2DJYA

Solution structure of smurf2 ww3 domain-smad7 py peptide complex
Total Genus 3
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
3
sequence length
42
structure length
42
Chain Sequence
GPLGSGPLPPGWEIRNTATGRVYFVDHNNRTTQFTDPRLSAN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title An Expanded WW Domain Recognition Motif Revealed by the Interaction between Smad7 and the E3 Ubiquitin Ligase Smurf2.
pubmed doi rcsb
molecule tags Ligase/signaling protein
source organism Homo sapiens
molecule keywords Smad ubiquitination regulatory factor 2
total genus 3
structure length 42
sequence length 42
ec nomenclature ec 2.3.2.26: HECT-type E3 ubiquitin transferase.
pdb deposition date 2006-04-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00397 WW WW domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.70.10 Mainly Beta Single Sheet Ubiquitin Ligase Nedd4; Chain: W; Ubiquitin Ligase Nedd4; Chain: W; 2djyA01
1ZCNA 2LAJA 2XP5A 2DMVA 2Q5AA 3KADA 2XP8A 1PINA 1O6WA 4U86A 2DJYA 5CQ2A 2YSBA 2ZR5A 3KCEA 4QIBA 2ZAJA 2M3OW 3LE4A 1TK7A 3M85A 2ITKA 3KAHA 2M8IA 2ZQUA 2ZQSA 3TDBA 2XP3A 2DK1A 3KAGA 3OOBA 3KABA 1EG4A 5AHTA 3WH0A 1EG3A 2JMFA 2F21A 4E5RA 1I5HW 1K9RA 2DWVA 2YSHA 2L4JA 2EZ5W 2KXQA 2ZQVA 2YSIA 2E45A 2JX8A 2M8JA 2ZQTA 1NMVA 1YW5A 2XP4A 2ZR4A 4U85A 1K9QA 2XP7A 2JV4A 3ODKA 1WR7A 2XP9A 2DK7A 3CNGA 2XPAA 3L4HA 3NTPA 4U84A 1JMQA 3KAFA 2ZR6A 3TCZA 1WMVA 1F8AB 2XPBA 2XP6A 4REXA 3TC5A 2MDIA 2YSFA 3KAIA 2JXWA 2YSGA 2BA1A 3M7NA 2RE3A
chains in the Genus database with same CATH superfamily
1ZCNA 2LAJA 2XP5A 2DMVA 2Q5AA 3KADA 1TR8A 2XP8A 3MQHA 1PINA 1O6WA 4U86A 2DJYA 5U47A 5CQ2A 5E65A 2YSBA 2ZR5A 3KCEA 3LKXB 4QIBA 2ZAJA 2M3OW 3LE4A 1TK7A 3M85A 2YAJB 2ITKA 3KAHA 2M8IA 1FLCA 5E66A 2ZQUA 2ZQSA 3TDBA 2XP3A 2DK1A 3KAGA 3OOBA 3KABA 1EG4A 5AHTA 3WH0A 3MCBB 1EG3A 2JMFA 3LKXA 2F21A 4E5RA 1I5HW 3MQGA 2DWVA 1K9RA 2YSHA 2L4JA 2EZ5W 2KXQA 2ZQVA 4A0TA 2YSIA 2E45A 2Y8NB 2QRVA 5E64A 2JX8A 2M8JA 2OWOA 2ZQTA 1NMVA 1YW5A 2XP4A 1RP5A 2ZR4A 4U85A 1K9QA 2XP7A 2JV4A 5E62A 3ODKA 4GLXA 1WR7A 2XP9A 2DK7A 3CNGA 3L4HA 2XPAA 3NTPA 3FS8A 4U84A 1JMQA 3KAFA 2ZR6A 3TCZA 3FSCA 1WMVA 1F8AB 2XPBA 2XP6A 4REXA 3MCBA 2WADA 3PQHA 3TC5A 2MDIA 5E5WA 2YSFA 3KAIA 2JXWA 3FSBA 2YSGA 2BA1A 2WAEA 4A0UA 3M7NA 2RE3A
