2E45A

Solution structure of fe65 ww domain
Total Genus 2
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
2
sequence length
50
structure length
50
Chain Sequence
DSFWNPNAFETDSDLPAGWMRVQDTSGTYYWHIPTGTTQWEPPGRASPSQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structure of Fe65 WW domain
rcsb
molecule tags Protein binding
source organism Homo sapiens
molecule keywords Amyloid beta A4 precursor protein-binding family B member 1
total genus 2
structure length 50
sequence length 50
ec nomenclature
pdb deposition date 2006-12-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00397 WW WW domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.70.10 Mainly Beta Single Sheet Ubiquitin Ligase Nedd4; Chain: W; Ubiquitin Ligase Nedd4; Chain: W; 2e45A01
3M7NA 2DK7A 1F8AB 2YSFA 4QIBA 3KAFA 2MDIA 2KXQA 2XPAA 2DMVA 1O6WA 2ZQVA 2DWVA 2L4JA 1I5HW 1NMVA 3TDBA 2JMFA 2YSBA 2ZR5A 2XP6A 2Q5AA 4E5RA 2JX8A 4U84A 4U85A 2M3OW 1TK7A 2XP8A 1YW5A 3KAGA 1WR7A 2YSHA 3L4HA 1K9QA 2ZR6A 2XP3A 5AHTA 1EG4A 3M85A 2RE3A 2JV4A 2XP5A 3LE4A 3CNGA 2E45A 4REXA 3WH0A 2DK1A 1ZCNA 3NTPA 2XP4A 1K9RA 2M8IA 3KADA 2XP9A 2YSIA 1JMQA 2XPBA 3ODKA 1PINA 2ITKA 2M8JA 3TCZA 3KAHA 2ZQSA 3KCEA 3OOBA 2ZR4A 2ZQUA 2YSGA 5CQ2A 2ZQTA 2XP7A 2BA1A 3TC5A 2ZAJA 2DJYA 1EG3A 2LAJA 3KABA 4U86A 2F21A 2JXWA 3KAIA 1WMVA 2EZ5W
chains in the Genus database with same CATH superfamily
3M7NA 2DK7A 1F8AB 2YSFA 4QIBA 3KAFA 3FS8A 2MDIA 2KXQA 2XPAA 2DMVA 1O6WA 4GLXA 2ZQVA 2QRVA 2DWVA 2L4JA 1I5HW 1NMVA 3TDBA 1TR8A 2JMFA 2YSBA 2ZR5A 2XP6A 2Q5AA 4E5RA 2JX8A 4U84A 4U85A 2M3OW 1TK7A 2YAJB 2XP8A 5E62A 1YW5A 3KAGA 1WR7A 3MQGA 1RP5A 2YSHA 3L4HA 3MCBA 1K9QA 2ZR6A 2XP3A 5AHTA 1EG4A 4A0UA 3M85A 2RE3A 2JV4A 2XP5A 3LE4A 5E64A 3CNGA 2E45A 4REXA 3WH0A 2OWOA 2DK1A 1ZCNA 3MCBB 3NTPA 2XP4A 2WADA 1K9RA 2M8IA 5U47A 3FSCA 4A0TA 3KADA 5E66A 2XP9A 2YSIA 1FLCA 1JMQA 2XPBA 3ODKA 1PINA 5E5WA 3LKXA 2ITKA 2M8JA 2WAEA 3TCZA 3KAHA 2ZQSA 3KCEA 3OOBA 2ZR4A 2ZQUA 2YSGA 5CQ2A 2Y8NB 2ZQTA 3FSBA 2XP7A 2BA1A 3TC5A 2ZAJA 2DJYA 3MQHA 1EG3A 2LAJA 3KABA 5E65A 3LKXB 4U86A 2F21A 2JXWA 3KAIA 3PQHA 1WMVA 2EZ5W
