2P94L

Factor xa in complex with the inhibitor 3-chloro-n-((1r,2s)-2-(4-(2-oxopyridin-1(2h)-yl)benzamido)cyclohexyl)-1h-indole-6-carboxamide
Total Genus 13
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
13
sequence length
52
structure length
52
Chain Sequence
KLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTLE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title SAR and X-ray structures of enantiopure 1,2-cis-(1R,2S)-cyclopentyldiamine and cyclohexyldiamine derivatives as inhibitors of coagulation Factor Xa
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords Factor Xa
total genus 13
structure length 52
sequence length 52
ec nomenclature ec 3.4.21.6: Coagulation factor Xa.
pdb deposition date 2007-03-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF14670 FXa_inhibition Coagulation Factor Xa inhibitory site
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 2p94L00
2RNLA 3SOQA 1IQFL 3LC5B 1APOA 1IQJL 3GCWE 1L5GB 2WPLE 1K37A 3POYA 2EI6B 1NT0A 3LN0A 1W7XL 4TGFA 3TZIA 3RR3A 1DIYA 2JKHL 4PH9A 1EPIA 2Y5FL 4G1MB 5I46L 1ADXA 1TPGA 1ATDA 4ZXYL 4BDXA 4X8TL 3CFWA 3F6UL 4NGAL 2WFXB 4XL1A 4AQTA 2FLGA 1SZBA 1HCGB 4CUDA 2WPME 2BQWA 4X8VL 4CUEA 2VWLL 2Y5HL 2Y5GL 1EQHA 2Q1JB 3QMOA 4BDWA 4ZAEB 2OYEP 1NPEB 2VH0B 1KIGL 3ZYIB 2Y82B 2WPHE 1FAKL 1XKAL 3NT1A 3H5CB 5JW1A 2W2PE 2XBXL 3ZYJB 4BTTA 1NFXB 1I0UA 2BZ6L 4XLWA 2UWOB 1IOEL 1JV2B 4OTJA 1AUTL 4BXWA 2Y7XB 2P16L 1G2LB 5IKTA 4X8SL 3SOVA 1IGXA 1PRHA 3MQEA 5KN5C 1F7MA 2GD4A 4YZUB 1G1RA 1F7EA 3PGHA 4Y7BB 3NTGA 3TH3L 2EI7B 2CJIB 2W2ME 3V65B 1G1TA 5CKMA 5JBAE 1Z6EL 2VH6B 1IQEL 3KQDL 1F0SB 2Y81B 2ADXA 2W86A 4ZXXL 4RRZA 2TGFA 1DQBA 2W2NE 5JVYA 1CCFA 4XBMA 4LORA 1WHEA 2KL7A 2BMGA 4D0EA 4ISIL 5FDQA 5L2ZL 1NFWB 2Y38A 2K2TA 1CVUA 1CVWL 2PUQL 5COXA 4ZH8B 3KL6B 1HT5A 3FBYA 1HJ7A 5JBBE 3QH0A 2WPIE 3N8WA 1QFKL 1UZJA 3N8WB 1N1IA 1Q4GA 2XBVL 2VVUL 3LTFB 2KB9A 3LAQA 1KSNB 2MGRA 1FAXL 1LPZA 1RFNB 5L2YL 3ENSA 1ZAQA 3KK6A 4D90A 4ISHL 4JZFL 4BTIA 1X7AL 1IOXA 2H9EL 1MOXC 2P28B 1B9WA 1COUA 2WYJB 1PFXL 1EPHA 4X8UL 1F0RB 1FJSL 1IP0A 1PXXA 3NTBA 1WU1B 2W26B 2DDUA 1LPGA 3KQCL 1DX5I 1IGZA 3HO4A 1EBVA 3N8XA 4ZHAB 2VVCK 3CS7L 4RUTA 4JYVL 5JB9E 3Q7DA 2WG3C 2P3FL 2VVVL 4M11A 2YGPA 2J38B 4BTUA 2K2SB 4MMZB 3SOBB 3C9AC 2P93L 3Q3KB 5CKNA 2XBYL 3NJPC 4NA9L 3HS7A 3N8YB 1NQLB 2VWNL 2J34B 1XFEA 2J4IB 3GCXE 3M36L 3OLTA 4YT7L 2EI8B 1YO8A 5F1AA 3TBDA 1A3PA 2D1JB 1IVOC 1PGEA 2I9AA 3KCGL 4Z0LA 2UWPB 1U8CB 2BQ6A 3FFGL 1HZ8A 1U67A 1WHFA 1URKA 5CKQA 1DDXA 1LMJA 1NZIA 3LN1A 3BPSE 1CEJA 3TK5B 3N8YA 2P3FN 3K9XA 2P26A 3F1SB 1IJQA 5IKRA 1YUFA 1MQ6L 4Y7AB 1KLJL 1UZQA 3HPTA 1BF9A 4Y76B 2MGPA 3QCWA 3N8VA 1IQML 2BO2A 2G00L 4RRWA 1W8BL 3LC3B 4C16A 1HT8A 1TOZA 3KQEL 3ASIA 1IQGL 4COXA 4M10A 1EMOA 3IITB 5CISA 2VWOL 1FFMA 1MQ5L 2BOXA 4BXSA 1J9CL 2Y7ZB 3U7UG 2W3KB 1M1XB 2KV4A 2OYUP 1YGCL 5EGMB 1HAFA 3MDLA 1N7DA 1Z6CA 3OLUA 2P3UA 1XDTR 2FLRL 1FF7A 1HAEA 1GK5A 2J2UB 1YUKB 3BT1A 1HX2A 2AYLA 3HS5A 2XC4L 2VJ3A 2W2OE 1NFYB 1HREA 