1JMQA

Yap65 (l30k mutant) ww domain in complex with gtppppytvg peptide
Total Genus 2
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
2
sequence length
46
structure length
46
Chain Sequence
FEIPDDVPLPAGWEMAKTSSGQRYFKNHIDQTTTWQDPRKAMLSQM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structures of the YAP65 WW domain and the variant L30 K in complex with the peptides GTPPPPYTVG, N-(n-octyl)-GPPPY and PLPPY and the application of peptide libraries reveal a minimal binding epitope.
pubmed doi rcsb
molecule tags Structural protein
source organism Homo sapiens
molecule keywords 65 KDA YES-ASSOCIATED PROTEIN
total genus 2
structure length 46
sequence length 46
ec nomenclature
pdb deposition date 2001-07-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00397 WW WW domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.70.10 Mainly Beta Single Sheet Ubiquitin Ligase Nedd4; Chain: W; Ubiquitin Ligase Nedd4; Chain: W; 1jmqA00
1K9RA 2ZQTA 2RE3A 1EG4A 2Q5AA 2E45A 1F8AB 2ZAJA 2XP5A 2L4JA 2XP7A 2YSHA 2YSBA 1EG3A 1YW5A 2M8IA 1WR7A 2YSIA 4U86A 2ZR5A 2ITKA 2ZQVA 2BA1A 2XPBA 2YSFA 2MDIA 3WH0A 3LE4A 2DWVA 2JXWA 4U85A 2KXQA 2ZQUA 1TK7A 2XP3A 3CNGA 1PINA 3TDBA 3NTPA 2F21A 5CQ2A 2DK1A 2XP6A 2JV4A 3KCEA 3M7NA 3OOBA 4REXA 2M3OW 1WMVA 2XPAA 3KAGA 2ZQSA 2DJYA 3KAIA 5AHTA 1O6WA 3M85A 2LAJA 3KABA 1ZCNA 3TCZA 2JMFA 4QIBA 3KAFA 2EZ5W 2JX8A 2M8JA 3KADA 2XP4A 1JMQA 1I5HW 3L4HA 2ZR6A 4E5RA 2DMVA 3TC5A 1NMVA 4U84A 3KAHA 1K9QA 2XP8A 2DK7A 2ZR4A 2YSGA 2XP9A 3ODKA
chains in the Genus database with same CATH superfamily
2QRVA 3LKXA 1K9RA 2ZQTA 2RE3A 1EG4A 2Q5AA 2Y8NB 2E45A 1F8AB 2ZAJA 2XP5A 4GLXA 2L4JA 2XP7A 2YSHA 2YSBA 3FS8A 1EG3A 1YW5A 3PQHA 2YAJB 3LKXB 2M8IA 1WR7A 2YSIA 4U86A 2WAEA 2ZR5A 2WADA 2ITKA 2ZQVA 5U47A 2BA1A 2XPBA 2YSFA 2MDIA 3WH0A 3LE4A 2DWVA 2JXWA 4U85A 5E65A 2KXQA 2ZQUA 1TK7A 3MQGA 2XP3A 3CNGA 1PINA 3TDBA 3NTPA 2F21A 3MQHA 5CQ2A 2DK1A 5E62A 2XP6A 2JV4A 3KCEA 4A0TA 1TR8A 3M7NA 3OOBA 4REXA 2OWOA 3MCBB 5E64A 2M3OW 1WMVA 3MCBA 2XPAA 4A0UA 3KAGA 2ZQSA 2DJYA 3KAIA 1FLCA 5AHTA 1O6WA 3M85A 5E5WA 3FSCA 2LAJA 3FSBA 3KABA 1ZCNA 5E66A 3TCZA 2JMFA 4QIBA 3KAFA 2EZ5W 2JX8A 2M8JA 3KADA 2XP4A 1JMQA 1I5HW 3L4HA 2ZR6A 4E5RA 2DMVA 3TC5A 1NMVA 4U84A 3KAHA 1K9QA 2XP8A 2DK7A 2ZR4A 2YSGA 1RP5A 2XP9A 3ODKA
