1K9QA

Yap65 ww domain complexed to n-(n-octyl)-gpppy-nh2
Total Genus 4
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
4
sequence length
40
structure length
40
Chain Sequence
FEIPDDVPLPAGWEMAKTSSGQRYFLNHIDQTTTWQDPRK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structures of the YAP65 WW domain and the variant L30 K in complex with the peptides GTPPPPYTVG, N-(n-octyl)-GPPPY and PLPPY and the application of peptide libraries reveal a minimal binding epitope.
pubmed doi rcsb
molecule tags Structural protein
molecule keywords 65 kDa Yes-associated protein
total genus 4
structure length 40
sequence length 40
ec nomenclature
pdb deposition date 2001-10-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00397 WW WW domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.70.10 Mainly Beta Single Sheet Ubiquitin Ligase Nedd4; Chain: W; Ubiquitin Ligase Nedd4; Chain: W; 1k9qA00
2XP8A 3M7NA 3CNGA 2E45A 1F8AB 2XP3A 2YSHA 2KXQA 4E5RA 4U85A 1O6WA 2DJYA 3KAFA 2YSGA 2XPAA 2XP7A 2DWVA 2XP4A 3KAIA 2ZQTA 3TC5A 2JMFA 3KAHA 2JV4A 3WH0A 4U84A 3OOBA 1WMVA 1WR7A 2DMVA 3TDBA 1EG4A 2M3OW 2L4JA 2ZAJA 2ZR4A 2ZR6A 4REXA 2XP5A 2M8IA 3KAGA 4QIBA 2YSFA 1ZCNA 3KABA 3KADA 3NTPA 3TCZA 2BA1A 2ZQSA 2JX8A 2ZR5A 1K9RA 2ZQVA 2LAJA 3LE4A 1I5HW 2Q5AA 1TK7A 2JXWA 3L4HA 3M85A 2ITKA 3KCEA 5AHTA 1NMVA 1JMQA 1K9QA 2YSIA 3ODKA 1PINA 1YW5A 2DK7A 1EG3A 2XP9A 2XPBA 2MDIA 2XP6A 5CQ2A 2RE3A 2ZQUA 2DK1A 4U86A 2EZ5W 2YSBA 2F21A 2M8JA
chains in the Genus database with same CATH superfamily
5E66A 1FLCA 2XP8A 3M7NA 3CNGA 2E45A 1F8AB 3MCBA 2XP3A 2YSHA 3PQHA 3LKXA 2KXQA 4E5RA 4U85A 1O6WA 3FS8A 5U47A 2DJYA 3KAFA 2YSGA 2XPAA 2XP7A 2DWVA 2YAJB 2XP4A 3KAIA 2ZQTA 3TC5A 2JMFA 3KAHA 2JV4A 3WH0A 4U84A 3OOBA 1WMVA 3MQGA 5E65A 2QRVA 2WADA 1WR7A 2DMVA 3TDBA 1EG4A 2M3OW 4GLXA 2L4JA 2ZAJA 2ZR4A 2ZR6A 4REXA 3MQHA 2WAEA 2XP5A 1RP5A 2M8IA 3KAGA 1TR8A 4QIBA 2YSFA 1ZCNA 3KABA 3KADA 2Y8NB 5E5WA 3NTPA 3TCZA 2BA1A 2ZQSA 2JX8A 2ZR5A 1K9RA 2ZQVA 2LAJA 3LE4A 1I5HW 3FSBA 2Q5AA 1TK7A 2JXWA 3L4HA 4A0TA 3M85A 2ITKA 3KCEA 5AHTA 1NMVA 1JMQA 1K9QA 2YSIA 3ODKA 3MCBB 1PINA 1YW5A 2DK7A 3LKXB 1EG3A 2XP9A 2XPBA 5E62A 4A0UA 2MDIA 2XP6A 5CQ2A 3FSCA 2RE3A 2ZQUA 2DK1A 4U86A 2EZ5W 5E64A 2YSBA 2F21A 2OWOA 2M8JA