1EMNA 1DVAL 1YUGA 2Y80B 4NG9L 4CSYA 1NFUB 4RRYA 3HO3A 3ELAL 4OTYA 3CA7A 3IJEB 5L30L 2WG4B 1C5MF 2WPKE 3N8ZA 3U73A 3R05A 2BQ7A 4LMFA 3FCSB 2BOKL 2XBWL 1IQHL 1EGFA 1P0SL 4Y79B 3P5BL 1JBUL 1FE2A 2I9BA 1ATAA 1IQNL 1LQDA 4RRXA 5IKVA 3TK6B 4MMXB 2VWMK 1EQGA 2W2QE 1K36A 1CX2A 3V64C 2J94B 1ATBA 1IQKL 2NPRA 2RHPA 1V3XB 1UZKA 1G1SA 1P9JA 4JZEL 1PTHA 3TGFA 2P3TA 1KLIL 4Z6AL 2YGOA 4Z0KB 5JBCE 1CCVA 2BOHA 1CQEA 4A7IA 1XKBA 1HRFA 2RA0L 2M74A 2BOUA 1G2MB 2W3IB 3EGFA 3DEMA 6COXA 1EPGA 1IQIL 3LIWB 3M37L 5JVZA 4CUFA 3ZYGA 1KLOA 1O5DL 4Y6DB 2MHPA 2WFTA 1EPJA 1LPKA 1IQLL 4JYUL 3CENL 1L3YA 4YT6L 2UWLB 5KIRA 4E1GA 2FD6A 1EAIC 2J95B 4O02B 5IKQA 2B7DL 4RS0A 3BT2A 2F9BL 4O1ZA 2WPJE 2P94L 4MMYB 3GISX 1JL9A 3HS6A 2FZZL 3KRKA 2XC5L 2XC0L 1FSBA 1TLEA 2PHBB 1G1QA 4Y71B 3KQBL 2FLBL 2WYGB 1OB1C 5JB8E 1UZPA 1EZQB 3SW2A 2P95L 3HO5A 4JZDL 5F19A 5K0HB 2PR3B 5E8DA 4D0FA 1ATEA 4FM5A 1APQA 3LTGD
chains in the Genus database with same CATH superfamily
2RNLA 3SOQA 1IQFL 3LC5B 1APOA 1IQJL 3GCWE 2VRSA 1L5GB 2WPLE 1K37A 3POYA 2EI6B 1NT0A 3LN0A 1W7XL 4TGFA 3TZIA 3RR3A 1DIYA 2JKHL 4PH9A 1EPIA 2Y5FL 4G1MB 5I46L 1ADXA 1TPGA 1ATDA 4ZXYL 4BDXA 4X8TL 3CFWA 3F6UL 4NGAL 2WFXB 4XL1A 4AQTA 2FLGA 1SZBA 1HCGB 4CUDA 2WPME 2BQWA 4X8VL 4CUEA 2VWLL 2Y5HL 2Y5GL 1EQHA 2Q1JB 3QMOA 4BDWA 4ZAEB 2OYEP 1NPEB 2VH0B 1KIGL 3ZYIB 2Y82B 2WPHE 1FAKL 1XKAL 3NT1A 3H5CB 5JW1A 2W2PE 2XBXL 3ZYJB 4BTTA 1NFXB 1I0UA 2BZ6L 4XLWA 2UWOB 1IOEL 1JV2B 4OTJA 1AUTL 4BXWA 2BT8A 4A94C 2Y7XB 2P16L 1G2LB 5IKTA 4X8SL 3SOVA 1IGXA 1PRHA 4GU4A 3MQEA 5KN5C 1F7MA 2GD4A 4YZUB 1G1RA 1F7EA 3PGHA 4Y7BB 3NTGA 3TH3L 2EI7B 2CJIB 2W2ME 3V65B 1G1TA 5CKMA 5JBAE 1Z6EL 2VH6B 1IQEL 3KQDL 1F0SB 2Y81B 2ADXA 2W86A 4ZXXL 4RRZA 2TGFA 1DQBA 2W2NE 5JVYA 1CCFA 4XBMA 4LORA 1WHEA 2KL7A 2BMGA 4D0EA 4ISIL 5FDQA 5L2ZL 1NFWB 2Y38A 2K2TA 1CVUA 1CVWL 2PUQL 5COXA 4ZH8B 3KL6B 1HT5A 3FBYA 1HJ7A 5JBBE 1KKEA 3QH0A 2WPIE 3N8WA 1QFKL 1UZJA 3N8WB 1N1IA 1Q4GA 2XBVL 2VVUL 3LTFB 2KB9A 3LAQA 1KSNB 2MGRA 1FAXL 1LPZA 1RFNB 2YGQA 5L2YL 3ENSA 2BSFA 1ZAQA 3KK6A 4D90A 4ISHL 4JZFL 4BTIA 1X7AL 1IOXA 2H9EL 1MOXC 2P28B 1B9WA 1COUA 2WYJB 1PFXL 1EPHA 4X8UL 1F0RB 1FJSL 1IP0A 1PXXA 3NTBA 1WU1B 2W26B 2DDUA 1LPGA 3KQCL 1DX5I 1IGZA 3HO4A 1EBVA 3N8XA 4ZHAB 2VVCK 3CS7L 4RUTA 4JYVL 5JB9E 3Q7DA 2WG3C 2P3FL 2VVVL 4M11A 2YGPA 2J38B 4BTUA 2K2SB 4MMZB 3SOBB 3C9AC 2P93L 3Q3KB 5CKNA 2XBYL 3NJPC 4NA9L 3HS7A 3N8YB 1NQLB 2VWNL 2J34B 1XFEA 2J4IB 3GCXE 3M36L 3OLTA 4YT7L 2EI8B 1YO8A 5F1AA 3TBDA 1A3PA 2D1JB 2JJLA 1IVOC 1PGEA 2I9AA 3KCGL 4Z0LA 2UWPB 1U8CB 2BQ6A 3FFGL 1HZ8A 1U67A 1WHFA 1URKA 5CKQA 1DDXA 1LMJA 1NZIA 3LN1A 3BPSE 1CEJA 3TK5B 3N8YA 2P3FN 3K9XA 2P26A 3F1SB 1IJQA 5IKRA 1YUFA 1MQ6L 4Y7AB 1KLJL 1UZQA 3HPTA 1BF9A 4Y76B 2MGPA 3QCWA 3N8VA 2KNIA 1IQML 2BO2A 2G00L 4RRWA 1W8BL 3LC3B 4C16A 1HT8A 2BT7A 1TOZA 3KQEL 3ASIA 1IQGL 4COXA 4M10A 1EMOA 3IITB 1V1IA 1QIUA 5CISA 2VWOL 1FFMA 1MQ5L 2BOXA 4BXSA 1J9CL 2Y7ZB 3U7UG 2W3KB 1M1XB 2KV4A 2OYUP 1YGCL 5EGMB 1HAFA 3MDLA 1N7DA 1Z6CA 3OLUA 2P3UA 