1XKBA

Factor xa complexed with a synthetic inhibitor fx-2212a,(2s)-(3'-amidino-3-biphenylyl)-5-(4-pyridylamino)pentanoic acid
Total Genus 17
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
17
sequence length
91
structure length
90
Chain Sequence
DQCETSPCQNQGKCKGLGEYTCTCLEGFEGKNCELFTRKLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTLE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for chemical inhibition of human blood coagulation factor Xa.
pubmed doi rcsb
molecule tags Blood coagulation factor
molecule keywords BLOOD COAGULATION FACTOR XA
total genus 17
structure length 90
sequence length 91
chains with identical sequence B
ec nomenclature ec 3.4.21.6: Coagulation factor Xa.
pdb deposition date 1998-03-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00008 EGF EGF-like domain
A PF14670 FXa_inhibition Coagulation Factor Xa inhibitory site
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 1xkbA02
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 1xkbA01
4C16A 3Q7DA 2BOKL 1G1RA 2EI6B 2OYEP 4ZAEB 1PGEA 1FAKL 1IQHL 4Y7BB 1UZJA 3U73A 1IQML 1HT5A 4BXWA 3C9AC 1JL9A 2WG4B 4ISIL 3POYA 4D0FA 4ZXYL 3SOVA 2I9AA 3HS5A 1NFXB 3LTGD 2W2QE 5JBBE 2F9BL 2JKHL 4CSYA 5F1AA 3ZYIB 1WU1B 1HJ7A 1CCFA 1F7EA 1CQEA 2AYLA 4YT7L 2W2PE 1LPGA 3NJPC 4JZFL 4NA9L 2Y81B 1UZKA 4BTTA 1WHEA 1EPIA 2YGPA 1MQ6L 2P16L 1HT8A 1YUFA 1ATDA 2BQ7A 4Z6AL 1XDTR 1EPJA 2Y5GL 1KLJL 2J95B 2W26B 1P0SL 1DQBA 2VWLL 1K37A 4LMFA 3TK6B 3IJEB 2Y38A 1I0UA 1EMNA 2P3FL 2BQ6A 1ATAA 1IQGL 1M1XB 2FD6A 3KK6A 3N8WA 2YGOA 5JVZA 2GD4A 5L30L 2VWMK 2WPIE 1J9CL 3QH0A 3ZYJB 2UWLB 1XKAL 3NTBA 3QMOA 2VJ3A 5JW1A 2WYGB 2FLBL 2MGPA 1YUGA 5JBAE 1HRFA 2NPRA 4JYVL 1IQEL 2M74A 3ASIA 4TGFA 4BTUA 3OLUA 1JBUL 1DX5I 3LIWB 1EMOA 3RR3A 2Y5FL 3HO5A 5JBCE 3P5BL 1PTHA 1TPGA 3CFWA 1KLIL 2FLGA 2J4IB 3M36L 2KV4A 1YUKB 4RRZA 4Y76B 2P93L 2WPJE 3U7UG 1HAFA 1LMJA 3NT1A 1F0SB 2P3TA 4Y6DB 1B9WA 2B7DL 1CEJA 1FJSL 1W7XL 1IGZA 3CS7L 2XC5L 1O5DL 2H9EL 2PUQL 1ADXA 3NTGA 5JVYA 1G1TA 2XBVL 4MMYB 1Q4GA 2BOXA 1CVWL 2VVCK 2Y5HL 3F1SB 1APQA 1IQFL 1TLEA 4OTYA 2WPLE 4RRWA 2VH0B 4BTIA 3KQEL 1EQHA 1COUA 5I46L 2EI7B 3KQBL 3LTFB 2XBYL 4M10A 3N8VA 2WFXB 1Z6CA 1HCGB 5CKMA 2J38B 4BDXA 2BOUA 1XKBA 1YO8A 1TOZA 1ZAQA 5FDQA 2XBWL 3MQEA 4AQTA 3HPTA 1UZQA 2P28B 3OLTA 1XFEA 4XBMA 5E8DA 1NT0A 5CKNA 1EPGA 1OB1C 4JZEL 1KLOA 1IQNL 1EAIC 3CA7A 2KL7A 2D1JB 1PXXA 1DIYA 2W2OE 4X8VL 1PRHA 2KB9A 3KCGL 1YGCL 1QFKL 1NZIA 2WFTA 1Z6EL 3HS7A 2Y7XB 2WG3C 1FFMA 4Z0KB 2WPME 2W2NE 3N8YB 4FM5A 3TZIA 5EGMB 4D0EA 3ZYGA 3HO3A 3BPSE 2W86A 2BZ6L 5IKRA 3H5CB 1W8BL 1G1QA 2P26A 1FE2A 1LPKA 3FBYA 4CUFA 1C5MF 4BXSA 3M37L 4O1ZA 1EBVA 4RRXA 4BDWA 4Y79B 1DDXA 5COXA 1IOXA 1EGFA 1MQ5L 1CX2A 5IKVA 4JZDL 3KQDL 2FLRL 3V64C 5KN5C 1AUTL 3MDLA 3K9XA 5IKQA 2J2UB 1IQIL 4Z0LA 2VWNL 4JYUL 3HS6A 3KRKA 4M11A 2Q1JB 2CJIB 2PHBB 4X8SL 4XL1A 3N8XA 1IQJL 2XC0L 1P9JA 3GISX 4ZXXL 5KIRA 2PR3B 2K2SB 4PH9A 5IKTA 3LC3B 1EQGA 4O02B 1FAXL 2W3KB 3LN0A 3FCSB 1MOXC 3SW2A 4RUTA 1NFYB 