2EZ5W

Solution structure of the dnedd4 ww3* domain- comm lpsy peptide complex
Total Genus 5
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
5
sequence length
46
structure length
46
Chain Sequence
GPLGSGEEEPLPPRWSMQVAPNGRTFFIDHASRRTTWIDPRNGRAS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Signalling protein,ligase
source organism Drosophila melanogaster
publication title Structural Determinants for High-Affinity Binding in a Nedd4 WW3(*) Domain-Comm PY Motif Complex
pubmed doi rcsb
molecule keywords E3 ubiquitin-protein ligase NEDD4
total genus 5
structure length 46
sequence length 46
ec nomenclature ec 2.3.2.26: HECT-type E3 ubiquitin transferase.
pdb deposition date 2005-11-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
W PF00397 WW WW domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.70.10 Mainly Beta Single Sheet Ubiquitin Ligase Nedd4; Chain: W; Ubiquitin Ligase Nedd4; Chain: W; 2ez5W01
2RE3A 2MDIA 2XP4A 5AHTA 1WR7A 1K9RA 2YSGA 2DMVA 2M8JA 1ZCNA 2XPBA 2YSIA 2YSHA 3NTPA 3M85A 2ZR5A 3TC5A 3OOBA 2XP8A 2M8IA 3KAHA 2DJYA 3LE4A 2ZQTA 2ZR4A 4U86A 2XP3A 1EG4A 1JMQA 2XP5A 1NMVA 3TDBA 3WH0A 1K9QA 2ZQVA 2E45A 1YW5A 2KXQA 1I5HW 1TK7A 2EZ5W 3CNGA 1EG3A 2ZR6A 2F21A 2XP6A 4E5RA 2XP7A 2ZQSA 1O6WA 2YSBA 2LAJA 3KAIA 1WMVA 3TCZA 2BA1A 4QIBA 2M3OW 3M7NA 5CQ2A 3KADA 3KABA 2DWVA 4REXA 2JV4A 1PINA 2L4JA 1F8AB 3KAFA 3ODKA 2ITKA 2JX8A 2Q5AA 2JMFA 3KCEA 2DK7A 2ZAJA 3KAGA 2JXWA 2XPAA 2XP9A 2YSFA 2ZQUA 2DK1A 4U84A 3L4HA 4U85A
chains in the Genus database with same CATH superfamily
2RE3A 2MDIA 2QRVA 2XP4A 5AHTA 1WR7A 1K9RA 3FS8A 3MCBA 2YSGA 4A0UA 2DMVA 2M8JA 1ZCNA 2XPBA 5E5WA 2YSIA 2YSHA 3MQGA 3NTPA 3PQHA 3M85A 2ZR5A 3TC5A 3OOBA 2XP8A 2M8IA 2YAJB 3KAHA 2DJYA 2OWOA 3LE4A 2ZQTA 2ZR4A 4U86A 2XP3A 1EG4A 1JMQA 2XP5A 1NMVA 3TDBA 3WH0A 5U47A 1K9QA 2ZQVA 5E66A 2E45A 1YW5A 2KXQA 1I5HW 3MQHA 1TK7A 2EZ5W 3LKXB 3CNGA 1EG3A 5E64A 5E62A 2ZR6A 3MCBB 1FLCA 2F21A 1TR8A 2XP6A 4E5RA 2XP7A 2ZQSA 1O6WA 2YSBA 2LAJA 3KAIA 1WMVA 4GLXA 3TCZA 2Y8NB 2BA1A 1RP5A 4QIBA 2M3OW 3M7NA 5CQ2A 3KADA 3FSBA 3KABA 2DWVA 3FSCA 2JV4A 2WAEA 4REXA 3LKXA 1PINA 2L4JA 4A0TA 1F8AB 3KAFA 3ODKA 2ITKA 2JX8A 2Q5AA 2JMFA 3KCEA 2DK7A 2ZAJA 3KAGA 2JXWA 2XPAA 2XP9A 2YSFA 5E65A 2ZQUA 2DK1A 4U84A 2WADA 3L4HA 4U85A