1XDTR 2FLRL 1FF7A 1HAEA 1GK5A 2J2UB 1YUKB 3BT1A 1HX2A 2AYLA 3HS5A 2XC4L 2VJ3A 2W2OE 1NFYB 1HREA 1EMNA 1DVAL 1YUGA 2Y80B 4NG9L 4CSYA 1NFUB 4RRYA 3HO3A 3ELAL 4OTYA 3CA7A 3IJEB 5L30L 2H9EC 2WG4B 1C5MF 2WPKE 3N8ZA 3U73A 1V1HA 3R05A 2BQ7A 2HOXA 4LMFA 3FCSB 2BOKL 2XBWL 1IQHL 1EGFA 1P0SL 4Y79B 3P5BL 1LK9A 1JBUL 1FE2A 2I9BA 1ATAA 1IQNL 1LQDA 4RRXA 5IKVA 3TK6B 4MMXB 2VWMK 1EQGA 2WZPP 2HORA 2W2QE 1K36A 1CX2A 3V64C 2J94B 1ATBA 1IQKL 2NPRA 2RHPA 1V3XB 1UZKA 1G1SA 1P9JA 4JZEL 1PTHA 3TGFA 2P3TA 1KLIL 4Z6AL 2YGOA 4Z0KB 4GU3A 5JBCE 1CCVA 2BOHA 1CQEA 4A7IA 1XKBA 1HRFA 2RA0L 2M74A 2BOUA 1G2MB 2W3IB 3EGFA 3DEMA 6COXA 1EPGA 1IQIL 3LIWB 3M37L 5JVZA 3S6XA 4CUFA 3ZYGA 1KLOA 1O5DL 4Y6DB 2MHPA 2WFTA 1EPJA 1LPKA 1IQLL 4JYUL 3CENL 1L3YA 4YT6L 2UWLB 1LMMA 5KIRA 4E1GA 2FD6A 1EAIC 2J95B 4O02B 5IKQA 2B7DL 4RS0A 3BT2A 2F9BL 4O1ZA 2WPJE 2P94L 4MMYB 3GISX 1JL9A 3HS6A 2FZZL 3KRKA 2XC5L 2XC0L 1FSBA 1TLEA 2PHBB 1G1QA 4Y71B 3KQBL 2FLBL 2WYGB 1OB1C 5JB8E 1UZPA 1EZQB 3SW2A 2P95L 3HO5A 4JZDL 5F19A 5K0HB 2PR3B 5E8DA 4D0FA 1ATEA 4FM5A 1APQA 3LTGD
chains in the Genus database with same CATH topology
2RNLA 3SOQA 1IQFL 3LC5B 1APOA 1IQJL 3GCWE 1L5GB 2WPLE 1K37A 3POYA 2EI6B 1NT0A 3LN0A 1W7XL 4TGFA 3TZIA 3RR3A 1DIYA 2JKHL 4PH9A 1EPIA 2Y5FL 4G1MB 5I46L 1ADXA 1TPGA 1ATDA 4ZXYL 4BDXA 4X8TL 3CFWA 3F6UL 4NGAL 2WFXB 4XL1A 4AQTA 2FLGA 1SZBA 1HCGB 4CUDA 2WPME 2BQWA 4X8VL 4CUEA 2VWLL 2Y5HL 2Y5GL 1EQHA 2Q1JB 3QMOA 4BDWA 4ZAEB 2OYEP 1NPEB 2VH0B 1KIGL 3ZYIB 2Y82B 2WPHE 1FAKL 1XKAL 3NT1A 3H5CB 5JW1A 2W2PE 2XBXL 3ZYJB 4BTTA 1NFXB 1I0UA 2BZ6L 4XLWA 2UWOB 1IOEL 1JV2B 4OTJA 1AUTL 4BXWA 4A94C 2Y7XB 2P16L 1G2LB 5IKTA 4X8SL 3SOVA 1IGXA 1PRHA 3MQEA 5KN5C 1F7MA 2GD4A 4YZUB 1G1RA 1F7EA 3PGHA 4Y7BB 3NTGA 3TH3L 2EI7B 2CJIB 2W2ME 3V65B 1G1TA 5CKMA 5JBAE 1Z6EL 2VH6B 1IQEL 3KQDL 1F0SB 2Y81B 2ADXA 2W86A 4ZXXL 4RRZA 2TGFA 1DQBA 2W2NE 5JVYA 1CCFA 4XBMA 4LORA 1WHEA 2KL7A 2BMGA 4D0EA 4ISIL 5FDQA 5L2ZL 1NFWB 2Y38A 2K2TA 1CVUA 1CVWL 2PUQL 5COXA 4ZH8B 3KL6B 1HT5A 3FBYA 1HJ7A 5JBBE 3QH0A 2WPIE 3N8WA 1QFKL 1UZJA 3N8WB 1N1IA 1Q4GA 2XBVL 2VVUL 3LTFB 2KB9A 3LAQA 1KSNB 2MGRA 1FAXL 1LPZA 1RFNB 2YGQA 5L2YL 3ENSA 1ZAQA 3KK6A 4D90A 4ISHL 4JZFL 4BTIA 1X7AL 1IOXA 2H9EL 1MOXC 2P28B 1B9WA 1COUA 2WYJB 1PFXL 1EPHA 4X8UL 1F0RB 1FJSL 1IP0A 1PXXA 3NTBA 1WU1B 2W26B 2DDUA 1LPGA 3KQCL 1DX5I 1IGZA 3HO4A 1EBVA 3N8XA 4ZHAB 2VVCK 3CS7L 4RUTA 4JYVL 5JB9E 3Q7DA 2WG3C 2P3FL 2VVVL 4M11A 2YGPA 2J38B 4BTUA 2K2SB 4MMZB 3SOBB 3C9AC 2P93L 3Q3KB 5CKNA 2XBYL 3NJPC 4NA9L 3HS7A 3N8YB 1NQLB 2VWNL 2J34B 1XFEA 2J4IB 3GCXE 3M36L 3OLTA 4YT7L 2EI8B 1YO8A 5F1AA 3TBDA 1A3PA 2D1JB 1IVOC 1PGEA 2I9AA 3KCGL 4Z0LA 2UWPB 1U8CB 2BQ6A 3FFGL 1HZ8A 1U67A 1WHFA 1URKA 5CKQA 1DDXA 1LMJA 1NZIA 3LN1A 3BPSE 1CEJA 3TK5B 3N8YA 2P3FN 3K9XA 2P26A 3F1SB 1IJQA 5IKRA 1YUFA 1MQ6L 4Y7AB 1KLJL 1UZQA 3HPTA 1BF9A 4Y76B 2MGPA 3QCWA 3N8VA 2KNIA 1IQML 2BO2A 2G00L 4RRWA 1W8BL 3LC3B 4C16A 1HT8A 1TOZA 3KQEL 3ASIA 1IQGL 4COXA 4M10A 1EMOA 3IITB 5CISA 2VWOL 1FFMA 1MQ5L 2BOXA 4BXSA 