chains in the Genus database with same CATH topology
2QRVA 3LKXA 1K9RA 2ZQTA 2RE3A 1EG4A 2Q5AA 2Y8NB 2E45A 1F8AB 2ZAJA 2XP5A 4GLXA 2L4JA 2XP7A 2YSHA 2YSBA 3FS8A 1EG3A 1YW5A 3PQHA 2YAJB 3LKXB 2M8IA 1WR7A 2YSIA 4U86A 2WAEA 2ZR5A 2WADA 2ITKA 2ZQVA 5U47A 2BA1A 2XPBA 2YSFA 2MDIA 3WH0A 3LE4A 2DWVA 2JXWA 4U85A 5E65A 2KXQA 2ZQUA 1TK7A 3MQGA 2XP3A 3CNGA 1PINA 3TDBA 3NTPA 2F21A 3MQHA 5CQ2A 2DK1A 5E62A 2XP6A 2JV4A 3KCEA 4A0TA 1TR8A 3M7NA 3OOBA 4REXA 2OWOA 3MCBB 5E64A 2M3OW 1WMVA 3MCBA 2XPAA 4A0UA 3KAGA 2ZQSA 2DJYA 3KAIA 1FLCA 5AHTA 1O6WA 3M85A 5E5WA 3FSCA 2LAJA 3FSBA 3KABA 1ZCNA 5E66A 3TCZA 2JMFA 4QIBA 3KAFA 2EZ5W 2JX8A 2M8JA 3KADA 2XP4A 1JMQA 1I5HW 3L4HA 2ZR6A 4E5RA 2DMVA 3TC5A 1NMVA 4U84A 3KAHA 1K9QA 2XP8A 2DK7A 2ZR4A 2YSGA 1RP5A 2XP9A 3ODKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1K9R A;  2ZQT A;  2RE3 A;  1EG4 A;  2Q5A A;  2E45 A;  1F8A B;  2ZAJ A;  2XP5 A;  2L4J A;  2XP7 A;  2YSH A;  2YSB A;  1EG3 A;  1YW5 A;  2M8I A;  1WR7 A;  2YSI A;  4U86 A;  2ZR5 A;  2ITK A;  2ZQV A;  2BA1 A;  2XPB A;  2YSF A;  2MDI A;  3WH0 A;  3LE4 A;  2DWV A;  2JXW A;  4U85 A;  2KXQ A;  2ZQU A;  1TK7 A;  2XP3 A;  3CNG A;  1PIN A;  3TDB A;  3NTP A;  2F21 A;  5CQ2 A;  2DK1 A;  2XP6 A;  2JV4 A;  3KCE A;  3M7N A;  3OOB A;  4REX A;  2M3O W;  1WMV A;  2XPA A;  3KAG A;  2ZQS A;  2DJY A;  3KAI A;  5AHT A;  1O6W A;  3M85 A;  2LAJ A;  3KAB A;  1ZCN A;  3TCZ A;  2JMF A;  4QIB A;  3KAF A;  2EZ5 W;  2JX8 A;  2M8J A;  3KAD A;  2XP4 A;  1JMQ A;  1I5H W;  3L4H A;  2ZR6 A;  4E5R A;  2DMV A;  3TC5 A;  1NMV A;  4U84 A;  3KAH A;  1K9Q A;  2XP8 A;  2DK7 A;  2ZR4 A;  2YSG A;  2XP9 A;  3ODK A; 
#chains in the Genus database with same CATH topology
