2LAJA

Third ww domain of human nedd4l in complex with doubly phosphorylated human smad3 derived peptide
Total Genus 4
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
4
sequence length
40
structure length
40
Chain Sequence
QSFLPPGWEMRIAPNGRPFFYDHNTKTTTWEDPRLKFPVH
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title A Smad action turnover switch operated by WW domain readers of a phosphoserine code.
pubmed doi rcsb
molecule tags Ligase/transcription regulator
source organism Homo sapiens
molecule keywords E3 ubiquitin-protein ligase NEDD4-like
total genus 4
structure length 40
sequence length 40
ec nomenclature ec 2.3.2.26: HECT-type E3 ubiquitin transferase.
pdb deposition date 2011-03-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00397 WW WW domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.70.10 Mainly Beta Single Sheet Ubiquitin Ligase Nedd4; Chain: W; Ubiquitin Ligase Nedd4; Chain: W; 2lajA01
1O6WA 2YSBA 4U85A 3TCZA 3M85A 1WR7A 2XP8A 2ZQTA 2DMVA 1NMVA 3KCEA 2Q5AA 2DK7A 2EZ5W 2XP9A 2YSHA 2BA1A 5CQ2A 2XP3A 4U86A 1WMVA 2LAJA 3TDBA 3ODKA 3L4HA 1F8AB 3KAFA 2JV4A 2JXWA 2ZR5A 1K9RA 2DJYA 2RE3A 2ZQVA 2KXQA 2ZR4A 2DK1A 2ZQUA 2M8JA 3M7NA 1EG3A 1ZCNA 2XPAA 2YSGA 2ZQSA 4REXA 2XPBA 2XP7A 2F21A 2ITKA 3KAHA 3KABA 2M8IA 2L4JA 2ZR6A 2MDIA 3KADA 3LE4A 3KAIA 2ZAJA 2XP6A 1K9QA 2XP4A 2E45A 5AHTA 1EG4A 3CNGA 1TK7A 2YSIA 3WH0A 4QIBA 3NTPA 1I5HW 2JX8A 4E5RA 2XP5A 2YSFA 4U84A 1YW5A 2JMFA 3KAGA 1JMQA 2M3OW 3TC5A 2DWVA 3OOBA 1PINA
chains in the Genus database with same CATH superfamily
1O6WA 2YSBA 4U85A 3TCZA 3FSCA 3M85A 1WR7A 2XP8A 2ZQTA 2DMVA 1NMVA 3KCEA 2Q5AA 2DK7A 2EZ5W 2XP9A 3FS8A 2YSHA 2BA1A 5CQ2A 2XP3A 4U86A 1WMVA 5E62A 2LAJA 3MCBA 3TDBA 3ODKA 1FLCA 3L4HA 3MCBB 1F8AB 2QRVA 2JV4A 3KAFA 2JXWA 2ZR5A 1K9RA 4GLXA 2DJYA 2RE3A 2ZQVA 2KXQA 1RP5A 2ZR4A 4A0TA 2DK1A 2ZQUA 2M8JA 2WADA 3M7NA 1EG3A 1ZCNA 2XPAA 2YSGA 2ZQSA 4REXA 5U47A 2XPBA 2XP7A 2F21A 2ITKA 3KAHA 3KABA 2M8IA 2L4JA 2ZR6A 2MDIA 3KADA 3LE4A 3KAIA 2ZAJA 2XP6A 1K9QA 2XP4A 2E45A 5AHTA 3MQGA 1EG4A 3CNGA 1TK7A 2Y8NB 2YSIA 5E65A 3WH0A 4QIBA 3NTPA 1I5HW 2JX8A 2YAJB 4E5RA 2XP5A 2YSFA 4U84A 4A0UA 3MQHA 5E64A 1YW5A 2JMFA 3KAGA 1JMQA 3FSBA 3LKXA 2WAEA 2M3OW 3OOBA 3PQHA 3TC5A 2OWOA 3LKXB 5E66A 2DWVA 1TR8A 1PINA 5E5WA
