1LPKA

Crystal structure of fxa in complex with 125.
Total Genus 12
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
53
structure length
53
Chain Sequence
RKLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTLE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Design and Quantitative Structure-Activity relationship of 3-amidinobenzyl-1H-indole-2-carboxamides as potent, nonchiral, and selective inhibitors of blood coagulation factor Xa
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords Blood coagulation factor Xa
total genus 12
structure length 53
sequence length 53
ec nomenclature ec 3.4.21.6: Coagulation factor Xa.
pdb deposition date 2002-05-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00008 EGF EGF-like domain
A PF14670 FXa_inhibition Coagulation Factor Xa inhibitory site
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 1lpkA00
1RFNB 3KL6B 3U73A 2RNLA 1NFXB 2XC0L 1URKA 2WPKE 2WYGB 2WPHE 1IVOC 4BDXA 1YO8A 5JB8E 1TPGA 1IGZA 4RRXA 4M10A 2FD6A 4BXSA 3LIWB 3QMOA 2OYEP 1FE2A 2XC5L 5EGMB 1NPEB 3R05A 1KIGL 1JV2B 1K36A 5CISA 2H9EL 1CVWL 3CFWA 2K2SB 2Y5HL 5KIRA 5CKMA 3K9XA 2Q1JB 4YZUB 5F1AA 1IQEL 2BQ7A 2VWNL 3HO3A 1I0UA 5JVYA 1FJSL 4ZHAB 4X8UL 2VH6B 5COXA 5CKNA 2Y7XB 5F19A 4ZAEB 2M74A 2DDUA 3ASIA 3KQCL 1HAEA 3NJPC 4Y7BB 1EPJA 5I46L 1APQA 2KL7A 3HPTA 1L3YA 2MGRA 1WU1B 1APOA 1KSNB 3KCGL 1M1XB 1NFYB 4MMXB 1KLJL 3TGFA 5E8DA 2Y7ZB 1CCFA 1F0RB 2BQ6A 2P28B 1UZQA 2BOHA 1KLOA 3LC3B 2J95B 4BDWA 2TGFA 2UWLB 1P0SL 4RS0A 4Z0KB 3HS6A 1JL9A 2B7DL 5JBCE 1FFMA 4D0FA 1CX2A 1CEJA 1WHEA 3KK6A 2J4IB 2FLGA 2WPME 2ADXA 1OB1C 1LMJA 1HREA 2PHBB 2G00L 1G2MB 6COXA 1EGFA 2Y5FL 1DDXA 1IQFL 1IQNL 2RA0L 4MMYB 4D90A 4OTJA 2P26A 4Y6DB 2W3KB 3SOVA 5JW1A 1PGEA 2W86A 1YGCL 5L30L 1YUGA 4ZXXL 2BOKL 4BXWA 1J9CL 3FCSB 4YT6L 3EGFA 1ATEA 1NZIA 1CQEA 2BQWA 2VVVL 3KQBL 2W2NE 1IJQA 3DEMA 1F7EA 3PGHA 3LN0A 1HT8A 1LPKA 2J34B 4RRZA 2W3IB 1UZKA 1IGXA 3CS7L 4CUFA 1CVUA 4BTUA 4TGFA 5IKRA 3HO4A 1O5DL 2XBYL 5L2ZL 2UWPB 4JZDL 5L2YL 2EI7B 3NT1A 4XLWA 2GD4A 1EPGA 2Y38A 4X8TL 1K37A 4NGAL 1U67A 3LN1A 1Z6EL 3GCWE 1DQBA 5K0HB 4Z0LA 2P94L 2BOXA 3POYA 3F1SB 1B9WA 3LTGD 3KRKA 1IQJL 1C5MF 1KLIL 3NTGA 3N8WA 2D1JB 1DIYA 1YUFA 3U7UG 3SOBB 3NTBA 2EI8B 4NG9L 4M11A 3TH3L 2WG3C 1ADXA 3V64C 2J38B 5CKQA 4COXA 1LPZA 1JBUL 1EMNA 1QFKL 3C9AC 5IKQA 4RRWA 1UZJA 4FM5A 2XC4L 2MGPA 1A3PA 2WFXB 4XBMA 3SOQA 1W7XL 1IOEL 1DVAL 1LQDA 4Y71B 4ZH8B 3N8ZA 3HO5A 1MOXC 2PUQL 1G1RA 3TK5B 1NQLB 4D0EA 5KN5C 1PRHA 3KQDL 3OLUA 2J94B 2Y80B 1TOZA 1MQ5L 3CA7A 1EPIA 1ATAA 4ISIL 2OYUP 2P3TA 4OTYA 3SW2A 4CSYA 2VVUL 1XFEA 2PR3B 1G1TA 2WFTA 3ZYGA 3RR3A 4XL1A 4MMZB 3ZYIB 3N8YA 5JB9E 3GISX 1NT0A 4YT7L 2I9BA 2WPIE 1G1SA 1NFUB 2Y5GL 1V3XB 3N8XA 2FLRL 2MHPA 5JBAE 1Z6CA 1G1QA 4Y7AB 2XBWL 4C16A 5IKTA 4G1MB 1Q4GA 2XBXL 2VJ3A 4RRYA 1XKAL 3QH0A 1U8CB 2BOUA 2W2ME 3FBYA 4ZXYL 1HRFA 2K2TA 2EI6B 1HJ7A 2W26B 1PFXL 2CJIB 4ISHL 4NA9L 3Q7DA 4Z6AL 3ENSA 2BZ6L 2BO2A 2JKHL 1IQLL 4LMFA 3M37L 2J2UB 4JYUL 1EBVA 3TK6B 