 2QRV A;  3LKX A;  1K9R A;  2ZQT A;  2RE3 A;  1EG4 A;  2Q5A A;  2Y8N B;  2E45 A;  1F8A B;  2ZAJ A;  2XP5 A;  4GLX A;  2L4J A;  2XP7 A;  2YSH A;  2YSB A;  3FS8 A;  1EG3 A;  1YW5 A;  3PQH A;  2YAJ B;  3LKX B;  2M8I A;  1WR7 A;  2YSI A;  4U86 A;  2WAE A;  2ZR5 A;  2WAD A;  2ITK A;  2ZQV A;  5U47 A;  2BA1 A;  2XPB A;  2YSF A;  2MDI A;  3WH0 A;  3LE4 A;  2DWV A;  2JXW A;  4U85 A;  5E65 A;  2KXQ A;  2ZQU A;  1TK7 A;  3MQG A;  2XP3 A;  3CNG A;  1PIN A;  3TDB A;  3NTP A;  2F21 A;  3MQH A;  5CQ2 A;  2DK1 A;  5E62 A;  2XP6 A;  2JV4 A;  3KCE A;  4A0T A;  1TR8 A;  3M7N A;  3OOB A;  4REX A;  2OWO A;  3MCB B;  5E64 A;  2M3O W;  1WMV A;  3MCB A;  2XPA A;  4A0U A;  3KAG A;  2ZQS A;  2DJY A;  3KAI A;  1FLC A;  5AHT A;  1O6W A;  3M85 A;  5E5W A;  3FSC A;  2LAJ A;  3FSB A;  3KAB A;  1ZCN A;  5E66 A;  3TCZ A;  2JMF A;  4QIB A;  3KAF A;  2EZ5 W;  2JX8 A;  2M8J A;  3KAD A;  2XP4 A;  1JMQ A;  1I5H W;  3L4H A;  2ZR6 A;  4E5R A;  2DMV A;  3TC5 A;  1NMV A;  4U84 A;  3KAH A;  1K9Q A;  2XP8 A;  2DK7 A;  2ZR4 A;  2YSG A;  1RP5 A;  2XP9 A;  3ODK A; 
#chains in the Genus database with same CATH homology
 2QRV A;  3LKX A;  1K9R A;  2ZQT A;  2RE3 A;  1EG4 A;  2Q5A A;  2Y8N B;  2E45 A;  1F8A B;  2ZAJ A;  2XP5 A;  4GLX A;  2L4J A;  2XP7 A;  2YSH A;  2YSB A;  3FS8 A;  1EG3 A;  1YW5 A;  3PQH A;  2YAJ B;  3LKX B;  2M8I A;  1WR7 A;  2YSI A;  4U86 A;  2WAE A;  2ZR5 A;  2WAD A;  2ITK A;  2ZQV A;  5U47 A;  2BA1 A;  2XPB A;  2YSF A;  2MDI A;  3WH0 A;  3LE4 A;  2DWV A;  2JXW A;  4U85 A;  5E65 A;  2KXQ A;  2ZQU A;  1TK7 A;  3MQG A;  2XP3 A;  3CNG A;  1PIN A;  3TDB A;  3NTP A;  2F21 A;  3MQH A;  5CQ2 A;  2DK1 A;  5E62 A;  2XP6 A;  2JV4 A;  3KCE A;  4A0T A;  1TR8 A;  3M7N A;  3OOB A;  4REX A;  2OWO A;  3MCB B;  5E64 A;  2M3O W;  1WMV A;  3MCB A;  2XPA A;  4A0U A;  3KAG A;  2ZQS A;  2DJY A;  3KAI A;  1FLC A;  5AHT A;  1O6W A;  3M85 A;  5E5W A;  3FSC A;  2LAJ A;  3FSB A;  3KAB A;  1ZCN A;  5E66 A;  3TCZ A;  2JMF A;  4QIB A;  3KAF A;  2EZ5 W;  2JX8 A;  2M8J A;  3KAD A;  2XP4 A;  1JMQ A;  1I5H W;  3L4H A;  2ZR6 A;  4E5R A;  2DMV A;  3TC5 A;  1NMV A;  4U84 A;  3KAH A;  1K9Q A;  2XP8 A;  2DK7 A;  2ZR4 A;  2YSG A;  1RP5 A;  2XP9 A;  3ODK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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