
structure length 42
sequence length 42
ec nomenclature ec 2.3.2.26: HECT-type E3 ubiquitin transferase.
pdb deposition date 2006-04-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00397 WW WW domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.70.10 Mainly Beta Single Sheet Ubiquitin Ligase Nedd4; Chain: W; Ubiquitin Ligase Nedd4; Chain: W; 2djyA01
3CNGA 3WH0A 3TDBA 2XP8A 2F21A 2MDIA 1WR7A 2JV4A 1TK7A 2DWVA 4U84A 1ZCNA 2XP4A 1YW5A 2XPAA 2ZAJA 2YSGA 2LAJA 2JXWA 2DMVA 3KAGA 1NMVA 4U86A 1F8AB 1K9RA 2JX8A 2M8JA 5CQ2A 4QIBA 2Q5AA 2XP3A 3KAFA 2BA1A 1JMQA 2ZQUA 2RE3A 2ZR6A 2YSBA 2DJYA 3TC5A 1EG4A 4U85A 3KABA 2XP5A 2E45A 2XPBA 1WMVA 1K9QA 2ZQVA 3OOBA 2ZR5A 1O6WA 4REXA 5AHTA 1EG3A 2XP9A 2DK7A 3LE4A 2L4JA 2YSIA 2XP7A 3KAIA 2YSHA 4E5RA 1PINA 3KAHA 2EZ5W 3L4HA 2JMFA 3M85A 2M3OW 2YSFA 2DK1A 2ZQSA 2ITKA 2ZR4A 3KCEA 3TCZA 3KADA 1I5HW 2ZQTA 3ODKA 2XP6A 3NTPA 3M7NA 2KXQA 2M8IA
chains in the Genus database with same CATH superfamily
3CNGA 3WH0A 5E66A 3TDBA 2XP8A 2F21A 3LKXB 2MDIA 1WR7A 2JV4A 1TK7A 5U47A 5E5WA 2DWVA 4U84A 1ZCNA 2XP4A 1YW5A 2XPAA 2ZAJA 1FLCA 3MCBA 4A0UA 2YSGA 5E65A 2LAJA 2JXWA 2DMVA 2OWOA 3KAGA 1NMVA 4U86A 1F8AB 1K9RA 2JX8A 1RP5A 2M8JA 3FS8A 4QIBA 3KAFA 2Q5AA 2WADA 2XP3A 2BA1A 3PQHA 5CQ2A 1JMQA 2ZQUA 2RE3A 2ZR6A 2YSBA 2DJYA 3MCBB 3TC5A 1EG4A 4U85A 3KABA 2XP5A 2Y8NB 2E45A 2XPBA 3FSBA 1WMVA 3FSCA 1K9QA 2ZQVA 3OOBA 2ZR5A 1O6WA 4REXA 5AHTA 1EG3A 2WAEA 2XP9A 2DK7A 5E62A 3LE4A 4GLXA 2L4JA 2YSIA 2XP7A 3KAIA 2QRVA 2YSHA 5E64A 3LKXA 4E5RA 2YAJB 1PINA 3KAHA 2EZ5W 3L4HA 2JMFA 3M85A 3MQGA 2M3OW 2YSFA 2DK1A 1TR8A 2ZQSA 2ITKA 2ZR4A 3KCEA 3TCZA 3KADA 3MQHA 1I5HW 2ZQTA 3ODKA 2XP6A 3NTPA 3M7NA 2KXQA 4A0TA 2M8IA
chains in the Genus database with same CATH topology
3CNGA 3WH0A 5E66A 3TDBA 2XP8A 2F21A 3LKXB 2MDIA 1WR7A 2JV4A 1TK7A 5U47A 5E5WA 2DWVA 4U84A 1ZCNA 2XP4A 1YW5A 2XPAA 2ZAJA 1FLCA 3MCBA 4A0UA 2YSGA 5E65A 2LAJA 2JXWA 2DMVA 2OWOA 3KAGA 1NMVA 4U86A 1F8AB 1K9RA 2JX8A 1RP5A 2M8JA 3FS8A 4QIBA 3KAFA 2Q5AA 2WADA 2XP3A 2BA1A 3PQHA 5CQ2A 1JMQA 2ZQUA 2RE3A 2ZR6A 2YSBA 2DJYA 3MCBB 3TC5A 1EG4A 4U85A 3KABA 2XP5A 2Y8NB 2E45A 2XPBA 3FSBA 1WMVA 3FSCA 1K9QA 2ZQVA 3OOBA 2ZR5A 1O6WA 4REXA 5AHTA 1EG3A 2WAEA 2XP9A 2DK7A 5E62A 3LE4A 4GLXA 2L4JA 2YSIA 2XP7A 3KAIA 2QRVA 2YSHA 5E64A 3LKXA 4E5RA 2YAJB 1PINA 3KAHA 2EZ5W 3L4HA 2JMFA 3M85A 3MQGA 2M3OW 2YSFA 2DK1A 1TR8A 2ZQSA 2ITKA 2ZR4A 3KCEA 3TCZA 3KADA 3MQHA 1I5HW 2ZQTA 3ODKA 2XP6A 3NTPA 3M7NA 2KXQA 4A0TA 2M8IA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CNG A;  3WH0 A;  3TDB A;  2XP8 A;  2F21 A;  2MDI A;  1WR7 A;  2JV4 A;  1TK7 A;  2DWV A;  4U84 A;  1ZCN A;  2XP4 A;  1YW5 A;  2XPA A;  2ZAJ A;  2YSG A;  2LAJ A;  2JXW A;  2DMV A;  3KAG A;  1NMV A;  4U86 A;  1F8A B;  1K9R A;  2JX8 A;  2M8J A;  5CQ2 A;  4QIB A;  2Q5A A;  2XP3 A;  3KAF A;  2BA1 A;  1JMQ A;  2ZQU A;  2RE3 