2M3OW

Structure and dynamics of a human nedd4 ww domain-enac complex
Total Genus 4
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
4
sequence length
43
structure length
43
Chain Sequence
GSMEQGFLPKGWEVRHAPNGRPFFIDHNTKTTTWEDPRLKIPA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structure and dynamics of human Nedd4-1 WW3 in complex with the alpha ENaC PY motif.
pubmed doi rcsb
molecule tags Peptide binding protein/protein binding
source organism Homo sapiens
molecule keywords E3 ubiquitin-protein ligase NEDD4
total genus 4
structure length 43
sequence length 43
ec nomenclature ec 2.3.2.26: HECT-type E3 ubiquitin transferase.
pdb deposition date 2013-01-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
W PF00397 WW WW domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.70.10 Mainly Beta Single Sheet Ubiquitin Ligase Nedd4; Chain: W; Ubiquitin Ligase Nedd4; Chain: W; 2m3oW01
2JX8A 3KAIA 3KCEA 2Q5AA 3CNGA 3ODKA 1K9QA 3M85A 2JV4A 2M8IA 2ZR4A 2DJYA 2E45A 2YSIA 3OOBA 1EG4A 3KAHA 1ZCNA 4U86A 2KXQA 2DWVA 1NMVA 1TK7A 3NTPA 3TDBA 4QIBA 2DMVA 2MDIA 5CQ2A 1WMVA 3LE4A 3TC5A 1EG3A 4REXA 2ZR5A 2ZQTA 2M8JA 2XP6A 2ZQVA 2XP3A 2L4JA 1WR7A 2XP8A 2XP4A 2ZQUA 1K9RA 3KAFA 2XPBA 2XP9A 3KAGA 2XPAA 1YW5A 2ZAJA 4U84A 3TCZA 2LAJA 2RE3A 2YSHA 3KADA 5AHTA 3M7NA 1O6WA 2ZR6A 1F8AB 1I5HW 4U85A 2YSBA 3WH0A 2JMFA 2XP5A 1PINA 2M3OW 4E5RA 2BA1A 2XP7A 2ITKA 2ZQSA 2DK7A 2F21A 3L4HA 2YSGA 2EZ5W 1JMQA 2DK1A 2JXWA 3KABA 2YSFA
chains in the Genus database with same CATH superfamily
4A0UA 2JX8A 3KAIA 1TR8A 3KCEA 2Q5AA 3CNGA 3ODKA 1K9QA 1RP5A 3M85A 2JV4A 2M8IA 2ZR4A 2DJYA 2Y8NB 2E45A 2YSIA 3MQHA 1EG4A 3OOBA 3KAHA 1FLCA 1ZCNA 4U86A 2KXQA 3LKXB 2DWVA 2QRVA 1NMVA 1TK7A 3MQGA 3NTPA 3TDBA 4QIBA 2DMVA 2MDIA 5CQ2A 2OWOA 3LKXA 1WMVA 3LE4A 3TC5A 1EG3A 3PQHA 4REXA 4GLXA 2ZR5A 2ZQTA 2M8JA 2XP6A 2ZQVA 5E5WA 2XP3A 5E64A 2L4JA 3FSCA 1WR7A 5U47A 2XP8A 2XP4A 2ZQUA 1K9RA 3KAFA 2XPBA 2XP9A 3KAGA 2YAJB 5E66A 2XPAA 1YW5A 2ZAJA 4U84A 3TCZA 2LAJA 2RE3A 2YSHA 3KADA 5AHTA 3M7NA 1O6WA 2ZR6A 5E62A 1F8AB 1I5HW 2YSBA 2WADA 4U85A 3WH0A 2JMFA 2XP5A 1PINA 2M3OW 4E5RA 2BA1A 2XP7A 2WAEA 2ITKA 2ZQSA 3MCBB 2DK7A 2F21A 3L4HA 4A0TA 2YSGA 3FS8A 2EZ5W 5E65A 1JMQA 2DK1A 2JXWA 3FSBA 3KABA 2YSFA 3MCBA