chains in the Genus database with same CATH topology
3M7NA 2DK7A 1F8AB 2YSFA 4QIBA 3KAFA 3FS8A 2MDIA 2KXQA 2XPAA 2DMVA 1O6WA 4GLXA 2ZQVA 2QRVA 2DWVA 2L4JA 1I5HW 1NMVA 3TDBA 1TR8A 2JMFA 2YSBA 2ZR5A 2XP6A 2Q5AA 4E5RA 2JX8A 4U84A 4U85A 2M3OW 1TK7A 2YAJB 2XP8A 5E62A 1YW5A 3KAGA 1WR7A 3MQGA 1RP5A 2YSHA 3L4HA 3MCBA 1K9QA 2ZR6A 2XP3A 5AHTA 1EG4A 4A0UA 3M85A 2RE3A 2JV4A 2XP5A 3LE4A 5E64A 3CNGA 2E45A 4REXA 3WH0A 2OWOA 2DK1A 1ZCNA 3MCBB 3NTPA 2XP4A 2WADA 1K9RA 2M8IA 5U47A 3FSCA 4A0TA 3KADA 5E66A 2XP9A 2YSIA 1FLCA 1JMQA 2XPBA 3ODKA 1PINA 5E5WA 3LKXA 2ITKA 2M8JA 2WAEA 3TCZA 3KAHA 2ZQSA 3KCEA 3OOBA 2ZR4A 2ZQUA 2YSGA 5CQ2A 2Y8NB 2ZQTA 3FSBA 2XP7A 2BA1A 3TC5A 2ZAJA 2DJYA 3MQHA 1EG3A 2LAJA 3KABA 5E65A 3LKXB 4U86A 2F21A 2JXWA 3KAIA 3PQHA 1WMVA 2EZ5W
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3M7N A;  2DK7 A;  1F8A B;  2YSF A;  4QIB A;  3KAF A;  2MDI A;  2KXQ A;  2XPA A;  2DMV A;  1O6W A;  2ZQV A;  2DWV A;  2L4J A;  1I5H W;  1NMV A;  3TDB A;  2JMF A;  2YSB A;  2ZR5 A;  2XP6 A;  2Q5A A;  4E5R A;  2JX8 A;  4U84 A;  4U85 A;  2M3O W;  1TK7 A;  2XP8 A;  1YW5 A;  3KAG A;  1WR7 A;  2YSH A;  3L4H A;  1K9Q A;  2ZR6 A;  2XP3 A;  5AHT A;  1EG4 A;  3M85 A;  2RE3 A;  2JV4 A;  2XP5 A;  3LE4 A;  3CNG A;  2E45 A;  4REX A;  3WH0 A;  2DK1 A;  1ZCN A;  3NTP A;  2XP4 A;  1K9R A;  2M8I A;  3KAD A;  2XP9 A;  2YSI A;  1JMQ A;  2XPB A;  3ODK A;  1PIN A;  2ITK A;  2M8J A;  3TCZ A;  3KAH A;  2ZQS A;  3KCE A;  3OOB A;  2ZR4 A;  2ZQU A;  2YSG A;  5CQ2 A;  2ZQT A;  2XP7 A;  2BA1 A;  3TC5 A;  2ZAJ A;  2DJY A;  1EG3 A;  2LAJ A;  3KAB A;  4U86 A;  2F21 A;  2JXW A;  3KAI A;  1WMV A;  2EZ5 W; 
#chains in the Genus database with same CATH topology
