3LE4A

Crystal structure of the dgcr8 dimerization domain
Total Genus 3
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
3
sequence length
55
structure length
55
Chain Sequence
PPTEPLPDGWIMTFHNSGVPVYLHRESRVVTWSRPYFLGTGSIRKHDPPLSSIPC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structure of the dimerization domain of DiGeorge Critical Region 8
pubmed doi rcsb
molecule tags Nuclear protein
source organism Homo sapiens
molecule keywords Microprocessor complex subunit DGCR8
total genus 3
structure length 55
sequence length 55
ec nomenclature
pdb deposition date 2010-01-14
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.70.10 Mainly Beta Single Sheet Ubiquitin Ligase Nedd4; Chain: W; Ubiquitin Ligase Nedd4; Chain: W; 3le4A00
4QIBA 2ZQVA 2YSFA 2ZQUA 3M7NA 2LAJA 2RE3A 5CQ2A 2XPAA 2M8JA 3KAHA 4U85A 1EG3A 1F8AB 5AHTA 3TCZA 3LE4A 3KABA 2EZ5W 2ZR5A 2ZR6A 3WH0A 3L4HA 2XP4A 3KAIA 2JV4A 3OOBA 2JX8A 2M8IA 1YW5A 3KCEA 2ZR4A 2XPBA 2XP5A 3TDBA 2Q5AA 4U86A 2YSBA 2DMVA 4U84A 2E45A 3KADA 1PINA 2ZQSA 2YSGA 2KXQA 2XP7A 3KAFA 2F21A 2DK7A 2XP3A 2MDIA 2XP9A 2XP6A 1O6WA 2DWVA 2JXWA 2XP8A 2DJYA 3KAGA 3ODKA 2ITKA 1ZCNA 1K9QA 2DK1A 1JMQA 1K9RA 2ZQTA 2ZAJA 1I5HW 3M85A 1EG4A 2YSIA 2JMFA 1TK7A 4REXA 1WR7A 1NMVA 3NTPA 2BA1A 2M3OW 3CNGA 2YSHA 3TC5A 4E5RA 2L4JA 1WMVA
chains in the Genus database with same CATH superfamily
4QIBA 2WAEA 5U47A 2ZQVA 2YSFA 3FS8A 2ZQUA 3M7NA 2LAJA 2RE3A 5CQ2A 1RP5A 2XPAA 4A0UA 2M8JA 3KAHA 4U85A 1EG3A 1F8AB 5AHTA 3TCZA 3LE4A 2Y8NB 4A0TA 3KABA 2EZ5W 2ZR5A 2ZR6A 2QRVA 3WH0A 3L4HA 2XP4A 3KAIA 2JV4A 3OOBA 1FLCA 2JX8A 2M8IA 1YW5A 3KCEA 3LKXA 3MCBA 5E62A 2ZR4A 2XPBA 2YAJB 2XP5A 3TDBA 2Q5AA 4U86A 2YSBA 2DMVA 4U84A 5E66A 2E45A 3KADA 2WADA 1PINA 2ZQSA 2YSGA 4GLXA 2KXQA 2XP7A 3KAFA 2F21A 2DK7A 2XP3A 2MDIA 2XP9A 2XP6A 1O6WA 3MCBB 2DWVA 2JXWA 2XP8A 2DJYA 4E5RA 3KAGA 3ODKA 3MQGA 5E65A 2ITKA 3PQHA 2OWOA 1ZCNA 1K9QA 2DK1A 1JMQA 1K9RA 2ZQTA 2ZAJA 1I5HW 3M85A 1EG4A 2YSIA 2JMFA 1TK7A 4REXA 1WR7A 5E64A 3LKXB 1NMVA 3MQHA 5E5WA 3NTPA 2BA1A 3FSCA 3FSBA 2M3OW 3CNGA 2YSHA 3TC5A 1TR8A 2L4JA 1WMVA
