3LE4A

Crystal structure of the dgcr8 dimerization domain
Total Genus 3
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
3
sequence length
55
structure length
55
Chain Sequence
PPTEPLPDGWIMTFHNSGVPVYLHRESRVVTWSRPYFLGTGSIRKHDPPLSSIPC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structure of the dimerization domain of DiGeorge Critical Region 8
pubmed doi rcsb
molecule tags Nuclear protein
source organism Homo sapiens
molecule keywords Microprocessor complex subunit DGCR8
total genus 3
structure length 55
sequence length 55
ec nomenclature
pdb deposition date 2010-01-14
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.70.10 Mainly Beta Single Sheet Ubiquitin Ligase Nedd4; Chain: W; Ubiquitin Ligase Nedd4; Chain: W; 3le4A00
3KAFA 2ZQVA 1YW5A 2XPBA 2ZR4A 1O6WA 2XP7A 4REXA 2MDIA 2JXWA 2XP4A 1K9RA 1EG3A 2Q5AA 2JX8A 2JV4A 1JMQA 2YSIA 2ZR5A 2YSHA 2XP9A 3KCEA 2ZR6A 3KADA 3KAGA 2ITKA 3KAHA 4U86A 2BA1A 3LE4A 3NTPA 1EG4A 2ZQSA 2XP3A 4E5RA 2ZQTA 1F8AB 2LAJA 2DJYA 2L4JA 1PINA 2DK7A 3TDBA 2M3OW 2M8JA 2YSGA 4QIBA 2E45A 2DWVA 3KAIA 5AHTA 1ZCNA 3M7NA 3L4HA 3KABA 1WMVA 3CNGA 2XP8A 2F21A 5CQ2A 4U84A 2XP5A 1WR7A 2KXQA 2M8IA 1K9QA 2YSBA 2ZAJA 2JMFA 4U85A 1NMVA 3TC5A 2XP6A 2ZQUA 2EZ5W 2DMVA 3M85A 2XPAA 3ODKA 3TCZA 2RE3A 1I5HW 2DK1A 2YSFA 3OOBA 3WH0A 1TK7A
chains in the Genus database with same CATH superfamily
3KAFA 2QRVA 2ZQVA 1YW5A 2XPBA 4GLXA 2ZR4A 1O6WA 2WADA 2XP7A 4REXA 5E65A 2MDIA 2JXWA 2XP4A 3FSBA 1K9RA 1RP5A 1EG3A 2Q5AA 2JX8A 2JV4A 5E62A 5U47A 1JMQA 3MQHA 2YSIA 2ZR5A 2YSHA 2Y8NB 2XP9A 3KCEA 2ZR6A 3KADA 3KAGA 2ITKA 3KAHA 4U86A 2BA1A 3LE4A 3NTPA 1EG4A 2ZQSA 2XP3A 4E5RA 2ZQTA 2YAJB 1F8AB 2LAJA 2DJYA 2L4JA 1PINA 2OWOA 2DK7A 5E5WA 3TDBA 2M3OW 2M8JA 2YSGA 4QIBA 4A0UA 2E45A 1TR8A 2DWVA 3KAIA 4A0TA 5AHTA 3FS8A 1ZCNA 3M7NA 3L4HA 3KABA 1WMVA 3CNGA 2XP8A 2F21A 5CQ2A 4U84A 2XP5A 3PQHA 3MQGA 3MCBB 1WR7A 2KXQA 2M8IA 1K9QA 2YSBA 2ZAJA 2JMFA 4U85A 1NMVA 3TC5A 2XP6A 2ZQUA 3LKXB 5E64A 2EZ5W 2DMVA 3M85A 2XPAA 3ODKA 3TCZA 1FLCA 2RE3A 3MCBA 1I5HW 2DK1A 3FSCA 3LKXA 2YSFA 3OOBA 2WAEA 3WH0A 5E66A 1TK7A