1FF7A 5CISA 2Y7ZB 2W2ME 1IJQA 5K0HB 2I9BA 1KSNB 1NQLB 1IVOC 1IQLL 1G2MB 2RNLA 1EZQB 1N7DA 1NFWB 2OYUP 3V65B 1L3YA 4G1MB 1K36A 4YZUB 1IOEL 1DVAL 1WHFA 1ATBA 4RS0A 3LC5B 3IITB 2BOHA 2P94L 2TGFA 4NGAL 4MMXB 4RRYA 2J94B 1KIGL 3ENSA 3N8YA 3N8ZA 4OTJA 1JV2B 3TK5B 4XLWA 2P95L 1HREA 5F19A 1U8CB 1A3PA 4CUEA 1GK5A 2BMGA 2WPKE 2WPHE 2BQWA 5JB9E 2RHPA 6COXA 2Y80B 3KL6B 1CVUA 3GCXE 1URKA 2Y82B 1NPEB 1G1SA 4D90A 3KQCL 1U67A 2DDUA 3ELAL 2UWPB 1SZBA 3Q3KB 4ISHL 3SOQA 4X8TL 1EPHA 1V3XB 2VVUL 1IQKL 1ATEA 5L2YL 1LPZA 4CUDA 2ADXA 4Y7AB 1F0RB 2UWOB 2VWOL 1LQDA 1HZ8A 2G00L 4COXA 5JB8E 2J34B 3HO4A 3FFGL 1N1IA 4Y71B 1HX2A 1UZPA 2K2TA 3TH3L 2MHPA 1IP0A 2MGRA 4ZH8B 3BT2A 1PFXL 1APOA 3QCWA 4E1GA 3CENL 3LAQA 2VVVL 1L5GB 3TBDA 2XBXL 3R05A 5L2ZL 3BT1A 1NFUB 1FSBA 4ZHAB 1RFNB 3LN1A 3N8WB 4NG9L 4MMZB 1BF9A 3EGFA 1X7AL 2FZZL 2P3FN 2RA0L 1CCVA 2BO2A 3DEMA 5CKQA 1HAEA 2EI8B 4A7IA 3PGHA 3TGFA 1F7MA 1G2LB 2WYJB 2VH6B 2W3IB 3F6UL 4X8UL 4LORA 2XC4L 4YT6L 3SOBB 1IGXA 3GCWE 2P3UA
chains in the Genus database with same CATH superfamily
4C16A 2YGQA 3Q7DA 2BOKL 1G1RA 2EI6B 2OYEP 4ZAEB 1PGEA 1FAKL 1IQHL 4Y7BB 1UZJA 3U73A 1IQML 1HT5A 4BXWA 3C9AC 1JL9A 2WG4B 4ISIL 3POYA 4D0FA 4ZXYL 3SOVA 2I9AA 3HS5A 1NFXB 3LTGD 2W2QE 5JBBE 2F9BL 2JKHL 4CSYA 5F1AA 3ZYIB 1WU1B 1HJ7A 1CCFA 1F7EA 1CQEA 2AYLA 4YT7L 1QIUA 2W2PE 1LPGA 3NJPC 4JZFL 4NA9L 2Y81B 1UZKA 4BTTA 1WHEA 1EPIA 2YGPA 1MQ6L 2P16L 1HT8A 1YUFA 1ATDA 2BQ7A 4Z6AL 1XDTR 1EPJA 2Y5GL 1KLJL 2HORA 2J95B 2BT7A 1P0SL 2W26B 2KNIA 1DQBA 2VWLL 1K37A 4LMFA 3TK6B 3IJEB 2Y38A 1I0UA 1EMNA 2P3FL 2BQ6A 1ATAA 1IQGL 1M1XB 2FD6A 3KK6A 3N8WA 2YGOA 5JVZA 2GD4A 5L30L 2VWMK 2WPIE 2H9EC 1J9CL 3QH0A 3S6XA 3ZYJB 2UWLB 1XKAL 3NTBA 3QMOA 2VJ3A 5JW1A 2WYGB 2FLBL 2MGPA 1YUGA 5JBAE 1HRFA 2NPRA 4JYVL 1IQEL 2M74A 3ASIA 4TGFA 4BTUA 3OLUA 1JBUL 1DX5I 3LIWB 1EMOA 4GU3A 3RR3A 2Y5FL 3HO5A 5JBCE 1LMMA 3P5BL 1PTHA 1TPGA 2BSFA 3CFWA 1KLIL 2FLGA 2J4IB 3M36L 2KV4A 1YUKB 4RRZA 4Y76B 2P93L 2WPJE 3U7UG 1HAFA 1LMJA 3NT1A 1F0SB 2P3TA 4Y6DB 1B9WA 2B7DL 4A94C 1CEJA 1FJSL 1W7XL 1IGZA 3CS7L 2XC5L 1O5DL 2H9EL 2PUQL 2HOXA 1ADXA 3NTGA 5JVYA 1G1TA 2XBVL 4MMYB 1Q4GA 2BOXA 1CVWL 2VVCK 2Y5HL 3F1SB 1APQA 1IQFL 1TLEA 4OTYA 2WPLE 1KKEA 4RRWA 2VH0B 4BTIA 3KQEL 1EQHA 1COUA 5I46L 2EI7B 3KQBL 3LTFB 2XBYL 4M10A 3N8VA 2WFXB 1Z6CA 1HCGB 5CKMA 2J38B 4BDXA 2BOUA 1XKBA 1YO8A 1TOZA 1ZAQA 5FDQA 2XBWL 3MQEA 4AQTA 3HPTA 1UZQA 2P28B 3OLTA 1XFEA 4XBMA 5E8DA 1NT0A 5CKNA 1EPGA 1OB1C 4JZEL 1KLOA 1IQNL 1EAIC 2WZPP 3CA7A 2KL7A 2BT8A 2D1JB 1PXXA 1DIYA 2W2OE 4X8VL 1PRHA 2KB9A 3KCGL 1YGCL 2JJLA 1QFKL 1NZIA 2WFTA 1Z6EL 3HS7A 2Y7XB 2WG3C 1FFMA 4Z0KB 2WPME 2W2NE 3N8YB 4FM5A 3TZIA 5EGMB 4D0EA 3ZYGA 3HO3A 3BPSE 2W86A 2BZ6L 5IKRA 3H5CB 1W8BL 1V1IA 1G1QA 2P26A 1FE2A 1LPKA 3FBYA 4CUFA 1C5MF 4BXSA 3M37L 4O1ZA 1EBVA 4RRXA 4BDWA 4Y79B 1DDXA 5COXA 1IOXA 1EGFA 1MQ5L 2VRSA 1CX2A 5IKVA 4JZDL 3KQDL 2FLRL 3V64C 5KN5C 1AUTL 3MDLA 3K9XA 5IKQA 2J2UB 1IQIL 4Z0LA 2VWNL 4JYUL 3HS6A 3KRKA 4M11A 2Q1JB 2CJIB 2PHBB 4X8SL 4XL1A 3N8XA 1IQJL 2XC0L 