1JMQA

Yap65 (l30k mutant) ww domain in complex with gtppppytvg peptide
Total Genus 2
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
2
sequence length
46
structure length
46
Chain Sequence
FEIPDDVPLPAGWEMAKTSSGQRYFKNHIDQTTTWQDPRKAMLSQM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structures of the YAP65 WW domain and the variant L30 K in complex with the peptides GTPPPPYTVG, N-(n-octyl)-GPPPY and PLPPY and the application of peptide libraries reveal a minimal binding epitope.
pubmed doi rcsb
molecule tags Structural protein
source organism Homo sapiens
molecule keywords 65 KDA YES-ASSOCIATED PROTEIN
total genus 2
structure length 46
sequence length 46
ec nomenclature
pdb deposition date 2001-07-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00397 WW WW domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.70.10 Mainly Beta Single Sheet Ubiquitin Ligase Nedd4; Chain: W; Ubiquitin Ligase Nedd4; Chain: W; 1jmqA00
2YSGA 3WH0A 4E5RA 5CQ2A 3KAFA 2L4JA 3M7NA 2YSIA 3TDBA 3KADA 3NTPA 2DK7A 2F21A 3TC5A 1F8AB 2XP6A 2ZAJA 1WMVA 2ZR5A 1K9QA 1PINA 1YW5A 2M8IA 3M85A 4U86A 4U85A 3L4HA 2XP4A 3KAIA 2ZQSA 3KABA 2ZQVA 2ZR4A 2Q5AA 4QIBA 2M8JA 2ZQTA 2RE3A 3TCZA 3ODKA 2EZ5W 4U84A 2XP8A 2JX8A 1K9RA 2XP9A 2DMVA 2XP7A 2KXQA 4REXA 2DK1A 1EG3A 2DWVA 2ITKA 1JMQA 5AHTA 3OOBA 1EG4A 1NMVA 1ZCNA 2XPAA 2YSHA 2LAJA 2XPBA 2ZQUA 3KCEA 2DJYA 1I5HW 2XP5A 2ZR6A 2YSBA 2YSFA 2JMFA 3KAGA 2E45A 3CNGA 3LE4A 1O6WA 2JV4A 2JXWA 2XP3A 3KAHA 2M3OW 2BA1A 2MDIA 1WR7A 1TK7A
chains in the Genus database with same CATH superfamily
1FLCA 2YSGA 3FSCA 5E64A 3WH0A 4E5RA 3MQHA 5CQ2A 3KAFA 2L4JA 3M7NA 2YSIA 3TDBA 3KADA 3NTPA 2DK7A 2F21A 3TC5A 1F8AB 5E66A 2WADA 2XP6A 3MCBB 2ZAJA 1WMVA 2ZR5A 1K9QA 1PINA 3FS8A 1YW5A 2M8IA 1RP5A 3M85A 4U86A 4U85A 3L4HA 2XP4A 3KAIA 2ZQSA 3FSBA 3KABA 2ZQVA 2ZR4A 2Q5AA 4QIBA 2M8JA 2ZQTA 2RE3A 3TCZA 3PQHA 3ODKA 2EZ5W 4U84A 2XP8A 2JX8A 1K9RA 2XP9A 2DMVA 2XP7A 5E62A 2KXQA 4REXA 2DK1A 3MQGA 1EG3A 2DWVA 2ITKA 2QRVA 1JMQA 5AHTA 3OOBA 1EG4A 1NMVA 3LKXA 1ZCNA 2XPAA 5E5WA 2YSHA 4A0TA 5E65A 2LAJA 2XPBA 2ZQUA 3KCEA 2DJYA 1TR8A 2Y8NB 2OWOA 1I5HW 2XP5A 2ZR6A 2YSBA 2YAJB 2YSFA 2JMFA 5U47A 4GLXA 3KAGA 2E45A 3MCBA 3CNGA 3LE4A 1O6WA 2JV4A 2JXWA 2XP3A 3KAHA 2M3OW 2BA1A 2MDIA 3LKXB 1WR7A 1TK7A 4A0UA 2WAEA
