4REXA

Crystal structure of the first ww domain of human yap2 isoform
Total Genus 8
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
8
sequence length
48
structure length
48
Chain Sequence
GAMGFEIPDDVPLPAGWEMAKTSSGQRYFLNHIDQTTTWQDPRKAMLS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Protein binding
source organism Homo sapiens
publication title Crystal structure of the first WW domain of human YAP2 isoform.
pubmed doi rcsb
molecule keywords Yorkie homolog
total genus 8
structure length 48
sequence length 48
ec nomenclature
pdb deposition date 2014-09-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00397 WW WW domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.70.10 Mainly Beta Single Sheet Ubiquitin Ligase Nedd4; Chain: W; Ubiquitin Ligase Nedd4; Chain: W; 4rexA00
3TDBA 2XP6A 2YSFA 4U85A 2XPBA 2JXWA 2L4JA 2XPAA 2ZQVA 3ODKA 2YSGA 2ZQTA 3L4HA 2JX8A 2ZR4A 4REXA 2DMVA 2ZR5A 2XP8A 3WH0A 2DWVA 3KCEA 3KAFA 2XP4A 1NMVA 2YSIA 2RE3A 3KAGA 2LAJA 2MDIA 2F21A 2Q5AA 2E45A 2KXQA 1WMVA 3CNGA 3KAHA 3KAIA 3LE4A 2XP3A 3KABA 4QIBA 2DJYA 5CQ2A 2M8IA 2JV4A 3TC5A 3KADA 2ITKA 2M8JA 2YSHA 2XP7A 2JMFA 1ZCNA 4U84A 1F8AB 2DK1A 2XP9A 2ZQSA 1K9RA 1JMQA 2EZ5W 5AHTA 2YSBA 2ZR6A 2DK7A 2M3OW 1PINA 1O6WA 1K9QA 1YW5A 3M7NA 3NTPA 3TCZA 2ZAJA 2XP5A 4E5RA 3M85A 1TK7A 2BA1A 2ZQUA 1EG4A 1I5HW 1EG3A 4U86A 1WR7A 3OOBA
chains in the Genus database with same CATH superfamily
3TDBA 5E65A 2WADA 1TR8A 2XP6A 2YSFA 4U85A 2XPBA 1FLCA 4GLXA 3FS8A 2JXWA 2L4JA 2YAJB 2XPAA 2ZQVA 3LKXB 3ODKA 2YSGA 2ZQTA 3L4HA 2JX8A 2ZR4A 4REXA 2DMVA 2ZR5A 3PQHA 3MCBA 2XP8A 3WH0A 2DWVA 2QRVA 3KCEA 3KAFA 2XP4A 1NMVA 2YSIA 2RE3A 3KAGA 2LAJA 2MDIA 2F21A 2Q5AA 2E45A 2KXQA 1WMVA 3CNGA 3FSCA 3KAHA 3KAIA 5E64A 3LE4A 2XP3A 3KABA 4QIBA 2DJYA 4A0TA 5CQ2A 5U47A 2M8IA 2JV4A 3TC5A 3KADA 2ITKA 2M8JA 1RP5A 2YSHA 2XP7A 2JMFA 1ZCNA 4A0UA 4U84A 1F8AB 3MCBB 3LKXA 2DK1A 2XP9A 2WAEA 2ZQSA 1K9RA 1JMQA 2EZ5W 5AHTA 3MQGA 2YSBA 2ZR6A 2DK7A 3FSBA 2M3OW 1O6WA 1PINA 5E66A 1K9QA 2Y8NB 1YW5A 5E5WA 3M7NA 3NTPA 3TCZA 2ZAJA 2XP5A 4E5RA 3M85A 1TK7A 2BA1A 2ZQUA 1EG4A 1I5HW 3MQHA 1EG3A 4U86A 5E62A 1WR7A 3OOBA 2OWOA