chains in the Genus database with same CATH topology
3KAFA 2QRVA 2ZQVA 1YW5A 2XPBA 4GLXA 2ZR4A 1O6WA 2WADA 2XP7A 4REXA 5E65A 2MDIA 2JXWA 2XP4A 3FSBA 1K9RA 1RP5A 1EG3A 2Q5AA 2JX8A 2JV4A 5E62A 5U47A 1JMQA 3MQHA 2YSIA 2ZR5A 2YSHA 2Y8NB 2XP9A 3KCEA 2ZR6A 3KADA 3KAGA 2ITKA 3KAHA 4U86A 2BA1A 3LE4A 3NTPA 1EG4A 2ZQSA 2XP3A 4E5RA 2ZQTA 2YAJB 1F8AB 2LAJA 2DJYA 2L4JA 1PINA 2OWOA 2DK7A 5E5WA 3TDBA 2M3OW 2M8JA 2YSGA 4QIBA 4A0UA 2E45A 1TR8A 2DWVA 3KAIA 4A0TA 5AHTA 3FS8A 1ZCNA 3M7NA 3L4HA 3KABA 1WMVA 3CNGA 2XP8A 2F21A 5CQ2A 4U84A 2XP5A 3PQHA 3MQGA 3MCBB 1WR7A 2KXQA 2M8IA 1K9QA 2YSBA 2ZAJA 2JMFA 4U85A 1NMVA 3TC5A 2XP6A 2ZQUA 3LKXB 5E64A 2EZ5W 2DMVA 3M85A 2XPAA 3ODKA 3TCZA 1FLCA 2RE3A 3MCBA 1I5HW 2DK1A 3FSCA 3LKXA 2YSFA 3OOBA 2WAEA 3WH0A 5E66A 1TK7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3KAF A;  2ZQV A;  1YW5 A;  2XPB A;  2ZR4 A;  1O6W A;  2XP7 A;  4REX A;  2MDI A;  2JXW A;  2XP4 A;  1K9R A;  1EG3 A;  2Q5A A;  2JX8 A;  2JV4 A;  1JMQ A;  2YSI A;  2ZR5 A;  2YSH A;  2XP9 A;  3KCE A;  2ZR6 A;  3KAD A;  3KAG A;  2ITK A;  3KAH A;  4U86 A;  2BA1 A;  3LE4 A;  3NTP A;  1EG4 A;  2ZQS A;  2XP3 A;  4E5R A;  2ZQT A;  1F8A B;  2LAJ A;  2DJY A;  2L4J A;  1PIN A;  2DK7 A;  3TDB A;  2M3O W;  2M8J A;  2YSG A;  4QIB A;  2E45 A;  2DWV A;  3KAI A;  5AHT A;  1ZCN A;  3M7N A;  3L4H A;  3KAB A;  1WMV A;  3CNG A;  2XP8 A;  2F21 A;  5CQ2 A;  4U84 A;  2XP5 A;  1WR7 A;  2KXQ A;  2M8I A;  1K9Q A;  2YSB A;  2ZAJ A;  2JMF A;  4U85 A;  1NMV A;  3TC5 A;  2XP6 A;  2ZQU A;  2EZ5 W;  2DMV A;  3M85 A;  2XPA A;  3ODK A;  3TCZ A;  2RE3 A;  1I5H W;  2DK1 A;  2YSF A;  3OOB A;  3WH0 A;  1TK7 A; 
#chains in the Genus database with same CATH topology