1NFWB 4AQTA 1HCGB 1FAXL 4PH9A 2UWOB 1YUKB 2P93L 1ZAQA 4E1GA 2YGPA 1EQGA 1ATBA 2KV4A 2RHPA 1XDTR 1UZPA 3N8VA 1IQKL 1ATDA 3ELAL 1G2LB 3KQEL 3HS5A 2WG4B 3M36L 3H5CB 3V65B 4CUDA 3IITB 2VWLL 1PXXA 1COUA 1IP0A 1L5GB 2KB9A 3BPSE 2WYJB 1MQ6L 2AYLA 1CCVA 3CENL 3QCWA 1F0SB 2P3FN 1EQHA 4A7IA 3MDLA 1FAKL 3BT2A 4JYVL 2Y82B 2XBVL 1EAIC 3ZYJB 1EPHA 2NPRA 1LPGA 3LC5B 2VVCK 2FLBL 2VH0B 1IQML 1HT5A 2F9BL 3GCXE 1HAFA 3IJEB 1P9JA 3HS7A 3MQEA 1EMOA 1F7MA 1HX2A 3TZIA 2WPJE 1W8BL 4O1ZA 1FSBA 3N8WB 4O02B 1DX5I 2BMGA 1N1IA 4Y79B 5JVZA 3LTFB 4X8VL 3LAQA 3TBDA 3BT1A 5IKVA 1EZQB 4Y76B 1TLEA 3FFGL 3F6UL 2W2QE 4BTTA 4JZEL 1XKBA 2W2OE 1SZBA 1IOXA 1AUTL 1X7AL 2FZZL 4JZFL 1GK5A 2P16L 5FDQA 1IQIL 1IQGL 4X8SL 2W2PE 4LORA 1WHFA 5JBBE 2WPLE 1IQHL 2VWOL 3P5BL 2YGOA 2I9AA 2P3UA 3OLTA 1FF7A 2P95L 1BF9A 2Y81B 4RUTA 3Q3KB 1PTHA 2VWMK 4BTIA 1N7DA 3N8YB 2P3FL 1HZ8A 4CUEA
chains in the Genus database with same CATH superfamily
1RFNB 3KL6B 3U73A 2RNLA 1NFXB 2XC0L 1URKA 2WPKE 2WYGB 2WPHE 1IVOC 4BDXA 1YO8A 5JB8E 1TPGA 1IGZA 4RRXA 4M10A 2FD6A 4BXSA 3LIWB 3QMOA 1LMMA 2OYEP 1FE2A 2XC5L 5EGMB 1NPEB 3R05A 1KIGL 1JV2B 1K36A 5CISA 2H9EL 1CVWL 3CFWA 2Y5HL 2K2SB 5KIRA 5CKMA 3K9XA 2Q1JB 2JJLA 4YZUB 5F1AA 1IQEL 2BQ7A 2VWNL 3HO3A 1I0UA 5JVYA 1FJSL 4ZHAB 4X8UL 2VH6B 5COXA 5CKNA 2Y7XB 5F19A 4ZAEB 2VRSA 2M74A 2DDUA 3ASIA 3KQCL 1HAEA 3NJPC 4Y7BB 1EPJA 5I46L 1APQA 2KL7A 3HPTA 1L3YA 2HORA 2MGRA 1WU1B 1APOA 1KSNB 3KCGL 1M1XB 1NFYB 4MMXB 1KLJL 3TGFA 5E8DA 2Y7ZB 1CCFA 1F0RB 2BQ6A 2P28B 1UZQA 2BOHA 1KLOA 3LC3B 2J95B 4BDWA 2TGFA 2UWLB 1P0SL 4RS0A 4Z0KB 3HS6A 1JL9A 2B7DL 5JBCE 1FFMA 4D0FA 1CX2A 1CEJA 1WHEA 3KK6A 2J4IB 2FLGA 2WPME 2ADXA 1OB1C 1V1IA 1LMJA 3S6XA 1HREA 2PHBB 2G00L 1G2MB 6COXA 1EGFA 2Y5FL 1DDXA 1IQFL 1IQNL 2RA0L 4MMYB 4D90A 4OTJA 2P26A 4Y6DB 2W3KB 3SOVA 5JW1A 1PGEA 2W86A 1YGCL 5L30L 1YUGA 2KNIA 4ZXXL 2BOKL 4BXWA 1J9CL 3FCSB 4YT6L 3EGFA 1ATEA 1NZIA 1CQEA 2BQWA 2VVVL 3KQBL 2W2NE 1IJQA 3DEMA 1F7EA 2HOXA 3PGHA 3LN0A 1HT8A 1LPKA 2J34B 4RRZA 2W3IB 1UZKA 1IGXA 3CS7L 4CUFA 1CVUA 4BTUA 4TGFA 5IKRA 3HO4A 1O5DL 2XBYL 5L2ZL 2UWPB 4JZDL 5L2YL 2EI7B 3NT1A 4XLWA 2GD4A 1EPGA 2Y38A 4X8TL 1K37A 4NGAL 1U67A 1V1HA 1Z6EL 3LN1A 4A94C 3GCWE 4GU4A 1DQBA 5K0HB 4Z0LA 2P94L 2BOXA 3POYA 3F1SB 1B9WA 3LTGD 3KRKA 1IQJL 1C5MF 1KLIL 3NTGA 3N8WA 2D1JB 1DIYA 1YUFA 3U7UG 3SOBB 3NTBA 2EI8B 4NG9L 4M11A 3TH3L 2WG3C 1ADXA 3V64C 2J38B 5CKQA 4COXA 1LPZA 1JBUL 2BSFA 1EMNA 1QFKL 3C9AC 5IKQA 4RRWA 1QIUA 1UZJA 4FM5A 2XC4L 2MGPA 1A3PA 2WFXB 4XBMA 3SOQA 1W7XL 1IOEL 1DVAL 1LQDA 2WZPP 4Y71B 4ZH8B 3N8ZA 3HO5A 1MOXC 2PUQL 1G1RA 3TK5B 1NQLB 4D0EA 5KN5C 1PRHA 3KQDL 3OLUA 2J94B 2Y80B 1TOZA 1MQ5L 3CA7A 1EPIA 1ATAA 4ISIL 2OYUP 2P3TA 4OTYA 3SW2A 4CSYA 2VVUL 1XFEA 2PR3B 1G1TA 2WFTA 3ZYGA 3RR3A 4XL1A 4MMZB 3ZYIB 3N8YA 5JB9E 3GISX 1NT0A 4YT7L 2I9BA 2WPIE 1G1SA 1NFUB 2Y5GL 1V3XB 3N8XA 2FLRL 1LK9A 2MHPA 5JBAE 1Z6CA 1G1QA 4Y7AB 2XBWL 4C16A 5IKTA 4G1MB 1Q4GA 2XBXL 2VJ3A 4RRYA 1XKAL 3QH0A 1U8CB 2BOUA 2W2ME 3FBYA 4ZXYL 1HRFA 2K2TA 