1WR7A

Solution structure of the third ww domain of nedd4-2
Total Genus 4
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
4
sequence length
41
structure length
41
Chain Sequence
GSPGIQSFLPPGWEMRIAPNGRPFFIDHNTKTTTWEDPRLK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structures of the WW domains of Nedd4-2
rcsb
molecule tags Ligase
source organism Mus musculus
molecule keywords Nedd4-2
total genus 4
structure length 41
sequence length 41
ec nomenclature ec 2.3.2.26: HECT-type E3 ubiquitin transferase.
pdb deposition date 2004-10-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00397 WW WW domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.70.10 Mainly Beta Single Sheet Ubiquitin Ligase Nedd4; Chain: W; Ubiquitin Ligase Nedd4; Chain: W; 1wr7A01
3L4HA 2DK1A 2DJYA 2JV4A 2DK7A 2DWVA 3M85A 2BA1A 3WH0A 1WR7A 1K9QA 5CQ2A 2ZR6A 3KAHA 2YSFA 2ZAJA 3OOBA 1YW5A 2M8JA 2ZR4A 2ZQVA 2YSBA 3TCZA 4E5RA 2JXWA 4U86A 3ODKA 2JMFA 2XP5A 2XP6A 3KADA 3CNGA 2M3OW 2RE3A 1EG3A 2XPBA 2XP9A 4REXA 2KXQA 1ZCNA 3KAFA 2XP3A 3M7NA 1O6WA 4U84A 2MDIA 3KABA 4U85A 1TK7A 3TDBA 1I5HW 1EG4A 2ITKA 2M8IA 2XPAA 2YSHA 2DMVA 2ZQUA 2L4JA 2JX8A 3TC5A 2ZR5A 2XP7A 3KCEA 2LAJA 5AHTA 2XP4A 2F21A 1NMVA 3NTPA 1PINA 1JMQA 3KAGA 2ZQTA 4QIBA 3LE4A 3KAIA 2YSGA 1F8AB 1K9RA 2XP8A 2EZ5W 2E45A 2ZQSA 2YSIA 1WMVA 2Q5AA
chains in the Genus database with same CATH superfamily
3L4HA 2DK1A 2DJYA 3FSBA 2JV4A 2DK7A 2DWVA 3M85A 3FSCA 5E5WA 3MQHA 2BA1A 3PQHA 3WH0A 1WR7A 1K9QA 5CQ2A 2OWOA 2ZR6A 3KAHA 2YSFA 2ZAJA 3OOBA 1YW5A 2M8JA 2ZR4A 2ZQVA 5U47A 2YSBA 3TCZA 4E5RA 2JXWA 4U86A 1RP5A 3ODKA 2JMFA 2XP5A 2XP6A 3KADA 3CNGA 2M3OW 2RE3A 3MQGA 1EG3A 2XPBA 2XP9A 4REXA 2KXQA 1ZCNA 5E65A 4A0TA 3KAFA 2XP3A 3M7NA 1FLCA 1O6WA 2WAEA 4U84A 2MDIA 3KABA 4U85A 5E62A 2Y8NB 1TK7A 3TDBA 1I5HW 1EG4A 5E64A 2ITKA 2M8IA 2XPAA 2YSHA 2DMVA 4A0UA 1TR8A 2ZQUA 2L4JA 2JX8A 3TC5A 2ZR5A 2XP7A 3KCEA 2YAJB 2LAJA 5AHTA 2QRVA 3FS8A 2XP4A 2F21A 3MCBA 1NMVA 3MCBB 5E66A 3NTPA 1PINA 1JMQA 3KAGA 2ZQTA 4QIBA 3LE4A 3KAIA 2YSGA 1F8AB 4GLXA 1K9RA 3LKXA 3LKXB 2XP8A 2EZ5W 2E45A 2ZQSA 2YSIA 1WMVA 2Q5AA 2WADA