1P9JA 3GISX 4ZXXL 5KIRA 1V1HA 2PR3B 2K2SB 4PH9A 5IKTA 3LC3B 1EQGA 4O02B 1FAXL 2W3KB 3LN0A 3FCSB 1MOXC 3SW2A 4RUTA 1NFYB 1FF7A 5CISA 2Y7ZB 2W2ME 1IJQA 5K0HB 2I9BA 1KSNB 1NQLB 1IVOC 1IQLL 1G2MB 2RNLA 1EZQB 1N7DA 1NFWB 2OYUP 3V65B 1L3YA 4G1MB 1K36A 4YZUB 1IOEL 1DVAL 1WHFA 1ATBA 4RS0A 3LC5B 3IITB 2BOHA 2P94L 2TGFA 4NGAL 4MMXB 4RRYA 2J94B 1KIGL 3ENSA 3N8YA 3N8ZA 4OTJA 1JV2B 3TK5B 4XLWA 2P95L 1HREA 5F19A 1U8CB 1A3PA 4CUEA 1GK5A 2BMGA 2WPKE 2WPHE 2BQWA 5JB9E 2RHPA 6COXA 2Y80B 3KL6B 1CVUA 3GCXE 1URKA 2Y82B 1NPEB 1G1SA 4D90A 3KQCL 1U67A 2DDUA 3ELAL 2UWPB 1SZBA 3Q3KB 4ISHL 3SOQA 4X8TL 4GU4A 1EPHA 1V3XB 2VVUL 1IQKL 1ATEA 5L2YL 1LPZA 4CUDA 2ADXA 4Y7AB 1F0RB 2UWOB 2VWOL 1LQDA 1HZ8A 2G00L 4COXA 5JB8E 2J34B 1LK9A 3HO4A 3FFGL 1N1IA 4Y71B 1HX2A 1UZPA 2K2TA 3TH3L 2MHPA 1IP0A 2MGRA 4ZH8B 3BT2A 1PFXL 1APOA 3QCWA 4E1GA 3CENL 3LAQA 2VVVL 1L5GB 3TBDA 2XBXL 3R05A 5L2ZL 3BT1A 1NFUB 1FSBA 4ZHAB 1RFNB 3LN1A 3N8WB 4NG9L 4MMZB 1BF9A 3EGFA 1X7AL 2FZZL 2P3FN 2RA0L 1CCVA 2BO2A 3DEMA 5CKQA 1HAEA 2EI8B 4A7IA 3PGHA 3TGFA 1F7MA 1G2LB 2WYJB 2VH6B 2W3IB 3F6UL 4X8UL 4LORA 2XC4L 4YT6L 3SOBB 1IGXA 3GCWE 2P3UA
chains in the Genus database with same CATH topology
4C16A 2YGQA 3Q7DA 2BOKL 1G1RA 2EI6B 2OYEP 4ZAEB 1PGEA 1FAKL 1IQHL 4Y7BB 1UZJA 3U73A 1IQML 1HT5A 4BXWA 3C9AC 1JL9A 2WG4B 4ISIL 3POYA 4D0FA 4ZXYL 3SOVA 2I9AA 3HS5A 1NFXB 3LTGD 2W2QE 5JBBE 2F9BL 2JKHL 4CSYA 5F1AA 3ZYIB 1WU1B 1HJ7A 1CCFA 1F7EA 1CQEA 2AYLA 4YT7L 2W2PE 1LPGA 3NJPC 4JZFL 4NA9L 2Y81B 1UZKA 4BTTA 1WHEA 1EPIA 2YGPA 1MQ6L 2P16L 1HT8A 1YUFA 1ATDA 2BQ7A 4Z6AL 1XDTR 1EPJA 2Y5GL 1KLJL 2J95B 2W26B 1P0SL 2KNIA 1DQBA 2VWLL 1K37A 4LMFA 3TK6B 3IJEB 2Y38A 1I0UA 1EMNA 2P3FL 2BQ6A 1ATAA 1IQGL 1M1XB 2FD6A 3KK6A 3N8WA 2YGOA 5JVZA 2GD4A 5L30L 2VWMK 2WPIE 2H9EC 1J9CL 3QH0A 3S6XA 3ZYJB 2UWLB 1XKAL 3NTBA 3QMOA 2VJ3A 5JW1A 2WYGB 2FLBL 2MGPA 1YUGA 5JBAE 1HRFA 2NPRA 4JYVL 1IQEL 2M74A 3ASIA 4TGFA 4BTUA 3OLUA 1JBUL 1DX5I 3LIWB 1EMOA 3RR3A 2Y5FL 3HO5A 5JBCE 1LMMA 3P5BL 1PTHA 1TPGA 3CFWA 1KLIL 2FLGA 2J4IB 3M36L 2KV4A 1YUKB 4RRZA 4Y76B 2P93L 2WPJE 3U7UG 1HAFA 1LMJA 3NT1A 1F0SB 2P3TA 4Y6DB 1B9WA 2B7DL 4A94C 1CEJA 1FJSL 1W7XL 1IGZA 3CS7L 2XC5L 1O5DL 2H9EL 2PUQL 1ADXA 3NTGA 5JVYA 1G1TA 2XBVL 4MMYB 1Q4GA 2BOXA 1CVWL 2VVCK 2Y5HL 3F1SB 1APQA 1IQFL 1TLEA 4OTYA 2WPLE 4RRWA 2VH0B 4BTIA 3KQEL 1EQHA 1COUA 5I46L 2EI7B 3KQBL 3LTFB 2XBYL 4M10A 3N8VA 2WFXB 1Z6CA 1HCGB 5CKMA 2J38B 4BDXA 2BOUA 1XKBA 1YO8A 1TOZA 1ZAQA 5FDQA 2XBWL 3MQEA 4AQTA 3HPTA 1UZQA 2P28B 3OLTA 1XFEA 4XBMA 5E8DA 1NT0A 5CKNA 1EPGA 1OB1C 4JZEL 1KLOA 1IQNL 1EAIC 2WZPP 3CA7A 2KL7A 2D1JB 1PXXA 1DIYA 2W2OE 4X8VL 1PRHA 2KB9A 3KCGL 1YGCL 1QFKL 1NZIA 2WFTA 1Z6EL 3HS7A 2Y7XB 2WG3C 1FFMA 4Z0KB 2WPME 2W2NE 3N8YB 4FM5A 3TZIA 5EGMB 4D0EA 3ZYGA 3HO3A 3BPSE 2W86A 2BZ6L 5IKRA 3H5CB 1W8BL 1G1QA 2P26A 1FE2A 1LPKA 3FBYA 4CUFA 1C5MF 4BXSA 3M37L 4O1ZA 1EBVA 4RRXA 4BDWA 4Y79B 1DDXA 5COXA 1IOXA 1EGFA 1MQ5L 1CX2A 5IKVA 4JZDL 3KQDL 2FLRL 3V64C 5KN5C 1AUTL 3MDLA 3K9XA 5IKQA 2J2UB 1IQIL 4Z0LA 2VWNL 4JYUL 