chains in the Genus database with same CATH topology
3TDBA 5E65A 2WADA 1TR8A 2XP6A 2YSFA 4U85A 2XPBA 1FLCA 4GLXA 3FS8A 2JXWA 2L4JA 2YAJB 2XPAA 2ZQVA 3LKXB 3ODKA 2YSGA 2ZQTA 3L4HA 2JX8A 2ZR4A 4REXA 2DMVA 2ZR5A 3PQHA 3MCBA 2XP8A 3WH0A 2DWVA 2QRVA 3KCEA 3KAFA 2XP4A 1NMVA 2YSIA 2RE3A 3KAGA 2LAJA 2MDIA 2F21A 2Q5AA 2E45A 2KXQA 1WMVA 3CNGA 3FSCA 3KAHA 3KAIA 5E64A 3LE4A 2XP3A 3KABA 4QIBA 2DJYA 4A0TA 5CQ2A 5U47A 2M8IA 2JV4A 3TC5A 3KADA 2ITKA 2M8JA 1RP5A 2YSHA 2XP7A 2JMFA 1ZCNA 4A0UA 4U84A 1F8AB 3MCBB 3LKXA 2DK1A 2XP9A 2WAEA 2ZQSA 1K9RA 1JMQA 2EZ5W 5AHTA 3MQGA 2YSBA 2ZR6A 2DK7A 3FSBA 2M3OW 1O6WA 1PINA 5E66A 1K9QA 2Y8NB 1YW5A 5E5WA 3M7NA 3NTPA 3TCZA 2ZAJA 2XP5A 4E5RA 3M85A 1TK7A 2BA1A 2ZQUA 1EG4A 1I5HW 3MQHA 1EG3A 4U86A 5E62A 1WR7A 3OOBA 2OWOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3TDB A;  2XP6 A;  2YSF A;  4U85 A;  2XPB A;  2JXW A;  2L4J A;  2XPA A;  2ZQV A;  3ODK A;  2YSG A;  2ZQT A;  3L4H A;  2JX8 A;  2ZR4 A;  4REX A;  2DMV A;  2ZR5 A;  2XP8 A;  3WH0 A;  2DWV A;  3KCE A;  3KAF A;  2XP4 A;  1NMV A;  2YSI A;  2RE3 A;  3KAG A;  2LAJ A;  2MDI A;  2F21 A;  2Q5A A;  2E45 A;  2KXQ A;  1WMV A;  3CNG A;  3KAH A;  3KAI A;  3LE4 A;  2XP3 A;  3KAB A;  4QIB A;  2DJY A;  5CQ2 A;  2M8I A;  2JV4 A;  3TC5 A;  3KAD A;  2ITK A;  2M8J A;  2YSH A;  2XP7 A;  2JMF A;  1ZCN A;  4U84 A;  1F8A B;  2DK1 A;  2XP9 A;  2ZQS A;  1K9R A;  1JMQ A;  2EZ5 W;  5AHT A;  2YSB A;  2ZR6 A;  2DK7 A;  2M3O W;  1PIN A;  1O6W A;  1K9Q A;  1YW5 A;  3M7N A;  3NTP A;  3TCZ A;  2ZAJ A;  2XP5 A;  4E5R A;  3M85 A;  1TK7 A;  2BA1 A;  2ZQU A;  1EG4 A;  1I5H W;  1EG3 A;  4U86 A;  1WR7 A;  3OOB A; 
#chains in the Genus database with same CATH topology
