4E5RA

Crystal structure of frog dgcr8 dimerization domain
Total Genus 4
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
4
sequence length
56
structure length
56
Chain Sequence
PPTEPLPDGWIMTFHNSGLPVYLHRETRVVTWSRPYFLGTGSIRKHDPPISSIPCL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Rna binding protein
source organism Xenopus laevis
publication title Dimerization and heme binding are conserved in amphibian and starfish homologues of the microRNA processing protein DGCR8.
pubmed doi rcsb
molecule keywords MGC78846 protein
total genus 4
structure length 56
sequence length 56
ec nomenclature
pdb deposition date 2012-03-14
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.70.10 Mainly Beta Single Sheet Ubiquitin Ligase Nedd4; Chain: W; Ubiquitin Ligase Nedd4; Chain: W; 4e5rA00
2XPBA 3KCEA 4QIBA 3L4HA 2JV4A 2JMFA 2M3OW 1O6WA 3TC5A 1EG4A 2F21A 1K9RA 2XP5A 2RE3A 2DMVA 2M8JA 2YSBA 2ZQSA 3KAIA 2ZQVA 1I5HW 2DK1A 4REXA 4U86A 2ZQTA 2XPAA 2KXQA 2YSGA 4E5RA 3KABA 2XP7A 1WR7A 3CNGA 2ZR5A 3OOBA 1NMVA 4U84A 2ZR4A 1F8AB 2ZAJA 1YW5A 5CQ2A 3WH0A 2L4JA 2XP4A 1ZCNA 1EG3A 1WMVA 2DWVA 2E45A 3NTPA 4U85A 1K9QA 2XP9A 2YSFA 3TCZA 3KAFA 2EZ5W 3KADA 2DJYA 2LAJA 3KAHA 3KAGA 2DK7A 3M7NA 2JX8A 2Q5AA 2XP3A 2JXWA 2BA1A 2MDIA 2YSHA 2ZR6A 1PINA 1TK7A 2M8IA 2YSIA 2ITKA 1JMQA 3M85A 2ZQUA 5AHTA 2XP8A 3ODKA 2XP6A 3LE4A 3TDBA
chains in the Genus database with same CATH superfamily
2XPBA 2WADA 5E5WA 3KCEA 4QIBA 3L4HA 2JV4A 2JMFA 2M3OW 1O6WA 5E64A 3TC5A 2YAJB 1EG4A 2F21A 1K9RA 2XP5A 2RE3A 2DMVA 2M8JA 2Y8NB 2YSBA 2ZQSA 3KAIA 2ZQVA 1I5HW 2DK1A 4REXA 4U86A 2ZQTA 2XPAA 2KXQA 2YSGA 4E5RA 3KABA 2XP7A 1WR7A 3CNGA 2ZR5A 3FSBA 3OOBA 4GLXA 1NMVA 4U84A 2ZR4A 3MQHA 1F8AB 5E66A 5E65A 2ZAJA 1YW5A 3MCBA 5CQ2A 3WH0A 2L4JA 2XP4A 1ZCNA 3FSCA 1EG3A 1WMVA 2DWVA 2E45A 3FS8A 3NTPA 4U85A 3LKXA 1K9QA 4A0UA 2XP9A 2YSFA 3TCZA 3KAFA 2EZ5W 5E62A 1TR8A 3KADA 3MCBB 3MQGA 2WAEA 2DJYA 2LAJA 3LKXB 3KAHA 3KAGA 5U47A 3PQHA 2DK7A 3M7NA 2JX8A 2Q5AA 1RP5A 2XP3A 2JXWA 2BA1A 2MDIA 2YSHA 2ZR6A 1PINA 1TK7A 2M8IA 2OWOA 2YSIA 2QRVA 2ITKA 1JMQA 4A0TA 3M85A 2ZQUA 5AHTA 2XP8A 3ODKA 2XP6A 1FLCA 3LE4A 3TDBA