chains in the Genus database with same CATH topology
1O6WA 2YSBA 4U85A 3TCZA 3FSCA 3M85A 1WR7A 2XP8A 2ZQTA 2DMVA 1NMVA 3KCEA 2Q5AA 2DK7A 2EZ5W 2XP9A 3FS8A 2YSHA 2BA1A 5CQ2A 2XP3A 4U86A 1WMVA 5E62A 2LAJA 3MCBA 3TDBA 3ODKA 1FLCA 3L4HA 3MCBB 1F8AB 2QRVA 2JV4A 3KAFA 2JXWA 2ZR5A 1K9RA 4GLXA 2DJYA 2RE3A 2ZQVA 2KXQA 1RP5A 2ZR4A 4A0TA 2DK1A 2ZQUA 2M8JA 2WADA 3M7NA 1EG3A 1ZCNA 2XPAA 2YSGA 2ZQSA 4REXA 5U47A 2XPBA 2XP7A 2F21A 2ITKA 3KAHA 3KABA 2M8IA 2L4JA 2ZR6A 2MDIA 3KADA 3LE4A 3KAIA 2ZAJA 2XP6A 1K9QA 2XP4A 2E45A 5AHTA 3MQGA 1EG4A 3CNGA 1TK7A 2Y8NB 2YSIA 5E65A 3WH0A 4QIBA 3NTPA 1I5HW 2JX8A 2YAJB 4E5RA 2XP5A 2YSFA 4U84A 4A0UA 3MQHA 5E64A 1YW5A 2JMFA 3KAGA 1JMQA 3FSBA 3LKXA 2WAEA 2M3OW 3OOBA 3PQHA 3TC5A 2OWOA 3LKXB 5E66A 2DWVA 1TR8A 1PINA 5E5WA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1O6W A;  2YSB A;  4U85 A;  3TCZ A;  3M85 A;  1WR7 A;  2XP8 A;  2ZQT A;  2DMV A;  1NMV A;  3KCE A;  2Q5A A;  2DK7 A;  2EZ5 W;  2XP9 A;  2YSH A;  2BA1 A;  5CQ2 A;  2XP3 A;  4U86 A;  1WMV A;  2LAJ A;  3TDB A;  3ODK A;  3L4H A;  1F8A B;  3KAF A;  2JV4 A;  2JXW A;  2ZR5 A;  1K9R A;  2DJY A;  2RE3 A;  2ZQV A;  2KXQ A;  2ZR4 A;  2DK1 A;  2ZQU A;  2M8J A;  3M7N A;  1EG3 A;  1ZCN A;  2XPA A;  2YSG A;  2ZQS A;  4REX A;  2XPB A;  2XP7 A;  2F21 A;  2ITK A;  3KAH A;  3KAB A;  2M8I A;  2L4J A;  2ZR6 A;  2MDI A;  3KAD A;  3LE4 A;  3KAI A;  2ZAJ A;  2XP6 A;  1K9Q A;  2XP4 A;  2E45 A;  5AHT A;  1EG4 A;  3CNG A;  1TK7 A;  2YSI A;  3WH0 A;  4QIB A;  3NTP A;  1I5H W;  2JX8 A;  4E5R A;  2XP5 A;  2YSF A;  4U84 A;  1YW5 A;  2JMF A;  3KAG A;  1JMQ A;  2M3O W;  3TC5 A;  2DWV A;  3OOB A;  1PIN A; 
#chains in the Genus database with same CATH topology