1J9CL 2Y7ZB 3U7UG 2W3KB 1M1XB 2KV4A 2OYUP 1YGCL 5EGMB 1HAFA 3MDLA 1N7DA 1Z6CA 3OLUA 2P3UA 1XDTR 2FLRL 1FF7A 1HAEA 1GK5A 2J2UB 1YUKB 3BT1A 1HX2A 2AYLA 3HS5A 2XC4L 2VJ3A 2W2OE 1NFYB 1HREA 1EMNA 1DVAL 1YUGA 2Y80B 4NG9L 4CSYA 1NFUB 4RRYA 3HO3A 3ELAL 4OTYA 3CA7A 3IJEB 5L30L 2H9EC 2WG4B 1C5MF 2WPKE 3N8ZA 3U73A 3R05A 2BQ7A 4LMFA 3FCSB 2BOKL 2XBWL 1IQHL 1EGFA 1P0SL 4Y79B 3P5BL 1JBUL 1FE2A 2I9BA 1ATAA 1IQNL 1LQDA 4RRXA 5IKVA 3TK6B 4MMXB 2VWMK 1EQGA 2WZPP 2W2QE 1K36A 1CX2A 3V64C 2J94B 1ATBA 1IQKL 2NPRA 2RHPA 1V3XB 1UZKA 1G1SA 1P9JA 4JZEL 1PTHA 3TGFA 2P3TA 1KLIL 4Z6AL 2YGOA 4Z0KB 5JBCE 1CCVA 2BOHA 1CQEA 4A7IA 1XKBA 1HRFA 2RA0L 2M74A 2BOUA 1G2MB 2W3IB 3EGFA 3DEMA 6COXA 1EPGA 1IQIL 3LIWB 3M37L 5JVZA 3S6XA 4CUFA 3ZYGA 1KLOA 1O5DL 4Y6DB 2MHPA 2WFTA 1EPJA 1LPKA 1IQLL 4JYUL 3CENL 1L3YA 4YT6L 2UWLB 1LMMA 5KIRA 4E1GA 2FD6A 1EAIC 2J95B 4O02B 5IKQA 2B7DL 4RS0A 3BT2A 2F9BL 4O1ZA 2WPJE 2P94L 4MMYB 3GISX 1JL9A 3HS6A 2FZZL 3KRKA 2XC5L 2XC0L 1FSBA 1TLEA 2PHBB 1G1QA 4Y71B 3KQBL 2FLBL 2WYGB 1OB1C 5JB8E 1UZPA 1EZQB 3SW2A 2P95L 3HO5A 4JZDL 5F19A 5K0HB 2PR3B 5E8DA 4D0FA 1ATEA 4FM5A 1APQA 3LTGD
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2RNL A;  3SOQ A;  1IQF L;  3LC5 B;  1APO A;  1IQJ L;  3GCW E;  1L5G B;  2WPL E;  1K37 A;  3POY A;  2EI6 B;  1NT0 A;  3LN0 A;  1W7X L;  4TGF A;  3TZI A;  3RR3 A;  1DIY A;  2JKH L;  4PH9 A;  1EPI A;  2Y5F L;  4G1M B;  5I46 L;  1ADX A;  1TPG A;  1ATD A;  4ZXY L;  4BDX A;  4X8T L;  3CFW A;  3F6U L;  4NGA L;  2WFX B;  4XL1 A;  4AQT A;  2FLG A;  1SZB A;  1HCG B;  4CUD A;  2WPM E;  2BQW A;  4X8V L;  4CUE A;  2VWL L;  2Y5H L;  2Y5G L;  1EQH A;  2Q1J B;  3QMO A;  4BDW A;  4ZAE B;  2OYE P;  1NPE B;  2VH0 B;  1KIG L;  3ZYI B;  2Y82 B;  2WPH E;  1FAK L;  1XKA L;  3NT1 A;  3H5C B;  5JW1 A;  2W2P E;  2XBX L;  3ZYJ B;  4BTT A;  1NFX B;  1I0U A;  2BZ6 L;  4XLW A;  2UWO B;  1IOE L;  1JV2 B;  4OTJ A;  1AUT L;  4BXW A;  2Y7X B;  2P16 L;  1G2L B;  5IKT A;  4X8S L;  3SOV A;  1IGX A;  1PRH A;  3MQE A;  5KN5 C;  1F7M A;  2GD4 A;  4YZU B;  1G1R A;  1F7E A;  3PGH A;  4Y7B B;  3NTG A;  3TH3 L;  2EI7 B;  2CJI B;  2W2M E;  3V65 B;  1G1T A;  5CKM A;  5JBA E;  1Z6E L;  2VH6 B;  1IQE L;  3KQD L;  1F0S B;  2Y81 B;  2ADX A;  2W86 A;  4ZXX L;  4RRZ A;  2TGF A;  1DQB A;  2W2N E;  5JVY A;  1CCF A;  4XBM A;  4LOR A;  1WHE A;  2KL7 A;  2BMG A;  4D0E A;  4ISI L;  5FDQ A;  5L2Z L;  1NFW B;  2Y38 A;  2K2T A;  1CVU A;  1CVW L;  2PUQ L;  5COX A;  4ZH8 B;  3KL6 B;  1HT5 A;  3FBY A;  1HJ7 A;  5JBB E;  3QH0 A;  2WPI E;  3N8W A;  1QFK L;  1UZJ A;  3N8W B;  1N1I A;  1Q4G A;  2XBV L;  2VVU L;  3LTF B;  2KB9 A;  3LAQ A;  1KSN B;  2MGR A;  1FAX L;  1LPZ A;  1RFN B;  5L2Y L;  3ENS A;  1ZAQ A;  3KK6 A;  4D90 A;  4ISH L;  4JZF L;  4BTI A;  1X7A L;  1IOX A;  2H9E L;  1MOX C;  2P28 B;  1B9W A;  1COU A;  2WYJ B;  1PFX L;  1EPH A;  4X8U L;  1F0R B;  1FJS L;  1IP0 A;  1PXX A;  3NTB A;  1WU1 B;  2W26 B;  2DDU A;  1LPG A;  3KQC L;  1DX5 I;  1IGZ A;  3HO4 A;  1EBV A;  