2E45A

Solution structure of fe65 ww domain
Total Genus 2
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
2
sequence length
50
structure length
50
Chain Sequence
DSFWNPNAFETDSDLPAGWMRVQDTSGTYYWHIPTGTTQWEPPGRASPSQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structure of Fe65 WW domain
rcsb
molecule tags Protein binding
source organism Homo sapiens
molecule keywords Amyloid beta A4 precursor protein-binding family B member 1
total genus 2
structure length 50
sequence length 50
ec nomenclature
pdb deposition date 2006-12-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00397 WW WW domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.70.10 Mainly Beta Single Sheet Ubiquitin Ligase Nedd4; Chain: W; Ubiquitin Ligase Nedd4; Chain: W; 2e45A01
3TCZA 2XPAA 2JV4A 4E5RA 2YSFA 2M3OW 3KABA 5AHTA 2Q5AA 3KAHA 2DK7A 2ZAJA 2ZQTA 3KAGA 2YSHA 3KAFA 3ODKA 2XP8A 2MDIA 1EG4A 1K9RA 2XP9A 1K9QA 2XP4A 3WH0A 2M8IA 2DWVA 2M8JA 1I5HW 2LAJA 2DK1A 3KADA 5CQ2A 2JXWA 2YSBA 1EG3A 3CNGA 2JX8A 2ZR6A 1PINA 2KXQA 3TC5A 2YSIA 2XP7A 2E45A 2XP6A 2XP5A 4U84A 1ZCNA 2DJYA 3LE4A 3OOBA 2ZQVA 1YW5A 2ZR5A 2BA1A 1WR7A 1TK7A 1NMVA 2ZQUA 3KCEA 2JMFA 2ITKA 2F21A 4U86A 3TDBA 1WMVA 2ZQSA 4QIBA 2XP3A 3KAIA 2XPBA 2ZR4A 2YSGA 3L4HA 3M85A 1JMQA 1F8AB 1O6WA 2EZ5W 2L4JA 4U85A 2DMVA 4REXA 3M7NA 3NTPA 2RE3A
chains in the Genus database with same CATH superfamily
3TCZA 2XPAA 2JV4A 4E5RA 2YSFA 2M3OW 3KABA 5AHTA 2Y8NB 2Q5AA 3KAHA 2DK7A 2ZAJA 1RP5A 3FSCA 2WADA 2ZQTA 2YAJB 3KAGA 1TR8A 3MQHA 4A0TA 2YSHA 3KAFA 5E62A 3ODKA 2XP8A 2MDIA 1EG4A 1K9RA 2XP9A 5E66A 1K9QA 2XP4A 2WAEA 3WH0A 2M8IA 5U47A 2DWVA 2M8JA 1I5HW 2LAJA 2DK1A 3KADA 5CQ2A 2JXWA 2YSBA 1EG3A 3CNGA 2JX8A 3FS8A 2ZR6A 2KXQA 1PINA 2QRVA 3TC5A 2YSIA 3PQHA 2XP7A 2E45A 2XP6A 2XP5A 4U84A 1ZCNA 2DJYA 3LE4A 3MQGA 3MCBA 3OOBA 2ZQVA 1YW5A 5E65A 2ZR5A 5E64A 2BA1A 3MCBB 5E5WA 1WR7A 4A0UA 3LKXA 1TK7A 1NMVA 3LKXB 2ZQUA 3KCEA 2JMFA 2ITKA 2F21A 4U86A 3FSBA 3TDBA 2OWOA 1WMVA 2ZQSA 4QIBA 2XP3A 3KAIA 2XPBA 2ZR4A 2YSGA 3L4HA 3M85A 1JMQA 1F8AB 1O6WA 2EZ5W 2L4JA 4U85A 2DMVA 4REXA 1FLCA 3M7NA 3NTPA 2RE3A 4GLXA
