2E45A

Solution structure of fe65 ww domain
Total Genus 2
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
2
sequence length
50
structure length
50
Chain Sequence
DSFWNPNAFETDSDLPAGWMRVQDTSGTYYWHIPTGTTQWEPPGRASPSQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Protein binding
source organism Homo sapiens
publication title Solution structure of Fe65 WW domain
rcsb
molecule keywords Amyloid beta A4 precursor protein-binding family B member 1
total genus 2
structure length 50
sequence length 50
ec nomenclature
pdb deposition date 2006-12-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00397 WW WW domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.70.10 Mainly Beta Single Sheet Ubiquitin Ligase Nedd4; Chain: W; Ubiquitin Ligase Nedd4; Chain: W; 2e45A01
2EZ5W 2M8IA 2DMVA 4U85A 3LE4A 2XP8A 3NTPA 4U84A 3WH0A 2YSGA 3TDBA 1EG4A 2JXWA 1F8AB 3KCEA 1O6WA 2JV4A 2JMFA 2M8JA 2ZAJA 2YSFA 2XP9A 2ZQUA 2YSBA 2ZQSA 3KADA 3ODKA 2M3OW 1WR7A 2BA1A 2F21A 3KAFA 2XP4A 3L4HA 2E45A 3KAHA 4REXA 1K9RA 4QIBA 2XP3A 2XP6A 3TCZA 3TC5A 1I5HW 3KABA 2Q5AA 3M85A 2DJYA 3M7NA 2JX8A 2DK7A 2ITKA 2ZQTA 2LAJA 2MDIA 1JMQA 2DK1A 2YSIA 3KAGA 2DWVA 1NMVA 2KXQA 2XPBA 2ZR5A 2ZR6A 1ZCNA 2XPAA 4E5RA 2ZR4A 1TK7A 1WMVA 2ZQVA 5CQ2A 1PINA 2XP7A 3KAIA 5AHTA 2XP5A 1YW5A 1EG3A 2YSHA 2L4JA 4U86A 2RE3A 3OOBA 3CNGA 1K9QA
chains in the Genus database with same CATH superfamily
2EZ5W 5E64A 2M8IA 2DMVA 4U85A 3FS8A 3LE4A 2XP8A 3NTPA 4U84A 1RP5A 2QRVA 3WH0A 2YSGA 3TDBA 3PQHA 5U47A 1EG4A 2JXWA 1F8AB 3KCEA 1O6WA 2JV4A 2JMFA 2M8JA 2ZAJA 2YSFA 2XP9A 2ZQUA 2YSBA 2ZQSA 3KADA 5E5WA 3ODKA 2M3OW 1WR7A 2BA1A 2F21A 3KAFA 2XP4A 3L4HA 2E45A 3KAHA 4REXA 1K9RA 4QIBA 2Y8NB 2XP3A 2XP6A 4A0TA 3TCZA 3TC5A 1I5HW 3KABA 2Q5AA 3LKXB 5E62A 3M85A 1FLCA 2DJYA 3M7NA 2JX8A 2DK7A 2OWOA 2ITKA 2WADA 2ZQTA 2LAJA 2MDIA 1JMQA 2DK1A 3FSCA 2YSIA 3KAGA 1NMVA 2DWVA 3LKXA 5E65A 2KXQA 2XPBA 2ZR5A 2ZR6A 1ZCNA 4A0UA 2XPAA 2YAJB 4E5RA 4GLXA 2ZR4A 1TK7A 1WMVA 2ZQVA 5CQ2A 1PINA 3MQHA 2XP7A 1TR8A 3KAIA 5AHTA 3MQGA 5E66A 2XP5A 1YW5A 3FSBA 3MCBA 1EG3A 2YSHA 2L4JA 4U86A 2RE3A 3MCBB 3OOBA 2WAEA 3CNGA 1K9QA
