4E5RA

Crystal structure of frog dgcr8 dimerization domain
Total Genus 4
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
4
sequence length
56
structure length
56
Chain Sequence
PPTEPLPDGWIMTFHNSGLPVYLHRETRVVTWSRPYFLGTGSIRKHDPPISSIPCL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Dimerization and heme binding are conserved in amphibian and starfish homologues of the microRNA processing protein DGCR8.
pubmed doi rcsb
molecule tags Rna binding protein
source organism Xenopus laevis
molecule keywords MGC78846 protein
total genus 4
structure length 56
sequence length 56
ec nomenclature
pdb deposition date 2012-03-14
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.70.10 Mainly Beta Single Sheet Ubiquitin Ligase Nedd4; Chain: W; Ubiquitin Ligase Nedd4; Chain: W; 4e5rA00
2E45A 1WR7A 4E5RA 2F21A 2DMVA 2DK7A 3KADA 2JX8A 2MDIA 1K9QA 2XP3A 3TDBA 4U86A 2JMFA 2Q5AA 4U85A 2ZR5A 3M7NA 1PINA 2XPAA 1YW5A 1I5HW 2DWVA 3KAHA 3NTPA 1TK7A 2BA1A 2JXWA 3KAGA 2LAJA 2XP9A 2ZQVA 5CQ2A 2YSBA 4REXA 3KAIA 2XPBA 2YSGA 2ZAJA 2ZR6A 1F8AB 4U84A 3M85A 5AHTA 2ZQTA 3TCZA 2XP4A 4QIBA 2EZ5W 2YSIA 1JMQA 2DJYA 2L4JA 2XP8A 3LE4A 2ZQSA 3KABA 2RE3A 2XP7A 1ZCNA 3TC5A 2M3OW 1NMVA 2DK1A 3KCEA 2KXQA 3CNGA 2M8IA 3ODKA 2YSFA 1K9RA 1EG4A 1EG3A 2M8JA 2JV4A 2XP6A 1WMVA 2XP5A 3KAFA 3WH0A 2YSHA 2ZQUA 3OOBA 1O6WA 2ZR4A 3L4HA 2ITKA
chains in the Genus database with same CATH superfamily
2E45A 1WR7A 5E66A 4E5RA 4A0TA 5E5WA 2F21A 2DMVA 2DK7A 3KADA 1RP5A 3FSBA 2JX8A 2MDIA 1K9QA 2XP3A 3TDBA 4U86A 3MQGA 2JMFA 2Q5AA 4U85A 2ZR5A 5U47A 4A0UA 3M7NA 1PINA 2Y8NB 2XPAA 1TR8A 1YW5A 1I5HW 2DWVA 3KAHA 3NTPA 2YAJB 1TK7A 5E62A 2BA1A 2JXWA 3KAGA 2LAJA 2XP9A 2ZQVA 5CQ2A 2YSBA 4REXA 3KAIA 2XPBA 2YSGA 2ZAJA 4GLXA 2ZR6A 1F8AB 4U84A 3M85A 2WAEA 5AHTA 5E65A 2ZQTA 3TCZA 1FLCA 2XP4A 4QIBA 2EZ5W 2YSIA 1JMQA 2DJYA 2L4JA 3LKXA 2XP8A 3LE4A 2ZQSA 2WADA 3FSCA 3MQHA 3KABA 2RE3A 2XP7A 1ZCNA 3MCBA 3TC5A 2M3OW 2QRVA 1NMVA 2DK1A 3KCEA 2KXQA 3CNGA 2M8IA 3LKXB 3ODKA 2YSFA 1K9RA 1EG4A 1EG3A 3MCBB 2M8JA 2JV4A 3PQHA 2XP6A 1WMVA 2XP5A 3KAFA 3WH0A 2YSHA 2ZQUA 3OOBA 1O6WA 5E64A 2OWOA 3FS8A 2ZR4A 3L4HA 2ITKA