3N8X A;  4ZHA B;  2VVC K;  3CS7 L;  4RUT A;  4JYV L;  5JB9 E;  3Q7D A;  2WG3 C;  2P3F L;  2VVV L;  4M11 A;  2YGP A;  2J38 B;  4BTU A;  2K2S B;  4MMZ B;  3SOB B;  3C9A C;  2P93 L;  3Q3K B;  5CKN A;  2XBY L;  3NJP C;  4NA9 L;  3HS7 A;  3N8Y B;  1NQL B;  2VWN L;  2J34 B;  1XFE A;  2J4I B;  3GCX E;  3M36 L;  3OLT A;  4YT7 L;  2EI8 B;  1YO8 A;  5F1A A;  3TBD A;  1A3P A;  2D1J B;  1IVO C;  1PGE A;  2I9A A;  3KCG L;  4Z0L A;  2UWP B;  1U8C B;  2BQ6 A;  3FFG L;  1HZ8 A;  1U67 A;  1WHF A;  1URK A;  5CKQ A;  1DDX A;  1LMJ A;  1NZI A;  3LN1 A;  3BPS E;  1CEJ A;  3TK5 B;  3N8Y A;  2P3F N;  3K9X A;  2P26 A;  3F1S B;  1IJQ A;  5IKR A;  1YUF A;  1MQ6 L;  4Y7A B;  1KLJ L;  1UZQ A;  3HPT A;  1BF9 A;  4Y76 B;  2MGP A;  3QCW A;  3N8V A;  1IQM L;  2BO2 A;  2G00 L;  4RRW A;  1W8B L;  3LC3 B;  4C16 A;  1HT8 A;  1TOZ A;  3KQE L;  3ASI A;  1IQG L;  4COX A;  4M10 A;  1EMO A;  3IIT B;  5CIS A;  2VWO L;  1FFM A;  1MQ5 L;  2BOX A;  4BXS A;  1J9C L;  2Y7Z B;  3U7U G;  2W3K B;  1M1X B;  2KV4 A;  2OYU P;  1YGC L;  5EGM B;  1HAF A;  3MDL A;  1N7D A;  1Z6C A;  3OLU A;  2P3U A;  1XDT R;  2FLR L;  1FF7 A;  1HAE A;  1GK5 A;  2J2U B;  1YUK B;  3BT1 A;  1HX2 A;  2AYL A;  3HS5 A;  2XC4 L;  2VJ3 A;  2W2O E;  1NFY B;  1HRE A;  1EMN A;  1DVA L;  1YUG A;  2Y80 B;  4NG9 L;  4CSY A;  1NFU B;  4RRY A;  3HO3 A;  3ELA L;  4OTY A;  3CA7 A;  3IJE B;  5L30 L;  2WG4 B;  1C5M F;  2WPK E;  3N8Z A;  3U73 A;  3R05 A;  2BQ7 A;  4LMF A;  3FCS B;  2BOK L;  2XBW L;  1IQH L;  1EGF A;  1P0S L;  4Y79 B;  3P5B L;  1JBU L;  1FE2 A;  2I9B A;  1ATA A;  1IQN L;  1LQD A;  4RRX A;  5IKV A;  3TK6 B;  4MMX B;  2VWM K;  1EQG A;  2W2Q E;  1K36 A;  1CX2 A;  3V64 C;  2J94 B;  1ATB A;  1IQK L;  2NPR A;  2RHP A;  1V3X B;  1UZK A;  1G1S A;  1P9J A;  4JZE L;  1PTH A;  3TGF A;  2P3T A;  1KLI L;  4Z6A L;  2YGO A;  4Z0K B;  5JBC E;  1CCV A;  2BOH A;  1CQE A;  4A7I A;  1XKB A;  1HRF A;  2RA0 L;  2M74 A;  2BOU A;  1G2M B;  2W3I B;  3EGF A;  3DEM A;  6COX A;  1EPG A;  1IQI L;  3LIW B;  3M37 L;  5JVZ A;  4CUF A;  3ZYG A;  1KLO A;  1O5D L;  4Y6D B;  2MHP A;  2WFT A;  1EPJ A;  1LPK A;  1IQL L;  4JYU L;  3CEN L;  1L3Y A;  4YT6 L;  2UWL B;  5KIR A;  4E1G A;  2FD6 A;  1EAI C;  2J95 B;  4O02 B;  5IKQ A;  2B7D L;  4RS0 A;  3BT2 A;  2F9B L;  4O1Z A;  2WPJ E;  2P94 L;  4MMY B;  3GIS X;  1JL9 A;  3HS6 A;  2FZZ L;  3KRK A;  2XC5 L;  2XC0 L;  1FSB A;  1TLE A;  2PHB B;  1G1Q A;  4Y71 B;  3KQB L;  2FLB L;  2WYG B;  1OB1 C;  5JB8 E;  1UZP A;  1EZQ B;  3SW2 A;  2P95 L;  3HO5 A;  4JZD L;  5F19 A;  5K0H B;  2PR3 B;  5E8D A;  4D0F A;  1ATE A;  4FM5 A;  1APQ A;  3LTG D; 
#chains in the Genus database with same CATH topology
