1WR7A

Solution structure of the third ww domain of nedd4-2
Total Genus 4
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
4
sequence length
41
structure length
41
Chain Sequence
GSPGIQSFLPPGWEMRIAPNGRPFFIDHNTKTTTWEDPRLK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structures of the WW domains of Nedd4-2
rcsb
molecule tags Ligase
source organism Mus musculus
molecule keywords Nedd4-2
total genus 4
structure length 41
sequence length 41
ec nomenclature ec 2.3.2.26: HECT-type E3 ubiquitin transferase.
pdb deposition date 2004-10-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00397 WW WW domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.70.10 Mainly Beta Single Sheet Ubiquitin Ligase Nedd4; Chain: W; Ubiquitin Ligase Nedd4; Chain: W; 1wr7A01
3KADA 2RE3A 2JX8A 3TC5A 2ZQUA 2M3OW 2MDIA 4E5RA 1K9QA 2XP4A 2YSHA 3LE4A 4REXA 2DK7A 2DMVA 2YSBA 2XP5A 5AHTA 1TK7A 3KAHA 2ZQSA 2ZAJA 3KABA 3OOBA 1NMVA 2XPBA 1I5HW 3M85A 2Q5AA 1WMVA 2ZR5A 2XPAA 3KAGA 4U84A 2DWVA 2XP8A 2ZR6A 2LAJA 2XP7A 3L4HA 2XP6A 2JMFA 3NTPA 2M8IA 3WH0A 2ZQVA 1ZCNA 2YSFA 1YW5A 1EG4A 4U86A 2M8JA 1F8AB 3ODKA 3KCEA 2DK1A 3CNGA 2L4JA 3KAFA 2ITKA 2YSIA 2DJYA 2BA1A 3KAIA 3TCZA 2F21A 2JXWA 2YSGA 2KXQA 1WR7A 2XP3A 1JMQA 2EZ5W 2XP9A 3TDBA 2ZR4A 2E45A 1EG3A 4QIBA 5CQ2A 1PINA 1O6WA 2ZQTA 2JV4A 4U85A 3M7NA 1K9RA
chains in the Genus database with same CATH superfamily
3MQGA 3KADA 2RE3A 2JX8A 3FS8A 3TC5A 2ZQUA 2M3OW 2MDIA 4E5RA 4A0TA 1K9QA 2XP4A 3MQHA 2YSHA 3LE4A 4REXA 4GLXA 2DK7A 2DMVA 2YSBA 2XP5A 5AHTA 1TR8A 1TK7A 1RP5A 3KAHA 3PQHA 2ZQSA 3FSBA 2ZAJA 3KABA 3OOBA 1NMVA 2XPBA 5E5WA 1I5HW 3M85A 2Q5AA 1WMVA 2ZR5A 2XPAA 3KAGA 4U84A 2DWVA 2XP8A 2ZR6A 3LKXB 2LAJA 2XP7A 3L4HA 3MCBB 2XP6A 2JMFA 3NTPA 2M8IA 2Y8NB 3WH0A 2QRVA 2ZQVA 1ZCNA 5U47A 2YSFA 1YW5A 1EG4A 4U86A 2M8JA 1F8AB 3ODKA 3KCEA 1FLCA 2YAJB 2DK1A 3CNGA 2OWOA 2WAEA 2L4JA 3KAFA 5E62A 2ITKA 2YSIA 2DJYA 2BA1A 3KAIA 3LKXA 5E66A 3TCZA 2F21A 3MCBA 2JXWA 2YSGA 2KXQA 1WR7A 2XP3A 1JMQA 2WADA 2EZ5W 2XP9A 5E65A 3TDBA 2ZR4A 2E45A 4A0UA 1EG3A 4QIBA 5CQ2A 1PINA 3FSCA 1O6WA 5E64A 2ZQTA 2JV4A 4U85A 3M7NA 1K9RA