chains in the Genus database with same CATH topology
2E45A 1WR7A 5E66A 4E5RA 4A0TA 5E5WA 2F21A 2DMVA 2DK7A 3KADA 1RP5A 3FSBA 2JX8A 2MDIA 1K9QA 2XP3A 3TDBA 4U86A 3MQGA 2JMFA 2Q5AA 4U85A 2ZR5A 5U47A 4A0UA 3M7NA 1PINA 2Y8NB 2XPAA 1TR8A 1YW5A 1I5HW 2DWVA 3KAHA 3NTPA 2YAJB 1TK7A 5E62A 2BA1A 2JXWA 3KAGA 2LAJA 2XP9A 2ZQVA 5CQ2A 2YSBA 4REXA 3KAIA 2XPBA 2YSGA 2ZAJA 4GLXA 2ZR6A 1F8AB 4U84A 3M85A 2WAEA 5AHTA 5E65A 2ZQTA 3TCZA 1FLCA 2XP4A 4QIBA 2EZ5W 2YSIA 1JMQA 2DJYA 2L4JA 3LKXA 2XP8A 3LE4A 2ZQSA 2WADA 3FSCA 3MQHA 3KABA 2RE3A 2XP7A 1ZCNA 3MCBA 3TC5A 2M3OW 2QRVA 1NMVA 2DK1A 3KCEA 2KXQA 3CNGA 2M8IA 3LKXB 3ODKA 2YSFA 1K9RA 1EG4A 1EG3A 3MCBB 2M8JA 2JV4A 3PQHA 2XP6A 1WMVA 2XP5A 3KAFA 3WH0A 2YSHA 2ZQUA 3OOBA 1O6WA 5E64A 2OWOA 3FS8A 2ZR4A 3L4HA 2ITKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2E45 A;  1WR7 A;  4E5R A;  2F21 A;  2DMV A;  2DK7 A;  3KAD A;  2JX8 A;  2MDI A;  1K9Q A;  2XP3 A;  3TDB A;  4U86 A;  2JMF A;  2Q5A A;  4U85 A;  2ZR5 A;  3M7N A;  1PIN A;  2XPA A;  1YW5 A;  1I5H W;  2DWV A;  3KAH A;  3NTP A;  1TK7 A;  2BA1 A;  2JXW A;  3KAG A;  2LAJ A;  2XP9 A;  2ZQV A;  5CQ2 A;  2YSB A;  4REX A;  3KAI A;  2XPB A;  2YSG A;  2ZAJ A;  2ZR6 A;  1F8A B;  4U84 A;  3M85 A;  5AHT A;  2ZQT A;  3TCZ A;  2XP4 A;  4QIB A;  2EZ5 W;  2YSI A;  1JMQ A;  2DJY A;  2L4J A;  2XP8 A;  3LE4 A;  2ZQS A;  3KAB A;  2RE3 A;  2XP7 A;  1ZCN A;  3TC5 A;  2M3O W;  1NMV A;  2DK1 A;  3KCE A;  2KXQ A;  3CNG A;  2M8I A;  3ODK A;  2YSF A;  1K9R A;  1EG4 A;  1EG3 A;  2M8J A;  2JV4 A;  2XP6 A;  1WMV A;  2XP5 A;  3KAF A;  3WH0 A;  2YSH A;  2ZQU A;  3OOB A;  1O6W A;  2ZR4 A;  3L4H A;  2ITK A; 
#chains in the Genus database with same CATH topology