2EI6B 1HJ7A 2W26B 1PFXL 2CJIB 4ISHL 4NA9L 3Q7DA 4Z6AL 3ENSA 2BZ6L 2BO2A 2JKHL 1IQLL 4LMFA 3M37L 2J2UB 4JYUL 1EBVA 2BT7A 3TK6B 1NFWB 4AQTA 1HCGB 1FAXL 4PH9A 2UWOB 1YUKB 2P93L 1ZAQA 4E1GA 2YGPA 1EQGA 1ATBA 2KV4A 2RHPA 1XDTR 1UZPA 3N8VA 1IQKL 1ATDA 3ELAL 1G2LB 3KQEL 3HS5A 2WG4B 3M36L 2BT8A 3H5CB 3V65B 4CUDA 3IITB 2VWLL 1PXXA 1COUA 1IP0A 1L5GB 4GU3A 2KB9A 3BPSE 2WYJB 1MQ6L 2AYLA 1CCVA 3CENL 3QCWA 1F0SB 2P3FN 1EQHA 4A7IA 3MDLA 1FAKL 3BT2A 4JYVL 2Y82B 2XBVL 1EAIC 3ZYJB 1EPHA 2NPRA 1LPGA 3LC5B 2VVCK 2FLBL 2VH0B 1IQML 1HT5A 2F9BL 3GCXE 1HAFA 3IJEB 1P9JA 3HS7A 3MQEA 1EMOA 1F7MA 1HX2A 3TZIA 2WPJE 1W8BL 4O1ZA 1FSBA 3N8WB 4O02B 1DX5I 2BMGA 1N1IA 4Y79B 5JVZA 3LTFB 4X8VL 3LAQA 3TBDA 3BT1A 5IKVA 1EZQB 4Y76B 1TLEA 3FFGL 3F6UL 2W2QE 2H9EC 4BTTA 4JZEL 2YGQA 1XKBA 2W2OE 1KKEA 1SZBA 1IOXA 1AUTL 1X7AL 2FZZL 4JZFL 1GK5A 2P16L 5FDQA 1IQIL 1IQGL 4X8SL 2W2PE 4LORA 1WHFA 5JBBE 2WPLE 1IQHL 2VWOL 3P5BL 2YGOA 2I9AA 2P3UA 3OLTA 1FF7A 2P95L 1BF9A 2Y81B 4RUTA 3Q3KB 1PTHA 2VWMK 4BTIA 1N7DA 3N8YB 2P3FL 1HZ8A 4CUEA
chains in the Genus database with same CATH topology
1RFNB 3KL6B 3U73A 2RNLA 1NFXB 2XC0L 1URKA 2WPKE 2WYGB 2WPHE 1IVOC 4BDXA 1YO8A 5JB8E 1TPGA 1IGZA 4RRXA 4M10A 2FD6A 4BXSA 3LIWB 3QMOA 1LMMA 2OYEP 1FE2A 2XC5L 5EGMB 1NPEB 3R05A 1KIGL 1JV2B 1K36A 5CISA 2H9EL 1CVWL 3CFWA 2K2SB 2Y5HL 5KIRA 5CKMA 3K9XA 2Q1JB 4YZUB 5F1AA 1IQEL 2BQ7A 2VWNL 3HO3A 1I0UA 5JVYA 1FJSL 4ZHAB 4X8UL 2VH6B 5COXA 5CKNA 2Y7XB 5F19A 4ZAEB 2M74A 2DDUA 3ASIA 3KQCL 1HAEA 3NJPC 4Y7BB 1EPJA 5I46L 1APQA 2KL7A 3HPTA 1L3YA 2MGRA 1WU1B 1APOA 1KSNB 3KCGL 1M1XB 1NFYB 4MMXB 1KLJL 3TGFA 5E8DA 2Y7ZB 1CCFA 1F0RB 2BQ6A 2P28B 1UZQA 2BOHA 1KLOA 3LC3B 2J95B 4BDWA 2TGFA 2UWLB 1P0SL 4RS0A 4Z0KB 3HS6A 1JL9A 2B7DL 5JBCE 1FFMA 4D0FA 1CX2A 1CEJA 1WHEA 3KK6A 2J4IB 2FLGA 2WPME 2ADXA 1OB1C 1LMJA 3S6XA 1HREA 2PHBB 2G00L 1G2MB 6COXA 1EGFA 2Y5FL 1DDXA 1IQFL 1IQNL 2RA0L 4MMYB 4D90A 4OTJA 2P26A 4Y6DB 2W3KB 3SOVA 5JW1A 1PGEA 2W86A 1YGCL 5L30L 1YUGA 2KNIA 4ZXXL 2BOKL 4BXWA 1J9CL 3FCSB 4YT6L 3EGFA 1ATEA 1NZIA 1CQEA 2BQWA 2VVVL 3KQBL 2W2NE 1IJQA 3DEMA 1F7EA 3PGHA 3LN0A 1HT8A 1LPKA 2J34B 4RRZA 2W3IB 1UZKA 1IGXA 3CS7L 4CUFA 1CVUA 4BTUA 4TGFA 5IKRA 3HO4A 1O5DL 2XBYL 5L2ZL 2UWPB 4JZDL 5L2YL 2EI7B 3NT1A 4XLWA 2GD4A 1EPGA 2Y38A 4X8TL 1K37A 4NGAL 1U67A 3LN1A 1Z6EL 4A94C 3GCWE 1DQBA 5K0HB 4Z0LA 2P94L 2BOXA 3POYA 3F1SB 1B9WA 3LTGD 3KRKA 1IQJL 1C5MF 1KLIL 3NTGA 3N8WA 2D1JB 1DIYA 1YUFA 3U7UG 3SOBB 3NTBA 2EI8B 4NG9L 4M11A 3TH3L 2WG3C 1ADXA 3V64C 2J38B 5CKQA 4COXA 1LPZA 1JBUL 1EMNA 1QFKL 3C9AC 5IKQA 4RRWA 1UZJA 4FM5A 2XC4L 2MGPA 1A3PA 2WFXB 4XBMA 3SOQA 1W7XL 1IOEL 1DVAL 1LQDA 2WZPP 4Y71B 4ZH8B 3N8ZA 3HO5A 1MOXC 2PUQL 1G1RA 3TK5B 1NQLB 4D0EA 5KN5C 1PRHA 3KQDL 3OLUA 2J94B 2Y80B 1TOZA 1MQ5L 3CA7A 1EPIA 1ATAA 4ISIL 2OYUP 2P3TA 4OTYA 3SW2A 4CSYA 2VVUL 1XFEA 2PR3B 1G1TA 2WFTA 3ZYGA 3RR3A 4XL1A 4MMZB 3ZYIB 3N8YA 5JB9E 3GISX 1NT0A 4YT7L 2I9BA 2WPIE 1G1SA 1NFUB 2Y5GL 1V3XB 3N8XA 2FLRL 2MHPA 5JBAE 1Z6CA 1G1QA 4Y7AB 2XBWL 4C16A 5IKTA 