chains in the Genus database with same CATH topology
1FLCA 2YSGA 3FSCA 5E64A 3WH0A 4E5RA 3MQHA 5CQ2A 3KAFA 2L4JA 3M7NA 2YSIA 3TDBA 3KADA 3NTPA 2DK7A 2F21A 3TC5A 1F8AB 5E66A 2WADA 2XP6A 3MCBB 2ZAJA 1WMVA 2ZR5A 1K9QA 1PINA 3FS8A 1YW5A 2M8IA 1RP5A 3M85A 4U86A 4U85A 3L4HA 2XP4A 3KAIA 2ZQSA 3FSBA 3KABA 2ZQVA 2ZR4A 2Q5AA 4QIBA 2M8JA 2ZQTA 2RE3A 3TCZA 3PQHA 3ODKA 2EZ5W 4U84A 2XP8A 2JX8A 1K9RA 2XP9A 2DMVA 2XP7A 5E62A 2KXQA 4REXA 2DK1A 3MQGA 1EG3A 2DWVA 2ITKA 2QRVA 1JMQA 5AHTA 3OOBA 1EG4A 1NMVA 3LKXA 1ZCNA 2XPAA 5E5WA 2YSHA 4A0TA 5E65A 2LAJA 2XPBA 2ZQUA 3KCEA 2DJYA 1TR8A 2Y8NB 2OWOA 1I5HW 2XP5A 2ZR6A 2YSBA 2YAJB 2YSFA 2JMFA 5U47A 4GLXA 3KAGA 2E45A 3MCBA 3CNGA 3LE4A 1O6WA 2JV4A 2JXWA 2XP3A 3KAHA 2M3OW 2BA1A 2MDIA 3LKXB 1WR7A 1TK7A 4A0UA 2WAEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2YSG A;  3WH0 A;  4E5R A;  5CQ2 A;  3KAF A;  2L4J A;  3M7N A;  2YSI A;  3TDB A;  3KAD A;  3NTP A;  2DK7 A;  2F21 A;  3TC5 A;  1F8A B;  2XP6 A;  2ZAJ A;  1WMV A;  2ZR5 A;  1K9Q A;  1PIN A;  1YW5 A;  2M8I A;  3M85 A;  4U86 A;  4U85 A;  3L4H A;  2XP4 A;  3KAI A;  2ZQS A;  3KAB A;  2ZQV A;  2ZR4 A;  2Q5A A;  4QIB A;  2M8J A;  2ZQT A;  2RE3 A;  3TCZ A;  3ODK A;  2EZ5 W;  4U84 A;  2XP8 A;  2JX8 A;  1K9R A;  2XP9 A;  2DMV A;  2XP7 A;  2KXQ A;  4REX A;  2DK1 A;  1EG3 A;  2DWV A;  2ITK A;  1JMQ A;  5AHT A;  3OOB A;  1EG4 A;  1NMV A;  1ZCN A;  2XPA A;  2YSH A;  2LAJ A;  2XPB A;  2ZQU A;  3KCE A;  2DJY A;  1I5H W;  2XP5 A;  2ZR6 A;  2YSB A;  2YSF A;  2JMF A;  3KAG A;  2E45 A;  3CNG A;  3LE4 A;  1O6W A;  2JV4 A;  2JXW A;  2XP3 A;  3KAH A;  2M3O W;  2BA1 A;  2MDI A;  1WR7 A;  1TK7 A; 
#chains in the Genus database with same CATH topology
