4E5RA

Crystal structure of frog dgcr8 dimerization domain
Total Genus 4
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
4
sequence length
56
structure length
56
Chain Sequence
PPTEPLPDGWIMTFHNSGLPVYLHRETRVVTWSRPYFLGTGSIRKHDPPISSIPCL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Dimerization and heme binding are conserved in amphibian and starfish homologues of the microRNA processing protein DGCR8.
pubmed doi rcsb
molecule tags Rna binding protein
source organism Xenopus laevis
molecule keywords MGC78846 protein
total genus 4
structure length 56
sequence length 56
ec nomenclature
pdb deposition date 2012-03-14
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.70.10 Mainly Beta Single Sheet Ubiquitin Ligase Nedd4; Chain: W; Ubiquitin Ligase Nedd4; Chain: W; 4e5rA00
1WMVA 3TC5A 3CNGA 2M3OW 2XP3A 2KXQA 2DJYA 3LE4A 2DMVA 2M8JA 2BA1A 2YSHA 3TCZA 2F21A 1K9QA 2XP9A 3TDBA 2JXWA 1WR7A 2ZR5A 3L4HA 3KADA 2DK7A 2XPBA 1K9RA 4U86A 2RE3A 2XP6A 2XP4A 2XP8A 3KCEA 2Q5AA 2ZQSA 2DK1A 4U85A 2ZQTA 3NTPA 3WH0A 1O6WA 2YSIA 3M7NA 2ZAJA 2JX8A 1NMVA 2ZR6A 1TK7A 3KAHA 2ITKA 2JMFA 1ZCNA 5CQ2A 3OOBA 2XP5A 3KAIA 3ODKA 2ZQVA 1JMQA 1F8AB 2LAJA 2XPAA 2MDIA 2JV4A 4QIBA 3M85A 2YSGA 3KABA 3KAGA 2EZ5W 4U84A 1I5HW 5AHTA 1EG4A 2L4JA 4E5RA 2M8IA 3KAFA 2E45A 1YW5A 2ZQUA 2YSBA 1EG3A 2DWVA 2YSFA 2XP7A 4REXA 2ZR4A 1PINA
chains in the Genus database with same CATH superfamily
1WMVA 3TC5A 3FSBA 3CNGA 2M3OW 5E64A 2XP3A 2KXQA 2DJYA 3LE4A 2DMVA 2YAJB 2M8JA 4GLXA 2BA1A 2YSHA 5E5WA 3TCZA 2F21A 3MCBA 2XP9A 3TDBA 1K9QA 2JXWA 1WR7A 5E66A 3MCBB 2ZR5A 4A0TA 3LKXB 3L4HA 3KADA 2DK7A 2Y8NB 2XPBA 1K9RA 4U86A 2RE3A 2XP6A 2XP4A 5U47A 2XP8A 3KCEA 2Q5AA 2ZQSA 2DK1A 3PQHA 4U85A 2ZQTA 3NTPA 3WH0A 2WADA 2WAEA 1O6WA 2YSIA 3M7NA 2ZAJA 3FS8A 2JX8A 1NMVA 2ZR6A 1TK7A 3KAHA 2ITKA 2JMFA 1TR8A 1ZCNA 2QRVA 5CQ2A 3MQHA 3OOBA 2XP5A 3KAIA 3ODKA 4A0UA 2ZQVA 1JMQA 1F8AB 2LAJA 2XPAA 2MDIA 2JV4A 4QIBA 3M85A 3FSCA 2YSGA 3KABA 3KAGA 2EZ5W 3MQGA 4U84A 1I5HW 1FLCA 5AHTA 1EG4A 2L4JA 4E5RA 2M8IA 3KAFA 2E45A 1YW5A 3LKXA 2OWOA 2ZQUA 2YSBA 1EG3A 5E62A 2DWVA 5E65A 1RP5A 2YSFA 2XP7A 4REXA 2ZR4A 1PINA