chains in the Genus database with same CATH topology
3MQGA 3KADA 2RE3A 2JX8A 3FS8A 3TC5A 2ZQUA 2M3OW 2MDIA 4E5RA 4A0TA 1K9QA 2XP4A 3MQHA 2YSHA 3LE4A 4REXA 4GLXA 2DK7A 2DMVA 2YSBA 2XP5A 5AHTA 1TR8A 1TK7A 1RP5A 3KAHA 3PQHA 2ZQSA 3FSBA 2ZAJA 3KABA 3OOBA 1NMVA 2XPBA 5E5WA 1I5HW 3M85A 2Q5AA 1WMVA 2ZR5A 2XPAA 3KAGA 4U84A 2DWVA 2XP8A 2ZR6A 3LKXB 2LAJA 2XP7A 3L4HA 3MCBB 2XP6A 2JMFA 3NTPA 2M8IA 2Y8NB 3WH0A 2QRVA 2ZQVA 1ZCNA 5U47A 2YSFA 1YW5A 1EG4A 4U86A 2M8JA 1F8AB 3ODKA 3KCEA 1FLCA 2YAJB 2DK1A 3CNGA 2OWOA 2WAEA 2L4JA 3KAFA 5E62A 2ITKA 2YSIA 2DJYA 2BA1A 3KAIA 3LKXA 5E66A 3TCZA 2F21A 3MCBA 2JXWA 2YSGA 2KXQA 1WR7A 2XP3A 1JMQA 2WADA 2EZ5W 2XP9A 5E65A 3TDBA 2ZR4A 2E45A 4A0UA 1EG3A 4QIBA 5CQ2A 1PINA 3FSCA 1O6WA 5E64A 2ZQTA 2JV4A 4U85A 3M7NA 1K9RA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3KAD A;  2RE3 A;  2JX8 A;  3TC5 A;  2ZQU A;  2M3O W;  2MDI A;  4E5R A;  1K9Q A;  2XP4 A;  2YSH A;  3LE4 A;  4REX A;  2DK7 A;  2DMV A;  2YSB A;  2XP5 A;  5AHT A;  1TK7 A;  3KAH A;  2ZQS A;  2ZAJ A;  3KAB A;  3OOB A;  1NMV A;  2XPB A;  1I5H W;  3M85 A;  2Q5A A;  1WMV A;  2ZR5 A;  2XPA A;  3KAG A;  4U84 A;  2DWV A;  2XP8 A;  2ZR6 A;  2LAJ A;  2XP7 A;  3L4H A;  2XP6 A;  2JMF A;  3NTP A;  2M8I A;  3WH0 A;  2ZQV A;  1ZCN A;  2YSF A;  1YW5 A;  1EG4 A;  4U86 A;  2M8J A;  1F8A B;  3ODK A;  3KCE A;  2DK1 A;  3CNG A;  2L4J A;  3KAF A;  2ITK A;  2YSI A;  2DJY A;  2BA1 A;  3KAI A;  3TCZ A;  2F21 A;  2JXW A;  2YSG A;  2KXQ A;  1WR7 A;  2XP3 A;  1JMQ A;  2EZ5 W;  2XP9 A;  3TDB A;  2ZR4 A;  2E45 A;  1EG3 A;  4QIB A;  5CQ2 A;  1PIN A;  1O6W A;  2ZQT A;  2JV4 A;  4U85 A;  3M7N A;  1K9R A; 
#chains in the Genus database with same CATH topology