4G1MB 1Q4GA 2XBXL 2VJ3A 4RRYA 1XKAL 3QH0A 1U8CB 2BOUA 2W2ME 3FBYA 4ZXYL 1HRFA 2K2TA 2EI6B 1HJ7A 2W26B 1PFXL 2CJIB 4ISHL 4NA9L 3Q7DA 4Z6AL 3ENSA 2BZ6L 2BO2A 2JKHL 1IQLL 4LMFA 3M37L 2J2UB 4JYUL 1EBVA 3TK6B 1NFWB 4AQTA 1HCGB 1FAXL 4PH9A 2UWOB 1YUKB 2P93L 1ZAQA 4E1GA 2YGPA 1EQGA 1ATBA 2KV4A 2RHPA 1XDTR 1UZPA 3N8VA 1IQKL 1ATDA 3ELAL 1G2LB 3KQEL 3HS5A 2WG4B 3M36L 3H5CB 3V65B 4CUDA 3IITB 2VWLL 1PXXA 1COUA 1IP0A 1L5GB 2KB9A 3BPSE 2WYJB 1MQ6L 2AYLA 1CCVA 3CENL 3QCWA 1F0SB 2P3FN 1EQHA 4A7IA 3MDLA 1FAKL 3BT2A 4JYVL 2Y82B 2XBVL 1EAIC 3ZYJB 1EPHA 2NPRA 1LPGA 3LC5B 2VVCK 2FLBL 2VH0B 1IQML 1HT5A 2F9BL 3GCXE 1HAFA 3IJEB 1P9JA 3HS7A 3MQEA 1EMOA 1F7MA 1HX2A 3TZIA 2WPJE 1W8BL 4O1ZA 1FSBA 3N8WB 4O02B 1DX5I 2BMGA 1N1IA 4Y79B 5JVZA 3LTFB 4X8VL 3LAQA 3TBDA 3BT1A 5IKVA 1EZQB 4Y76B 1TLEA 3FFGL 3F6UL 2W2QE 2H9EC 4BTTA 4JZEL 2YGQA 1XKBA 2W2OE 1SZBA 1IOXA 1AUTL 1X7AL 2FZZL 4JZFL 1GK5A 2P16L 5FDQA 1IQIL 1IQGL 4X8SL 2W2PE 4LORA 1WHFA 5JBBE 2WPLE 1IQHL 2VWOL 3P5BL 2YGOA 2I9AA 2P3UA 3OLTA 1FF7A 2P95L 1BF9A 2Y81B 4RUTA 3Q3KB 1PTHA 2VWMK 4BTIA 1N7DA 3N8YB 2P3FL 1HZ8A 4CUEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1RFN B;  3KL6 B;  3U73 A;  2RNL A;  1NFX B;  2XC0 L;  1URK A;  2WPK E;  2WYG B;  2WPH E;  1IVO C;  4BDX A;  1YO8 A;  5JB8 E;  1TPG A;  1IGZ A;  4RRX A;  4M10 A;  2FD6 A;  4BXS A;  3LIW B;  3QMO A;  2OYE P;  1FE2 A;  2XC5 L;  5EGM B;  1NPE B;  3R05 A;  1KIG L;  1JV2 B;  1K36 A;  5CIS A;  2H9E L;  1CVW L;  3CFW A;  2K2S B;  2Y5H L;  5KIR A;  5CKM A;  3K9X A;  2Q1J B;  4YZU B;  5F1A A;  1IQE L;  2BQ7 A;  2VWN L;  3HO3 A;  1I0U A;  5JVY A;  1FJS L;  4ZHA B;  4X8U L;  2VH6 B;  5COX A;  5CKN A;  2Y7X B;  5F19 A;  4ZAE B;  2M74 A;  2DDU A;  3ASI A;  3KQC L;  1HAE A;  3NJP C;  4Y7B B;  1EPJ A;  5I46 L;  1APQ A;  2KL7 A;  3HPT A;  1L3Y A;  2MGR A;  1WU1 B;  1APO A;  1KSN B;  3KCG L;  1M1X B;  1NFY B;  4MMX B;  1KLJ L;  3TGF A;  5E8D A;  2Y7Z B;  1CCF A;  1F0R B;  2BQ6 A;  2P28 B;  1UZQ A;  2BOH A;  1KLO A;  3LC3 B;  2J95 B;  4BDW A;  2TGF A;  2UWL B;  1P0S L;  4RS0 A;  4Z0K B;  3HS6 A;  1JL9 A;  2B7D L;  5JBC E;  1FFM A;  4D0F A;  1CX2 A;  1CEJ A;  1WHE A;  3KK6 A;  2J4I B;  2FLG A;  2WPM E;  2ADX A;  1OB1 C;  1LMJ A;  1HRE A;  2PHB B;  2G00 L;  1G2M B;  6COX A;  1EGF A;  2Y5F L;  1DDX A;  1IQF L;  1IQN L;  2RA0 L;  4MMY B;  4D90 A;  4OTJ A;  2P26 A;  4Y6D B;  2W3K B;  3SOV A;  5JW1 A;  1PGE A;  2W86 A;  1YGC L;  5L30 L;  1YUG A;  4ZXX L;  2BOK L;  4BXW A;  1J9C L;  3FCS B;  4YT6 L;  3EGF A;  1ATE A;  1NZI A;  1CQE A;  2BQW A;  2VVV L;  3KQB L;  2W2N E;  1IJQ A;  3DEM A;  1F7E A;  3PGH A;  3LN0 A;  1HT8 A;  1LPK A;  2J34 B;  4RRZ A;  2W3I B;  1UZK A;  1IGX A;  3CS7 L;  4CUF A;  1CVU A;  4BTU A;  4TGF A;  5IKR A;  3HO4 A;  1O5D L;  2XBY L;  5L2Z L;  2UWP B;  4JZD L;  5L2Y L;  2EI7 B;  3NT1 A;  4XLW A;  2GD4 A;  1EPG A;  2Y38 A;  4X8T L;  1K37 A;  4NGA L;  1U67 A;  3LN1 A;  1Z6E L;  3GCW E;  1DQB A;  5K0H B;  4Z0L A;  2P94 L;  2BOX A;  