chains in the Genus database with same CATH topology
5E66A 1FLCA 2XP8A 3M7NA 3CNGA 2E45A 1F8AB 3MCBA 2XP3A 2YSHA 3PQHA 3LKXA 2KXQA 4E5RA 4U85A 1O6WA 3FS8A 5U47A 2DJYA 3KAFA 2YSGA 2XPAA 2XP7A 2DWVA 2YAJB 2XP4A 3KAIA 2ZQTA 3TC5A 2JMFA 3KAHA 2JV4A 3WH0A 4U84A 3OOBA 1WMVA 3MQGA 5E65A 2QRVA 2WADA 1WR7A 2DMVA 3TDBA 1EG4A 2M3OW 4GLXA 2L4JA 2ZAJA 2ZR4A 2ZR6A 4REXA 3MQHA 2WAEA 2XP5A 1RP5A 2M8IA 3KAGA 1TR8A 4QIBA 2YSFA 1ZCNA 3KABA 3KADA 2Y8NB 5E5WA 3NTPA 3TCZA 2BA1A 2ZQSA 2JX8A 2ZR5A 1K9RA 2ZQVA 2LAJA 3LE4A 1I5HW 3FSBA 2Q5AA 1TK7A 2JXWA 3L4HA 4A0TA 3M85A 2ITKA 3KCEA 5AHTA 1NMVA 1JMQA 1K9QA 2YSIA 3ODKA 3MCBB 1PINA 1YW5A 2DK7A 3LKXB 1EG3A 2XP9A 2XPBA 5E62A 4A0UA 2MDIA 2XP6A 5CQ2A 3FSCA 2RE3A 2ZQUA 2DK1A 4U86A 2EZ5W 5E64A 2YSBA 2F21A 2OWOA 2M8JA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2XP8 A;  3M7N A;  3CNG A;  2E45 A;  1F8A B;  2XP3 A;  2YSH A;  2KXQ A;  4E5R A;  4U85 A;  1O6W A;  2DJY A;  3KAF A;  2YSG A;  2XPA A;  2XP7 A;  2DWV A;  2XP4 A;  3KAI A;  2ZQT A;  3TC5 A;  2JMF A;  3KAH A;  2JV4 A;  3WH0 A;  4U84 A;  3OOB A;  1WMV A;  1WR7 A;  2DMV A;  3TDB A;  1EG4 A;  2M3O W;  2L4J A;  2ZAJ A;  2ZR4 A;  2ZR6 A;  4REX A;  2XP5 A;  2M8I A;  3KAG A;  4QIB A;  2YSF A;  1ZCN A;  3KAB A;  3KAD A;  3NTP A;  3TCZ A;  2BA1 A;  2ZQS A;  2JX8 A;  2ZR5 A;  1K9R A;  2ZQV A;  2LAJ A;  3LE4 A;  1I5H W;  2Q5A A;  1TK7 A;  2JXW A;  3L4H A;  3M85 A;  2ITK A;  3KCE A;  5AHT A;  1NMV A;  1JMQ A;  1K9Q A;  2YSI A;  3ODK A;  1PIN A;  1YW5 A;  2DK7 A;  1EG3 A;  2XP9 A;  2XPB A;  2MDI A;  2XP6 A;  5CQ2 A;  2RE3 A;  2ZQU A;  2DK1 A;  4U86 A;  2EZ5 W;  2YSB A;  2F21 A;  2M8J A; 
#chains in the Genus database with same CATH topology