 2RNL A;  3SOQ A;  1IQF L;  3LC5 B;  1APO A;  1IQJ L;  3GCW E;  2VRS A;  1L5G B;  2WPL E;  1K37 A;  3POY A;  2EI6 B;  1NT0 A;  3LN0 A;  1W7X L;  4TGF A;  3TZI A;  3RR3 A;  1DIY A;  2JKH L;  4PH9 A;  1EPI A;  2Y5F L;  4G1M B;  5I46 L;  1ADX A;  1TPG A;  1ATD A;  4ZXY L;  4BDX A;  4X8T L;  3CFW A;  3F6U L;  4NGA L;  2WFX B;  4XL1 A;  4AQT A;  2FLG A;  1SZB A;  1HCG B;  4CUD A;  2WPM E;  2BQW A;  4X8V L;  4CUE A;  2VWL L;  2Y5H L;  2Y5G L;  1EQH A;  2Q1J B;  3QMO A;  4BDW A;  4ZAE B;  2OYE P;  1NPE B;  2VH0 B;  1KIG L;  3ZYI B;  2Y82 B;  2WPH E;  1FAK L;  1XKA L;  3NT1 A;  3H5C B;  5JW1 A;  2W2P E;  2XBX L;  3ZYJ B;  4BTT A;  1NFX B;  1I0U A;  2BZ6 L;  4XLW A;  2UWO B;  1IOE L;  1JV2 B;  4OTJ A;  1AUT L;  4BXW A;  2BT8 A;  4A94 C;  2Y7X B;  2P16 L;  1G2L B;  5IKT A;  4X8S L;  3SOV A;  1IGX A;  1PRH A;  4GU4 A;  3MQE A;  5KN5 C;  1F7M A;  2GD4 A;  4YZU B;  1G1R A;  1F7E A;  3PGH A;  4Y7B B;  3NTG A;  3TH3 L;  2EI7 B;  2CJI B;  2W2M E;  3V65 B;  1G1T A;  5CKM A;  5JBA E;  1Z6E L;  2VH6 B;  1IQE L;  3KQD L;  1F0S B;  2Y81 B;  2ADX A;  2W86 A;  4ZXX L;  4RRZ A;  2TGF A;  1DQB A;  2W2N E;  5JVY A;  1CCF A;  4XBM A;  4LOR A;  1WHE A;  2KL7 A;  2BMG A;  4D0E A;  4ISI L;  5FDQ A;  5L2Z L;  1NFW B;  2Y38 A;  2K2T A;  1CVU A;  1CVW L;  2PUQ L;  5COX A;  4ZH8 B;  3KL6 B;  1HT5 A;  3FBY A;  1HJ7 A;  5JBB E;  1KKE A;  3QH0 A;  2WPI E;  3N8W A;  1QFK L;  1UZJ A;  3N8W B;  1N1I A;  1Q4G A;  2XBV L;  2VVU L;  3LTF B;  2KB9 A;  3LAQ A;  1KSN B;  2MGR A;  1FAX L;  1LPZ A;  1RFN B;  2YGQ A;  5L2Y L;  3ENS A;  2BSF A;  1ZAQ A;  3KK6 A;  4D90 A;  4ISH L;  4JZF L;  4BTI A;  1X7A L;  1IOX A;  2H9E L;  1MOX C;  2P28 B;  1B9W A;  1COU A;  2WYJ B;  1PFX L;  1EPH A;  4X8U L;  1F0R B;  1FJS L;  1IP0 A;  1PXX A;  3NTB A;  1WU1 B;  2W26 B;  2DDU A;  1LPG A;  3KQC L;  1DX5 I;  1IGZ A;  3HO4 A;  1EBV A;  3N8X A;  4ZHA B;  2VVC K;  3CS7 L;  4RUT A;  4JYV L;  5JB9 E;  3Q7D A;  2WG3 C;  2P3F L;  2VVV L;  4M11 A;  2YGP A;  2J38 B;  4BTU A;  2K2S B;  4MMZ B;  3SOB B;  3C9A C;  2P93 L;  3Q3K B;  5CKN A;  2XBY L;  3NJP C;  4NA9 L;  3HS7 A;  3N8Y B;  1NQL B;  2VWN L;  2J34 B;  1XFE A;  2J4I B;  3GCX E;  3M36 L;  3OLT A;  4YT7 L;  2EI8 B;  1YO8 A;  5F1A A;  3TBD A;  1A3P A;  2D1J B;  2JJL A;  1IVO C;  1PGE A;  2I9A A;  3KCG L;  4Z0L A;  2UWP B;  1U8C B;  2BQ6 A;  3FFG L;  1HZ8 A;  1U67 A;  1WHF A;  1URK A;  5CKQ A;  1DDX A;  1LMJ A;  1NZI A;  3LN1 A;  3BPS E;  1CEJ A;  3TK5 B;  3N8Y A;  2P3F N;  3K9X A;  2P26 A;  3F1S B;  1IJQ A;  5IKR A;  1YUF A;  1MQ6 L;  4Y7A B;  1KLJ L;  1UZQ A;  3HPT A;  1BF9 A;  4Y76 B;  2MGP A;  3QCW A;  3N8V A;  2KNI A;  1IQM L;  2BO2 A;  2G00 L;  4RRW A;  1W8B L;  3LC3 B;  4C16 A;  1HT8 A;  2BT7 A;  1TOZ A;  3KQE L;  3ASI A;  1IQG L;  4COX A;  4M10 A;  1EMO A;  3IIT B;  1V1I A;  1QIU A;  5CIS A;  2VWO L;  1FFM A;  1MQ5 L;  2BOX A;  4BXS A;  1J9C L;  2Y7Z B;  3U7U G;  2W3K B;  1M1X B;  2KV4 A;  2OYU P;  1YGC L;  5EGM B;  1HAF A;  3MDL A;  1N7D A;  1Z6C A;  3OLU A;  2P3U A;  1XDT R;  2FLR L;  1FF7 A;  1HAE A;  1GK5 A;  2J2U B;  1YUK B;  3BT1 A;  1HX2 A;  2AYL A;  3HS5 A;  2XC4 L;  2VJ3 A;  2W2O E;  1NFY B;  1HRE A;  1EMN A;  1DVA L;  1YUG A;  2Y80 B;  4NG9 L;  4CSY A;  1NFU B;  4RRY A;  3HO3 A;  3ELA L;  4OTY A;  3CA7 A;  3IJE B;  5L30 