2EZ5W

Solution structure of the dnedd4 ww3* domain- comm lpsy peptide complex
Total Genus 5
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
5
sequence length
46
structure length
46
Chain Sequence
GPLGSGEEEPLPPRWSMQVAPNGRTFFIDHASRRTTWIDPRNGRAS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Determinants for High-Affinity Binding in a Nedd4 WW3(*) Domain-Comm PY Motif Complex
pubmed doi rcsb
molecule tags Signalling protein,ligase
source organism Drosophila melanogaster
molecule keywords E3 ubiquitin-protein ligase NEDD4
total genus 5
structure length 46
sequence length 46
ec nomenclature ec 2.3.2.26: HECT-type E3 ubiquitin transferase.
pdb deposition date 2005-11-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
W PF00397 WW WW domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.70.10 Mainly Beta Single Sheet Ubiquitin Ligase Nedd4; Chain: W; Ubiquitin Ligase Nedd4; Chain: W; 2ez5W01
3CNGA 3KAIA 2ITKA 2Q5AA 2JXWA 3NTPA 2XP7A 2ZQVA 2YSIA 2JMFA 2M8IA 1NMVA 2DJYA 2JV4A 4U86A 1TK7A 2ZR4A 3M7NA 2ZQSA 2YSBA 2F21A 2XP6A 2M3OW 2DK1A 3OOBA 2XPAA 1O6WA 1PINA 1ZCNA 3LE4A 1WR7A 2XP3A 3KAHA 1JMQA 3KAGA 2XP5A 4U84A 5AHTA 3TDBA 2DWVA 2ZAJA 3M85A 2BA1A 2YSHA 2YSGA 1K9QA 3KADA 2YSFA 1EG4A 2DMVA 2JX8A 2LAJA 2ZR5A 2ZQTA 2EZ5W 4REXA 3ODKA 4U85A 1K9RA 2M8JA 2KXQA 1WMVA 4QIBA 3TCZA 2XPBA 4E5RA 1F8AB 3KAFA 3KABA 2XP9A 2MDIA 2XP8A 3L4HA 3KCEA 2ZR6A 2XP4A 1YW5A 1EG3A 5CQ2A 3TC5A 2ZQUA 2RE3A 1I5HW 2L4JA 2DK7A 2E45A 3WH0A
chains in the Genus database with same CATH superfamily
1RP5A 3CNGA 3KAIA 2ITKA 2Q5AA 2JXWA 3NTPA 2XP7A 2ZQVA 2YSIA 2JMFA 2M8IA 1NMVA 2DJYA 2JV4A 2QRVA 1TK7A 4U86A 2ZR4A 3M7NA 2ZQSA 2Y8NB 2YSBA 2F21A 2XP6A 2M3OW 3LKXB 2DK1A 3OOBA 2XPAA 2YAJB 1O6WA 1PINA 3FS8A 1ZCNA 3LE4A 1WR7A 2XP3A 3KAHA 1JMQA 3KAGA 2XP5A 4U84A 5E62A 5AHTA 3TDBA 2DWVA 4A0UA 2ZAJA 3M85A 4GLXA 2BA1A 2YSHA 2YSGA 5E65A 1K9QA 3MCBA 3KADA 3MQHA 2YSFA 1EG4A 2DMVA 2JX8A 2WADA 1TR8A 1FLCA 4A0TA 2LAJA 2ZR5A 2ZQTA 2EZ5W 4REXA 3ODKA 4U85A 5E66A 1K9RA 2M8JA 2KXQA 1WMVA 3LKXA 4QIBA 3TCZA 3MCBB 5E64A 2XPBA 4E5RA 1F8AB 3KAFA 3KABA 2OWOA 2XP9A 2MDIA 2XP8A 3L4HA 3KCEA 2ZR6A 2XP4A 1YW5A 5U47A 5E5WA 3FSCA 3PQHA 3FSBA 1EG3A 2WAEA 5CQ2A 3TC5A 2ZQUA 2RE3A 3MQGA 1I5HW 2L4JA 2DK7A 2E45A 3WH0A