 3M7N A;  2DK7 A;  1F8A B;  2YSF A;  4QIB A;  3KAF A;  3FS8 A;  2MDI A;  2KXQ A;  2XPA A;  2DMV A;  1O6W A;  4GLX A;  2ZQV A;  2QRV A;  2DWV A;  2L4J A;  1I5H W;  1NMV A;  3TDB A;  1TR8 A;  2JMF A;  2YSB A;  2ZR5 A;  2XP6 A;  2Q5A A;  4E5R A;  2JX8 A;  4U84 A;  4U85 A;  2M3O W;  1TK7 A;  2YAJ B;  2XP8 A;  5E62 A;  1YW5 A;  3KAG A;  1WR7 A;  3MQG A;  1RP5 A;  2YSH A;  3L4H A;  3MCB A;  1K9Q A;  2ZR6 A;  2XP3 A;  5AHT A;  1EG4 A;  4A0U A;  3M85 A;  2RE3 A;  2JV4 A;  2XP5 A;  3LE4 A;  5E64 A;  3CNG A;  2E45 A;  4REX A;  3WH0 A;  2OWO A;  2DK1 A;  1ZCN A;  3MCB B;  3NTP A;  2XP4 A;  2WAD A;  1K9R A;  2M8I A;  5U47 A;  3FSC A;  4A0T A;  3KAD A;  5E66 A;  2XP9 A;  2YSI A;  1FLC A;  1JMQ A;  2XPB A;  3ODK A;  1PIN A;  5E5W A;  3LKX A;  2ITK A;  2M8J A;  2WAE A;  3TCZ A;  3KAH A;  2ZQS A;  3KCE A;  3OOB A;  2ZR4 A;  2ZQU A;  2YSG A;  5CQ2 A;  2Y8N B;  2ZQT A;  3FSB A;  2XP7 A;  2BA1 A;  3TC5 A;  2ZAJ A;  2DJY A;  3MQH A;  1EG3 A;  2LAJ A;  3KAB A;  5E65 A;  3LKX B;  4U86 A;  2F21 A;  2JXW A;  3KAI A;  3PQH A;  1WMV A;  2EZ5 W; 
#chains in the Genus database with same CATH homology
 3M7N A;  2DK7 A;  1F8A B;  2YSF A;  4QIB A;  3KAF A;  3FS8 A;  2MDI A;  2KXQ A;  2XPA A;  2DMV A;  1O6W A;  4GLX A;  2ZQV A;  2QRV A;  2DWV A;  2L4J A;  1I5H W;  1NMV A;  3TDB A;  1TR8 A;  2JMF A;  2YSB A;  2ZR5 A;  2XP6 A;  2Q5A A;  4E5R A;  2JX8 A;  4U84 A;  4U85 A;  2M3O W;  1TK7 A;  2YAJ B;  2XP8 A;  5E62 A;  1YW5 A;  3KAG A;  1WR7 A;  3MQG A;  1RP5 A;  2YSH A;  3L4H A;  3MCB A;  1K9Q A;  2ZR6 A;  2XP3 A;  5AHT A;  1EG4 A;  4A0U A;  3M85 A;  2RE3 A;  2JV4 A;  2XP5 A;  3LE4 A;  5E64 A;  3CNG A;  2E45 A;  4REX A;  3WH0 A;  2OWO A;  2DK1 A;  1ZCN A;  3MCB B;  3NTP A;  2XP4 A;  2WAD A;  1K9R A;  2M8I A;  5U47 A;  3FSC A;  4A0T A;  3KAD A;  5E66 A;  2XP9 A;  2YSI A;  1FLC A;  1JMQ A;  2XPB A;  3ODK A;  1PIN A;  5E5W A;  3LKX A;  2ITK A;  2M8J A;  2WAE A;  3TCZ A;  3KAH A;  2ZQS A;  3KCE A;  3OOB A;  2ZR4 A;  2ZQU A;  2YSG A;  5CQ2 A;  2Y8N B;  2ZQT A;  3FSB A;  2XP7 A;  2BA1 A;  3TC5 A;  2ZAJ A;  2DJY A;  3MQH A;  1EG3 A;  2LAJ A;  3KAB A;  5E65 A;  3LKX B;  4U86 A;  2F21 A;  2JXW A;  3KAI A;  3PQH A;  1WMV A;  2EZ5 W; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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