chains in the Genus database with same CATH topology
2XPBA 2WADA 5E5WA 3KCEA 4QIBA 3L4HA 2JV4A 2JMFA 2M3OW 1O6WA 5E64A 3TC5A 2YAJB 1EG4A 2F21A 1K9RA 2XP5A 2RE3A 2DMVA 2M8JA 2Y8NB 2YSBA 2ZQSA 3KAIA 2ZQVA 1I5HW 2DK1A 4REXA 4U86A 2ZQTA 2XPAA 2KXQA 2YSGA 4E5RA 3KABA 2XP7A 1WR7A 3CNGA 2ZR5A 3FSBA 3OOBA 4GLXA 1NMVA 4U84A 2ZR4A 3MQHA 1F8AB 5E66A 5E65A 2ZAJA 1YW5A 3MCBA 5CQ2A 3WH0A 2L4JA 2XP4A 1ZCNA 3FSCA 1EG3A 1WMVA 2DWVA 2E45A 3FS8A 3NTPA 4U85A 3LKXA 1K9QA 4A0UA 2XP9A 2YSFA 3TCZA 3KAFA 2EZ5W 5E62A 1TR8A 3KADA 3MCBB 3MQGA 2WAEA 2DJYA 2LAJA 3LKXB 3KAHA 3KAGA 5U47A 3PQHA 2DK7A 3M7NA 2JX8A 2Q5AA 1RP5A 2XP3A 2JXWA 2BA1A 2MDIA 2YSHA 2ZR6A 1PINA 1TK7A 2M8IA 2OWOA 2YSIA 2QRVA 2ITKA 1JMQA 4A0TA 3M85A 2ZQUA 5AHTA 2XP8A 3ODKA 2XP6A 1FLCA 3LE4A 3TDBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2XPB A;  3KCE A;  4QIB A;  3L4H A;  2JV4 A;  2JMF A;  2M3O W;  1O6W A;  3TC5 A;  1EG4 A;  2F21 A;  1K9R A;  2XP5 A;  2RE3 A;  2DMV A;  2M8J A;  2YSB A;  2ZQS A;  3KAI A;  2ZQV A;  1I5H W;  2DK1 A;  4REX A;  4U86 A;  2ZQT A;  2XPA A;  2KXQ A;  2YSG A;  4E5R A;  3KAB A;  2XP7 A;  1WR7 A;  3CNG A;  2ZR5 A;  3OOB A;  1NMV A;  4U84 A;  2ZR4 A;  1F8A B;  2ZAJ A;  1YW5 A;  5CQ2 A;  3WH0 A;  2L4J A;  2XP4 A;  1ZCN A;  1EG3 A;  1WMV A;  2DWV A;  2E45 A;  3NTP A;  4U85 A;  1K9Q A;  2XP9 A;  2YSF A;  3TCZ A;  3KAF A;  2EZ5 W;  3KAD A;  2DJY A;  2LAJ A;  3KAH A;  3KAG A;  2DK7 A;  3M7N A;  2JX8 A;  2Q5A A;  2XP3 A;  2JXW A;  2BA1 A;  2MDI A;  2YSH A;  2ZR6 A;  1PIN A;  1TK7 A;  2M8I A;  2YSI A;  2ITK A;  1JMQ A;  3M85 A;  2ZQU A;  5AHT A;  2XP8 A;  3ODK A;  2XP6 A;  3LE4 A;  3TDB A; 
#chains in the Genus database with same CATH topology