 1FLC A;  2YSG A;  3FSC A;  5E64 A;  3WH0 A;  4E5R A;  3MQH A;  5CQ2 A;  3KAF A;  2L4J A;  3M7N A;  2YSI A;  3TDB A;  3KAD A;  3NTP A;  2DK7 A;  2F21 A;  3TC5 A;  1F8A B;  5E66 A;  2WAD A;  2XP6 A;  3MCB B;  2ZAJ A;  1WMV A;  2ZR5 A;  1K9Q A;  1PIN A;  3FS8 A;  1YW5 A;  2M8I A;  1RP5 A;  3M85 A;  4U86 A;  4U85 A;  3L4H A;  2XP4 A;  3KAI A;  2ZQS A;  3FSB A;  3KAB A;  2ZQV A;  2ZR4 A;  2Q5A A;  4QIB A;  2M8J A;  2ZQT A;  2RE3 A;  3TCZ A;  3PQH A;  3ODK A;  2EZ5 W;  4U84 A;  2XP8 A;  2JX8 A;  1K9R A;  2XP9 A;  2DMV A;  2XP7 A;  5E62 A;  2KXQ A;  4REX A;  2DK1 A;  3MQG A;  1EG3 A;  2DWV A;  2ITK A;  2QRV A;  1JMQ A;  5AHT A;  3OOB A;  1EG4 A;  1NMV A;  3LKX A;  1ZCN A;  2XPA A;  5E5W A;  2YSH A;  4A0T A;  5E65 A;  2LAJ A;  2XPB A;  2ZQU A;  3KCE A;  2DJY A;  1TR8 A;  2Y8N B;  2OWO A;  1I5H W;  2XP5 A;  2ZR6 A;  2YSB A;  2YAJ B;  2YSF A;  2JMF A;  5U47 A;  4GLX A;  3KAG A;  2E45 A;  3MCB A;  3CNG A;  3LE4 A;  1O6W A;  2JV4 A;  2JXW A;  2XP3 A;  3KAH A;  2M3O W;  2BA1 A;  2MDI A;  3LKX B;  1WR7 A;  1TK7 A;  4A0U A;  2WAE A; 
#chains in the Genus database with same CATH homology
 1FLC A;  2YSG A;  3FSC A;  5E64 A;  3WH0 A;  4E5R A;  3MQH A;  5CQ2 A;  3KAF A;  2L4J A;  3M7N A;  2YSI A;  3TDB A;  3KAD A;  3NTP A;  2DK7 A;  2F21 A;  3TC5 A;  1F8A B;  5E66 A;  2WAD A;  2XP6 A;  3MCB B;  2ZAJ A;  1WMV A;  2ZR5 A;  1K9Q A;  1PIN A;  3FS8 A;  1YW5 A;  2M8I A;  1RP5 A;  3M85 A;  4U86 A;  4U85 A;  3L4H A;  2XP4 A;  3KAI A;  2ZQS A;  3FSB A;  3KAB A;  2ZQV A;  2ZR4 A;  2Q5A A;  4QIB A;  2M8J A;  2ZQT A;  2RE3 A;  3TCZ A;  3PQH A;  3ODK A;  2EZ5 W;  4U84 A;  2XP8 A;  2JX8 A;  1K9R A;  2XP9 A;  2DMV A;  2XP7 A;  5E62 A;  2KXQ A;  4REX A;  2DK1 A;  3MQG A;  1EG3 A;  2DWV A;  2ITK A;  2QRV A;  1JMQ A;  5AHT A;  3OOB A;  1EG4 A;  1NMV A;  3LKX A;  1ZCN A;  2XPA A;  5E5W A;  2YSH A;  4A0T A;  5E65 A;  2LAJ A;  2XPB A;  2ZQU A;  3KCE A;  2DJY A;  1TR8 A;  2Y8N B;  2OWO A;  1I5H W;  2XP5 A;  2ZR6 A;  2YSB A;  2YAJ B;  2YSF A;  2JMF A;  5U47 A;  4GLX A;  3KAG A;  2E45 A;  3MCB A;  3CNG A;  3LE4 A;  1O6W A;  2JV4 A;  2JXW A;  2XP3 A;  3KAH A;  2M3O W;  2BA1 A;  2MDI A;  3LKX B;  1WR7 A;  1TK7 A;  4A0U A;  2WAE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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