chains in the Genus database with same CATH topology
1RP5A 3CNGA 3KAIA 2ITKA 2Q5AA 2JXWA 3NTPA 2XP7A 2ZQVA 2YSIA 2JMFA 2M8IA 1NMVA 2DJYA 2JV4A 2QRVA 1TK7A 4U86A 2ZR4A 3M7NA 2ZQSA 2Y8NB 2YSBA 2F21A 2XP6A 2M3OW 3LKXB 2DK1A 3OOBA 2XPAA 2YAJB 1O6WA 1PINA 3FS8A 1ZCNA 3LE4A 1WR7A 2XP3A 3KAHA 1JMQA 3KAGA 2XP5A 4U84A 5E62A 5AHTA 3TDBA 2DWVA 4A0UA 2ZAJA 3M85A 4GLXA 2BA1A 2YSHA 2YSGA 5E65A 1K9QA 3MCBA 3KADA 3MQHA 2YSFA 1EG4A 2DMVA 2JX8A 2WADA 1TR8A 1FLCA 4A0TA 2LAJA 2ZR5A 2ZQTA 2EZ5W 4REXA 3ODKA 4U85A 5E66A 1K9RA 2M8JA 2KXQA 1WMVA 3LKXA 4QIBA 3TCZA 3MCBB 5E64A 2XPBA 4E5RA 1F8AB 3KAFA 3KABA 2OWOA 2XP9A 2MDIA 2XP8A 3L4HA 3KCEA 2ZR6A 2XP4A 1YW5A 5U47A 5E5WA 3FSCA 3PQHA 3FSBA 1EG3A 2WAEA 5CQ2A 3TC5A 2ZQUA 2RE3A 3MQGA 1I5HW 2L4JA 2DK7A 2E45A 3WH0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CNG A;  3KAI A;  2ITK A;  2Q5A A;  2JXW A;  3NTP A;  2XP7 A;  2ZQV A;  2YSI A;  2JMF A;  2M8I A;  1NMV A;  2DJY A;  2JV4 A;  4U86 A;  1TK7 A;  2ZR4 A;  3M7N A;  2ZQS A;  2YSB A;  2F21 A;  2XP6 A;  2M3O W;  2DK1 A;  3OOB A;  2XPA A;  1O6W A;  1PIN A;  1ZCN A;  3LE4 A;  1WR7 A;  2XP3 A;  3KAH A;  1JMQ A;  3KAG A;  2XP5 A;  4U84 A;  5AHT A;  3TDB A;  2DWV A;  2ZAJ A;  3M85 A;  2BA1 A;  2YSH A;  2YSG A;  1K9Q A;  3KAD A;  2YSF A;  1EG4 A;  2DMV A;  2JX8 A;  2LAJ A;  2ZR5 A;  2ZQT A;  2EZ5 W;  4REX A;  3ODK A;  4U85 A;  1K9R A;  2M8J A;  2KXQ A;  1WMV A;  4QIB A;  3TCZ A;  2XPB A;  4E5R A;  1F8A B;  3KAF A;  3KAB A;  2XP9 A;  2MDI A;  2XP8 A;  3L4H A;  3KCE A;  2ZR6 A;  2XP4 A;  1YW5 A;  1EG3 A;  5CQ2 A;  3TC5 A;  2ZQU A;  2RE3 A;  1I5H W;  2L4J A;  2DK7 A;  2E45 A;  3WH0 A; 
#chains in the Genus database with same CATH topology