 2XPB A;  2WAD A;  5E5W A;  3KCE A;  4QIB A;  3L4H A;  2JV4 A;  2JMF A;  2M3O W;  1O6W A;  5E64 A;  3TC5 A;  2YAJ B;  1EG4 A;  2F21 A;  1K9R A;  2XP5 A;  2RE3 A;  2DMV A;  2M8J A;  2Y8N B;  2YSB A;  2ZQS A;  3KAI A;  2ZQV A;  1I5H W;  2DK1 A;  4REX A;  4U86 A;  2ZQT A;  2XPA A;  2KXQ A;  2YSG A;  4E5R A;  3KAB A;  2XP7 A;  1WR7 A;  3CNG A;  2ZR5 A;  3FSB A;  3OOB A;  4GLX A;  1NMV A;  4U84 A;  2ZR4 A;  3MQH A;  1F8A B;  5E66 A;  5E65 A;  2ZAJ A;  1YW5 A;  3MCB A;  5CQ2 A;  3WH0 A;  2L4J A;  2XP4 A;  1ZCN A;  3FSC A;  1EG3 A;  1WMV A;  2DWV A;  2E45 A;  3FS8 A;  3NTP A;  4U85 A;  3LKX A;  1K9Q A;  4A0U A;  2XP9 A;  2YSF A;  3TCZ A;  3KAF A;  2EZ5 W;  5E62 A;  1TR8 A;  3KAD A;  3MCB B;  3MQG A;  2WAE A;  2DJY A;  2LAJ A;  3LKX B;  3KAH A;  3KAG A;  5U47 A;  3PQH A;  2DK7 A;  3M7N A;  2JX8 A;  2Q5A A;  1RP5 A;  2XP3 A;  2JXW A;  2BA1 A;  2MDI A;  2YSH A;  2ZR6 A;  1PIN A;  1TK7 A;  2M8I A;  2OWO A;  2YSI A;  2QRV A;  2ITK A;  1JMQ A;  4A0T A;  3M85 A;  2ZQU A;  5AHT A;  2XP8 A;  3ODK A;  2XP6 A;  1FLC A;  3LE4 A;  3TDB A; 
#chains in the Genus database with same CATH homology
 2XPB A;  2WAD A;  5E5W A;  3KCE A;  4QIB A;  3L4H A;  2JV4 A;  2JMF A;  2M3O W;  1O6W A;  5E64 A;  3TC5 A;  2YAJ B;  1EG4 A;  2F21 A;  1K9R A;  2XP5 A;  2RE3 A;  2DMV A;  2M8J A;  2Y8N B;  2YSB A;  2ZQS A;  3KAI A;  2ZQV A;  1I5H W;  2DK1 A;  4REX A;  4U86 A;  2ZQT A;  2XPA A;  2KXQ A;  2YSG A;  4E5R A;  3KAB A;  2XP7 A;  1WR7 A;  3CNG A;  2ZR5 A;  3FSB A;  3OOB A;  4GLX A;  1NMV A;  4U84 A;  2ZR4 A;  3MQH A;  1F8A B;  5E66 A;  5E65 A;  2ZAJ A;  1YW5 A;  3MCB A;  5CQ2 A;  3WH0 A;  2L4J A;  2XP4 A;  1ZCN A;  3FSC A;  1EG3 A;  1WMV A;  2DWV A;  2E45 A;  3FS8 A;  3NTP A;  4U85 A;  3LKX A;  1K9Q A;  4A0U A;  2XP9 A;  2YSF A;  3TCZ A;  3KAF A;  2EZ5 W;  5E62 A;  1TR8 A;  3KAD A;  3MCB B;  3MQG A;  2WAE A;  2DJY A;  2LAJ A;  3LKX B;  3KAH A;  3KAG A;  5U47 A;  3PQH A;  2DK7 A;  3M7N A;  2JX8 A;  2Q5A A;  1RP5 A;  2XP3 A;  2JXW A;  2BA1 A;  2MDI A;  2YSH A;  2ZR6 A;  1PIN A;  1TK7 A;  2M8I A;  2OWO A;  2YSI A;  2QRV A;  2ITK A;  1JMQ A;  4A0T A;  3M85 A;  2ZQU A;  5AHT A;  2XP8 A;  3ODK A;  2XP6 A;  1FLC A;  3LE4 A;  3TDB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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