2M3OW

Structure and dynamics of a human nedd4 ww domain-enac complex
Total Genus 4
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
4
sequence length
43
structure length
43
Chain Sequence
GSMEQGFLPKGWEVRHAPNGRPFFIDHNTKTTTWEDPRLKIPA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Peptide binding protein/protein binding
source organism Homo sapiens
publication title Structure and dynamics of human Nedd4-1 WW3 in complex with the alpha ENaC PY motif.
pubmed doi rcsb
molecule keywords E3 ubiquitin-protein ligase NEDD4
total genus 4
structure length 43
sequence length 43
ec nomenclature ec 2.3.2.26: HECT-type E3 ubiquitin transferase.
pdb deposition date 2013-01-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
W PF00397 WW WW domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.70.10 Mainly Beta Single Sheet Ubiquitin Ligase Nedd4; Chain: W; Ubiquitin Ligase Nedd4; Chain: W; 2m3oW01
2LAJA 2YSFA 3TC5A 2DJYA 1TK7A 1F8AB 2ZQTA 4E5RA 2YSIA 2XP5A 2ZQSA 2ZR5A 2MDIA 2XP3A 2JXWA 5AHTA 3OOBA 3TDBA 3WH0A 2JMFA 2KXQA 3TCZA 3KABA 4U84A 2F21A 2ITKA 2ZR6A 2ZAJA 4REXA 1NMVA 2XP4A 3KAFA 2DK1A 3L4HA 4QIBA 3KAHA 4U86A 1K9RA 2EZ5W 1PINA 2DWVA 2ZQVA 3KADA 2M8JA 1JMQA 1ZCNA 1EG4A 3KAGA 2M8IA 2L4JA 2M3OW 3NTPA 2XPAA 2BA1A 2ZR4A 2Q5AA 1I5HW 3KCEA 2DK7A 2RE3A 2YSBA 4U85A 1WMVA 2XP8A 5CQ2A 1K9QA 1EG3A 2DMVA 3ODKA 3KAIA 3M85A 2ZQUA 2XPBA 1WR7A 3M7NA 2JX8A 2XP9A 3LE4A 3CNGA 2E45A 2YSHA 1O6WA 2XP7A 2JV4A 1YW5A 2XP6A 2YSGA
chains in the Genus database with same CATH superfamily
2LAJA 2YSFA 3TC5A 2OWOA 2DJYA 3FS8A 2WAEA 4A0UA 1TK7A 1F8AB 2ZQTA 4E5RA 2YSIA 2XP5A 2ZQSA 5E64A 2ZR5A 2MDIA 2XP3A 2JXWA 3FSBA 5AHTA 3OOBA 3TDBA 3WH0A 3PQHA 1TR8A 2JMFA 1FLCA 5E5WA 2KXQA 3TCZA 3KABA 4U84A 2F21A 2ITKA 2ZR6A 2ZAJA 4REXA 1NMVA 2XP4A 3KAFA 2DK1A 3L4HA 4QIBA 3KAHA 1RP5A 4U86A 3MCBA 1K9RA 2EZ5W 3LKXB 1PINA 2DWVA 2ZQVA 3KADA 2M8JA 1JMQA 1ZCNA 1EG4A 3KAGA 2WADA 2M8IA 2L4JA 2M3OW 3NTPA 2XPAA 5U47A 4GLXA 2BA1A 2ZR4A 2Q5AA 5E66A 1I5HW 5E65A 3KCEA 2DK7A 4A0TA 2RE3A 2YSBA 3MQHA 4U85A 1WMVA 2XP8A 5CQ2A 3FSCA 1K9QA 1EG3A 2DMVA 3ODKA 3KAIA 3M85A 2QRVA 2ZQUA 2XPBA 2YAJB 5E62A 1WR7A 3M7NA 2JX8A 3MQGA 2XP9A 3LKXA 3LE4A 3CNGA 2E45A 2YSHA 1O6WA 2Y8NB 2XP7A 2JV4A 1YW5A 2XP6A 2YSGA 3MCBB