 3MQG A;  3KAD A;  2RE3 A;  2JX8 A;  3FS8 A;  3TC5 A;  2ZQU A;  2M3O W;  2MDI A;  4E5R A;  4A0T A;  1K9Q A;  2XP4 A;  3MQH A;  2YSH A;  3LE4 A;  4REX A;  4GLX A;  2DK7 A;  2DMV A;  2YSB A;  2XP5 A;  5AHT A;  1TR8 A;  1TK7 A;  1RP5 A;  3KAH A;  3PQH A;  2ZQS A;  3FSB A;  2ZAJ A;  3KAB A;  3OOB A;  1NMV A;  2XPB A;  5E5W A;  1I5H W;  3M85 A;  2Q5A A;  1WMV A;  2ZR5 A;  2XPA A;  3KAG A;  4U84 A;  2DWV A;  2XP8 A;  2ZR6 A;  3LKX B;  2LAJ A;  2XP7 A;  3L4H A;  3MCB B;  2XP6 A;  2JMF A;  3NTP A;  2M8I A;  2Y8N B;  3WH0 A;  2QRV A;  2ZQV A;  1ZCN A;  5U47 A;  2YSF A;  1YW5 A;  1EG4 A;  4U86 A;  2M8J A;  1F8A B;  3ODK A;  3KCE A;  1FLC A;  2YAJ B;  2DK1 A;  3CNG A;  2OWO A;  2WAE A;  2L4J A;  3KAF A;  5E62 A;  2ITK A;  2YSI A;  2DJY A;  2BA1 A;  3KAI A;  3LKX A;  5E66 A;  3TCZ A;  2F21 A;  3MCB A;  2JXW A;  2YSG A;  2KXQ A;  1WR7 A;  2XP3 A;  1JMQ A;  2WAD A;  2EZ5 W;  2XP9 A;  5E65 A;  3TDB A;  2ZR4 A;  2E45 A;  4A0U A;  1EG3 A;  4QIB A;  5CQ2 A;  1PIN A;  3FSC A;  1O6W A;  5E64 A;  2ZQT A;  2JV4 A;  4U85 A;  3M7N A;  1K9R A; 
#chains in the Genus database with same CATH homology
 3MQG A;  3KAD A;  2RE3 A;  2JX8 A;  3FS8 A;  3TC5 A;  2ZQU A;  2M3O W;  2MDI A;  4E5R A;  4A0T A;  1K9Q A;  2XP4 A;  3MQH A;  2YSH A;  3LE4 A;  4REX A;  4GLX A;  2DK7 A;  2DMV A;  2YSB A;  2XP5 A;  5AHT A;  1TR8 A;  1TK7 A;  1RP5 A;  3KAH A;  3PQH A;  2ZQS A;  3FSB A;  2ZAJ A;  3KAB A;  3OOB A;  1NMV A;  2XPB A;  5E5W A;  1I5H W;  3M85 A;  2Q5A A;  1WMV A;  2ZR5 A;  2XPA A;  3KAG A;  4U84 A;  2DWV A;  2XP8 A;  2ZR6 A;  3LKX B;  2LAJ A;  2XP7 A;  3L4H A;  3MCB B;  2XP6 A;  2JMF A;  3NTP A;  2M8I A;  2Y8N B;  3WH0 A;  2QRV A;  2ZQV A;  1ZCN A;  5U47 A;  2YSF A;  1YW5 A;  1EG4 A;  4U86 A;  2M8J A;  1F8A B;  3ODK A;  3KCE A;  1FLC A;  2YAJ B;  2DK1 A;  3CNG A;  2OWO A;  2WAE A;  2L4J A;  3KAF A;  5E62 A;  2ITK A;  2YSI A;  2DJY A;  2BA1 A;  3KAI A;  3LKX A;  5E66 A;  3TCZ A;  2F21 A;  3MCB A;  2JXW A;  2YSG A;  2KXQ A;  1WR7 A;  2XP3 A;  1JMQ A;  2WAD A;  2EZ5 W;  2XP9 A;  5E65 A;  3TDB A;  2ZR4 A;  2E45 A;  4A0U A;  1EG3 A;  4QIB A;  5CQ2 A;  1PIN A;  3FSC A;  1O6W A;  5E64 A;  2ZQT A;  2JV4 A;  4U85 A;  3M7N A;  1K9R A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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