1K9RA

Yap65 ww domain complexed to acetyl-plppy
Total Genus 3
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
3
sequence length
40
structure length
40
Chain Sequence
FEIPDDVPLPAGWEMAKTSSGQRYFLNHIDQTTTWQDPRK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structures of the YAP65 WW domain and the variant L30 K in complex with the peptides GTPPPPYTVG, N-(n-octyl)-GPPPY and PLPPY and the application of peptide libraries reveal a minimal binding epitope.
pubmed doi rcsb
molecule tags Structural protein
molecule keywords 65 kDa Yes-associated protein
total genus 3
structure length 40
sequence length 40
ec nomenclature
pdb deposition date 2001-10-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00397 WW WW domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.70.10 Mainly Beta Single Sheet Ubiquitin Ligase Nedd4; Chain: W; Ubiquitin Ligase Nedd4; Chain: W; 1k9rA00
4REXA 2DK1A 2ZQTA 2ZAJA 2Q5AA 2JMFA 2DMVA 5CQ2A 2BA1A 3L4HA 3NTPA 3KAGA 2LAJA 2ZR6A 3CNGA 4U86A 1WR7A 1EG4A 2XP3A 2ZR5A 1ZCNA 3KAFA 1JMQA 3KAIA 2XP9A 2F21A 3M7NA 2L4JA 1YW5A 2KXQA 2ZQVA 2ITKA 3M85A 2ZR4A 4U85A 2YSBA 3TDBA 3WH0A 3TC5A 2YSIA 2XP5A 1I5HW 2YSFA 2E45A 1PINA 3KCEA 1F8AB 2XP7A 2JV4A 2M3OW 2M8JA 2YSGA 4QIBA 2ZQSA 2EZ5W 1EG3A 1K9RA 2XPAA 3KAHA 2DK7A 2XPBA 3OOBA 2MDIA 3LE4A 5AHTA 2RE3A 4E5RA 2YSHA 1TK7A 4U84A 1NMVA 3KADA 3TCZA 2M8IA 2XP8A 1O6WA 3KABA 2XP4A 1WMVA 2JXWA 1K9QA 2DWVA 3ODKA 2ZQUA 2DJYA 2XP6A 2JX8A
chains in the Genus database with same CATH superfamily
4REXA 2DK1A 2ZQTA 2ZAJA 2Y8NB 3MQGA 2Q5AA 2JMFA 2DMVA 3PQHA 5CQ2A 1RP5A 2BA1A 1FLCA 3L4HA 3NTPA 2YAJB 3KAGA 2LAJA 2ZR6A 4GLXA 3CNGA 3LKXB 4U86A 5U47A 1WR7A 1EG4A 2XP3A 5E66A 2ZR5A 1ZCNA 3KAFA 1JMQA 3KAIA 2XP9A 2F21A 3M7NA 2L4JA 1YW5A 2KXQA 2OWOA 3MCBA 2ZQVA 4A0UA 2ITKA 3M85A 2ZR4A 4U85A 2YSBA 3TDBA 3FS8A 3WH0A 3TC5A 2YSIA 2XP5A 5E5WA 1I5HW 2YSFA 5E62A 2E45A 1PINA 2WAEA 3FSCA 3KCEA 1F8AB 2XP7A 2JV4A 2M3OW 2M8JA 2YSGA 4QIBA 2ZQSA 2EZ5W 1EG3A 3MQHA 1K9RA 2XPAA 3KAHA 2QRVA 2DK7A 4A0TA 2XPBA 3LKXA 3OOBA 2MDIA 3LE4A 5AHTA 2RE3A 4E5RA 2YSHA 1TR8A 5E65A 1TK7A 4U84A 1NMVA 3KADA 3TCZA 2M8IA 2XP8A 1O6WA 3MCBB 3KABA 2XP4A 1WMVA 2JXWA 3FSBA 1K9QA 2DWVA 3ODKA 2ZQUA 2WADA 2DJYA 5E64A 2XP6A 2JX8A