 3KAF A;  2QRV A;  2ZQV A;  1YW5 A;  2XPB A;  4GLX A;  2ZR4 A;  1O6W A;  2WAD A;  2XP7 A;  4REX A;  5E65 A;  2MDI A;  2JXW A;  2XP4 A;  3FSB A;  1K9R A;  1RP5 A;  1EG3 A;  2Q5A A;  2JX8 A;  2JV4 A;  5E62 A;  5U47 A;  1JMQ A;  3MQH A;  2YSI A;  2ZR5 A;  2YSH A;  2Y8N B;  2XP9 A;  3KCE A;  2ZR6 A;  3KAD A;  3KAG A;  2ITK A;  3KAH A;  4U86 A;  2BA1 A;  3LE4 A;  3NTP A;  1EG4 A;  2ZQS A;  2XP3 A;  4E5R A;  2ZQT A;  2YAJ B;  1F8A B;  2LAJ A;  2DJY A;  2L4J A;  1PIN A;  2OWO A;  2DK7 A;  5E5W A;  3TDB A;  2M3O W;  2M8J A;  2YSG A;  4QIB A;  4A0U A;  2E45 A;  1TR8 A;  2DWV A;  3KAI A;  4A0T A;  5AHT A;  3FS8 A;  1ZCN A;  3M7N A;  3L4H A;  3KAB A;  1WMV A;  3CNG A;  2XP8 A;  2F21 A;  5CQ2 A;  4U84 A;  2XP5 A;  3PQH A;  3MQG A;  3MCB B;  1WR7 A;  2KXQ A;  2M8I A;  1K9Q A;  2YSB A;  2ZAJ A;  2JMF A;  4U85 A;  1NMV A;  3TC5 A;  2XP6 A;  2ZQU A;  3LKX B;  5E64 A;  2EZ5 W;  2DMV A;  3M85 A;  2XPA A;  3ODK A;  3TCZ A;  1FLC A;  2RE3 A;  3MCB A;  1I5H W;  2DK1 A;  3FSC A;  3LKX A;  2YSF A;  3OOB A;  2WAE A;  3WH0 A;  5E66 A;  1TK7 A; 
#chains in the Genus database with same CATH homology
 3KAF A;  2QRV A;  2ZQV A;  1YW5 A;  2XPB A;  4GLX A;  2ZR4 A;  1O6W A;  2WAD A;  2XP7 A;  4REX A;  5E65 A;  2MDI A;  2JXW A;  2XP4 A;  3FSB A;  1K9R A;  1RP5 A;  1EG3 A;  2Q5A A;  2JX8 A;  2JV4 A;  5E62 A;  5U47 A;  1JMQ A;  3MQH A;  2YSI A;  2ZR5 A;  2YSH A;  2Y8N B;  2XP9 A;  3KCE A;  2ZR6 A;  3KAD A;  3KAG A;  2ITK A;  3KAH A;  4U86 A;  2BA1 A;  3LE4 A;  3NTP A;  1EG4 A;  2ZQS A;  2XP3 A;  4E5R A;  2ZQT A;  2YAJ B;  1F8A B;  2LAJ A;  2DJY A;  2L4J A;  1PIN A;  2OWO A;  2DK7 A;  5E5W A;  3TDB A;  2M3O W;  2M8J A;  2YSG A;  4QIB A;  4A0U A;  2E45 A;  1TR8 A;  2DWV A;  3KAI A;  4A0T A;  5AHT A;  3FS8 A;  1ZCN A;  3M7N A;  3L4H A;  3KAB A;  1WMV A;  3CNG A;  2XP8 A;  2F21 A;  5CQ2 A;  4U84 A;  2XP5 A;  3PQH A;  3MQG A;  3MCB B;  1WR7 A;  2KXQ A;  2M8I A;  1K9Q A;  2YSB A;  2ZAJ A;  2JMF A;  4U85 A;  1NMV A;  3TC5 A;  2XP6 A;  2ZQU A;  3LKX B;  5E64 A;  2EZ5 W;  2DMV A;  3M85 A;  2XPA A;  3ODK A;  3TCZ A;  1FLC A;  2RE3 A;  3MCB A;  1I5H W;  2DK1 A;  3FSC A;  3LKX A;  2YSF A;  3OOB A;  2WAE A;  3WH0 A;  5E66 A;  1TK7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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