chains in the Genus database with same CATH topology
2LAJA 2YSFA 3TC5A 2OWOA 2DJYA 3FS8A 2WAEA 4A0UA 1TK7A 1F8AB 2ZQTA 4E5RA 2YSIA 2XP5A 2ZQSA 5E64A 2ZR5A 2MDIA 2XP3A 2JXWA 3FSBA 5AHTA 3OOBA 3TDBA 3WH0A 3PQHA 1TR8A 2JMFA 1FLCA 5E5WA 2KXQA 3TCZA 3KABA 4U84A 2F21A 2ITKA 2ZR6A 2ZAJA 4REXA 1NMVA 2XP4A 3KAFA 2DK1A 3L4HA 4QIBA 3KAHA 1RP5A 4U86A 3MCBA 1K9RA 2EZ5W 3LKXB 1PINA 2DWVA 2ZQVA 3KADA 2M8JA 1JMQA 1ZCNA 1EG4A 3KAGA 2WADA 2M8IA 2L4JA 2M3OW 3NTPA 2XPAA 5U47A 4GLXA 2BA1A 2ZR4A 2Q5AA 5E66A 1I5HW 5E65A 3KCEA 2DK7A 4A0TA 2RE3A 2YSBA 3MQHA 4U85A 1WMVA 2XP8A 5CQ2A 3FSCA 1K9QA 1EG3A 2DMVA 3ODKA 3KAIA 3M85A 2QRVA 2ZQUA 2XPBA 2YAJB 5E62A 1WR7A 3M7NA 2JX8A 3MQGA 2XP9A 3LKXA 3LE4A 3CNGA 2E45A 2YSHA 1O6WA 2Y8NB 2XP7A 2JV4A 1YW5A 2XP6A 2YSGA 3MCBB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2LAJ A;  2YSF A;  3TC5 A;  2DJY A;  1TK7 A;  1F8A B;  2ZQT A;  4E5R A;  2YSI A;  2XP5 A;  2ZQS A;  2ZR5 A;  2MDI A;  2XP3 A;  2JXW A;  5AHT A;  3OOB A;  3TDB A;  3WH0 A;  2JMF A;  2KXQ A;  3TCZ A;  3KAB A;  4U84 A;  2F21 A;  2ITK A;  2ZR6 A;  2ZAJ A;  4REX A;  1NMV A;  2XP4 A;  3KAF A;  2DK1 A;  3L4H A;  4QIB A;  3KAH A;  4U86 A;  1K9R A;  2EZ5 W;  1PIN A;  2DWV A;  2ZQV A;  3KAD A;  2M8J A;  1JMQ A;  1ZCN A;  1EG4 A;  3KAG A;  2M8I A;  2L4J A;  2M3O W;  3NTP A;  2XPA A;  2BA1 A;  2ZR4 A;  2Q5A A;  1I5H W;  3KCE A;  2DK7 A;  2RE3 A;  2YSB A;  4U85 A;  1WMV A;  2XP8 A;  5CQ2 A;  1K9Q A;  1EG3 A;  2DMV A;  3ODK A;  3KAI A;  3M85 A;  2ZQU A;  2XPB A;  1WR7 A;  3M7N A;  2JX8 A;  2XP9 A;  3LE4 A;  3CNG A;  2E45 A;  2YSH A;  1O6W A;  2XP7 A;  2JV4 A;  1YW5 A;  2XP6 A;  2YSG A; 
#chains in the Genus database with same CATH topology