3HS6A 3KRKA 4M11A 2Q1JB 2CJIB 2PHBB 4X8SL 4XL1A 3N8XA 1IQJL 2XC0L 1P9JA 3GISX 4ZXXL 5KIRA 2PR3B 2K2SB 4PH9A 5IKTA 3LC3B 1EQGA 4O02B 1FAXL 2W3KB 3LN0A 3FCSB 1MOXC 3SW2A 4RUTA 1NFYB 1FF7A 5CISA 2Y7ZB 2W2ME 1IJQA 5K0HB 2I9BA 1KSNB 1NQLB 1IVOC 1IQLL 1G2MB 2RNLA 1EZQB 1N7DA 1NFWB 2OYUP 3V65B 1L3YA 4G1MB 1K36A 4YZUB 1IOEL 1DVAL 1WHFA 1ATBA 4RS0A 3LC5B 3IITB 2BOHA 2P94L 2TGFA 4NGAL 4MMXB 4RRYA 2J94B 1KIGL 3ENSA 3N8YA 3N8ZA 4OTJA 1JV2B 3TK5B 4XLWA 2P95L 1HREA 5F19A 1U8CB 1A3PA 4CUEA 1GK5A 2BMGA 2WPKE 2WPHE 2BQWA 5JB9E 2RHPA 6COXA 2Y80B 3KL6B 1CVUA 3GCXE 1URKA 2Y82B 1NPEB 1G1SA 4D90A 3KQCL 1U67A 2DDUA 3ELAL 2UWPB 1SZBA 3Q3KB 4ISHL 3SOQA 4X8TL 1EPHA 1V3XB 2VVUL 1IQKL 1ATEA 5L2YL 1LPZA 4CUDA 2ADXA 4Y7AB 1F0RB 2UWOB 2VWOL 1LQDA 1HZ8A 2G00L 4COXA 5JB8E 2J34B 3HO4A 3FFGL 1N1IA 4Y71B 1HX2A 1UZPA 2K2TA 3TH3L 2MHPA 1IP0A 2MGRA 4ZH8B 3BT2A 1PFXL 1APOA 3QCWA 4E1GA 3CENL 3LAQA 2VVVL 1L5GB 3TBDA 2XBXL 3R05A 5L2ZL 3BT1A 1NFUB 1FSBA 4ZHAB 1RFNB 3LN1A 3N8WB 4NG9L 4MMZB 1BF9A 3EGFA 1X7AL 2FZZL 2P3FN 2RA0L 1CCVA 2BO2A 3DEMA 5CKQA 1HAEA 2EI8B 4A7IA 3PGHA 3TGFA 1F7MA 1G2LB 2WYJB 2VH6B 2W3IB 3F6UL 4X8UL 4LORA 2XC4L 4YT6L 3SOBB 1IGXA 3GCWE 2P3UA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4C16 A;  3Q7D A;  2BOK L;  1G1R A;  2EI6 B;  2OYE P;  4ZAE B;  1PGE A;  1FAK L;  1IQH L;  4Y7B B;  1UZJ A;  3U73 A;  1IQM L;  1HT5 A;  4BXW A;  3C9A C;  1JL9 A;  2WG4 B;  4ISI L;  3POY A;  4D0F A;  4ZXY L;  3SOV A;  2I9A A;  3HS5 A;  1NFX B;  3LTG D;  2W2Q E;  5JBB E;  2F9B L;  2JKH L;  4CSY A;  5F1A A;  3ZYI B;  1WU1 B;  1HJ7 A;  1CCF A;  1F7E A;  1CQE A;  2AYL A;  4YT7 L;  2W2P E;  1LPG A;  3NJP C;  4JZF L;  4NA9 L;  2Y81 B;  1UZK A;  4BTT A;  1WHE A;  1EPI A;  2YGP A;  1MQ6 L;  2P16 L;  1HT8 A;  1YUF A;  1ATD A;  2BQ7 A;  4Z6A L;  1XDT R;  1EPJ A;  2Y5G L;  1KLJ L;  2J95 B;  2W26 B;  1P0S L;  1DQB A;  2VWL L;  1K37 A;  4LMF A;  3TK6 B;  3IJE B;  2Y38 A;  1I0U A;  1EMN A;  2P3F L;  2BQ6 A;  1ATA A;  1IQG L;  1M1X B;  2FD6 A;  3KK6 A;  3N8W A;  2YGO A;  5JVZ A;  2GD4 A;  5L30 L;  2VWM K;  2WPI E;  1J9C L;  3QH0 A;  3ZYJ B;  2UWL B;  1XKA L;  3NTB A;  3QMO A;  2VJ3 A;  5JW1 A;  2WYG B;  2FLB L;  2MGP A;  1YUG A;  5JBA E;  1HRF A;  2NPR A;  4JYV L;  1IQE L;  2M74 A;  3ASI A;  4TGF A;  4BTU A;  3OLU A;  1JBU L;  1DX5 I;  3LIW B;  1EMO A;  3RR3 A;  2Y5F L;  3HO5 A;  5JBC E;  3P5B L;  1PTH A;  1TPG A;  3CFW A;  1KLI L;  2FLG A;  2J4I B;  3M36 L;  2KV4 A;  1YUK B;  4RRZ A;  4Y76 B;  2P93 L;  2WPJ E;  3U7U G;  1HAF A;  1LMJ A;  3NT1 A;  1F0S B;  2P3T A;  4Y6D B;  1B9W A;  2B7D L;  1CEJ A;  1FJS L;  1W7X L;  1IGZ A;  3CS7 L;  2XC5 L;  1O5D L;  2H9E L;  2PUQ L;  1ADX A;  3NTG A;  5JVY A;  1G1T A;  2XBV L;  4MMY B;  1Q4G A;  2BOX A;  1CVW L;  2VVC K;  2Y5H L;  3F1S B;  1APQ A;  1IQF L;  1TLE A;  4OTY A;  2WPL E;  4RRW A;  2VH0 B;  4BTI A;  3KQE L;  1EQH A;  1COU A;  5I46 L;  2EI7 B;  3KQB L;  3LTF B;  2XBY L;  4M10 A;  3N8V A;  2WFX B;  1Z6C A;  1HCG B;  5CKM A;  2J38 B;  