3POY A;  3F1S B;  1B9W A;  3LTG D;  3KRK A;  1IQJ L;  1C5M F;  1KLI L;  3NTG A;  3N8W A;  2D1J B;  1DIY A;  1YUF A;  3U7U G;  3SOB B;  3NTB A;  2EI8 B;  4NG9 L;  4M11 A;  3TH3 L;  2WG3 C;  1ADX A;  3V64 C;  2J38 B;  5CKQ A;  4COX A;  1LPZ A;  1JBU L;  1EMN A;  1QFK L;  3C9A C;  5IKQ A;  4RRW A;  1UZJ A;  4FM5 A;  2XC4 L;  2MGP A;  1A3P A;  2WFX B;  4XBM A;  3SOQ A;  1W7X L;  1IOE L;  1DVA L;  1LQD A;  4Y71 B;  4ZH8 B;  3N8Z A;  3HO5 A;  1MOX C;  2PUQ L;  1G1R A;  3TK5 B;  1NQL B;  4D0E A;  5KN5 C;  1PRH A;  3KQD L;  3OLU A;  2J94 B;  2Y80 B;  1TOZ A;  1MQ5 L;  3CA7 A;  1EPI A;  1ATA A;  4ISI L;  2OYU P;  2P3T A;  4OTY A;  3SW2 A;  4CSY A;  2VVU L;  1XFE A;  2PR3 B;  1G1T A;  2WFT A;  3ZYG A;  3RR3 A;  4XL1 A;  4MMZ B;  3ZYI B;  3N8Y A;  5JB9 E;  3GIS X;  1NT0 A;  4YT7 L;  2I9B A;  2WPI E;  1G1S A;  1NFU B;  2Y5G L;  1V3X B;  3N8X A;  2FLR L;  2MHP A;  5JBA E;  1Z6C A;  1G1Q A;  4Y7A B;  2XBW L;  4C16 A;  5IKT A;  4G1M B;  1Q4G A;  2XBX L;  2VJ3 A;  4RRY A;  1XKA L;  3QH0 A;  1U8C B;  2BOU A;  2W2M E;  3FBY A;  4ZXY L;  1HRF A;  2K2T A;  2EI6 B;  1HJ7 A;  2W26 B;  1PFX L;  2CJI B;  4ISH L;  4NA9 L;  3Q7D A;  4Z6A L;  3ENS A;  2BZ6 L;  2BO2 A;  2JKH L;  1IQL L;  4LMF A;  3M37 L;  2J2U B;  4JYU L;  1EBV A;  3TK6 B;  1NFW B;  4AQT A;  1HCG B;  1FAX L;  4PH9 A;  2UWO B;  1YUK B;  2P93 L;  1ZAQ A;  4E1G A;  2YGP A;  1EQG A;  1ATB A;  2KV4 A;  2RHP A;  1XDT R;  1UZP A;  3N8V A;  1IQK L;  1ATD A;  3ELA L;  1G2L B;  3KQE L;  3HS5 A;  2WG4 B;  3M36 L;  3H5C B;  3V65 B;  4CUD A;  3IIT B;  2VWL L;  1PXX A;  1COU A;  1IP0 A;  1L5G B;  2KB9 A;  3BPS E;  2WYJ B;  1MQ6 L;  2AYL A;  1CCV A;  3CEN L;  3QCW A;  1F0S B;  2P3F N;  1EQH A;  4A7I A;  3MDL A;  1FAK L;  3BT2 A;  4JYV L;  2Y82 B;  2XBV L;  1EAI C;  3ZYJ B;  1EPH A;  2NPR A;  1LPG A;  3LC5 B;  2VVC K;  2FLB L;  2VH0 B;  1IQM L;  1HT5 A;  2F9B L;  3GCX E;  1HAF A;  3IJE B;  1P9J A;  3HS7 A;  3MQE A;  1EMO A;  1F7M A;  1HX2 A;  3TZI A;  2WPJ E;  1W8B L;  4O1Z A;  1FSB A;  3N8W B;  4O02 B;  1DX5 I;  2BMG A;  1N1I A;  4Y79 B;  5JVZ A;  3LTF B;  4X8V L;  3LAQ A;  3TBD A;  3BT1 A;  5IKV A;  1EZQ B;  4Y76 B;  1TLE A;  3FFG L;  3F6U L;  2W2Q E;  4BTT A;  4JZE L;  1XKB A;  2W2O E;  1SZB A;  1IOX A;  1AUT L;  1X7A L;  2FZZ L;  4JZF L;  1GK5 A;  2P16 L;  5FDQ A;  1IQI L;  1IQG L;  4X8S L;  2W2P E;  4LOR A;  1WHF A;  5JBB E;  2WPL E;  1IQH L;  2VWO L;  3P5B L;  2YGO A;  2I9A A;  2P3U A;  3OLT A;  1FF7 A;  2P95 L;  1BF9 A;  2Y81 B;  4RUT A;  3Q3K B;  1PTH A;  2VWM K;  4BTI A;  1N7D A;  3N8Y B;  2P3F L;  1HZ8 A;  4CUE A; 
#chains in the Genus database with same CATH topology