chains in the Genus database with same CATH topology
1WMVA 3TC5A 3FSBA 3CNGA 2M3OW 5E64A 2XP3A 2KXQA 2DJYA 3LE4A 2DMVA 2YAJB 2M8JA 4GLXA 2BA1A 2YSHA 5E5WA 3TCZA 2F21A 3MCBA 2XP9A 3TDBA 1K9QA 2JXWA 1WR7A 5E66A 3MCBB 2ZR5A 4A0TA 3LKXB 3L4HA 3KADA 2DK7A 2Y8NB 2XPBA 1K9RA 4U86A 2RE3A 2XP6A 2XP4A 5U47A 2XP8A 3KCEA 2Q5AA 2ZQSA 2DK1A 3PQHA 4U85A 2ZQTA 3NTPA 3WH0A 2WADA 2WAEA 1O6WA 2YSIA 3M7NA 2ZAJA 3FS8A 2JX8A 1NMVA 2ZR6A 1TK7A 3KAHA 2ITKA 2JMFA 1TR8A 1ZCNA 2QRVA 5CQ2A 3MQHA 3OOBA 2XP5A 3KAIA 3ODKA 4A0UA 2ZQVA 1JMQA 1F8AB 2LAJA 2XPAA 2MDIA 2JV4A 4QIBA 3M85A 3FSCA 2YSGA 3KABA 3KAGA 2EZ5W 3MQGA 4U84A 1I5HW 1FLCA 5AHTA 1EG4A 2L4JA 4E5RA 2M8IA 3KAFA 2E45A 1YW5A 3LKXA 2OWOA 2ZQUA 2YSBA 1EG3A 5E62A 2DWVA 5E65A 1RP5A 2YSFA 2XP7A 4REXA 2ZR4A 1PINA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1WMV A;  3TC5 A;  3CNG A;  2M3O W;  2XP3 A;  2KXQ A;  2DJY A;  3LE4 A;  2DMV A;  2M8J A;  2BA1 A;  2YSH A;  3TCZ A;  2F21 A;  1K9Q A;  2XP9 A;  3TDB A;  2JXW A;  1WR7 A;  2ZR5 A;  3L4H A;  3KAD A;  2DK7 A;  2XPB A;  1K9R A;  4U86 A;  2RE3 A;  2XP6 A;  2XP4 A;  2XP8 A;  3KCE A;  2Q5A A;  2ZQS A;  2DK1 A;  4U85 A;  2ZQT A;  3NTP A;  3WH0 A;  1O6W A;  2YSI A;  3M7N A;  2ZAJ A;  2JX8 A;  1NMV A;  2ZR6 A;  1TK7 A;  3KAH A;  2ITK A;  2JMF A;  1ZCN A;  5CQ2 A;  3OOB A;  2XP5 A;  3KAI A;  3ODK A;  2ZQV A;  1JMQ A;  1F8A B;  2LAJ A;  2XPA A;  2MDI A;  2JV4 A;  4QIB A;  3M85 A;  2YSG A;  3KAB A;  3KAG A;  2EZ5 W;  4U84 A;  1I5H W;  5AHT A;  1EG4 A;  2L4J A;  4E5R A;  2M8I A;  3KAF A;  2E45 A;  1YW5 A;  2ZQU A;  2YSB A;  1EG3 A;  2DWV A;  2YSF A;  2XP7 A;  4REX A;  2ZR4 A;  1PIN A; 
#chains in the Genus database with same CATH topology