chains in the Genus database with same CATH topology
4A0UA 2JX8A 3KAIA 1TR8A 3KCEA 2Q5AA 3CNGA 3ODKA 1K9QA 1RP5A 3M85A 2JV4A 2M8IA 2ZR4A 2DJYA 2Y8NB 2E45A 2YSIA 3MQHA 1EG4A 3OOBA 3KAHA 1FLCA 1ZCNA 4U86A 2KXQA 3LKXB 2DWVA 2QRVA 1NMVA 1TK7A 3MQGA 3NTPA 3TDBA 4QIBA 2DMVA 2MDIA 5CQ2A 2OWOA 3LKXA 1WMVA 3LE4A 3TC5A 1EG3A 3PQHA 4REXA 4GLXA 2ZR5A 2ZQTA 2M8JA 2XP6A 2ZQVA 5E5WA 2XP3A 5E64A 2L4JA 3FSCA 1WR7A 5U47A 2XP8A 2XP4A 2ZQUA 1K9RA 3KAFA 2XPBA 2XP9A 3KAGA 2YAJB 5E66A 2XPAA 1YW5A 2ZAJA 4U84A 3TCZA 2LAJA 2RE3A 2YSHA 3KADA 5AHTA 3M7NA 1O6WA 2ZR6A 5E62A 1F8AB 1I5HW 2YSBA 2WADA 4U85A 3WH0A 2JMFA 2XP5A 1PINA 2M3OW 4E5RA 2BA1A 2XP7A 2WAEA 2ITKA 2ZQSA 3MCBB 2DK7A 2F21A 3L4HA 4A0TA 2YSGA 3FS8A 2EZ5W 5E65A 1JMQA 2DK1A 2JXWA 3FSBA 3KABA 2YSFA 3MCBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2JX8 A;  3KAI A;  3KCE A;  2Q5A A;  3CNG A;  3ODK A;  1K9Q A;  3M85 A;  2JV4 A;  2M8I A;  2ZR4 A;  2DJY A;  2E45 A;  2YSI A;  3OOB A;  1EG4 A;  3KAH A;  1ZCN A;  4U86 A;  2KXQ A;  2DWV A;  1NMV A;  1TK7 A;  3NTP A;  3TDB A;  4QIB A;  2DMV A;  2MDI A;  5CQ2 A;  1WMV A;  3LE4 A;  3TC5 A;  1EG3 A;  4REX A;  2ZR5 A;  2ZQT A;  2M8J A;  2XP6 A;  2ZQV A;  2XP3 A;  2L4J A;  1WR7 A;  2XP8 A;  2XP4 A;  2ZQU A;  1K9R A;  3KAF A;  2XPB A;  2XP9 A;  3KAG A;  2XPA A;  1YW5 A;  2ZAJ A;  4U84 A;  3TCZ A;  2LAJ A;  2RE3 A;  2YSH A;  3KAD A;  5AHT A;  3M7N A;  1O6W A;  2ZR6 A;  1F8A B;  1I5H W;  4U85 A;  2YSB A;  3WH0 A;  2JMF A;  2XP5 A;  1PIN A;  2M3O W;  4E5R A;  2BA1 A;  2XP7 A;  2ITK A;  2ZQS A;  2DK7 A;  2F21 A;  3L4H A;  2YSG A;  2EZ5 W;  1JMQ A;  2DK1 A;  2JXW A;  3KAB A;  2YSF A; 
#chains in the Genus database with same CATH topology