chains in the Genus database with same CATH topology
2EZ5W 5E64A 2M8IA 2DMVA 4U85A 3FS8A 3LE4A 2XP8A 3NTPA 4U84A 1RP5A 2QRVA 3WH0A 2YSGA 3TDBA 3PQHA 5U47A 1EG4A 2JXWA 1F8AB 3KCEA 1O6WA 2JV4A 2JMFA 2M8JA 2ZAJA 2YSFA 2XP9A 2ZQUA 2YSBA 2ZQSA 3KADA 5E5WA 3ODKA 2M3OW 1WR7A 2BA1A 2F21A 3KAFA 2XP4A 3L4HA 2E45A 3KAHA 4REXA 1K9RA 4QIBA 2Y8NB 2XP3A 2XP6A 4A0TA 3TCZA 3TC5A 1I5HW 3KABA 2Q5AA 3LKXB 5E62A 3M85A 1FLCA 2DJYA 3M7NA 2JX8A 2DK7A 2OWOA 2ITKA 2WADA 2ZQTA 2LAJA 2MDIA 1JMQA 2DK1A 3FSCA 2YSIA 3KAGA 1NMVA 2DWVA 3LKXA 5E65A 2KXQA 2XPBA 2ZR5A 2ZR6A 1ZCNA 4A0UA 2XPAA 2YAJB 4E5RA 4GLXA 2ZR4A 1TK7A 1WMVA 2ZQVA 5CQ2A 1PINA 3MQHA 2XP7A 1TR8A 3KAIA 5AHTA 3MQGA 5E66A 2XP5A 1YW5A 3FSBA 3MCBA 1EG3A 2YSHA 2L4JA 4U86A 2RE3A 3MCBB 3OOBA 2WAEA 3CNGA 1K9QA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2EZ5 W;  2M8I A;  2DMV A;  4U85 A;  3LE4 A;  2XP8 A;  3NTP A;  4U84 A;  3WH0 A;  2YSG A;  3TDB A;  1EG4 A;  2JXW A;  1F8A B;  3KCE A;  1O6W A;  2JV4 A;  2JMF A;  2M8J A;  2ZAJ A;  2YSF A;  2XP9 A;  2ZQU A;  2YSB A;  2ZQS A;  3KAD A;  3ODK A;  2M3O W;  1WR7 A;  2BA1 A;  2F21 A;  3KAF A;  2XP4 A;  3L4H A;  2E45 A;  3KAH A;  4REX A;  1K9R A;  4QIB A;  2XP3 A;  2XP6 A;  3TCZ A;  3TC5 A;  1I5H W;  3KAB A;  2Q5A A;  3M85 A;  2DJY A;  3M7N A;  2JX8 A;  2DK7 A;  2ITK A;  2ZQT A;  2LAJ A;  2MDI A;  1JMQ A;  2DK1 A;  2YSI A;  3KAG A;  2DWV A;  1NMV A;  2KXQ A;  2XPB A;  2ZR5 A;  2ZR6 A;  1ZCN A;  2XPA A;  4E5R A;  2ZR4 A;  1TK7 A;  1WMV A;  2ZQV A;  5CQ2 A;  1PIN A;  2XP7 A;  3KAI A;  5AHT A;  2XP5 A;  1YW5 A;  1EG3 A;  2YSH A;  2L4J A;  4U86 A;  2RE3 A;  3OOB A;  3CNG A;  1K9Q A; 
#chains in the Genus database with same CATH topology