4BDX A;  2BOU A;  1XKB A;  1YO8 A;  1TOZ A;  1ZAQ A;  5FDQ A;  2XBW L;  3MQE A;  4AQT A;  3HPT A;  1UZQ A;  2P28 B;  3OLT A;  1XFE A;  4XBM A;  5E8D A;  1NT0 A;  5CKN A;  1EPG A;  1OB1 C;  4JZE L;  1KLO A;  1IQN L;  1EAI C;  3CA7 A;  2KL7 A;  2D1J B;  1PXX A;  1DIY A;  2W2O E;  4X8V L;  1PRH A;  2KB9 A;  3KCG L;  1YGC L;  1QFK L;  1NZI A;  2WFT A;  1Z6E L;  3HS7 A;  2Y7X B;  2WG3 C;  1FFM A;  4Z0K B;  2WPM E;  2W2N E;  3N8Y B;  4FM5 A;  3TZI A;  5EGM B;  4D0E A;  3ZYG A;  3HO3 A;  3BPS E;  2W86 A;  2BZ6 L;  5IKR A;  3H5C B;  1W8B L;  1G1Q A;  2P26 A;  1FE2 A;  1LPK A;  3FBY A;  4CUF A;  1C5M F;  4BXS A;  3M37 L;  4O1Z A;  1EBV A;  4RRX A;  4BDW A;  4Y79 B;  1DDX A;  5COX A;  1IOX A;  1EGF A;  1MQ5 L;  1CX2 A;  5IKV A;  4JZD L;  3KQD L;  2FLR L;  3V64 C;  5KN5 C;  1AUT L;  3MDL A;  3K9X A;  5IKQ A;  2J2U B;  1IQI L;  4Z0L A;  2VWN L;  4JYU L;  3HS6 A;  3KRK A;  4M11 A;  2Q1J B;  2CJI B;  2PHB B;  4X8S L;  4XL1 A;  3N8X A;  1IQJ L;  2XC0 L;  1P9J A;  3GIS X;  4ZXX L;  5KIR A;  2PR3 B;  2K2S B;  4PH9 A;  5IKT A;  3LC3 B;  1EQG A;  4O02 B;  1FAX L;  2W3K B;  3LN0 A;  3FCS B;  1MOX C;  3SW2 A;  4RUT A;  1NFY B;  1FF7 A;  5CIS A;  2Y7Z B;  2W2M E;  1IJQ A;  5K0H B;  2I9B A;  1KSN B;  1NQL B;  1IVO C;  1IQL L;  1G2M B;  2RNL A;  1EZQ B;  1N7D A;  1NFW B;  2OYU P;  3V65 B;  1L3Y A;  4G1M B;  1K36 A;  4YZU B;  1IOE L;  1DVA L;  1WHF A;  1ATB A;  4RS0 A;  3LC5 B;  3IIT B;  2BOH A;  2P94 L;  2TGF A;  4NGA L;  4MMX B;  4RRY A;  2J94 B;  1KIG L;  3ENS A;  3N8Y A;  3N8Z A;  4OTJ A;  1JV2 B;  3TK5 B;  4XLW A;  2P95 L;  1HRE A;  5F19 A;  1U8C B;  1A3P A;  4CUE A;  1GK5 A;  2BMG A;  2WPK E;  2WPH E;  2BQW A;  5JB9 E;  2RHP A;  6COX A;  2Y80 B;  3KL6 B;  1CVU A;  3GCX E;  1URK A;  2Y82 B;  1NPE B;  1G1S A;  4D90 A;  3KQC L;  1U67 A;  2DDU A;  3ELA L;  2UWP B;  1SZB A;  3Q3K B;  4ISH L;  3SOQ A;  4X8T L;  1EPH A;  1V3X B;  2VVU L;  1IQK L;  1ATE A;  5L2Y L;  1LPZ A;  4CUD A;  2ADX A;  4Y7A B;  1F0R B;  2UWO B;  2VWO L;  1LQD A;  1HZ8 A;  2G00 L;  4COX A;  5JB8 E;  2J34 B;  3HO4 A;  3FFG L;  1N1I A;  4Y71 B;  1HX2 A;  1UZP A;  2K2T A;  3TH3 L;  2MHP A;  1IP0 A;  2MGR A;  4ZH8 B;  3BT2 A;  1PFX L;  1APO A;  3QCW A;  4E1G A;  3CEN L;  3LAQ A;  2VVV L;  1L5G B;  3TBD A;  2XBX L;  3R05 A;  5L2Z L;  3BT1 A;  1NFU B;  1FSB A;  4ZHA B;  1RFN B;  3LN1 A;  3N8W B;  4NG9 L;  4MMZ B;  1BF9 A;  3EGF A;  1X7A L;  2FZZ L;  2P3F N;  2RA0 L;  1CCV A;  2BO2 A;  3DEM A;  5CKQ A;  1HAE A;  2EI8 B;  4A7I A;  3PGH A;  3TGF A;  1F7M A;  1G2L B;  2WYJ B;  2VH6 B;  2W3I B;  3F6U L;  4X8U L;  4LOR A;  2XC4 L;  4YT6 L;  3SOB B;  1IGX A;  3GCW E;  2P3U A; 
#chains in the Genus database with same CATH topology
