2E45A

Solution structure of fe65 ww domain
Total Genus 2
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
2
sequence length
50
structure length
50
Chain Sequence
DSFWNPNAFETDSDLPAGWMRVQDTSGTYYWHIPTGTTQWEPPGRASPSQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structure of Fe65 WW domain
rcsb
molecule tags Protein binding
source organism Homo sapiens
molecule keywords Amyloid beta A4 precursor protein-binding family B member 1
total genus 2
structure length 50
sequence length 50
ec nomenclature
pdb deposition date 2006-12-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00397 WW WW domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.70.10 Mainly Beta Single Sheet Ubiquitin Ligase Nedd4; Chain: W; Ubiquitin Ligase Nedd4; Chain: W; 2e45A01
1YW5A 2XP4A 2DJYA 3KADA 2DMVA 2JXWA 1EG3A 3KAFA 2ZR6A 1K9QA 2ZQSA 3KABA 2F21A 2ITKA 2ZR4A 2MDIA 2LAJA 3TDBA 3ODKA 2M8JA 2DK1A 3L4HA 3M85A 4U86A 3OOBA 1O6WA 2YSBA 3WH0A 2XP5A 2DWVA 2XP9A 2XP7A 3TC5A 2E45A 3NTPA 3KAIA 4U85A 3KAGA 2XPBA 1PINA 1I5HW 3KAHA 1WMVA 1K9RA 1EG4A 2ZQVA 2DK7A 2YSFA 1ZCNA 1F8AB 2M3OW 3KCEA 2Q5AA 2ZAJA 3LE4A 2EZ5W 2XP3A 2RE3A 2ZQUA 2XP8A 2ZQTA 2BA1A 1WR7A 2JX8A 1TK7A 2JV4A 2ZR5A 1JMQA 2M8IA 5AHTA 2XP6A 2JMFA 3TCZA 2YSHA 4E5RA 1NMVA 4U84A 2XPAA 2KXQA 3M7NA 4QIBA 2L4JA 3CNGA 5CQ2A 2YSIA 2YSGA 4REXA
chains in the Genus database with same CATH superfamily
1YW5A 2XP4A 4GLXA 2DJYA 2Y8NB 3KADA 2DMVA 2OWOA 2QRVA 1TR8A 3PQHA 2JXWA 3MQHA 3FSBA 1EG3A 3KAFA 2ZR6A 1K9QA 5E64A 2ZQSA 3KABA 3LKXA 2F21A 2ITKA 2ZR4A 2MDIA 2LAJA 3TDBA 3MQGA 3ODKA 2M8JA 2DK1A 3L4HA 3LKXB 3M85A 4U86A 3OOBA 1O6WA 2YSBA 3WH0A 2XP5A 2DWVA 2XP9A 2XP7A 5E65A 3TC5A 4A0TA 2YAJB 2E45A 3NTPA 3KAIA 1RP5A 4U85A 3KAGA 2XPBA 1PINA 1I5HW 3KAHA 1WMVA 1K9RA 1EG4A 2ZQVA 2DK7A 2YSFA 1FLCA 1ZCNA 1F8AB 2M3OW 5E62A 3KCEA 2Q5AA 3FSCA 2ZAJA 3MCBA 3LE4A 2EZ5W 2XP3A 2RE3A 2WAEA 2ZQUA 5E5WA 2XP8A 2ZQTA 2BA1A 1WR7A 3MCBB 2JX8A 1TK7A 2JV4A 5U47A 2ZR5A 5E66A 1JMQA 2WADA 2M8IA 5AHTA 2XP6A 2JMFA 3TCZA 2YSHA 4E5RA 1NMVA 4U84A 2XPAA 3FS8A 2KXQA 3M7NA 4QIBA 2L4JA 3CNGA 5CQ2A 4A0UA 2YSIA 2YSGA 4REXA