chains in the Genus database with same CATH topology
4QIBA 2WAEA 5U47A 2ZQVA 2YSFA 3FS8A 2ZQUA 3M7NA 2LAJA 2RE3A 5CQ2A 1RP5A 2XPAA 4A0UA 2M8JA 3KAHA 4U85A 1EG3A 1F8AB 5AHTA 3TCZA 3LE4A 2Y8NB 4A0TA 3KABA 2EZ5W 2ZR5A 2ZR6A 2QRVA 3WH0A 3L4HA 2XP4A 3KAIA 2JV4A 3OOBA 1FLCA 2JX8A 2M8IA 1YW5A 3KCEA 3LKXA 3MCBA 5E62A 2ZR4A 2XPBA 2YAJB 2XP5A 3TDBA 2Q5AA 4U86A 2YSBA 2DMVA 4U84A 5E66A 2E45A 3KADA 2WADA 1PINA 2ZQSA 2YSGA 4GLXA 2KXQA 2XP7A 3KAFA 2F21A 2DK7A 2XP3A 2MDIA 2XP9A 2XP6A 1O6WA 3MCBB 2DWVA 2JXWA 2XP8A 2DJYA 4E5RA 3KAGA 3ODKA 3MQGA 5E65A 2ITKA 3PQHA 2OWOA 1ZCNA 1K9QA 2DK1A 1JMQA 1K9RA 2ZQTA 2ZAJA 1I5HW 3M85A 1EG4A 2YSIA 2JMFA 1TK7A 4REXA 1WR7A 5E64A 3LKXB 1NMVA 3MQHA 5E5WA 3NTPA 2BA1A 3FSCA 3FSBA 2M3OW 3CNGA 2YSHA 3TC5A 1TR8A 2L4JA 1WMVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4QIB A;  2ZQV A;  2YSF A;  2ZQU A;  3M7N A;  2LAJ A;  2RE3 A;  5CQ2 A;  2XPA A;  2M8J A;  3KAH A;  4U85 A;  1EG3 A;  1F8A B;  5AHT A;  3TCZ A;  3LE4 A;  3KAB A;  2EZ5 W;  2ZR5 A;  2ZR6 A;  3WH0 A;  3L4H A;  2XP4 A;  3KAI A;  2JV4 A;  3OOB A;  2JX8 A;  2M8I A;  1YW5 A;  3KCE A;  2ZR4 A;  2XPB A;  2XP5 A;  3TDB A;  2Q5A A;  4U86 A;  2YSB A;  2DMV A;  4U84 A;  2E45 A;  3KAD A;  1PIN A;  2ZQS A;  2YSG A;  2KXQ A;  2XP7 A;  3KAF A;  2F21 A;  2DK7 A;  2XP3 A;  2MDI A;  2XP9 A;  2XP6 A;  1O6W A;  2DWV A;  2JXW A;  2XP8 A;  2DJY A;  3KAG A;  3ODK A;  2ITK A;  1ZCN A;  1K9Q A;  2DK1 A;  1JMQ A;  1K9R A;  2ZQT A;  2ZAJ A;  1I5H W;  3M85 A;  1EG4 A;  2YSI A;  2JMF A;  1TK7 A;  4REX A;  1WR7 A;  1NMV A;  3NTP A;  2BA1 A;  2M3O W;  3CNG A;  2YSH A;  3TC5 A;  4E5R A;  2L4J A;  1WMV A; 
#chains in the Genus database with same CATH topology