chains in the Genus database with same CATH topology
2RE3A 2MDIA 2QRVA 2XP4A 5AHTA 1WR7A 1K9RA 3FS8A 3MCBA 2YSGA 4A0UA 2DMVA 2M8JA 1ZCNA 2XPBA 5E5WA 2YSIA 2YSHA 3MQGA 3NTPA 3PQHA 3M85A 2ZR5A 3TC5A 3OOBA 2XP8A 2M8IA 2YAJB 3KAHA 2DJYA 2OWOA 3LE4A 2ZQTA 2ZR4A 4U86A 2XP3A 1EG4A 1JMQA 2XP5A 1NMVA 3TDBA 3WH0A 5U47A 1K9QA 2ZQVA 5E66A 2E45A 1YW5A 2KXQA 1I5HW 3MQHA 1TK7A 2EZ5W 3LKXB 3CNGA 1EG3A 5E64A 5E62A 2ZR6A 3MCBB 1FLCA 2F21A 1TR8A 2XP6A 4E5RA 2XP7A 2ZQSA 1O6WA 2YSBA 2LAJA 3KAIA 1WMVA 4GLXA 3TCZA 2Y8NB 2BA1A 1RP5A 4QIBA 2M3OW 3M7NA 5CQ2A 3KADA 3FSBA 3KABA 2DWVA 3FSCA 2JV4A 2WAEA 4REXA 3LKXA 1PINA 2L4JA 4A0TA 1F8AB 3KAFA 3ODKA 2ITKA 2JX8A 2Q5AA 2JMFA 3KCEA 2DK7A 2ZAJA 3KAGA 2JXWA 2XPAA 2XP9A 2YSFA 5E65A 2ZQUA 2DK1A 4U84A 2WADA 3L4HA 4U85A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2RE3 A;  2MDI A;  2XP4 A;  5AHT A;  1WR7 A;  1K9R A;  2YSG A;  2DMV A;  2M8J A;  1ZCN A;  2XPB A;  2YSI A;  2YSH A;  3NTP A;  3M85 A;  2ZR5 A;  3TC5 A;  3OOB A;  2XP8 A;  2M8I A;  3KAH A;  2DJY A;  3LE4 A;  2ZQT A;  2ZR4 A;  4U86 A;  2XP3 A;  1EG4 A;  1JMQ A;  2XP5 A;  1NMV A;  3TDB A;  3WH0 A;  1K9Q A;  2ZQV A;  2E45 A;  1YW5 A;  2KXQ A;  1I5H W;  1TK7 A;  2EZ5 W;  3CNG A;  1EG3 A;  2ZR6 A;  2F21 A;  2XP6 A;  4E5R A;  2XP7 A;  2ZQS A;  1O6W A;  2YSB A;  2LAJ A;  3KAI A;  1WMV A;  3TCZ A;  2BA1 A;  4QIB A;  2M3O W;  3M7N A;  5CQ2 A;  3KAD A;  3KAB A;  2DWV A;  4REX A;  2JV4 A;  1PIN A;  2L4J A;  1F8A B;  3KAF A;  3ODK A;  2ITK A;  2JX8 A;  2Q5A A;  2JMF A;  3KCE A;  2DK7 A;  2ZAJ A;  3KAG A;  2JXW A;  2XPA A;  2XP9 A;  2YSF A;  2ZQU A;  2DK1 A;  4U84 A;  3L4H A;  4U85 A; 
#chains in the Genus database with same CATH topology