 4C16 A;  2YGQ A;  3Q7D A;  2BOK L;  1G1R A;  2EI6 B;  2OYE P;  4ZAE B;  1PGE A;  1FAK L;  1IQH L;  4Y7B B;  1UZJ A;  3U73 A;  1IQM L;  1HT5 A;  4BXW A;  3C9A C;  1JL9 A;  2WG4 B;  4ISI L;  3POY A;  4D0F A;  4ZXY L;  3SOV A;  2I9A A;  3HS5 A;  1NFX B;  3LTG D;  2W2Q E;  5JBB E;  2F9B L;  2JKH L;  4CSY A;  5F1A A;  3ZYI B;  1WU1 B;  1HJ7 A;  1CCF A;  1F7E A;  1CQE A;  2AYL A;  4YT7 L;  1QIU A;  2W2P E;  1LPG A;  3NJP C;  4JZF L;  4NA9 L;  2Y81 B;  1UZK A;  4BTT A;  1WHE A;  1EPI A;  2YGP A;  1MQ6 L;  2P16 L;  1HT8 A;  1YUF A;  1ATD A;  2BQ7 A;  4Z6A L;  1XDT R;  1EPJ A;  2Y5G L;  1KLJ L;  2HOR A;  2J95 B;  2BT7 A;  1P0S L;  2W26 B;  2KNI A;  1DQB A;  2VWL L;  1K37 A;  4LMF A;  3TK6 B;  3IJE B;  2Y38 A;  1I0U A;  1EMN A;  2P3F L;  2BQ6 A;  1ATA A;  1IQG L;  1M1X B;  2FD6 A;  3KK6 A;  3N8W A;  2YGO A;  5JVZ A;  2GD4 A;  5L30 L;  2VWM K;  2WPI E;  2H9E C;  1J9C L;  3QH0 A;  3S6X A;  3ZYJ B;  2UWL B;  1XKA L;  3NTB A;  3QMO A;  2VJ3 A;  5JW1 A;  2WYG B;  2FLB L;  2MGP A;  1YUG A;  5JBA E;  1HRF A;  2NPR A;  4JYV L;  1IQE L;  2M74 A;  3ASI A;  4TGF A;  4BTU A;  3OLU A;  1JBU L;  1DX5 I;  3LIW B;  1EMO A;  4GU3 A;  3RR3 A;  2Y5F L;  3HO5 A;  5JBC E;  1LMM A;  3P5B L;  1PTH A;  1TPG A;  2BSF A;  3CFW A;  1KLI L;  2FLG A;  2J4I B;  3M36 L;  2KV4 A;  1YUK B;  4RRZ A;  4Y76 B;  2P93 L;  2WPJ E;  3U7U G;  1HAF A;  1LMJ A;  3NT1 A;  1F0S B;  2P3T A;  4Y6D B;  1B9W A;  2B7D L;  4A94 C;  1CEJ A;  1FJS L;  1W7X L;  1IGZ A;  3CS7 L;  2XC5 L;  1O5D L;  2H9E L;  2PUQ L;  2HOX A;  1ADX A;  3NTG A;  5JVY A;  1G1T A;  2XBV L;  4MMY B;  1Q4G A;  2BOX A;  1CVW L;  2VVC K;  2Y5H L;  3F1S B;  1APQ A;  1IQF L;  1TLE A;  4OTY A;  2WPL E;  1KKE A;  4RRW A;  2VH0 B;  4BTI A;  3KQE L;  1EQH A;  1COU A;  5I46 L;  2EI7 B;  3KQB L;  3LTF B;  2XBY L;  4M10 A;  3N8V A;  2WFX B;  1Z6C A;  1HCG B;  5CKM A;  2J38 B;  4BDX A;  2BOU A;  1XKB A;  1YO8 A;  1TOZ A;  1ZAQ A;  5FDQ A;  2XBW L;  3MQE A;  4AQT A;  3HPT A;  1UZQ A;  2P28 B;  3OLT A;  1XFE A;  4XBM A;  5E8D A;  1NT0 A;  5CKN A;  1EPG A;  1OB1 C;  4JZE L;  1KLO A;  1IQN L;  1EAI C;  2WZP P;  3CA7 A;  2KL7 A;  2BT8 A;  2D1J B;  1PXX A;  1DIY A;  2W2O E;  4X8V L;  1PRH A;  2KB9 A;  3KCG L;  1YGC L;  2JJL A;  1QFK L;  1NZI A;  2WFT A;  1Z6E L;  3HS7 A;  2Y7X B;  2WG3 C;  1FFM A;  4Z0K B;  2WPM E;  2W2N E;  3N8Y B;  4FM5 A;  3TZI A;  5EGM B;  4D0E A;  3ZYG A;  3HO3 A;  3BPS E;  2W86 A;  2BZ6 L;  5IKR A;  3H5C B;  1W8B L;  1V1I A;  1G1Q A;  2P26 A;  1FE2 A;  1LPK A;  3FBY A;  4CUF A;  1C5M F;  4BXS A;  3M37 L;  4O1Z A;  1EBV A;  4RRX A;  4BDW A;  4Y79 B;  1DDX A;  5COX A;  1IOX A;  1EGF A;  1MQ5 L;  2VRS A;  1CX2 A;  5IKV A;  4JZD L;  3KQD L;  2FLR L;  3V64 C;  5KN5 C;  1AUT L;  3MDL A;  3K9X A;  5IKQ A;  2J2U B;  1IQI L;  4Z0L A;  2VWN L;  4JYU L;  3HS6 A;  3KRK A;  4M11 A;  2Q1J B;  2CJI B;  2PHB B;  4X8S L;  4XL1 A;  3N8X A;  1IQJ L;  2XC0 L;  1P9J A;  3GIS X;  4ZXX L;  5KIR A;  1V1H A;  2PR3 B;  2K2S B;  4PH9 A;  5IKT A;  3LC3 B;  1EQG A;  4O02 B;  1FAX L;  2W3K B;  3LN0 A;  3FCS B;  1MOX C;  3SW2 A;  4RUT A;  1NFY B;  1FF7 A;  5CIS A;  2Y7Z B;  2W2M E;  1IJQ A;  5K0H B;  2I9B A;  1KSN B;  1NQL B;  1IVO C;  1IQL L;  1G2M B;  2RNL A;  1EZQ B;  1N7D A;  1NFW B;  2OYU P;  3V65 