 3TDB A;  5E65 A;  2WAD A;  1TR8 A;  2XP6 A;  2YSF A;  4U85 A;  2XPB A;  1FLC A;  4GLX A;  3FS8 A;  2JXW A;  2L4J A;  2YAJ B;  2XPA A;  2ZQV A;  3LKX B;  3ODK A;  2YSG A;  2ZQT A;  3L4H A;  2JX8 A;  2ZR4 A;  4REX A;  2DMV A;  2ZR5 A;  3PQH A;  3MCB A;  2XP8 A;  3WH0 A;  2DWV A;  2QRV A;  3KCE A;  3KAF A;  2XP4 A;  1NMV A;  2YSI A;  2RE3 A;  3KAG A;  2LAJ A;  2MDI A;  2F21 A;  2Q5A A;  2E45 A;  2KXQ A;  1WMV A;  3CNG A;  3FSC A;  3KAH A;  3KAI A;  5E64 A;  3LE4 A;  2XP3 A;  3KAB A;  4QIB A;  2DJY A;  4A0T A;  5CQ2 A;  5U47 A;  2M8I A;  2JV4 A;  3TC5 A;  3KAD A;  2ITK A;  2M8J A;  1RP5 A;  2YSH A;  2XP7 A;  2JMF A;  1ZCN A;  4A0U A;  4U84 A;  1F8A B;  3MCB B;  3LKX A;  2DK1 A;  2XP9 A;  2WAE A;  2ZQS A;  1K9R A;  1JMQ A;  2EZ5 W;  5AHT A;  3MQG A;  2YSB A;  2ZR6 A;  2DK7 A;  3FSB A;  2M3O W;  1O6W A;  1PIN A;  5E66 A;  1K9Q A;  2Y8N B;  1YW5 A;  5E5W A;  3M7N A;  3NTP A;  3TCZ A;  2ZAJ A;  2XP5 A;  4E5R A;  3M85 A;  1TK7 A;  2BA1 A;  2ZQU A;  1EG4 A;  1I5H W;  3MQH A;  1EG3 A;  4U86 A;  5E62 A;  1WR7 A;  3OOB A;  2OWO A; 
#chains in the Genus database with same CATH homology
 3TDB A;  5E65 A;  2WAD A;  1TR8 A;  2XP6 A;  2YSF A;  4U85 A;  2XPB A;  1FLC A;  4GLX A;  3FS8 A;  2JXW A;  2L4J A;  2YAJ B;  2XPA A;  2ZQV A;  3LKX B;  3ODK A;  2YSG A;  2ZQT A;  3L4H A;  2JX8 A;  2ZR4 A;  4REX A;  2DMV A;  2ZR5 A;  3PQH A;  3MCB A;  2XP8 A;  3WH0 A;  2DWV A;  2QRV A;  3KCE A;  3KAF A;  2XP4 A;  1NMV A;  2YSI A;  2RE3 A;  3KAG A;  2LAJ A;  2MDI A;  2F21 A;  2Q5A A;  2E45 A;  2KXQ A;  1WMV A;  3CNG A;  3FSC A;  3KAH A;  3KAI A;  5E64 A;  3LE4 A;  2XP3 A;  3KAB A;  4QIB A;  2DJY A;  4A0T A;  5CQ2 A;  5U47 A;  2M8I A;  2JV4 A;  3TC5 A;  3KAD A;  2ITK A;  2M8J A;  1RP5 A;  2YSH A;  2XP7 A;  2JMF A;  1ZCN A;  4A0U A;  4U84 A;  1F8A B;  3MCB B;  3LKX A;  2DK1 A;  2XP9 A;  2WAE A;  2ZQS A;  1K9R A;  1JMQ A;  2EZ5 W;  5AHT A;  3MQG A;  2YSB A;  2ZR6 A;  2DK7 A;  3FSB A;  2M3O W;  1O6W A;  1PIN A;  5E66 A;  1K9Q A;  2Y8N B;  1YW5 A;  5E5W A;  3M7N A;  3NTP A;  3TCZ A;  2ZAJ A;  2XP5 A;  4E5R A;  3M85 A;  1TK7 A;  2BA1 A;  2ZQU A;  1EG4 A;  1I5H W;  3MQH A;  1EG3 A;  4U86 A;  5E62 A;  1WR7 A;  3OOB A;  2OWO A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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