chains in the Genus database with same CATH topology
1YW5A 2XP4A 4GLXA 2DJYA 2Y8NB 3KADA 2DMVA 2OWOA 2QRVA 1TR8A 3PQHA 2JXWA 3MQHA 3FSBA 1EG3A 3KAFA 2ZR6A 1K9QA 5E64A 2ZQSA 3KABA 3LKXA 2F21A 2ITKA 2ZR4A 2MDIA 2LAJA 3TDBA 3MQGA 3ODKA 2M8JA 2DK1A 3L4HA 3LKXB 3M85A 4U86A 3OOBA 1O6WA 2YSBA 3WH0A 2XP5A 2DWVA 2XP9A 2XP7A 5E65A 3TC5A 4A0TA 2YAJB 2E45A 3NTPA 3KAIA 1RP5A 4U85A 3KAGA 2XPBA 1PINA 1I5HW 3KAHA 1WMVA 1K9RA 1EG4A 2ZQVA 2DK7A 2YSFA 1FLCA 1ZCNA 1F8AB 2M3OW 5E62A 3KCEA 2Q5AA 3FSCA 2ZAJA 3MCBA 3LE4A 2EZ5W 2XP3A 2RE3A 2WAEA 2ZQUA 5E5WA 2XP8A 2ZQTA 2BA1A 1WR7A 3MCBB 2JX8A 1TK7A 2JV4A 5U47A 2ZR5A 5E66A 1JMQA 2WADA 2M8IA 5AHTA 2XP6A 2JMFA 3TCZA 2YSHA 4E5RA 1NMVA 4U84A 2XPAA 3FS8A 2KXQA 3M7NA 4QIBA 2L4JA 3CNGA 5CQ2A 4A0UA 2YSIA 2YSGA 4REXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1YW5 A;  2XP4 A;  2DJY A;  3KAD A;  2DMV A;  2JXW A;  1EG3 A;  3KAF A;  2ZR6 A;  1K9Q A;  2ZQS A;  3KAB A;  2F21 A;  2ITK A;  2ZR4 A;  2MDI A;  2LAJ A;  3TDB A;  3ODK A;  2M8J A;  2DK1 A;  3L4H A;  3M85 A;  4U86 A;  3OOB A;  1O6W A;  2YSB A;  3WH0 A;  2XP5 A;  2DWV A;  2XP9 A;  2XP7 A;  3TC5 A;  2E45 A;  3NTP A;  3KAI A;  4U85 A;  3KAG A;  2XPB A;  1PIN A;  1I5H W;  3KAH A;  1WMV A;  1K9R A;  1EG4 A;  2ZQV A;  2DK7 A;  2YSF A;  1ZCN A;  1F8A B;  2M3O W;  3KCE A;  2Q5A A;  2ZAJ A;  3LE4 A;  2EZ5 W;  2XP3 A;  2RE3 A;  2ZQU A;  2XP8 A;  2ZQT A;  2BA1 A;  1WR7 A;  2JX8 A;  1TK7 A;  2JV4 A;  2ZR5 A;  1JMQ A;  2M8I A;  5AHT A;  2XP6 A;  2JMF A;  3TCZ A;  2YSH A;  4E5R A;  1NMV A;  4U84 A;  2XPA A;  2KXQ A;  3M7N A;  4QIB A;  2L4J A;  3CNG A;  5CQ2 A;  2YSI A;  2YSG A;  4REX A; 
#chains in the Genus database with same CATH topology