 1WMV A;  3TC5 A;  3FSB A;  3CNG A;  2M3O W;  5E64 A;  2XP3 A;  2KXQ A;  2DJY A;  3LE4 A;  2DMV A;  2YAJ B;  2M8J A;  4GLX A;  2BA1 A;  2YSH A;  5E5W A;  3TCZ A;  2F21 A;  3MCB A;  2XP9 A;  3TDB A;  1K9Q A;  2JXW A;  1WR7 A;  5E66 A;  3MCB B;  2ZR5 A;  4A0T A;  3LKX B;  3L4H A;  3KAD A;  2DK7 A;  2Y8N B;  2XPB A;  1K9R A;  4U86 A;  2RE3 A;  2XP6 A;  2XP4 A;  5U47 A;  2XP8 A;  3KCE A;  2Q5A A;  2ZQS A;  2DK1 A;  3PQH A;  4U85 A;  2ZQT A;  3NTP A;  3WH0 A;  2WAD A;  2WAE A;  1O6W A;  2YSI A;  3M7N A;  2ZAJ A;  3FS8 A;  2JX8 A;  1NMV A;  2ZR6 A;  1TK7 A;  3KAH A;  2ITK A;  2JMF A;  1TR8 A;  1ZCN A;  2QRV A;  5CQ2 A;  3MQH A;  3OOB A;  2XP5 A;  3KAI A;  3ODK A;  4A0U A;  2ZQV A;  1JMQ A;  1F8A B;  2LAJ A;  2XPA A;  2MDI A;  2JV4 A;  4QIB A;  3M85 A;  3FSC A;  2YSG A;  3KAB A;  3KAG A;  2EZ5 W;  3MQG A;  4U84 A;  1I5H W;  1FLC A;  5AHT A;  1EG4 A;  2L4J A;  4E5R A;  2M8I A;  3KAF A;  2E45 A;  1YW5 A;  3LKX A;  2OWO A;  2ZQU A;  2YSB A;  1EG3 A;  5E62 A;  2DWV A;  5E65 A;  1RP5 A;  2YSF A;  2XP7 A;  4REX A;  2ZR4 A;  1PIN A; 
#chains in the Genus database with same CATH homology
 1WMV A;  3TC5 A;  3FSB A;  3CNG A;  2M3O W;  5E64 A;  2XP3 A;  2KXQ A;  2DJY A;  3LE4 A;  2DMV A;  2YAJ B;  2M8J A;  4GLX A;  2BA1 A;  2YSH A;  5E5W A;  3TCZ A;  2F21 A;  3MCB A;  2XP9 A;  3TDB A;  1K9Q A;  2JXW A;  1WR7 A;  5E66 A;  3MCB B;  2ZR5 A;  4A0T A;  3LKX B;  3L4H A;  3KAD A;  2DK7 A;  2Y8N B;  2XPB A;  1K9R A;  4U86 A;  2RE3 A;  2XP6 A;  2XP4 A;  5U47 A;  2XP8 A;  3KCE A;  2Q5A A;  2ZQS A;  2DK1 A;  3PQH A;  4U85 A;  2ZQT A;  3NTP A;  3WH0 A;  2WAD A;  2WAE A;  1O6W A;  2YSI A;  3M7N A;  2ZAJ A;  3FS8 A;  2JX8 A;  1NMV A;  2ZR6 A;  1TK7 A;  3KAH A;  2ITK A;  2JMF A;  1TR8 A;  1ZCN A;  2QRV A;  5CQ2 A;  3MQH A;  3OOB A;  2XP5 A;  3KAI A;  3ODK A;  4A0U A;  2ZQV A;  1JMQ A;  1F8A B;  2LAJ A;  2XPA A;  2MDI A;  2JV4 A;  4QIB A;  3M85 A;  3FSC A;  2YSG A;  3KAB A;  3KAG A;  2EZ5 W;  3MQG A;  4U84 A;  1I5H W;  1FLC A;  5AHT A;  1EG4 A;  2L4J A;  4E5R A;  2M8I A;  3KAF A;  2E45 A;  1YW5 A;  3LKX A;  2OWO A;  2ZQU A;  2YSB A;  1EG3 A;  5E62 A;  2DWV A;  5E65 A;  1RP5 A;  2YSF A;  2XP7 A;  4REX A;  2ZR4 A;  1PIN A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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