L;  2H9E C;  2WG4 B;  1C5M F;  2WPK E;  3N8Z A;  3U73 A;  1V1H A;  3R05 A;  2BQ7 A;  2HOX A;  4LMF A;  3FCS B;  2BOK L;  2XBW L;  1IQH L;  1EGF A;  1P0S L;  4Y79 B;  3P5B L;  1LK9 A;  1JBU L;  1FE2 A;  2I9B A;  1ATA A;  1IQN L;  1LQD A;  4RRX A;  5IKV A;  3TK6 B;  4MMX B;  2VWM K;  1EQG A;  2WZP P;  2HOR A;  2W2Q E;  1K36 A;  1CX2 A;  3V64 C;  2J94 B;  1ATB A;  1IQK L;  2NPR A;  2RHP A;  1V3X B;  1UZK A;  1G1S A;  1P9J A;  4JZE L;  1PTH A;  3TGF A;  2P3T A;  1KLI L;  4Z6A L;  2YGO A;  4Z0K B;  4GU3 A;  5JBC E;  1CCV A;  2BOH A;  1CQE A;  4A7I A;  1XKB A;  1HRF A;  2RA0 L;  2M74 A;  2BOU A;  1G2M B;  2W3I B;  3EGF A;  3DEM A;  6COX A;  1EPG A;  1IQI L;  3LIW B;  3M37 L;  5JVZ A;  3S6X A;  4CUF A;  3ZYG A;  1KLO A;  1O5D L;  4Y6D B;  2MHP A;  2WFT A;  1EPJ A;  1LPK A;  1IQL L;  4JYU L;  3CEN L;  1L3Y A;  4YT6 L;  2UWL B;  1LMM A;  5KIR A;  4E1G A;  2FD6 A;  1EAI C;  2J95 B;  4O02 B;  5IKQ A;  2B7D L;  4RS0 A;  3BT2 A;  2F9B L;  4O1Z A;  2WPJ E;  2P94 L;  4MMY B;  3GIS X;  1JL9 A;  3HS6 A;  2FZZ L;  3KRK A;  2XC5 L;  2XC0 L;  1FSB A;  1TLE A;  2PHB B;  1G1Q A;  4Y71 B;  3KQB L;  2FLB L;  2WYG B;  1OB1 C;  5JB8 E;  1UZP A;  1EZQ B;  3SW2 A;  2P95 L;  3HO5 A;  4JZD L;  5F19 A;  5K0H B;  2PR3 B;  5E8D A;  4D0F A;  1ATE A;  4FM5 A;  1APQ A;  3LTG D; 
#chains in the Genus database with same CATH homology
 2RNL A;  3SOQ A;  1IQF L;  3LC5 B;  1APO A;  1IQJ L;  3GCW E;  1L5G B;  2WPL E;  1K37 A;  3POY A;  2EI6 B;  1NT0 A;  3LN0 A;  1W7X L;  4TGF A;  3TZI A;  3RR3 A;  1DIY A;  2JKH L;  4PH9 A;  1EPI A;  2Y5F L;  4G1M B;  5I46 L;  1ADX A;  1TPG A;  1ATD A;  4ZXY L;  4BDX A;  4X8T L;  3CFW A;  3F6U L;  4NGA L;  2WFX B;  4XL1 A;  4AQT A;  2FLG A;  1SZB A;  1HCG B;  4CUD A;  2WPM E;  2BQW A;  4X8V L;  4CUE A;  2VWL L;  2Y5H L;  2Y5G L;  1EQH A;  2Q1J B;  3QMO A;  4BDW A;  4ZAE B;  2OYE P;  1NPE B;  2VH0 B;  1KIG L;  3ZYI B;  2Y82 B;  2WPH E;  1FAK L;  1XKA L;  3NT1 A;  3H5C B;  5JW1 A;  2W2P E;  2XBX L;  3ZYJ B;  4BTT A;  1NFX B;  1I0U A;  2BZ6 L;  4XLW A;  2UWO B;  1IOE L;  1JV2 B;  4OTJ A;  1AUT L;  4BXW A;  4A94 C;  2Y7X B;  2P16 L;  1G2L B;  5IKT A;  4X8S L;  3SOV A;  1IGX A;  1PRH A;  3MQE A;  5KN5 C;  1F7M A;  2GD4 A;  4YZU B;  1G1R A;  1F7E A;  3PGH A;  4Y7B B;  3NTG A;  3TH3 L;  2EI7 B;  2CJI B;  2W2M E;  3V65 B;  1G1T A;  5CKM A;  5JBA E;  1Z6E L;  2VH6 B;  1IQE L;  3KQD L;  1F0S B;  2Y81 B;  2ADX A;  2W86 A;  4ZXX L;  4RRZ A;  2TGF A;  1DQB A;  2W2N E;  5JVY A;  1CCF A;  4XBM A;  4LOR A;  1WHE A;  2KL7 A;  2BMG A;  4D0E A;  4ISI L;  5FDQ A;  5L2Z L;  1NFW B;  2Y38 A;  2K2T A;  1CVU A;  1CVW L;  2PUQ L;  5COX A;  4ZH8 B;  3KL6 B;  1HT5 A;  3FBY A;  1HJ7 A;  5JBB E;  3QH0 A;  2WPI E;  3N8W A;  1QFK L;  1UZJ A;  3N8W B;  1N1I A;  1Q4G A;  2XBV L;  2VVU L;  3LTF B;  2KB9 A;  3LAQ A;  1KSN B;  2MGR A;  1FAX L;  1LPZ A;  1RFN B;  2YGQ A;  5L2Y L;  3ENS A;  1ZAQ A;  3KK6 A;  4D90 A;  4ISH L;  4JZF L;  4BTI A;  1X7A L;  1IOX A;  