chains in the Genus database with same CATH topology
3L4HA 2DK1A 2DJYA 3FSBA 2JV4A 2DK7A 2DWVA 3M85A 3FSCA 5E5WA 3MQHA 2BA1A 3PQHA 3WH0A 1WR7A 1K9QA 5CQ2A 2OWOA 2ZR6A 3KAHA 2YSFA 2ZAJA 3OOBA 1YW5A 2M8JA 2ZR4A 2ZQVA 5U47A 2YSBA 3TCZA 4E5RA 2JXWA 4U86A 1RP5A 3ODKA 2JMFA 2XP5A 2XP6A 3KADA 3CNGA 2M3OW 2RE3A 3MQGA 1EG3A 2XPBA 2XP9A 4REXA 2KXQA 1ZCNA 5E65A 4A0TA 3KAFA 2XP3A 3M7NA 1FLCA 1O6WA 2WAEA 4U84A 2MDIA 3KABA 4U85A 5E62A 2Y8NB 1TK7A 3TDBA 1I5HW 1EG4A 5E64A 2ITKA 2M8IA 2XPAA 2YSHA 2DMVA 4A0UA 1TR8A 2ZQUA 2L4JA 2JX8A 3TC5A 2ZR5A 2XP7A 3KCEA 2YAJB 2LAJA 5AHTA 2QRVA 3FS8A 2XP4A 2F21A 3MCBA 1NMVA 3MCBB 5E66A 3NTPA 1PINA 1JMQA 3KAGA 2ZQTA 4QIBA 3LE4A 3KAIA 2YSGA 1F8AB 4GLXA 1K9RA 3LKXA 3LKXB 2XP8A 2EZ5W 2E45A 2ZQSA 2YSIA 1WMVA 2Q5AA 2WADA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3L4H A;  2DK1 A;  2DJY A;  2JV4 A;  2DK7 A;  2DWV A;  3M85 A;  2BA1 A;  3WH0 A;  1WR7 A;  1K9Q A;  5CQ2 A;  2ZR6 A;  3KAH A;  2YSF A;  2ZAJ A;  3OOB A;  1YW5 A;  2M8J A;  2ZR4 A;  2ZQV A;  2YSB A;  3TCZ A;  4E5R A;  2JXW A;  4U86 A;  3ODK A;  2JMF A;  2XP5 A;  2XP6 A;  3KAD A;  3CNG A;  2M3O W;  2RE3 A;  1EG3 A;  2XPB A;  2XP9 A;  4REX A;  2KXQ A;  1ZCN A;  3KAF A;  2XP3 A;  3M7N A;  1O6W A;  4U84 A;  2MDI A;  3KAB A;  4U85 A;  1TK7 A;  3TDB A;  1I5H W;  1EG4 A;  2ITK A;  2M8I A;  2XPA A;  2YSH A;  2DMV A;  2ZQU A;  2L4J A;  2JX8 A;  3TC5 A;  2ZR5 A;  2XP7 A;  3KCE A;  2LAJ A;  5AHT A;  2XP4 A;  2F21 A;  1NMV A;  3NTP A;  1PIN A;  1JMQ A;  3KAG A;  2ZQT A;  4QIB A;  3LE4 A;  3KAI A;  2YSG A;  1F8A B;  1K9R A;  2XP8 A;  2EZ5 W;  2E45 A;  2ZQS A;  2YSI A;  1WMV A;  2Q5A A; 
#chains in the Genus database with same CATH topology