 5E66 A;  1FLC A;  2XP8 A;  3M7N A;  3CNG A;  2E45 A;  1F8A B;  3MCB A;  2XP3 A;  2YSH A;  3PQH A;  3LKX A;  2KXQ A;  4E5R A;  4U85 A;  1O6W A;  3FS8 A;  5U47 A;  2DJY A;  3KAF A;  2YSG A;  2XPA A;  2XP7 A;  2DWV A;  2YAJ B;  2XP4 A;  3KAI A;  2ZQT A;  3TC5 A;  2JMF A;  3KAH A;  2JV4 A;  3WH0 A;  4U84 A;  3OOB A;  1WMV A;  3MQG A;  5E65 A;  2QRV A;  2WAD A;  1WR7 A;  2DMV A;  3TDB A;  1EG4 A;  2M3O W;  4GLX A;  2L4J A;  2ZAJ A;  2ZR4 A;  2ZR6 A;  4REX A;  3MQH A;  2WAE A;  2XP5 A;  1RP5 A;  2M8I A;  3KAG A;  1TR8 A;  4QIB A;  2YSF A;  1ZCN A;  3KAB A;  3KAD A;  2Y8N B;  5E5W A;  3NTP A;  3TCZ A;  2BA1 A;  2ZQS A;  2JX8 A;  2ZR5 A;  1K9R A;  2ZQV A;  2LAJ A;  3LE4 A;  1I5H W;  3FSB A;  2Q5A A;  1TK7 A;  2JXW A;  3L4H A;  4A0T A;  3M85 A;  2ITK A;  3KCE A;  5AHT A;  1NMV A;  1JMQ A;  1K9Q A;  2YSI A;  3ODK A;  3MCB B;  1PIN A;  1YW5 A;  2DK7 A;  3LKX B;  1EG3 A;  2XP9 A;  2XPB A;  5E62 A;  4A0U A;  2MDI A;  2XP6 A;  5CQ2 A;  3FSC A;  2RE3 A;  2ZQU A;  2DK1 A;  4U86 A;  2EZ5 W;  5E64 A;  2YSB A;  2F21 A;  2OWO A;  2M8J A; 
#chains in the Genus database with same CATH homology
 5E66 A;  1FLC A;  2XP8 A;  3M7N A;  3CNG A;  2E45 A;  1F8A B;  3MCB A;  2XP3 A;  2YSH A;  3PQH A;  3LKX A;  2KXQ A;  4E5R A;  4U85 A;  1O6W A;  3FS8 A;  5U47 A;  2DJY A;  3KAF A;  2YSG A;  2XPA A;  2XP7 A;  2DWV A;  2YAJ B;  2XP4 A;  3KAI A;  2ZQT A;  3TC5 A;  2JMF A;  3KAH A;  2JV4 A;  3WH0 A;  4U84 A;  3OOB A;  1WMV A;  3MQG A;  5E65 A;  2QRV A;  2WAD A;  1WR7 A;  2DMV A;  3TDB A;  1EG4 A;  2M3O W;  4GLX A;  2L4J A;  2ZAJ A;  2ZR4 A;  2ZR6 A;  4REX A;  3MQH A;  2WAE A;  2XP5 A;  1RP5 A;  2M8I A;  3KAG A;  1TR8 A;  4QIB A;  2YSF A;  1ZCN A;  3KAB A;  3KAD A;  2Y8N B;  5E5W A;  3NTP A;  3TCZ A;  2BA1 A;  2ZQS A;  2JX8 A;  2ZR5 A;  1K9R A;  2ZQV A;  2LAJ A;  3LE4 A;  1I5H W;  3FSB A;  2Q5A A;  1TK7 A;  2JXW A;  3L4H A;  4A0T A;  3M85 A;  2ITK A;  3KCE A;  5AHT A;  1NMV A;  1JMQ A;  1K9Q A;  2YSI A;  3ODK A;  3MCB B;  1PIN A;  1YW5 A;  2DK7 A;  3LKX B;  1EG3 A;  2XP9 A;  2XPB A;  5E62 A;  4A0U A;  2MDI A;  2XP6 A;  5CQ2 A;  3FSC A;  2RE3 A;  2ZQU A;  2DK1 A;  4U86 A;  2EZ5 W;  5E64 A;  2YSB A;  2F21 A;  2OWO A;  2M8J A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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