 2RE3 A;  2MDI A;  2QRV A;  2XP4 A;  5AHT A;  1WR7 A;  1K9R A;  3FS8 A;  3MCB A;  2YSG A;  4A0U A;  2DMV A;  2M8J A;  1ZCN A;  2XPB A;  5E5W A;  2YSI A;  2YSH A;  3MQG A;  3NTP A;  3PQH A;  3M85 A;  2ZR5 A;  3TC5 A;  3OOB A;  2XP8 A;  2M8I A;  2YAJ B;  3KAH A;  2DJY A;  2OWO A;  3LE4 A;  2ZQT A;  2ZR4 A;  4U86 A;  2XP3 A;  1EG4 A;  1JMQ A;  2XP5 A;  1NMV A;  3TDB A;  3WH0 A;  5U47 A;  1K9Q A;  2ZQV A;  5E66 A;  2E45 A;  1YW5 A;  2KXQ A;  1I5H W;  3MQH A;  1TK7 A;  2EZ5 W;  3LKX B;  3CNG A;  1EG3 A;  5E64 A;  5E62 A;  2ZR6 A;  3MCB B;  1FLC A;  2F21 A;  1TR8 A;  2XP6 A;  4E5R A;  2XP7 A;  2ZQS A;  1O6W A;  2YSB A;  2LAJ A;  3KAI A;  1WMV A;  4GLX A;  3TCZ A;  2Y8N B;  2BA1 A;  1RP5 A;  4QIB A;  2M3O W;  3M7N A;  5CQ2 A;  3KAD A;  3FSB A;  3KAB A;  2DWV A;  3FSC A;  2JV4 A;  2WAE A;  4REX A;  3LKX A;  1PIN A;  2L4J A;  4A0T A;  1F8A B;  3KAF A;  3ODK A;  2ITK A;  2JX8 A;  2Q5A A;  2JMF A;  3KCE A;  2DK7 A;  2ZAJ A;  3KAG A;  2JXW A;  2XPA A;  2XP9 A;  2YSF A;  5E65 A;  2ZQU A;  2DK1 A;  4U84 A;  2WAD A;  3L4H A;  4U85 A; 
#chains in the Genus database with same CATH homology
 2RE3 A;  2MDI A;  2QRV A;  2XP4 A;  5AHT A;  1WR7 A;  1K9R A;  3FS8 A;  3MCB A;  2YSG A;  4A0U A;  2DMV A;  2M8J A;  1ZCN A;  2XPB A;  5E5W A;  2YSI A;  2YSH A;  3MQG A;  3NTP A;  3PQH A;  3M85 A;  2ZR5 A;  3TC5 A;  3OOB A;  2XP8 A;  2M8I A;  2YAJ B;  3KAH A;  2DJY A;  2OWO A;  3LE4 A;  2ZQT A;  2ZR4 A;  4U86 A;  2XP3 A;  1EG4 A;  1JMQ A;  2XP5 A;  1NMV A;  3TDB A;  3WH0 A;  5U47 A;  1K9Q A;  2ZQV A;  5E66 A;  2E45 A;  1YW5 A;  2KXQ A;  1I5H W;  3MQH A;  1TK7 A;  2EZ5 W;  3LKX B;  3CNG A;  1EG3 A;  5E64 A;  5E62 A;  2ZR6 A;  3MCB B;  1FLC A;  2F21 A;  1TR8 A;  2XP6 A;  4E5R A;  2XP7 A;  2ZQS A;  1O6W A;  2YSB A;  2LAJ A;  3KAI A;  1WMV A;  4GLX A;  3TCZ A;  2Y8N B;  2BA1 A;  1RP5 A;  4QIB A;  2M3O W;  3M7N A;  5CQ2 A;  3KAD A;  3FSB A;  3KAB A;  2DWV A;  3FSC A;  2JV4 A;  2WAE A;  4REX A;  3LKX A;  1PIN A;  2L4J A;  4A0T A;  1F8A B;  3KAF A;  3ODK A;  2ITK A;  2JX8 A;  2Q5A A;  2JMF A;  3KCE A;  2DK7 A;  2ZAJ A;  3KAG A;  2JXW A;  2XPA A;  2XP9 A;  2YSF A;  5E65 A;  2ZQU A;  2DK1 A;  4U84 A;  2WAD A;  3L4H A;  4U85 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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