A;  2ZR6 A;  2YSB A;  2DJY A;  3TC5 A;  1EG4 A;  4U85 A;  3KAB A;  2XP5 A;  2E45 A;  2XPB A;  1WMV A;  1K9Q A;  2ZQV A;  3OOB A;  2ZR5 A;  1O6W A;  4REX A;  5AHT A;  1EG3 A;  2XP9 A;  2DK7 A;  3LE4 A;  2L4J A;  2YSI A;  2XP7 A;  3KAI A;  2YSH A;  4E5R A;  1PIN A;  3KAH A;  2EZ5 W;  3L4H A;  2JMF A;  3M85 A;  2M3O W;  2YSF A;  2DK1 A;  2ZQS A;  2ITK A;  2ZR4 A;  3KCE A;  3TCZ A;  3KAD A;  1I5H W;  2ZQT A;  3ODK A;  2XP6 A;  3NTP A;  3M7N A;  2KXQ A;  2M8I A; 
#chains in the Genus database with same CATH topology
 3CNG A;  3WH0 A;  5E66 A;  3TDB A;  2XP8 A;  2F21 A;  3LKX B;  2MDI A;  1WR7 A;  2JV4 A;  1TK7 A;  5U47 A;  5E5W A;  2DWV A;  4U84 A;  1ZCN A;  2XP4 A;  1YW5 A;  2XPA A;  2ZAJ A;  1FLC A;  3MCB A;  4A0U A;  2YSG A;  5E65 A;  2LAJ A;  2JXW A;  2DMV A;  2OWO A;  3KAG A;  1NMV A;  4U86 A;  1F8A B;  1K9R A;  2JX8 A;  1RP5 A;  2M8J A;  3FS8 A;  4QIB A;  3KAF A;  2Q5A A;  2WAD A;  2XP3 A;  2BA1 A;  3PQH A;  5CQ2 A;  1JMQ A;  2ZQU A;  2RE3 A;  2ZR6 A;  2YSB A;  2DJY A;  3MCB B;  3TC5 A;  1EG4 A;  4U85 A;  3KAB A;  2XP5 A;  2Y8N B;  2E45 A;  2XPB A;  3FSB A;  1WMV A;  3FSC A;  1K9Q A;  2ZQV A;  3OOB A;  2ZR5 A;  1O6W A;  4REX A;  5AHT A;  1EG3 A;  2WAE A;  2XP9 A;  2DK7 A;  5E62 A;  3LE4 A;  4GLX A;  2L4J A;  2YSI A;  2XP7 A;  3KAI A;  2QRV A;  2YSH A;  5E64 A;  3LKX A;  4E5R A;  2YAJ B;  1PIN A;  3KAH A;  2EZ5 W;  3L4H A;  2JMF A;  3M85 A;  3MQG A;  2M3O W;  2YSF A;  2DK1 A;  1TR8 A;  2ZQS A;  2ITK A;  2ZR4 A;  3KCE A;  3TCZ A;  3KAD A;  3MQH A;  1I5H W;  2ZQT A;  3ODK A;  2XP6 A;  3NTP A;  3M7N A;  2KXQ A;  4A0T A;  2M8I A; 
#chains in the Genus database with same CATH homology
 3CNG A;  3WH0 A;  5E66 A;  3TDB A;  2XP8 A;  2F21 A;  3LKX B;  2MDI A;  1WR7 A;  2JV4 A;  1TK7 A;  5U47 A;  5E5W A;  2DWV A;  4U84 A;  1ZCN A;  2XP4 A;  1YW5 A;  2XPA A;  2ZAJ A;  1FLC A;  3MCB A;  4A0U A;  2YSG A;  5E65 A;  2LAJ A;  2JXW A;  2DMV A;  2OWO A;  3KAG A;  1NMV A;  4U86 A;  1F8A B;  1K9R A;  2JX8 A;  1RP5 A;  2M8J A;  3FS8 A;  4QIB A;  3KAF A;  2Q5A A;  2WAD A;  2XP3 A;  2BA1 A;  3PQH A;  5CQ2 A;  1JMQ A;  2ZQU A;  2RE3 A;  2ZR6 A;  2YSB A;  2DJY A;  3MCB B;  3TC5 A;  1EG4 A;  4U85 A;  3KAB A;  2XP5 A;  2Y8N B;  2E45 A;  2XPB A;  3FSB A;  1WMV A;  3FSC A;  1K9Q A;  2ZQV A;  3OOB A;  2ZR5 A;  1O6W A;  4REX A;  5AHT A;  1EG3 A;  2WAE A;  2XP9 A;  2DK7 A;  5E62 A;  3LE4 A;  4GLX A;  2L4J A;  2YSI A;  2XP7 A;  3KAI A;  2QRV A;  2YSH A;  5E64 A;  3LKX A;  4E5R A;  2YAJ B;  1PIN A;  3KAH A;  2EZ5 W;  3L4H A;  2JMF A;  3M85 A;  3MQG A;  2M3O W;  2YSF A;  2DK1 A;  1TR8 A;  2ZQS A;  2ITK A;  2ZR4 A;  3KCE A;  3TCZ A;  3KAD A;  3MQH A;  1I5H W;  2ZQT A;  3ODK A;  2XP6 A;  3NTP A;  3M7N A;  2KXQ A;  4A0T A;  2M8I A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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