 1RFN B;  3KL6 B;  3U73 A;  2RNL A;  1NFX B;  2XC0 L;  1URK A;  2WPK E;  2WYG B;  2WPH E;  1IVO C;  4BDX A;  1YO8 A;  5JB8 E;  1TPG A;  1IGZ A;  4RRX A;  4M10 A;  2FD6 A;  4BXS A;  3LIW B;  3QMO A;  1LMM A;  2OYE P;  1FE2 A;  2XC5 L;  5EGM B;  1NPE B;  3R05 A;  1KIG L;  1JV2 B;  1K36 A;  5CIS A;  2H9E L;  1CVW L;  3CFW A;  2Y5H L;  2K2S B;  5KIR A;  5CKM A;  3K9X A;  2Q1J B;  2JJL A;  4YZU B;  5F1A A;  1IQE L;  2BQ7 A;  2VWN L;  3HO3 A;  1I0U A;  5JVY A;  1FJS L;  4ZHA B;  4X8U L;  2VH6 B;  5COX A;  5CKN A;  2Y7X B;  5F19 A;  4ZAE B;  2VRS A;  2M74 A;  2DDU A;  3ASI A;  3KQC L;  1HAE A;  3NJP C;  4Y7B B;  1EPJ A;  5I46 L;  1APQ A;  2KL7 A;  3HPT A;  1L3Y A;  2HOR A;  2MGR A;  1WU1 B;  1APO A;  1KSN B;  3KCG L;  1M1X B;  1NFY B;  4MMX B;  1KLJ L;  3TGF A;  5E8D A;  2Y7Z B;  1CCF A;  1F0R B;  2BQ6 A;  2P28 B;  1UZQ A;  2BOH A;  1KLO A;  3LC3 B;  2J95 B;  4BDW A;  2TGF A;  2UWL B;  1P0S L;  4RS0 A;  4Z0K B;  3HS6 A;  1JL9 A;  2B7D L;  5JBC E;  1FFM A;  4D0F A;  1CX2 A;  1CEJ A;  1WHE A;  3KK6 A;  2J4I B;  2FLG A;  2WPM E;  2ADX A;  1OB1 C;  1V1I A;  1LMJ A;  3S6X A;  1HRE A;  2PHB B;  2G00 L;  1G2M B;  6COX A;  1EGF A;  2Y5F L;  1DDX A;  1IQF L;  1IQN L;  2RA0 L;  4MMY B;  4D90 A;  4OTJ A;  2P26 A;  4Y6D B;  2W3K B;  3SOV A;  5JW1 A;  1PGE A;  2W86 A;  1YGC L;  5L30 L;  1YUG A;  2KNI A;  4ZXX L;  2BOK L;  4BXW A;  1J9C L;  3FCS B;  4YT6 L;  3EGF A;  1ATE A;  1NZI A;  1CQE A;  2BQW A;  2VVV L;  3KQB L;  2W2N E;  1IJQ A;  3DEM A;  1F7E A;  2HOX A;  3PGH A;  3LN0 A;  1HT8 A;  1LPK A;  2J34 B;  4RRZ A;  2W3I B;  1UZK A;  1IGX A;  3CS7 L;  4CUF A;  1CVU A;  4BTU A;  4TGF A;  5IKR A;  3HO4 A;  1O5D L;  2XBY L;  5L2Z L;  2UWP B;  4JZD L;  5L2Y L;  2EI7 B;  3NT1 A;  4XLW A;  2GD4 A;  1EPG A;  2Y38 A;  4X8T L;  1K37 A;  4NGA L;  1U67 A;  1V1H A;  1Z6E L;  3LN1 A;  4A94 C;  3GCW E;  4GU4 A;  1DQB A;  5K0H B;  4Z0L A;  2P94 L;  2BOX A;  3POY A;  3F1S B;  1B9W A;  3LTG D;  3KRK A;  1IQJ L;  1C5M F;  1KLI L;  3NTG A;  3N8W A;  2D1J B;  1DIY A;  1YUF A;  3U7U G;  3SOB B;  3NTB A;  2EI8 B;  4NG9 L;  4M11 A;  3TH3 L;  2WG3 C;  1ADX A;  3V64 C;  2J38 B;  5CKQ A;  4COX A;  1LPZ A;  1JBU L;  2BSF A;  1EMN A;  1QFK L;  3C9A C;  5IKQ A;  4RRW A;  1QIU A;  1UZJ A;  4FM5 A;  2XC4 L;  2MGP A;  1A3P A;  2WFX B;  4XBM A;  3SOQ A;  1W7X L;  1IOE L;  1DVA L;  1LQD A;  2WZP P;  4Y71 B;  4ZH8 B;  3N8Z A;  3HO5 A;  1MOX C;  2PUQ L;  1G1R A;  3TK5 B;  1NQL B;  4D0E A;  5KN5 C;  1PRH A;  3KQD L;  3OLU A;  2J94 B;  2Y80 B;  1TOZ A;  1MQ5 L;  3CA7 A;  1EPI A;  1ATA A;  4ISI L;  2OYU P;  2P3T A;  4OTY A;  3SW2 A;  4CSY A;  2VVU L;  1XFE A;  2PR3 B;  1G1T A;  2WFT A;  3ZYG A;  3RR3 A;  4XL1 A;  4MMZ B;  3ZYI B;  3N8Y A;  5JB9 E;  3GIS X;  1NT0 A;  4YT7 L;  2I9B A;  2WPI E;  1G1S A;  1NFU B;  2Y5G L;  1V3X B;  3N8X A;  2FLR L;  1LK9 A;  2MHP A;  5JBA E;  1Z6C A;  1G1Q A;  4Y7A B;  2XBW L;  4C16 A;  5IKT A;  4G1M B;  1Q4G A;  2XBX L;  2VJ3 A;  4RRY A;  1XKA L;  3QH0 A;  1U8C B;  2BOU A;  2W2M E;  3FBY A;  4ZXY L;  1HRF A;  2K2T A;  2EI6 B;  1HJ7 A;  2W26 B;  1PFX L;  2CJI B;  4ISH L;  4NA9 L;  3Q7D A;  4Z6A L;  3ENS A;  2BZ6 L;  2BO2 A;  2JKH L;  1IQL L;  4LMF A;  3M37 L;  2J2U B;  4JYU L;  1EBV A;  2BT7 A;  3TK6 B;  1NFW B;  4AQT A;  1HCG B;  1FAX L;  4PH9 A;  