chains in the Genus database with same CATH topology
1ZCNA 2LAJA 2XP5A 2DMVA 2Q5AA 3KADA 1TR8A 2XP8A 3MQHA 1PINA 1O6WA 4U86A 2DJYA 5U47A 5CQ2A 5E65A 2YSBA 2ZR5A 3KCEA 3LKXB 4QIBA 2ZAJA 2M3OW 3LE4A 1TK7A 3M85A 2YAJB 2ITKA 3KAHA 2M8IA 1FLCA 5E66A 2ZQUA 2ZQSA 3TDBA 2XP3A 2DK1A 3KAGA 3OOBA 3KABA 1EG4A 5AHTA 3WH0A 3MCBB 1EG3A 2JMFA 3LKXA 2F21A 4E5RA 1I5HW 3MQGA 2DWVA 1K9RA 2YSHA 2L4JA 2EZ5W 2KXQA 2ZQVA 4A0TA 2YSIA 2E45A 2Y8NB 2QRVA 5E64A 2JX8A 2M8JA 2OWOA 2ZQTA 1NMVA 1YW5A 2XP4A 1RP5A 2ZR4A 4U85A 1K9QA 2XP7A 2JV4A 5E62A 3ODKA 4GLXA 1WR7A 2XP9A 2DK7A 3CNGA 3L4HA 2XPAA 3NTPA 3FS8A 4U84A 1JMQA 3KAFA 2ZR6A 3TCZA 3FSCA 1WMVA 1F8AB 2XPBA 2XP6A 4REXA 3MCBA 2WADA 3PQHA 3TC5A 2MDIA 5E5WA 2YSFA 3KAIA 2JXWA 3FSBA 2YSGA 2BA1A 2WAEA 4A0UA 3M7NA 2RE3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1ZCN A;  2LAJ A;  2XP5 A;  2DMV A;  2Q5A A;  3KAD A;  2XP8 A;  1PIN A;  1O6W A;  4U86 A;  2DJY A;  5CQ2 A;  2YSB A;  2ZR5 A;  3KCE A;  4QIB A;  2ZAJ A;  2M3O W;  3LE4 A;  1TK7 A;  3M85 A;  2ITK A;  3KAH A;  2M8I A;  2ZQU A;  2ZQS A;  3TDB A;  2XP3 A;  2DK1 A;  3KAG A;  3OOB A;  3KAB A;  1EG4 A;  5AHT A;  3WH0 A;  1EG3 A;  2JMF A;  2F21 A;  4E5R A;  1I5H W;  1K9R A;  2DWV A;  2YSH A;  2L4J A;  2EZ5 W;  2KXQ A;  2ZQV A;  2YSI A;  2E45 A;  2JX8 A;  2M8J A;  2ZQT A;  1NMV A;  1YW5 A;  2XP4 A;  2ZR4 A;  4U85 A;  1K9Q A;  2XP7 A;  2JV4 A;  3ODK A;  1WR7 A;  2XP9 A;  2DK7 A;  3CNG A;  2XPA A;  3L4H A;  3NTP A;  4U84 A;  1JMQ A;  3KAF A;  2ZR6 A;  3TCZ A;  1WMV A;  1F8A B;  2XPB A;  2XP6 A;  4REX A;  3TC5 A;  2MDI A;  2YSF A;  3KAI A;  2JXW A;  2YSG A;  2BA1 A;  3M7N A;  2RE3 A; 
#chains in the Genus database with same CATH topology