chains in the Genus database with same CATH topology
4REXA 2DK1A 2ZQTA 2ZAJA 2Y8NB 3MQGA 2Q5AA 2JMFA 2DMVA 3PQHA 5CQ2A 1RP5A 2BA1A 1FLCA 3L4HA 3NTPA 2YAJB 3KAGA 2LAJA 2ZR6A 4GLXA 3CNGA 3LKXB 4U86A 5U47A 1WR7A 1EG4A 2XP3A 5E66A 2ZR5A 1ZCNA 3KAFA 1JMQA 3KAIA 2XP9A 2F21A 3M7NA 2L4JA 1YW5A 2KXQA 2OWOA 3MCBA 2ZQVA 4A0UA 2ITKA 3M85A 2ZR4A 4U85A 2YSBA 3TDBA 3FS8A 3WH0A 3TC5A 2YSIA 2XP5A 5E5WA 1I5HW 2YSFA 5E62A 2E45A 1PINA 2WAEA 3FSCA 3KCEA 1F8AB 2XP7A 2JV4A 2M3OW 2M8JA 2YSGA 4QIBA 2ZQSA 2EZ5W 1EG3A 3MQHA 1K9RA 2XPAA 3KAHA 2QRVA 2DK7A 4A0TA 2XPBA 3LKXA 3OOBA 2MDIA 3LE4A 5AHTA 2RE3A 4E5RA 2YSHA 1TR8A 5E65A 1TK7A 4U84A 1NMVA 3KADA 3TCZA 2M8IA 2XP8A 1O6WA 3MCBB 3KABA 2XP4A 1WMVA 2JXWA 3FSBA 1K9QA 2DWVA 3ODKA 2ZQUA 2WADA 2DJYA 5E64A 2XP6A 2JX8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4REX A;  2DK1 A;  2ZQT A;  2ZAJ A;  2Q5A A;  2JMF A;  2DMV A;  5CQ2 A;  2BA1 A;  3L4H A;  3NTP A;  3KAG A;  2LAJ A;  2ZR6 A;  3CNG A;  4U86 A;  1WR7 A;  1EG4 A;  2XP3 A;  2ZR5 A;  1ZCN A;  3KAF A;  1JMQ A;  3KAI A;  2XP9 A;  2F21 A;  3M7N A;  2L4J A;  1YW5 A;  2KXQ A;  2ZQV A;  2ITK A;  3M85 A;  2ZR4 A;  4U85 A;  2YSB A;  3TDB A;  3WH0 A;  3TC5 A;  2YSI A;  2XP5 A;  1I5H W;  2YSF A;  2E45 A;  1PIN A;  3KCE A;  1F8A B;  2XP7 A;  2JV4 A;  2M3O W;  2M8J A;  2YSG A;  4QIB A;  2ZQS A;  2EZ5 W;  1EG3 A;  1K9R A;  2XPA A;  3KAH A;  2DK7 A;  2XPB A;  3OOB A;  2MDI A;  3LE4 A;  5AHT A;  2RE3 A;  4E5R A;  2YSH A;  1TK7 A;  4U84 A;  1NMV A;  3KAD A;  3TCZ A;  2M8I A;  2XP8 A;  1O6W A;  3KAB A;  2XP4 A;  1WMV A;  2JXW A;  1K9Q A;  2DWV A;  3ODK A;  2ZQU A;  2DJY A;  2XP6 A;  2JX8 A; 
#chains in the Genus database with same CATH topology