2UWO B;  1YUK B;  2P93 L;  1ZAQ A;  4E1G A;  2YGP A;  1EQG A;  1ATB A;  2KV4 A;  2RHP A;  1XDT R;  1UZP A;  3N8V A;  1IQK L;  1ATD A;  3ELA L;  1G2L B;  3KQE L;  3HS5 A;  2WG4 B;  3M36 L;  2BT8 A;  3H5C B;  3V65 B;  4CUD A;  3IIT B;  2VWL L;  1PXX A;  1COU A;  1IP0 A;  1L5G B;  4GU3 A;  2KB9 A;  3BPS E;  2WYJ B;  1MQ6 L;  2AYL A;  1CCV A;  3CEN L;  3QCW A;  1F0S B;  2P3F N;  1EQH A;  4A7I A;  3MDL A;  1FAK L;  3BT2 A;  4JYV L;  2Y82 B;  2XBV L;  1EAI C;  3ZYJ B;  1EPH A;  2NPR A;  1LPG A;  3LC5 B;  2VVC K;  2FLB L;  2VH0 B;  1IQM L;  1HT5 A;  2F9B L;  3GCX E;  1HAF A;  3IJE B;  1P9J A;  3HS7 A;  3MQE A;  1EMO A;  1F7M A;  1HX2 A;  3TZI A;  2WPJ E;  1W8B L;  4O1Z A;  1FSB A;  3N8W B;  4O02 B;  1DX5 I;  2BMG A;  1N1I A;  4Y79 B;  5JVZ A;  3LTF B;  4X8V L;  3LAQ A;  3TBD A;  3BT1 A;  5IKV A;  1EZQ B;  4Y76 B;  1TLE A;  3FFG L;  3F6U L;  2W2Q E;  2H9E C;  4BTT A;  4JZE L;  2YGQ A;  1XKB A;  2W2O E;  1KKE A;  1SZB A;  1IOX A;  1AUT L;  1X7A L;  2FZZ L;  4JZF L;  1GK5 A;  2P16 L;  5FDQ A;  1IQI L;  1IQG L;  4X8S L;  2W2P E;  4LOR A;  1WHF A;  5JBB E;  2WPL E;  1IQH L;  2VWO L;  3P5B L;  2YGO A;  2I9A A;  2P3U A;  3OLT A;  1FF7 A;  2P95 L;  1BF9 A;  2Y81 B;  4RUT A;  3Q3K B;  1PTH A;  2VWM K;  4BTI A;  1N7D A;  3N8Y B;  2P3F L;  1HZ8 A;  4CUE A; 
#chains in the Genus database with same CATH homology
 1RFN B;  3KL6 B;  3U73 A;  2RNL A;  1NFX B;  2XC0 L;  1URK A;  2WPK E;  2WYG B;  2WPH E;  1IVO C;  4BDX A;  1YO8 A;  5JB8 E;  1TPG A;  1IGZ A;  4RRX A;  4M10 A;  2FD6 A;  4BXS A;  3LIW B;  3QMO A;  1LMM A;  2OYE P;  1FE2 A;  2XC5 L;  5EGM B;  1NPE B;  3R05 A;  1KIG L;  1JV2 B;  1K36 A;  5CIS A;  2H9E L;  1CVW L;  3CFW A;  2K2S B;  2Y5H L;  5KIR A;  5CKM A;  3K9X A;  2Q1J B;  4YZU B;  5F1A A;  1IQE L;  2BQ7 A;  2VWN L;  3HO3 A;  1I0U A;  5JVY A;  1FJS L;  4ZHA B;  4X8U L;  2VH6 B;  5COX A;  5CKN A;  2Y7X B;  5F19 A;  4ZAE B;  2M74 A;  2DDU A;  3ASI A;  3KQC L;  1HAE A;  3NJP C;  4Y7B B;  1EPJ A;  5I46 L;  1APQ A;  2KL7 A;  3HPT A;  1L3Y A;  2MGR A;  1WU1 B;  1APO A;  1KSN B;  3KCG L;  1M1X B;  1NFY B;  4MMX B;  1KLJ L;  3TGF A;  5E8D A;  2Y7Z B;  1CCF A;  1F0R B;  2BQ6 A;  2P28 B;  1UZQ A;  2BOH A;  1KLO A;  3LC3 B;  2J95 B;  4BDW A;  2TGF A;  2UWL B;  1P0S L;  4RS0 A;  4Z0K B;  3HS6 A;  1JL9 A;  2B7D L;  5JBC E;  1FFM A;  4D0F A;  1CX2 A;  1CEJ A;  1WHE A;  3KK6 A;  2J4I B;  2FLG A;  2WPM E;  2ADX A;  1OB1 C;  1LMJ A;  3S6X A;  1HRE A;  2PHB B;  2G00 L;  1G2M B;  6COX A;  1EGF A;  2Y5F L;  1DDX A;  1IQF L;  1IQN L;  2RA0 L;  4MMY B;  4D90 A;  4OTJ A;  2P26 A;  4Y6D B;  2W3K B;  3SOV A;  5JW1 A;  1PGE A;  2W86 A;  1YGC L;  5L30 L;  1YUG A;  2KNI A;  4ZXX L;  2BOK L;  4BXW A;  1J9C L;  3FCS B;  4YT6 L;  3EGF A;  1ATE A;  1NZI A;  1CQE A;  2BQW A;  2VVV L;  3KQB L;  2W2N E;  1IJQ A;  3DEM A;  1F7E A;  3PGH A;  3LN0 A;  1HT8 A;  1LPK A;  2J34 B;  4RRZ A;  2W3I B;  1UZK A;  1IGX A;  3CS7 L;  4CUF A;  1CVU A;  4BTU A;  4TGF A;  