 1O6W A;  2YSB A;  4U85 A;  3TCZ A;  3FSC A;  3M85 A;  1WR7 A;  2XP8 A;  2ZQT A;  2DMV A;  1NMV A;  3KCE A;  2Q5A A;  2DK7 A;  2EZ5 W;  2XP9 A;  3FS8 A;  2YSH A;  2BA1 A;  5CQ2 A;  2XP3 A;  4U86 A;  1WMV A;  5E62 A;  2LAJ A;  3MCB A;  3TDB A;  3ODK A;  1FLC A;  3L4H A;  3MCB B;  1F8A B;  2QRV A;  2JV4 A;  3KAF A;  2JXW A;  2ZR5 A;  1K9R A;  4GLX A;  2DJY A;  2RE3 A;  2ZQV A;  2KXQ A;  1RP5 A;  2ZR4 A;  4A0T A;  2DK1 A;  2ZQU A;  2M8J A;  2WAD A;  3M7N A;  1EG3 A;  1ZCN A;  2XPA A;  2YSG A;  2ZQS A;  4REX A;  5U47 A;  2XPB A;  2XP7 A;  2F21 A;  2ITK A;  3KAH A;  3KAB A;  2M8I A;  2L4J A;  2ZR6 A;  2MDI A;  3KAD A;  3LE4 A;  3KAI A;  2ZAJ A;  2XP6 A;  1K9Q A;  2XP4 A;  2E45 A;  5AHT A;  3MQG A;  1EG4 A;  3CNG A;  1TK7 A;  2Y8N B;  2YSI A;  5E65 A;  3WH0 A;  4QIB A;  3NTP A;  1I5H W;  2JX8 A;  2YAJ B;  4E5R A;  2XP5 A;  2YSF A;  4U84 A;  4A0U A;  3MQH A;  5E64 A;  1YW5 A;  2JMF A;  3KAG A;  1JMQ A;  3FSB A;  3LKX A;  2WAE A;  2M3O W;  3OOB A;  3PQH A;  3TC5 A;  2OWO A;  3LKX B;  5E66 A;  2DWV A;  1TR8 A;  1PIN A;  5E5W A; 
#chains in the Genus database with same CATH homology
 1O6W A;  2YSB A;  4U85 A;  3TCZ A;  3FSC A;  3M85 A;  1WR7 A;  2XP8 A;  2ZQT A;  2DMV A;  1NMV A;  3KCE A;  2Q5A A;  2DK7 A;  2EZ5 W;  2XP9 A;  3FS8 A;  2YSH A;  2BA1 A;  5CQ2 A;  2XP3 A;  4U86 A;  1WMV A;  5E62 A;  2LAJ A;  3MCB A;  3TDB A;  3ODK A;  1FLC A;  3L4H A;  3MCB B;  1F8A B;  2QRV A;  2JV4 A;  3KAF A;  2JXW A;  2ZR5 A;  1K9R A;  4GLX A;  2DJY A;  2RE3 A;  2ZQV A;  2KXQ A;  1RP5 A;  2ZR4 A;  4A0T A;  2DK1 A;  2ZQU A;  2M8J A;  2WAD A;  3M7N A;  1EG3 A;  1ZCN A;  2XPA A;  2YSG A;  2ZQS A;  4REX A;  5U47 A;  2XPB A;  2XP7 A;  2F21 A;  2ITK A;  3KAH A;  3KAB A;  2M8I A;  2L4J A;  2ZR6 A;  2MDI A;  3KAD A;  3LE4 A;  3KAI A;  2ZAJ A;  2XP6 A;  1K9Q A;  2XP4 A;  2E45 A;  5AHT A;  3MQG A;  1EG4 A;  3CNG A;  1TK7 A;  2Y8N B;  2YSI A;  5E65 A;  3WH0 A;  4QIB A;  3NTP A;  1I5H W;  2JX8 A;  2YAJ B;  4E5R A;  2XP5 A;  2YSF A;  4U84 A;  4A0U A;  3MQH A;  5E64 A;  1YW5 A;  2JMF A;  3KAG A;  1JMQ A;  3FSB A;  3LKX A;  2WAE A;  2M3O W;  3OOB A;  3PQH A;  3TC5 A;  2OWO A;  3LKX B;  5E66 A;  2DWV A;  1TR8 A;  1PIN A;  5E5W A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...