chains in the Genus database with same CATH topology
3TCZA 2XPAA 2JV4A 4E5RA 2YSFA 2M3OW 3KABA 5AHTA 2Y8NB 2Q5AA 3KAHA 2DK7A 2ZAJA 1RP5A 3FSCA 2WADA 2ZQTA 2YAJB 3KAGA 1TR8A 3MQHA 4A0TA 2YSHA 3KAFA 5E62A 3ODKA 2XP8A 2MDIA 1EG4A 1K9RA 2XP9A 5E66A 1K9QA 2XP4A 2WAEA 3WH0A 2M8IA 5U47A 2DWVA 2M8JA 1I5HW 2LAJA 2DK1A 3KADA 5CQ2A 2JXWA 2YSBA 1EG3A 3CNGA 2JX8A 3FS8A 2ZR6A 2KXQA 1PINA 2QRVA 3TC5A 2YSIA 3PQHA 2XP7A 2E45A 2XP6A 2XP5A 4U84A 1ZCNA 2DJYA 3LE4A 3MQGA 3MCBA 3OOBA 2ZQVA 1YW5A 5E65A 2ZR5A 5E64A 2BA1A 3MCBB 5E5WA 1WR7A 4A0UA 3LKXA 1TK7A 1NMVA 3LKXB 2ZQUA 3KCEA 2JMFA 2ITKA 2F21A 4U86A 3FSBA 3TDBA 2OWOA 1WMVA 2ZQSA 4QIBA 2XP3A 3KAIA 2XPBA 2ZR4A 2YSGA 3L4HA 3M85A 1JMQA 1F8AB 1O6WA 2EZ5W 2L4JA 4U85A 2DMVA 4REXA 1FLCA 3M7NA 3NTPA 2RE3A 4GLXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3TCZ A;  2XPA A;  2JV4 A;  4E5R A;  2YSF A;  2M3O W;  3KAB A;  5AHT A;  2Q5A A;  3KAH A;  2DK7 A;  2ZAJ A;  2ZQT A;  3KAG A;  2YSH A;  3KAF A;  3ODK A;  2XP8 A;  2MDI A;  1EG4 A;  1K9R A;  2XP9 A;  1K9Q A;  2XP4 A;  3WH0 A;  2M8I A;  2DWV A;  2M8J A;  1I5H W;  2LAJ A;  2DK1 A;  3KAD A;  5CQ2 A;  2JXW A;  2YSB A;  1EG3 A;  3CNG A;  2JX8 A;  2ZR6 A;  1PIN A;  2KXQ A;  3TC5 A;  2YSI A;  2XP7 A;  2E45 A;  2XP6 A;  2XP5 A;  4U84 A;  1ZCN A;  2DJY A;  3LE4 A;  3OOB A;  2ZQV A;  1YW5 A;  2ZR5 A;  2BA1 A;  1WR7 A;  1TK7 A;  1NMV A;  2ZQU A;  3KCE A;  2JMF A;  2ITK A;  2F21 A;  4U86 A;  3TDB A;  1WMV A;  2ZQS A;  4QIB A;  2XP3 A;  3KAI A;  2XPB A;  2ZR4 A;  2YSG A;  3L4H A;  3M85 A;  1JMQ A;  1F8A B;  1O6W A;  2EZ5 W;  2L4J A;  4U85 A;  2DMV A;  4REX A;  3M7N A;  3NTP A;  2RE3 A; 
#chains in the Genus database with same CATH topology