 4REX A;  2DK1 A;  2ZQT A;  2ZAJ A;  2Y8N B;  3MQG A;  2Q5A A;  2JMF A;  2DMV A;  3PQH A;  5CQ2 A;  1RP5 A;  2BA1 A;  1FLC A;  3L4H A;  3NTP A;  2YAJ B;  3KAG A;  2LAJ A;  2ZR6 A;  4GLX A;  3CNG A;  3LKX B;  4U86 A;  5U47 A;  1WR7 A;  1EG4 A;  2XP3 A;  5E66 A;  2ZR5 A;  1ZCN A;  3KAF A;  1JMQ A;  3KAI A;  2XP9 A;  2F21 A;  3M7N A;  2L4J A;  1YW5 A;  2KXQ A;  2OWO A;  3MCB A;  2ZQV A;  4A0U A;  2ITK A;  3M85 A;  2ZR4 A;  4U85 A;  2YSB A;  3TDB A;  3FS8 A;  3WH0 A;  3TC5 A;  2YSI A;  2XP5 A;  5E5W A;  1I5H W;  2YSF A;  5E62 A;  2E45 A;  1PIN A;  2WAE A;  3FSC A;  3KCE A;  1F8A B;  2XP7 A;  2JV4 A;  2M3O W;  2M8J A;  2YSG A;  4QIB A;  2ZQS A;  2EZ5 W;  1EG3 A;  3MQH A;  1K9R A;  2XPA A;  3KAH A;  2QRV A;  2DK7 A;  4A0T A;  2XPB A;  3LKX A;  3OOB A;  2MDI A;  3LE4 A;  5AHT A;  2RE3 A;  4E5R A;  2YSH A;  1TR8 A;  5E65 A;  1TK7 A;  4U84 A;  1NMV A;  3KAD A;  3TCZ A;  2M8I A;  2XP8 A;  1O6W A;  3MCB B;  3KAB A;  2XP4 A;  1WMV A;  2JXW A;  3FSB A;  1K9Q A;  2DWV A;  3ODK A;  2ZQU A;  2WAD A;  2DJY A;  5E64 A;  2XP6 A;  2JX8 A; 
#chains in the Genus database with same CATH homology
 4REX A;  2DK1 A;  2ZQT A;  2ZAJ A;  2Y8N B;  3MQG A;  2Q5A A;  2JMF A;  2DMV A;  3PQH A;  5CQ2 A;  1RP5 A;  2BA1 A;  1FLC A;  3L4H A;  3NTP A;  2YAJ B;  3KAG A;  2LAJ A;  2ZR6 A;  4GLX A;  3CNG A;  3LKX B;  4U86 A;  5U47 A;  1WR7 A;  1EG4 A;  2XP3 A;  5E66 A;  2ZR5 A;  1ZCN A;  3KAF A;  1JMQ A;  3KAI A;  2XP9 A;  2F21 A;  3M7N A;  2L4J A;  1YW5 A;  2KXQ A;  2OWO A;  3MCB A;  2ZQV A;  4A0U A;  2ITK A;  3M85 A;  2ZR4 A;  4U85 A;  2YSB A;  3TDB A;  3FS8 A;  3WH0 A;  3TC5 A;  2YSI A;  2XP5 A;  5E5W A;  1I5H W;  2YSF A;  5E62 A;  2E45 A;  1PIN A;  2WAE A;  3FSC A;  3KCE A;  1F8A B;  2XP7 A;  2JV4 A;  2M3O W;  2M8J A;  2YSG A;  4QIB A;  2ZQS A;  2EZ5 W;  1EG3 A;  3MQH A;  1K9R A;  2XPA A;  3KAH A;  2QRV A;  2DK7 A;  4A0T A;  2XPB A;  3LKX A;  3OOB A;  2MDI A;  3LE4 A;  5AHT A;  2RE3 A;  4E5R A;  2YSH A;  1TR8 A;  5E65 A;  1TK7 A;  4U84 A;  1NMV A;  3KAD A;  3TCZ A;  2M8I A;  2XP8 A;  1O6W A;  3MCB B;  3KAB A;  2XP4 A;  1WMV A;  2JXW A;  3FSB A;  1K9Q A;  2DWV A;  3ODK A;  2ZQU A;  2WAD A;  2DJY A;  5E64 A;  2XP6 A;  2JX8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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