 4QIB A;  2WAE A;  5U47 A;  2ZQV A;  2YSF A;  3FS8 A;  2ZQU A;  3M7N A;  2LAJ A;  2RE3 A;  5CQ2 A;  1RP5 A;  2XPA A;  4A0U A;  2M8J A;  3KAH A;  4U85 A;  1EG3 A;  1F8A B;  5AHT A;  3TCZ A;  3LE4 A;  2Y8N B;  4A0T A;  3KAB A;  2EZ5 W;  2ZR5 A;  2ZR6 A;  2QRV A;  3WH0 A;  3L4H A;  2XP4 A;  3KAI A;  2JV4 A;  3OOB A;  1FLC A;  2JX8 A;  2M8I A;  1YW5 A;  3KCE A;  3LKX A;  3MCB A;  5E62 A;  2ZR4 A;  2XPB A;  2YAJ B;  2XP5 A;  3TDB A;  2Q5A A;  4U86 A;  2YSB A;  2DMV A;  4U84 A;  5E66 A;  2E45 A;  3KAD A;  2WAD A;  1PIN A;  2ZQS A;  2YSG A;  4GLX A;  2KXQ A;  2XP7 A;  3KAF A;  2F21 A;  2DK7 A;  2XP3 A;  2MDI A;  2XP9 A;  2XP6 A;  1O6W A;  3MCB B;  2DWV A;  2JXW A;  2XP8 A;  2DJY A;  4E5R A;  3KAG A;  3ODK A;  3MQG A;  5E65 A;  2ITK A;  3PQH A;  2OWO A;  1ZCN A;  1K9Q A;  2DK1 A;  1JMQ A;  1K9R A;  2ZQT A;  2ZAJ A;  1I5H W;  3M85 A;  1EG4 A;  2YSI A;  2JMF A;  1TK7 A;  4REX A;  1WR7 A;  5E64 A;  3LKX B;  1NMV A;  3MQH A;  5E5W A;  3NTP A;  2BA1 A;  3FSC A;  3FSB A;  2M3O W;  3CNG A;  2YSH A;  3TC5 A;  1TR8 A;  2L4J A;  1WMV A; 
#chains in the Genus database with same CATH homology
 4QIB A;  2WAE A;  5U47 A;  2ZQV A;  2YSF A;  3FS8 A;  2ZQU A;  3M7N A;  2LAJ A;  2RE3 A;  5CQ2 A;  1RP5 A;  2XPA A;  4A0U A;  2M8J A;  3KAH A;  4U85 A;  1EG3 A;  1F8A B;  5AHT A;  3TCZ A;  3LE4 A;  2Y8N B;  4A0T A;  3KAB A;  2EZ5 W;  2ZR5 A;  2ZR6 A;  2QRV A;  3WH0 A;  3L4H A;  2XP4 A;  3KAI A;  2JV4 A;  3OOB A;  1FLC A;  2JX8 A;  2M8I A;  1YW5 A;  3KCE A;  3LKX A;  3MCB A;  5E62 A;  2ZR4 A;  2XPB A;  2YAJ B;  2XP5 A;  3TDB A;  2Q5A A;  4U86 A;  2YSB A;  2DMV A;  4U84 A;  5E66 A;  2E45 A;  3KAD A;  2WAD A;  1PIN A;  2ZQS A;  2YSG A;  4GLX A;  2KXQ A;  2XP7 A;  3KAF A;  2F21 A;  2DK7 A;  2XP3 A;  2MDI A;  2XP9 A;  2XP6 A;  1O6W A;  3MCB B;  2DWV A;  2JXW A;  2XP8 A;  2DJY A;  4E5R A;  3KAG A;  3ODK A;  3MQG A;  5E65 A;  2ITK A;  3PQH A;  2OWO A;  1ZCN A;  1K9Q A;  2DK1 A;  1JMQ A;  1K9R A;  2ZQT A;  2ZAJ A;  1I5H W;  3M85 A;  1EG4 A;  2YSI A;  2JMF A;  1TK7 A;  4REX A;  1WR7 A;  5E64 A;  3LKX B;  1NMV A;  3MQH A;  5E5W A;  3NTP A;  2BA1 A;  3FSC A;  3FSB A;  2M3O W;  3CNG A;  2YSH A;  3TC5 A;  1TR8 A;  2L4J A;  1WMV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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