 1RP5 A;  3CNG A;  3KAI A;  2ITK A;  2Q5A A;  2JXW A;  3NTP A;  2XP7 A;  2ZQV A;  2YSI A;  2JMF A;  2M8I A;  1NMV A;  2DJY A;  2JV4 A;  2QRV A;  1TK7 A;  4U86 A;  2ZR4 A;  3M7N A;  2ZQS A;  2Y8N B;  2YSB A;  2F21 A;  2XP6 A;  2M3O W;  3LKX B;  2DK1 A;  3OOB A;  2XPA A;  2YAJ B;  1O6W A;  1PIN A;  3FS8 A;  1ZCN A;  3LE4 A;  1WR7 A;  2XP3 A;  3KAH A;  1JMQ A;  3KAG A;  2XP5 A;  4U84 A;  5E62 A;  5AHT A;  3TDB A;  2DWV A;  4A0U A;  2ZAJ A;  3M85 A;  4GLX A;  2BA1 A;  2YSH A;  2YSG A;  5E65 A;  1K9Q A;  3MCB A;  3KAD A;  3MQH A;  2YSF A;  1EG4 A;  2DMV A;  2JX8 A;  2WAD A;  1TR8 A;  1FLC A;  4A0T A;  2LAJ A;  2ZR5 A;  2ZQT A;  2EZ5 W;  4REX A;  3ODK A;  4U85 A;  5E66 A;  1K9R A;  2M8J A;  2KXQ A;  1WMV A;  3LKX A;  4QIB A;  3TCZ A;  3MCB B;  5E64 A;  2XPB A;  4E5R A;  1F8A B;  3KAF A;  3KAB A;  2OWO A;  2XP9 A;  2MDI A;  2XP8 A;  3L4H A;  3KCE A;  2ZR6 A;  2XP4 A;  1YW5 A;  5U47 A;  5E5W A;  3FSC A;  3PQH A;  3FSB A;  1EG3 A;  2WAE A;  5CQ2 A;  3TC5 A;  2ZQU A;  2RE3 A;  3MQG A;  1I5H W;  2L4J A;  2DK7 A;  2E45 A;  3WH0 A; 
#chains in the Genus database with same CATH homology
 1RP5 A;  3CNG A;  3KAI A;  2ITK A;  2Q5A A;  2JXW A;  3NTP A;  2XP7 A;  2ZQV A;  2YSI A;  2JMF A;  2M8I A;  1NMV A;  2DJY A;  2JV4 A;  2QRV A;  1TK7 A;  4U86 A;  2ZR4 A;  3M7N A;  2ZQS A;  2Y8N B;  2YSB A;  2F21 A;  2XP6 A;  2M3O W;  3LKX B;  2DK1 A;  3OOB A;  2XPA A;  2YAJ B;  1O6W A;  1PIN A;  3FS8 A;  1ZCN A;  3LE4 A;  1WR7 A;  2XP3 A;  3KAH A;  1JMQ A;  3KAG A;  2XP5 A;  4U84 A;  5E62 A;  5AHT A;  3TDB A;  2DWV A;  4A0U A;  2ZAJ A;  3M85 A;  4GLX A;  2BA1 A;  2YSH A;  2YSG A;  5E65 A;  1K9Q A;  3MCB A;  3KAD A;  3MQH A;  2YSF A;  1EG4 A;  2DMV A;  2JX8 A;  2WAD A;  1TR8 A;  1FLC A;  4A0T A;  2LAJ A;  2ZR5 A;  2ZQT A;  2EZ5 W;  4REX A;  3ODK A;  4U85 A;  5E66 A;  1K9R A;  2M8J A;  2KXQ A;  1WMV A;  3LKX A;  4QIB A;  3TCZ A;  3MCB B;  5E64 A;  2XPB A;  4E5R A;  1F8A B;  3KAF A;  3KAB A;  2OWO A;  2XP9 A;  2MDI A;  2XP8 A;  3L4H A;  3KCE A;  2ZR6 A;  2XP4 A;  1YW5 A;  5U47 A;  5E5W A;  3FSC A;  3PQH A;  3FSB A;  1EG3 A;  2WAE A;  5CQ2 A;  3TC5 A;  2ZQU A;  2RE3 A;  3MQG A;  1I5H W;  2L4J A;  2DK7 A;  2E45 A;  3WH0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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