 1YW5 A;  2XP4 A;  4GLX A;  2DJY A;  2Y8N B;  3KAD A;  2DMV A;  2OWO A;  2QRV A;  1TR8 A;  3PQH A;  2JXW A;  3MQH A;  3FSB A;  1EG3 A;  3KAF A;  2ZR6 A;  1K9Q A;  5E64 A;  2ZQS A;  3KAB A;  3LKX A;  2F21 A;  2ITK A;  2ZR4 A;  2MDI A;  2LAJ A;  3TDB A;  3MQG A;  3ODK A;  2M8J A;  2DK1 A;  3L4H A;  3LKX B;  3M85 A;  4U86 A;  3OOB A;  1O6W A;  2YSB A;  3WH0 A;  2XP5 A;  2DWV A;  2XP9 A;  2XP7 A;  5E65 A;  3TC5 A;  4A0T A;  2YAJ B;  2E45 A;  3NTP A;  3KAI A;  1RP5 A;  4U85 A;  3KAG A;  2XPB A;  1PIN A;  1I5H W;  3KAH A;  1WMV A;  1K9R A;  1EG4 A;  2ZQV A;  2DK7 A;  2YSF A;  1FLC A;  1ZCN A;  1F8A B;  2M3O W;  5E62 A;  3KCE A;  2Q5A A;  3FSC A;  2ZAJ A;  3MCB A;  3LE4 A;  2EZ5 W;  2XP3 A;  2RE3 A;  2WAE A;  2ZQU A;  5E5W A;  2XP8 A;  2ZQT A;  2BA1 A;  1WR7 A;  3MCB B;  2JX8 A;  1TK7 A;  2JV4 A;  5U47 A;  2ZR5 A;  5E66 A;  1JMQ A;  2WAD A;  2M8I A;  5AHT A;  2XP6 A;  2JMF A;  3TCZ A;  2YSH A;  4E5R A;  1NMV A;  4U84 A;  2XPA A;  3FS8 A;  2KXQ A;  3M7N A;  4QIB A;  2L4J A;  3CNG A;  5CQ2 A;  4A0U A;  2YSI A;  2YSG A;  4REX A; 
#chains in the Genus database with same CATH homology
 1YW5 A;  2XP4 A;  4GLX A;  2DJY A;  2Y8N B;  3KAD A;  2DMV A;  2OWO A;  2QRV A;  1TR8 A;  3PQH A;  2JXW A;  3MQH A;  3FSB A;  1EG3 A;  3KAF A;  2ZR6 A;  1K9Q A;  5E64 A;  2ZQS A;  3KAB A;  3LKX A;  2F21 A;  2ITK A;  2ZR4 A;  2MDI A;  2LAJ A;  3TDB A;  3MQG A;  3ODK A;  2M8J A;  2DK1 A;  3L4H A;  3LKX B;  3M85 A;  4U86 A;  3OOB A;  1O6W A;  2YSB A;  3WH0 A;  2XP5 A;  2DWV A;  2XP9 A;  2XP7 A;  5E65 A;  3TC5 A;  4A0T A;  2YAJ B;  2E45 A;  3NTP A;  3KAI A;  1RP5 A;  4U85 A;  3KAG A;  2XPB A;  1PIN A;  1I5H W;  3KAH A;  1WMV A;  1K9R A;  1EG4 A;  2ZQV A;  2DK7 A;  2YSF A;  1FLC A;  1ZCN A;  1F8A B;  2M3O W;  5E62 A;  3KCE A;  2Q5A A;  3FSC A;  2ZAJ A;  3MCB A;  3LE4 A;  2EZ5 W;  2XP3 A;  2RE3 A;  2WAE A;  2ZQU A;  5E5W A;  2XP8 A;  2ZQT A;  2BA1 A;  1WR7 A;  3MCB B;  2JX8 A;  1TK7 A;  2JV4 A;  5U47 A;  2ZR5 A;  5E66 A;  1JMQ A;  2WAD A;  2M8I A;  5AHT A;  2XP6 A;  2JMF A;  3TCZ A;  2YSH A;  4E5R A;  1NMV A;  4U84 A;  2XPA A;  3FS8 A;  2KXQ A;  3M7N A;  4QIB A;  2L4J A;  3CNG A;  5CQ2 A;  4A0U A;  2YSI A;  2YSG A;  4REX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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