5IKR A;  3HO4 A;  1O5D L;  2XBY L;  5L2Z L;  2UWP B;  4JZD L;  5L2Y L;  2EI7 B;  3NT1 A;  4XLW A;  2GD4 A;  1EPG A;  2Y38 A;  4X8T L;  1K37 A;  4NGA L;  1U67 A;  3LN1 A;  1Z6E L;  4A94 C;  3GCW E;  1DQB A;  5K0H B;  4Z0L A;  2P94 L;  2BOX A;  3POY A;  3F1S B;  1B9W A;  3LTG D;  3KRK A;  1IQJ L;  1C5M F;  1KLI L;  3NTG A;  3N8W A;  2D1J B;  1DIY A;  1YUF A;  3U7U G;  3SOB B;  3NTB A;  2EI8 B;  4NG9 L;  4M11 A;  3TH3 L;  2WG3 C;  1ADX A;  3V64 C;  2J38 B;  5CKQ A;  4COX A;  1LPZ A;  1JBU L;  1EMN A;  1QFK L;  3C9A C;  5IKQ A;  4RRW A;  1UZJ A;  4FM5 A;  2XC4 L;  2MGP A;  1A3P A;  2WFX B;  4XBM A;  3SOQ A;  1W7X L;  1IOE L;  1DVA L;  1LQD A;  2WZP P;  4Y71 B;  4ZH8 B;  3N8Z A;  3HO5 A;  1MOX C;  2PUQ L;  1G1R A;  3TK5 B;  1NQL B;  4D0E A;  5KN5 C;  1PRH A;  3KQD L;  3OLU A;  2J94 B;  2Y80 B;  1TOZ A;  1MQ5 L;  3CA7 A;  1EPI A;  1ATA A;  4ISI L;  2OYU P;  2P3T A;  4OTY A;  3SW2 A;  4CSY A;  2VVU L;  1XFE A;  2PR3 B;  1G1T A;  2WFT A;  3ZYG A;  3RR3 A;  4XL1 A;  4MMZ B;  3ZYI B;  3N8Y A;  5JB9 E;  3GIS X;  1NT0 A;  4YT7 L;  2I9B A;  2WPI E;  1G1S A;  1NFU B;  2Y5G L;  1V3X B;  3N8X A;  2FLR L;  2MHP A;  5JBA E;  1Z6C A;  1G1Q A;  4Y7A B;  2XBW L;  4C16 A;  5IKT A;  4G1M B;  1Q4G A;  2XBX L;  2VJ3 A;  4RRY A;  1XKA L;  3QH0 A;  1U8C B;  2BOU A;  2W2M E;  3FBY A;  4ZXY L;  1HRF A;  2K2T A;  2EI6 B;  1HJ7 A;  2W26 B;  1PFX L;  2CJI B;  4ISH L;  4NA9 L;  3Q7D A;  4Z6A L;  3ENS A;  2BZ6 L;  2BO2 A;  2JKH L;  1IQL L;  4LMF A;  3M37 L;  2J2U B;  4JYU L;  1EBV A;  3TK6 B;  1NFW B;  4AQT A;  1HCG B;  1FAX L;  4PH9 A;  2UWO B;  1YUK B;  2P93 L;  1ZAQ A;  4E1G A;  2YGP A;  1EQG A;  1ATB A;  2KV4 A;  2RHP A;  1XDT R;  1UZP A;  3N8V A;  1IQK L;  1ATD A;  3ELA L;  1G2L B;  3KQE L;  3HS5 A;  2WG4 B;  3M36 L;  3H5C B;  3V65 B;  4CUD A;  3IIT B;  2VWL L;  1PXX A;  1COU A;  1IP0 A;  1L5G B;  2KB9 A;  3BPS E;  2WYJ B;  1MQ6 L;  2AYL A;  1CCV A;  3CEN L;  3QCW A;  1F0S B;  2P3F N;  1EQH A;  4A7I A;  3MDL A;  1FAK L;  3BT2 A;  4JYV L;  2Y82 B;  2XBV L;  1EAI C;  3ZYJ B;  1EPH A;  2NPR A;  1LPG A;  3LC5 B;  2VVC K;  2FLB L;  2VH0 B;  1IQM L;  1HT5 A;  2F9B L;  3GCX E;  1HAF A;  3IJE B;  1P9J A;  3HS7 A;  3MQE A;  1EMO A;  1F7M A;  1HX2 A;  3TZI A;  2WPJ E;  1W8B L;  4O1Z A;  1FSB A;  3N8W B;  4O02 B;  1DX5 I;  2BMG A;  1N1I A;  4Y79 B;  5JVZ A;  3LTF B;  4X8V L;  3LAQ A;  3TBD A;  3BT1 A;  5IKV A;  1EZQ B;  4Y76 B;  1TLE A;  3FFG L;  3F6U L;  2W2Q E;  2H9E C;  4BTT A;  4JZE L;  2YGQ A;  1XKB A;  2W2O E;  1SZB A;  1IOX A;  1AUT L;  1X7A L;  2FZZ L;  4JZF L;  1GK5 A;  2P16 L;  5FDQ A;  1IQI L;  1IQG L;  4X8S L;  2W2P E;  4LOR A;  1WHF A;  5JBB E;  2WPL E;  1IQH L;  2VWO L;  3P5B L;  2YGO A;  2I9A A;  2P3U A;  3OLT A;  1FF7 A;  2P95 L;  1BF9 A;  2Y81 B;  4RUT A;  3Q3K B;  1PTH A;  2VWM K;  4BTI A;  1N7D A;  3N8Y B;  2P3F L;  1HZ8 A;  4CUE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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