 3L4H A;  2DK1 A;  2DJY A;  3FSB A;  2JV4 A;  2DK7 A;  2DWV A;  3M85 A;  3FSC A;  5E5W A;  3MQH A;  2BA1 A;  3PQH A;  3WH0 A;  1WR7 A;  1K9Q A;  5CQ2 A;  2OWO A;  2ZR6 A;  3KAH A;  2YSF A;  2ZAJ A;  3OOB A;  1YW5 A;  2M8J A;  2ZR4 A;  2ZQV A;  5U47 A;  2YSB A;  3TCZ A;  4E5R A;  2JXW A;  4U86 A;  1RP5 A;  3ODK A;  2JMF A;  2XP5 A;  2XP6 A;  3KAD A;  3CNG A;  2M3O W;  2RE3 A;  3MQG A;  1EG3 A;  2XPB A;  2XP9 A;  4REX A;  2KXQ A;  1ZCN A;  5E65 A;  4A0T A;  3KAF A;  2XP3 A;  3M7N A;  1FLC A;  1O6W A;  2WAE A;  4U84 A;  2MDI A;  3KAB A;  4U85 A;  5E62 A;  2Y8N B;  1TK7 A;  3TDB A;  1I5H W;  1EG4 A;  5E64 A;  2ITK A;  2M8I A;  2XPA A;  2YSH A;  2DMV A;  4A0U A;  1TR8 A;  2ZQU A;  2L4J A;  2JX8 A;  3TC5 A;  2ZR5 A;  2XP7 A;  3KCE A;  2YAJ B;  2LAJ A;  5AHT A;  2QRV A;  3FS8 A;  2XP4 A;  2F21 A;  3MCB A;  1NMV A;  3MCB B;  5E66 A;  3NTP A;  1PIN A;  1JMQ A;  3KAG A;  2ZQT A;  4QIB A;  3LE4 A;  3KAI A;  2YSG A;  1F8A B;  4GLX A;  1K9R A;  3LKX A;  3LKX B;  2XP8 A;  2EZ5 W;  2E45 A;  2ZQS A;  2YSI A;  1WMV A;  2Q5A A;  2WAD A; 
#chains in the Genus database with same CATH homology
 3L4H A;  2DK1 A;  2DJY A;  3FSB A;  2JV4 A;  2DK7 A;  2DWV A;  3M85 A;  3FSC A;  5E5W A;  3MQH A;  2BA1 A;  3PQH A;  3WH0 A;  1WR7 A;  1K9Q A;  5CQ2 A;  2OWO A;  2ZR6 A;  3KAH A;  2YSF A;  2ZAJ A;  3OOB A;  1YW5 A;  2M8J A;  2ZR4 A;  2ZQV A;  5U47 A;  2YSB A;  3TCZ A;  4E5R A;  2JXW A;  4U86 A;  1RP5 A;  3ODK A;  2JMF A;  2XP5 A;  2XP6 A;  3KAD A;  3CNG A;  2M3O W;  2RE3 A;  3MQG A;  1EG3 A;  2XPB A;  2XP9 A;  4REX A;  2KXQ A;  1ZCN A;  5E65 A;  4A0T A;  3KAF A;  2XP3 A;  3M7N A;  1FLC A;  1O6W A;  2WAE A;  4U84 A;  2MDI A;  3KAB A;  4U85 A;  5E62 A;  2Y8N B;  1TK7 A;  3TDB A;  1I5H W;  1EG4 A;  5E64 A;  2ITK A;  2M8I A;  2XPA A;  2YSH A;  2DMV A;  4A0U A;  1TR8 A;  2ZQU A;  2L4J A;  2JX8 A;  3TC5 A;  2ZR5 A;  2XP7 A;  3KCE A;  2YAJ B;  2LAJ A;  5AHT A;  2QRV A;  3FS8 A;  2XP4 A;  2F21 A;  3MCB A;  1NMV A;  3MCB B;  5E66 A;  3NTP A;  1PIN A;  1JMQ A;  3KAG A;  2ZQT A;  4QIB A;  3LE4 A;  3KAI A;  2YSG A;  1F8A B;  4GLX A;  1K9R A;  3LKX A;  3LKX B;  2XP8 A;  2EZ5 W;  2E45 A;  2ZQS A;  2YSI A;  1WMV A;  2Q5A A;  2WAD A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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