 4A0U A;  2JX8 A;  3KAI A;  1TR8 A;  3KCE A;  2Q5A A;  3CNG A;  3ODK A;  1K9Q A;  1RP5 A;  3M85 A;  2JV4 A;  2M8I A;  2ZR4 A;  2DJY A;  2Y8N B;  2E45 A;  2YSI A;  3MQH A;  1EG4 A;  3OOB A;  3KAH A;  1FLC A;  1ZCN A;  4U86 A;  2KXQ A;  3LKX B;  2DWV A;  2QRV A;  1NMV A;  1TK7 A;  3MQG A;  3NTP A;  3TDB A;  4QIB A;  2DMV A;  2MDI A;  5CQ2 A;  2OWO A;  3LKX A;  1WMV A;  3LE4 A;  3TC5 A;  1EG3 A;  3PQH A;  4REX A;  4GLX A;  2ZR5 A;  2ZQT A;  2M8J A;  2XP6 A;  2ZQV A;  5E5W A;  2XP3 A;  5E64 A;  2L4J A;  3FSC A;  1WR7 A;  5U47 A;  2XP8 A;  2XP4 A;  2ZQU A;  1K9R A;  3KAF A;  2XPB A;  2XP9 A;  3KAG A;  2YAJ B;  5E66 A;  2XPA A;  1YW5 A;  2ZAJ A;  4U84 A;  3TCZ A;  2LAJ A;  2RE3 A;  2YSH A;  3KAD A;  5AHT A;  3M7N A;  1O6W A;  2ZR6 A;  5E62 A;  1F8A B;  1I5H W;  2YSB A;  2WAD A;  4U85 A;  3WH0 A;  2JMF A;  2XP5 A;  1PIN A;  2M3O W;  4E5R A;  2BA1 A;  2XP7 A;  2WAE A;  2ITK A;  2ZQS A;  3MCB B;  2DK7 A;  2F21 A;  3L4H A;  4A0T A;  2YSG A;  3FS8 A;  2EZ5 W;  5E65 A;  1JMQ A;  2DK1 A;  2JXW A;  3FSB A;  3KAB A;  2YSF A;  3MCB A; 
#chains in the Genus database with same CATH homology
 4A0U A;  2JX8 A;  3KAI A;  1TR8 A;  3KCE A;  2Q5A A;  3CNG A;  3ODK A;  1K9Q A;  1RP5 A;  3M85 A;  2JV4 A;  2M8I A;  2ZR4 A;  2DJY A;  2Y8N B;  2E45 A;  2YSI A;  3MQH A;  1EG4 A;  3OOB A;  3KAH A;  1FLC A;  1ZCN A;  4U86 A;  2KXQ A;  3LKX B;  2DWV A;  2QRV A;  1NMV A;  1TK7 A;  3MQG A;  3NTP A;  3TDB A;  4QIB A;  2DMV A;  2MDI A;  5CQ2 A;  2OWO A;  3LKX A;  1WMV A;  3LE4 A;  3TC5 A;  1EG3 A;  3PQH A;  4REX A;  4GLX A;  2ZR5 A;  2ZQT A;  2M8J A;  2XP6 A;  2ZQV A;  5E5W A;  2XP3 A;  5E64 A;  2L4J A;  3FSC A;  1WR7 A;  5U47 A;  2XP8 A;  2XP4 A;  2ZQU A;  1K9R A;  3KAF A;  2XPB A;  2XP9 A;  3KAG A;  2YAJ B;  5E66 A;  2XPA A;  1YW5 A;  2ZAJ A;  4U84 A;  3TCZ A;  2LAJ A;  2RE3 A;  2YSH A;  3KAD A;  5AHT A;  3M7N A;  1O6W A;  2ZR6 A;  5E62 A;  1F8A B;  1I5H W;  2YSB A;  2WAD A;  4U85 A;  3WH0 A;  2JMF A;  2XP5 A;  1PIN A;  2M3O W;  4E5R A;  2BA1 A;  2XP7 A;  2WAE A;  2ITK A;  2ZQS A;  3MCB B;  2DK7 A;  2F21 A;  3L4H A;  4A0T A;  2YSG A;  3FS8 A;  2EZ5 W;  5E65 A;  1JMQ A;  2DK1 A;  2JXW A;  3FSB A;  3KAB A;  2YSF A;  3MCB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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