 3TCZ A;  2XPA A;  2JV4 A;  4E5R A;  2YSF A;  2M3O W;  3KAB A;  5AHT A;  2Y8N B;  2Q5A A;  3KAH A;  2DK7 A;  2ZAJ A;  1RP5 A;  3FSC A;  2WAD A;  2ZQT A;  2YAJ B;  3KAG A;  1TR8 A;  3MQH A;  4A0T A;  2YSH A;  3KAF A;  5E62 A;  3ODK A;  2XP8 A;  2MDI A;  1EG4 A;  1K9R A;  2XP9 A;  5E66 A;  1K9Q A;  2XP4 A;  2WAE A;  3WH0 A;  2M8I A;  5U47 A;  2DWV A;  2M8J A;  1I5H W;  2LAJ A;  2DK1 A;  3KAD A;  5CQ2 A;  2JXW A;  2YSB A;  1EG3 A;  3CNG A;  2JX8 A;  3FS8 A;  2ZR6 A;  2KXQ A;  1PIN A;  2QRV A;  3TC5 A;  2YSI A;  3PQH A;  2XP7 A;  2E45 A;  2XP6 A;  2XP5 A;  4U84 A;  1ZCN A;  2DJY A;  3LE4 A;  3MQG A;  3MCB A;  3OOB A;  2ZQV A;  1YW5 A;  5E65 A;  2ZR5 A;  5E64 A;  2BA1 A;  3MCB B;  5E5W A;  1WR7 A;  4A0U A;  3LKX A;  1TK7 A;  1NMV A;  3LKX B;  2ZQU A;  3KCE A;  2JMF A;  2ITK A;  2F21 A;  4U86 A;  3FSB A;  3TDB A;  2OWO A;  1WMV A;  2ZQS A;  4QIB A;  2XP3 A;  3KAI A;  2XPB A;  2ZR4 A;  2YSG A;  3L4H A;  3M85 A;  1JMQ A;  1F8A B;  1O6W A;  2EZ5 W;  2L4J A;  4U85 A;  2DMV A;  4REX A;  1FLC A;  3M7N A;  3NTP A;  2RE3 A;  4GLX A; 
#chains in the Genus database with same CATH homology
 3TCZ A;  2XPA A;  2JV4 A;  4E5R A;  2YSF A;  2M3O W;  3KAB A;  5AHT A;  2Y8N B;  2Q5A A;  3KAH A;  2DK7 A;  2ZAJ A;  1RP5 A;  3FSC A;  2WAD A;  2ZQT A;  2YAJ B;  3KAG A;  1TR8 A;  3MQH A;  4A0T A;  2YSH A;  3KAF A;  5E62 A;  3ODK A;  2XP8 A;  2MDI A;  1EG4 A;  1K9R A;  2XP9 A;  5E66 A;  1K9Q A;  2XP4 A;  2WAE A;  3WH0 A;  2M8I A;  5U47 A;  2DWV A;  2M8J A;  1I5H W;  2LAJ A;  2DK1 A;  3KAD A;  5CQ2 A;  2JXW A;  2YSB A;  1EG3 A;  3CNG A;  2JX8 A;  3FS8 A;  2ZR6 A;  2KXQ A;  1PIN A;  2QRV A;  3TC5 A;  2YSI A;  3PQH A;  2XP7 A;  2E45 A;  2XP6 A;  2XP5 A;  4U84 A;  1ZCN A;  2DJY A;  3LE4 A;  3MQG A;  3MCB A;  3OOB A;  2ZQV A;  1YW5 A;  5E65 A;  2ZR5 A;  5E64 A;  2BA1 A;  3MCB B;  5E5W A;  1WR7 A;  4A0U A;  3LKX A;  1TK7 A;  1NMV A;  3LKX B;  2ZQU A;  3KCE A;  2JMF A;  2ITK A;  2F21 A;  4U86 A;  3FSB A;  3TDB A;  2OWO A;  1WMV A;  2ZQS A;  4QIB A;  2XP3 A;  3KAI A;  2XPB A;  2ZR4 A;  2YSG A;  3L4H A;  3M85 A;  1JMQ A;  1F8A B;  1O6W A;  2EZ5 W;  2L4J A;  4U85 A;  2DMV A;  4REX A;  1FLC A;  3M7N A;  3NTP A;  2RE3 A;  4GLX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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