B;  1L3Y A;  4G1M B;  1K36 A;  4YZU B;  1IOE L;  1DVA L;  1WHF A;  1ATB A;  4RS0 A;  3LC5 B;  3IIT B;  2BOH A;  2P94 L;  2TGF A;  4NGA L;  4MMX B;  4RRY A;  2J94 B;  1KIG L;  3ENS A;  3N8Y A;  3N8Z A;  4OTJ A;  1JV2 B;  3TK5 B;  4XLW A;  2P95 L;  1HRE A;  5F19 A;  1U8C B;  1A3P A;  4CUE A;  1GK5 A;  2BMG A;  2WPK E;  2WPH E;  2BQW A;  5JB9 E;  2RHP A;  6COX A;  2Y80 B;  3KL6 B;  1CVU A;  3GCX E;  1URK A;  2Y82 B;  1NPE B;  1G1S A;  4D90 A;  3KQC L;  1U67 A;  2DDU A;  3ELA L;  2UWP B;  1SZB A;  3Q3K B;  4ISH L;  3SOQ A;  4X8T L;  4GU4 A;  1EPH A;  1V3X B;  2VVU L;  1IQK L;  1ATE A;  5L2Y L;  1LPZ A;  4CUD A;  2ADX A;  4Y7A B;  1F0R B;  2UWO B;  2VWO L;  1LQD A;  1HZ8 A;  2G00 L;  4COX A;  5JB8 E;  2J34 B;  1LK9 A;  3HO4 A;  3FFG L;  1N1I A;  4Y71 B;  1HX2 A;  1UZP A;  2K2T A;  3TH3 L;  2MHP A;  1IP0 A;  2MGR A;  4ZH8 B;  3BT2 A;  1PFX L;  1APO A;  3QCW A;  4E1G A;  3CEN L;  3LAQ A;  2VVV L;  1L5G B;  3TBD A;  2XBX L;  3R05 A;  5L2Z L;  3BT1 A;  1NFU B;  1FSB A;  4ZHA B;  1RFN B;  3LN1 A;  3N8W B;  4NG9 L;  4MMZ B;  1BF9 A;  3EGF A;  1X7A L;  2FZZ L;  2P3F N;  2RA0 L;  1CCV A;  2BO2 A;  3DEM A;  5CKQ A;  1HAE A;  2EI8 B;  4A7I A;  3PGH A;  3TGF A;  1F7M A;  1G2L B;  2WYJ B;  2VH6 B;  2W3I B;  3F6U L;  4X8U L;  4LOR A;  2XC4 L;  4YT6 L;  3SOB B;  1IGX A;  3GCW E;  2P3U A; 
#chains in the Genus database with same CATH homology
 4C16 A;  2YGQ A;  3Q7D A;  2BOK L;  1G1R A;  2EI6 B;  2OYE P;  4ZAE B;  1PGE A;  1FAK L;  1IQH L;  4Y7B B;  1UZJ A;  3U73 A;  1IQM L;  1HT5 A;  4BXW A;  3C9A C;  1JL9 A;  2WG4 B;  4ISI L;  3POY A;  4D0F A;  4ZXY L;  3SOV A;  2I9A A;  3HS5 A;  1NFX B;  3LTG D;  2W2Q E;  5JBB E;  2F9B L;  2JKH L;  4CSY A;  5F1A A;  3ZYI B;  1WU1 B;  1HJ7 A;  1CCF A;  1F7E A;  1CQE A;  2AYL A;  4YT7 L;  2W2P E;  1LPG A;  3NJP C;  4JZF L;  4NA9 L;  2Y81 B;  1UZK A;  4BTT A;  1WHE A;  1EPI A;  2YGP A;  1MQ6 L;  2P16 L;  1HT8 A;  1YUF A;  1ATD A;  2BQ7 A;  4Z6A L;  1XDT R;  1EPJ A;  2Y5G L;  1KLJ L;  2J95 B;  2W26 B;  1P0S L;  2KNI A;  1DQB A;  2VWL L;  1K37 A;  4LMF A;  3TK6 B;  3IJE B;  2Y38 A;  1I0U A;  1EMN A;  2P3F L;  2BQ6 A;  1ATA A;  1IQG L;  1M1X B;  2FD6 A;  3KK6 A;  3N8W A;  2YGO A;  5JVZ A;  2GD4 A;  5L30 L;  2VWM K;  2WPI E;  2H9E C;  1J9C L;  3QH0 A;  3S6X A;  3ZYJ B;  2UWL B;  1XKA L;  3NTB A;  3QMO A;  2VJ3 A;  5JW1 A;  2WYG B;  2FLB L;  2MGP A;  1YUG A;  5JBA E;  1HRF A;  2NPR A;  4JYV L;  1IQE L;  2M74 A;  3ASI A;  4TGF A;  4BTU A;  3OLU A;  1JBU L;  1DX5 I;  3LIW B;  1EMO A;  3RR3 A;  2Y5F L;  3HO5 A;  5JBC E;  1LMM A;  3P5B L;  1PTH A;  1TPG A;  3CFW A;  1KLI L;  2FLG A;  2J4I B;  3M36 L;  2KV4 A;  1YUK B;  4RRZ A;  4Y76 B;  2P93 L;  2WPJ E;  3U7U G;  1HAF A;  1LMJ A;  3NT1 A;  1F0S B;  2P3T A;  4Y6D B;  1B9W A;  2B7D L;  4A94 C;  1CEJ A;  1FJS L;  1W7X L;  1IGZ A;  3CS7 L;  2XC5 L;  1O5D L;  2H9E L;  2PUQ L;  1ADX A;  3NTG A;  5JVY A;  1G1T A;  2XBV L;  4MMY B;  1Q4G A;  2BOX A;  1CVW L;  2VVC K;  2Y5H L;  3F1S