2H9E L;  1MOX C;  2P28 B;  1B9W A;  1COU A;  2WYJ B;  1PFX L;  1EPH A;  4X8U L;  1F0R B;  1FJS L;  1IP0 A;  1PXX A;  3NTB A;  1WU1 B;  2W26 B;  2DDU A;  1LPG A;  3KQC L;  1DX5 I;  1IGZ A;  3HO4 A;  1EBV A;  3N8X A;  4ZHA B;  2VVC K;  3CS7 L;  4RUT A;  4JYV L;  5JB9 E;  3Q7D A;  2WG3 C;  2P3F L;  2VVV L;  4M11 A;  2YGP A;  2J38 B;  4BTU A;  2K2S B;  4MMZ B;  3SOB B;  3C9A C;  2P93 L;  3Q3K B;  5CKN A;  2XBY L;  3NJP C;  4NA9 L;  3HS7 A;  3N8Y B;  1NQL B;  2VWN L;  2J34 B;  1XFE A;  2J4I B;  3GCX E;  3M36 L;  3OLT A;  4YT7 L;  2EI8 B;  1YO8 A;  5F1A A;  3TBD A;  1A3P A;  2D1J B;  1IVO C;  1PGE A;  2I9A A;  3KCG L;  4Z0L A;  2UWP B;  1U8C B;  2BQ6 A;  3FFG L;  1HZ8 A;  1U67 A;  1WHF A;  1URK A;  5CKQ A;  1DDX A;  1LMJ A;  1NZI A;  3LN1 A;  3BPS E;  1CEJ A;  3TK5 B;  3N8Y A;  2P3F N;  3K9X A;  2P26 A;  3F1S B;  1IJQ A;  5IKR A;  1YUF A;  1MQ6 L;  4Y7A B;  1KLJ L;  1UZQ A;  3HPT A;  1BF9 A;  4Y76 B;  2MGP A;  3QCW A;  3N8V A;  2KNI A;  1IQM L;  2BO2 A;  2G00 L;  4RRW A;  1W8B L;  3LC3 B;  4C16 A;  1HT8 A;  1TOZ A;  3KQE L;  3ASI A;  1IQG L;  4COX A;  4M10 A;  1EMO A;  3IIT B;  5CIS A;  2VWO L;  1FFM A;  1MQ5 L;  2BOX A;  4BXS A;  1J9C L;  2Y7Z B;  3U7U G;  2W3K B;  1M1X B;  2KV4 A;  2OYU P;  1YGC L;  5EGM B;  1HAF A;  3MDL A;  1N7D A;  1Z6C A;  3OLU A;  2P3U A;  1XDT R;  2FLR L;  1FF7 A;  1HAE A;  1GK5 A;  2J2U B;  1YUK B;  3BT1 A;  1HX2 A;  2AYL A;  3HS5 A;  2XC4 L;  2VJ3 A;  2W2O E;  1NFY B;  1HRE A;  1EMN A;  1DVA L;  1YUG A;  2Y80 B;  4NG9 L;  4CSY A;  1NFU B;  4RRY A;  3HO3 A;  3ELA L;  4OTY A;  3CA7 A;  3IJE B;  5L30 L;  2H9E C;  2WG4 B;  1C5M F;  2WPK E;  3N8Z A;  3U73 A;  3R05 A;  2BQ7 A;  4LMF A;  3FCS B;  2BOK L;  2XBW L;  1IQH L;  1EGF A;  1P0S L;  4Y79 B;  3P5B L;  1JBU L;  1FE2 A;  2I9B A;  1ATA A;  1IQN L;  1LQD A;  4RRX A;  5IKV A;  3TK6 B;  4MMX B;  2VWM K;  1EQG A;  2WZP P;  2W2Q E;  1K36 A;  1CX2 A;  3V64 C;  2J94 B;  1ATB A;  1IQK L;  2NPR A;  2RHP A;  1V3X B;  1UZK A;  1G1S A;  1P9J A;  4JZE L;  1PTH A;  3TGF A;  2P3T A;  1KLI L;  4Z6A L;  2YGO A;  4Z0K B;  5JBC E;  1CCV A;  2BOH A;  1CQE A;  4A7I A;  1XKB A;  1HRF A;  2RA0 L;  2M74 A;  2BOU A;  1G2M B;  2W3I B;  3EGF A;  3DEM A;  6COX A;  1EPG A;  1IQI L;  3LIW B;  3M37 L;  5JVZ A;  3S6X A;  4CUF A;  3ZYG A;  1KLO A;  1O5D L;  4Y6D B;  2MHP A;  2WFT A;  1EPJ A;  1LPK A;  1IQL L;  4JYU L;  3CEN L;  1L3Y A;  4YT6 L;  2UWL B;  1LMM A;  5KIR A;  4E1G A;  2FD6 A;  1EAI C;  2J95 B;  4O02 B;  5IKQ A;  2B7D L;  4RS0 A;  3BT2 A;  2F9B L;  4O1Z A;  2WPJ E;  2P94 L;  4MMY B;  3GIS X;  1JL9 A;  3HS6 A;  2FZZ L;  3KRK A;  2XC5 L;  2XC0 L;  1FSB A;  1TLE A;  2PHB B;  1G1Q A;  4Y71 B;  3KQB L;  2FLB L;  2WYG B;  1OB1 C;  5JB8 E;  1UZP A;  1EZQ B;  3SW2 A;  2P95 L;  3HO5 A;  4JZD L;  5F19 A;  5K0H B;  2PR3 B;  5E8D A;  4D0F A;  1ATE A;  4FM5 A;  1APQ A;  3LTG D; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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