 2EZ5 W;  5E64 A;  2M8I A;  2DMV A;  4U85 A;  3FS8 A;  3LE4 A;  2XP8 A;  3NTP A;  4U84 A;  1RP5 A;  2QRV A;  3WH0 A;  2YSG A;  3TDB A;  3PQH A;  5U47 A;  1EG4 A;  2JXW A;  1F8A B;  3KCE A;  1O6W A;  2JV4 A;  2JMF A;  2M8J A;  2ZAJ A;  2YSF A;  2XP9 A;  2ZQU A;  2YSB A;  2ZQS A;  3KAD A;  5E5W A;  3ODK A;  2M3O W;  1WR7 A;  2BA1 A;  2F21 A;  3KAF A;  2XP4 A;  3L4H A;  2E45 A;  3KAH A;  4REX A;  1K9R A;  4QIB A;  2Y8N B;  2XP3 A;  2XP6 A;  4A0T A;  3TCZ A;  3TC5 A;  1I5H W;  3KAB A;  2Q5A A;  3LKX B;  5E62 A;  3M85 A;  1FLC A;  2DJY A;  3M7N A;  2JX8 A;  2DK7 A;  2OWO A;  2ITK A;  2WAD A;  2ZQT A;  2LAJ A;  2MDI A;  1JMQ A;  2DK1 A;  3FSC A;  2YSI A;  3KAG A;  1NMV A;  2DWV A;  3LKX A;  5E65 A;  2KXQ A;  2XPB A;  2ZR5 A;  2ZR6 A;  1ZCN A;  4A0U A;  2XPA A;  2YAJ B;  4E5R A;  4GLX A;  2ZR4 A;  1TK7 A;  1WMV A;  2ZQV A;  5CQ2 A;  1PIN A;  3MQH A;  2XP7 A;  1TR8 A;  3KAI A;  5AHT A;  3MQG A;  5E66 A;  2XP5 A;  1YW5 A;  3FSB A;  3MCB A;  1EG3 A;  2YSH A;  2L4J A;  4U86 A;  2RE3 A;  3MCB B;  3OOB A;  2WAE A;  3CNG A;  1K9Q A; 
#chains in the Genus database with same CATH homology
 2EZ5 W;  5E64 A;  2M8I A;  2DMV A;  4U85 A;  3FS8 A;  3LE4 A;  2XP8 A;  3NTP A;  4U84 A;  1RP5 A;  2QRV A;  3WH0 A;  2YSG A;  3TDB A;  3PQH A;  5U47 A;  1EG4 A;  2JXW A;  1F8A B;  3KCE A;  1O6W A;  2JV4 A;  2JMF A;  2M8J A;  2ZAJ A;  2YSF A;  2XP9 A;  2ZQU A;  2YSB A;  2ZQS A;  3KAD A;  5E5W A;  3ODK A;  2M3O W;  1WR7 A;  2BA1 A;  2F21 A;  3KAF A;  2XP4 A;  3L4H A;  2E45 A;  3KAH A;  4REX A;  1K9R A;  4QIB A;  2Y8N B;  2XP3 A;  2XP6 A;  4A0T A;  3TCZ A;  3TC5 A;  1I5H W;  3KAB A;  2Q5A A;  3LKX B;  5E62 A;  3M85 A;  1FLC A;  2DJY A;  3M7N A;  2JX8 A;  2DK7 A;  2OWO A;  2ITK A;  2WAD A;  2ZQT A;  2LAJ A;  2MDI A;  1JMQ A;  2DK1 A;  3FSC A;  2YSI A;  3KAG A;  1NMV A;  2DWV A;  3LKX A;  5E65 A;  2KXQ A;  2XPB A;  2ZR5 A;  2ZR6 A;  1ZCN A;  4A0U A;  2XPA A;  2YAJ B;  4E5R A;  4GLX A;  2ZR4 A;  1TK7 A;  1WMV A;  2ZQV A;  5CQ2 A;  1PIN A;  3MQH A;  2XP7 A;  1TR8 A;  3KAI A;  5AHT A;  3MQG A;  5E66 A;  2XP5 A;  1YW5 A;  3FSB A;  3MCB A;  1EG3 A;  2YSH A;  2L4J A;  4U86 A;  2RE3 A;  3MCB B;  3OOB A;  2WAE A;  3CNG A;  1K9Q A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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