 1ZCN A;  2LAJ A;  2XP5 A;  2DMV A;  2Q5A A;  3KAD A;  1TR8 A;  2XP8 A;  3MQH A;  1PIN A;  1O6W A;  4U86 A;  2DJY A;  5U47 A;  5CQ2 A;  5E65 A;  2YSB A;  2ZR5 A;  3KCE A;  3LKX B;  4QIB A;  2ZAJ A;  2M3O W;  3LE4 A;  1TK7 A;  3M85 A;  2YAJ B;  2ITK A;  3KAH A;  2M8I A;  1FLC A;  5E66 A;  2ZQU A;  2ZQS A;  3TDB A;  2XP3 A;  2DK1 A;  3KAG A;  3OOB A;  3KAB A;  1EG4 A;  5AHT A;  3WH0 A;  3MCB B;  1EG3 A;  2JMF A;  3LKX A;  2F21 A;  4E5R A;  1I5H W;  3MQG A;  2DWV A;  1K9R A;  2YSH A;  2L4J A;  2EZ5 W;  2KXQ A;  2ZQV A;  4A0T A;  2YSI A;  2E45 A;  2Y8N B;  2QRV A;  5E64 A;  2JX8 A;  2M8J A;  2OWO A;  2ZQT A;  1NMV A;  1YW5 A;  2XP4 A;  1RP5 A;  2ZR4 A;  4U85 A;  1K9Q A;  2XP7 A;  2JV4 A;  5E62 A;  3ODK A;  4GLX A;  1WR7 A;  2XP9 A;  2DK7 A;  3CNG A;  3L4H A;  2XPA A;  3NTP A;  3FS8 A;  4U84 A;  1JMQ A;  3KAF A;  2ZR6 A;  3TCZ A;  3FSC A;  1WMV A;  1F8A B;  2XPB A;  2XP6 A;  4REX A;  3MCB A;  2WAD A;  3PQH A;  3TC5 A;  2MDI A;  5E5W A;  2YSF A;  3KAI A;  2JXW A;  3FSB A;  2YSG A;  2BA1 A;  2WAE A;  4A0U A;  3M7N A;  2RE3 A; 
#chains in the Genus database with same CATH homology
 1ZCN A;  2LAJ A;  2XP5 A;  2DMV A;  2Q5A A;  3KAD A;  1TR8 A;  2XP8 A;  3MQH A;  1PIN A;  1O6W A;  4U86 A;  2DJY A;  5U47 A;  5CQ2 A;  5E65 A;  2YSB A;  2ZR5 A;  3KCE A;  3LKX B;  4QIB A;  2ZAJ A;  2M3O W;  3LE4 A;  1TK7 A;  3M85 A;  2YAJ B;  2ITK A;  3KAH A;  2M8I A;  1FLC A;  5E66 A;  2ZQU A;  2ZQS A;  3TDB A;  2XP3 A;  2DK1 A;  3KAG A;  3OOB A;  3KAB A;  1EG4 A;  5AHT A;  3WH0 A;  3MCB B;  1EG3 A;  2JMF A;  3LKX A;  2F21 A;  4E5R A;  1I5H W;  3MQG A;  2DWV A;  1K9R A;  2YSH A;  2L4J A;  2EZ5 W;  2KXQ A;  2ZQV A;  4A0T A;  2YSI A;  2E45 A;  2Y8N B;  2QRV A;  5E64 A;  2JX8 A;  2M8J A;  2OWO A;  2ZQT A;  1NMV A;  1YW5 A;  2XP4 A;  1RP5 A;  2ZR4 A;  4U85 A;  1K9Q A;  2XP7 A;  2JV4 A;  5E62 A;  3ODK A;  4GLX A;  1WR7 A;  2XP9 A;  2DK7 A;  3CNG A;  3L4H A;  2XPA A;  3NTP A;  3FS8 A;  4U84 A;  1JMQ A;  3KAF A;  2ZR6 A;  3TCZ A;  3FSC A;  1WMV A;  1F8A B;  2XPB A;  2XP6 A;  4REX A;  3MCB A;  2WAD A;  3PQH A;  3TC5 A;  2MDI A;  5E5W A;  2YSF A;  3KAI A;  2JXW A;  3FSB A;  2YSG A;  2BA1 A;  2WAE A;  4A0U A;  3M7N A;  2RE3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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