B;  1APQ A;  1IQF L;  1TLE A;  4OTY A;  2WPL E;  4RRW A;  2VH0 B;  4BTI A;  3KQE L;  1EQH A;  1COU A;  5I46 L;  2EI7 B;  3KQB L;  3LTF B;  2XBY L;  4M10 A;  3N8V A;  2WFX B;  1Z6C A;  1HCG B;  5CKM A;  2J38 B;  4BDX A;  2BOU A;  1XKB A;  1YO8 A;  1TOZ A;  1ZAQ A;  5FDQ A;  2XBW L;  3MQE A;  4AQT A;  3HPT A;  1UZQ A;  2P28 B;  3OLT A;  1XFE A;  4XBM A;  5E8D A;  1NT0 A;  5CKN A;  1EPG A;  1OB1 C;  4JZE L;  1KLO A;  1IQN L;  1EAI C;  2WZP P;  3CA7 A;  2KL7 A;  2D1J B;  1PXX A;  1DIY A;  2W2O E;  4X8V L;  1PRH A;  2KB9 A;  3KCG L;  1YGC L;  1QFK L;  1NZI A;  2WFT A;  1Z6E L;  3HS7 A;  2Y7X B;  2WG3 C;  1FFM A;  4Z0K B;  2WPM E;  2W2N E;  3N8Y B;  4FM5 A;  3TZI A;  5EGM B;  4D0E A;  3ZYG A;  3HO3 A;  3BPS E;  2W86 A;  2BZ6 L;  5IKR A;  3H5C B;  1W8B L;  1G1Q A;  2P26 A;  1FE2 A;  1LPK A;  3FBY A;  4CUF A;  1C5M F;  4BXS A;  3M37 L;  4O1Z A;  1EBV A;  4RRX A;  4BDW A;  4Y79 B;  1DDX A;  5COX A;  1IOX A;  1EGF A;  1MQ5 L;  1CX2 A;  5IKV A;  4JZD L;  3KQD L;  2FLR L;  3V64 C;  5KN5 C;  1AUT L;  3MDL A;  3K9X A;  5IKQ A;  2J2U B;  1IQI L;  4Z0L A;  2VWN L;  4JYU L;  3HS6 A;  3KRK A;  4M11 A;  2Q1J B;  2CJI B;  2PHB B;  4X8S L;  4XL1 A;  3N8X A;  1IQJ L;  2XC0 L;  1P9J A;  3GIS X;  4ZXX L;  5KIR A;  2PR3 B;  2K2S B;  4PH9 A;  5IKT A;  3LC3 B;  1EQG A;  4O02 B;  1FAX L;  2W3K B;  3LN0 A;  3FCS B;  1MOX C;  3SW2 A;  4RUT A;  1NFY B;  1FF7 A;  5CIS A;  2Y7Z B;  2W2M E;  1IJQ A;  5K0H B;  2I9B A;  1KSN B;  1NQL B;  1IVO C;  1IQL L;  1G2M B;  2RNL A;  1EZQ B;  1N7D A;  1NFW B;  2OYU P;  3V65 B;  1L3Y A;  4G1M B;  1K36 A;  4YZU B;  1IOE L;  1DVA L;  1WHF A;  1ATB A;  4RS0 A;  3LC5 B;  3IIT B;  2BOH A;  2P94 L;  2TGF A;  4NGA L;  4MMX B;  4RRY A;  2J94 B;  1KIG L;  3ENS A;  3N8Y A;  3N8Z A;  4OTJ A;  1JV2 B;  3TK5 B;  4XLW A;  2P95 L;  1HRE A;  5F19 A;  1U8C B;  1A3P A;  4CUE A;  1GK5 A;  2BMG A;  2WPK E;  2WPH E;  2BQW A;  5JB9 E;  2RHP A;  6COX A;  2Y80 B;  3KL6 B;  1CVU A;  3GCX E;  1URK A;  2Y82 B;  1NPE B;  1G1S A;  4D90 A;  3KQC L;  1U67 A;  2DDU A;  3ELA L;  2UWP B;  1SZB A;  3Q3K B;  4ISH L;  3SOQ A;  4X8T L;  1EPH A;  1V3X B;  2VVU L;  1IQK L;  1ATE A;  5L2Y L;  1LPZ A;  4CUD A;  2ADX A;  4Y7A B;  1F0R B;  2UWO B;  2VWO L;  1LQD A;  1HZ8 A;  2G00 L;  4COX A;  5JB8 E;  2J34 B;  3HO4 A;  3FFG L;  1N1I A;  4Y71 B;  1HX2 A;  1UZP A;  2K2T A;  3TH3 L;  2MHP A;  1IP0 A;  2MGR A;  4ZH8 B;  3BT2 A;  1PFX L;  1APO A;  3QCW A;  4E1G A;  3CEN L;  3LAQ A;  2VVV L;  1L5G B;  3TBD A;  2XBX L;  3R05 A;  5L2Z L;  3BT1 A;  1NFU B;  1FSB A;  4ZHA B;  1RFN B;  3LN1 A;  3N8W B;  4NG9 L;  4MMZ B;  1BF9 A;  3EGF A;  1X7A L;  2FZZ L;  2P3F N;  2RA0 L;  1CCV A;  2BO2 A;  3DEM A;  5CKQ A;  1HAE A;  2EI8 B;  4A7I A;  3PGH A;  3TGF A;  1F7M A;  1G2L B;  2WYJ B;  2VH6 B;  2W3I B;  3F6U L;  4X8U L;  4LOR A;  2XC4 L;  4YT6 L;  3SOB B;  1IGX A;  3GCW E;  2P3U A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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