 2LAJ A;  2YSF A;  3TC5 A;  2OWO A;  2DJY A;  3FS8 A;  2WAE A;  4A0U A;  1TK7 A;  1F8A B;  2ZQT A;  4E5R A;  2YSI A;  2XP5 A;  2ZQS A;  5E64 A;  2ZR5 A;  2MDI A;  2XP3 A;  2JXW A;  3FSB A;  5AHT A;  3OOB A;  3TDB A;  3WH0 A;  3PQH A;  1TR8 A;  2JMF A;  1FLC A;  5E5W A;  2KXQ A;  3TCZ A;  3KAB A;  4U84 A;  2F21 A;  2ITK A;  2ZR6 A;  2ZAJ A;  4REX A;  1NMV A;  2XP4 A;  3KAF A;  2DK1 A;  3L4H A;  4QIB A;  3KAH A;  1RP5 A;  4U86 A;  3MCB A;  1K9R A;  2EZ5 W;  3LKX B;  1PIN A;  2DWV A;  2ZQV A;  3KAD A;  2M8J A;  1JMQ A;  1ZCN A;  1EG4 A;  3KAG A;  2WAD A;  2M8I A;  2L4J A;  2M3O W;  3NTP A;  2XPA A;  5U47 A;  4GLX A;  2BA1 A;  2ZR4 A;  2Q5A A;  5E66 A;  1I5H W;  5E65 A;  3KCE A;  2DK7 A;  4A0T A;  2RE3 A;  2YSB A;  3MQH A;  4U85 A;  1WMV A;  2XP8 A;  5CQ2 A;  3FSC A;  1K9Q A;  1EG3 A;  2DMV A;  3ODK A;  3KAI A;  3M85 A;  2QRV A;  2ZQU A;  2XPB A;  2YAJ B;  5E62 A;  1WR7 A;  3M7N A;  2JX8 A;  3MQG A;  2XP9 A;  3LKX A;  3LE4 A;  3CNG A;  2E45 A;  2YSH A;  1O6W A;  2Y8N B;  2XP7 A;  2JV4 A;  1YW5 A;  2XP6 A;  2YSG A;  3MCB B; 
#chains in the Genus database with same CATH homology
 2LAJ A;  2YSF A;  3TC5 A;  2OWO A;  2DJY A;  3FS8 A;  2WAE A;  4A0U A;  1TK7 A;  1F8A B;  2ZQT A;  4E5R A;  2YSI A;  2XP5 A;  2ZQS A;  5E64 A;  2ZR5 A;  2MDI A;  2XP3 A;  2JXW A;  3FSB A;  5AHT A;  3OOB A;  3TDB A;  3WH0 A;  3PQH A;  1TR8 A;  2JMF A;  1FLC A;  5E5W A;  2KXQ A;  3TCZ A;  3KAB A;  4U84 A;  2F21 A;  2ITK A;  2ZR6 A;  2ZAJ A;  4REX A;  1NMV A;  2XP4 A;  3KAF A;  2DK1 A;  3L4H A;  4QIB A;  3KAH A;  1RP5 A;  4U86 A;  3MCB A;  1K9R A;  2EZ5 W;  3LKX B;  1PIN A;  2DWV A;  2ZQV A;  3KAD A;  2M8J A;  1JMQ A;  1ZCN A;  1EG4 A;  3KAG A;  2WAD A;  2M8I A;  2L4J A;  2M3O W;  3NTP A;  2XPA A;  5U47 A;  4GLX A;  2BA1 A;  2ZR4 A;  2Q5A A;  5E66 A;  1I5H W;  5E65 A;  3KCE A;  2DK7 A;  4A0T A;  2RE3 A;  2YSB A;  3MQH A;  4U85 A;  1WMV A;  2XP8 A;  5CQ2 A;  3FSC A;  1K9Q A;  1EG3 A;  2DMV A;  3ODK A;  3KAI A;  3M85 A;  2QRV A;  2ZQU A;  2XPB A;  2YAJ B;  5E62 A;  1WR7 A;  3M7N A;  2JX8 A;  3MQG A;  2XP9 A;  3LKX A;  3LE4 A;  3CNG A;  2E45 A;  2YSH A;  1O6W A;  2Y8N B;  2XP7 A;  2JV4 A;  1YW5 A;  2XP6 A;  2YSG A;  3MCB B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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