 2E45 A;  1WR7 A;  5E66 A;  4E5R A;  4A0T A;  5E5W A;  2F21 A;  2DMV A;  2DK7 A;  3KAD A;  1RP5 A;  3FSB A;  2JX8 A;  2MDI A;  1K9Q A;  2XP3 A;  3TDB A;  4U86 A;  3MQG A;  2JMF A;  2Q5A A;  4U85 A;  2ZR5 A;  5U47 A;  4A0U A;  3M7N A;  1PIN A;  2Y8N B;  2XPA A;  1TR8 A;  1YW5 A;  1I5H W;  2DWV A;  3KAH A;  3NTP A;  2YAJ B;  1TK7 A;  5E62 A;  2BA1 A;  2JXW A;  3KAG A;  2LAJ A;  2XP9 A;  2ZQV A;  5CQ2 A;  2YSB A;  4REX A;  3KAI A;  2XPB A;  2YSG A;  2ZAJ A;  4GLX A;  2ZR6 A;  1F8A B;  4U84 A;  3M85 A;  2WAE A;  5AHT A;  5E65 A;  2ZQT A;  3TCZ A;  1FLC A;  2XP4 A;  4QIB A;  2EZ5 W;  2YSI A;  1JMQ A;  2DJY A;  2L4J A;  3LKX A;  2XP8 A;  3LE4 A;  2ZQS A;  2WAD A;  3FSC A;  3MQH A;  3KAB A;  2RE3 A;  2XP7 A;  1ZCN A;  3MCB A;  3TC5 A;  2M3O W;  2QRV A;  1NMV A;  2DK1 A;  3KCE A;  2KXQ A;  3CNG A;  2M8I A;  3LKX B;  3ODK A;  2YSF A;  1K9R A;  1EG4 A;  1EG3 A;  3MCB B;  2M8J A;  2JV4 A;  3PQH A;  2XP6 A;  1WMV A;  2XP5 A;  3KAF A;  3WH0 A;  2YSH A;  2ZQU A;  3OOB A;  1O6W A;  5E64 A;  2OWO A;  3FS8 A;  2ZR4 A;  3L4H A;  2ITK A; 
#chains in the Genus database with same CATH homology
 2E45 A;  1WR7 A;  5E66 A;  4E5R A;  4A0T A;  5E5W A;  2F21 A;  2DMV A;  2DK7 A;  3KAD A;  1RP5 A;  3FSB A;  2JX8 A;  2MDI A;  1K9Q A;  2XP3 A;  3TDB A;  4U86 A;  3MQG A;  2JMF A;  2Q5A A;  4U85 A;  2ZR5 A;  5U47 A;  4A0U A;  3M7N A;  1PIN A;  2Y8N B;  2XPA A;  1TR8 A;  1YW5 A;  1I5H W;  2DWV A;  3KAH A;  3NTP A;  2YAJ B;  1TK7 A;  5E62 A;  2BA1 A;  2JXW A;  3KAG A;  2LAJ A;  2XP9 A;  2ZQV A;  5CQ2 A;  2YSB A;  4REX A;  3KAI A;  2XPB A;  2YSG A;  2ZAJ A;  4GLX A;  2ZR6 A;  1F8A B;  4U84 A;  3M85 A;  2WAE A;  5AHT A;  5E65 A;  2ZQT A;  3TCZ A;  1FLC A;  2XP4 A;  4QIB A;  2EZ5 W;  2YSI A;  1JMQ A;  2DJY A;  2L4J A;  3LKX A;  2XP8 A;  3LE4 A;  2ZQS A;  2WAD A;  3FSC A;  3MQH A;  3KAB A;  2RE3 A;  2XP7 A;  1ZCN A;  3MCB A;  3TC5 A;  2M3O W;  2QRV A;  1NMV A;  2DK1 A;  3KCE A;  2KXQ A;  3CNG A;  2M8I A;  3LKX B;  3ODK A;  2YSF A;  1K9R A;  1EG4 A;  1EG3 A;  3MCB B;  2M8J A;  2JV4 A;  3PQH A;  2XP6 A;  1WMV A;  2XP5 A;  3KAF A;  3WH0 A;  2YSH A;  2ZQU A;  3OOB A;  1O6W A;  5E64 A;  2OWO A;  3FS8 A;  2ZR4 A;  3L4H A;  2ITK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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