4BTIA

Factor xa in complex with the dual thrombin-fxa inhibitor 58.
Total Genus 10
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
10
sequence length
53
structure length
53
Chain Sequence
RKLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTLE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title 5-Chlorothiophene-2-Carboxylic Acid [(S)-2-[2-Methyl-3-(2-Oxopyrrolidin-1-Yl)Benzenesulfonylamino]-3-(4-Methylpiperazin-1-Yl)-3-Oxopropyl]Amide (Sar107375), a Selective and Potent Orally Active Dual Thrombin and Factor Xa Inhibitor.
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords COAGULATION FACTOR X HEAVY CHAIN
total genus 10
structure length 53
sequence length 53
chains with identical sequence E
ec nomenclature ec 3.4.21.6: Coagulation factor Xa.
pdb deposition date 2013-06-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00008 EGF EGF-like domain
A PF14670 FXa_inhibition Coagulation Factor Xa inhibitory site
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 4btiA00
3TK5B 2WFXB 2BOKL 4Z0KB 2J94B 3P5BL 3QCWA 2FZZL 3K9XA 5FDQA 3GCXE 1N7DA 3KQDL 3LTFB 3V64C 1HRFA 1HCGB 3ENSA 1PTHA 1Z6EL 1X7AL 1PGEA 2YGPA 3F6UL 4LMFA 4RRWA 4YZUB 4XL1A 2FLGA 3QH0A 5JBAE 3TGFA 1EQHA 4Y79B 4PH9A 1IQIL 2EI7B 4CSYA 5EGMB 1JL9A 3U7UG 1PFXL 3TBDA 2BQWA 1KLJL 1PXXA 3R05A 3KCGL 4X8VL 1CCFA 3CA7A 3HPTA 2P93L 2MGRA 3SOVA 3MQEA 1IVOC 4Y6DB 1ADXA 3N8WB 2XBWL 3HO3A 2KL7A 1EMNA 4XBMA 2P3UA 3KRKA 4ZHAB 5IKTA 1DVAL 3TK6B 1NT0A 5IKQA 1CQEA 1LPZA 1UZKA 1K36A 2Y38A 3F1SB 5CKNA 2WPHE 4MMXB 2WPKE 1IQHL 3EGFA 1P0SL 5K0HB 2J38B 1MQ6L 2VJ3A 3N8YB 3Q3KB 1B9WA 4ZXXL 2K2SB 2P3TA 2W2ME 1HAFA 1ATAA 3MDLA 3LIWB 4ZAEB 4RRYA 3DEMA 2VWNL 1LQDA 2WPME 2WFTA 1UZPA 2DDUA 2BOXA 4ZH8B 2MGPA 2VWMK 1K37A 2XC5L 3CS7L 1XFEA 3C9AC 2CJIB 3RR3A 1N1IA 2W2QE 2XBXL 1EAIC 3BT1A 1FE2A 4ISHL 2J2UB 1CX2A 2F9BL 4YT6L 3SW2A 4LORA 4FM5A 5I46L 1XKBA 4BTUA 1CEJA 1FSBA 2Y7XB 1Z6CA 5L2ZL 1FAXL 2P16L 4RS0A 1G1SA 3KL6B 2WYGB 4MMZB 2J34B 1LPGA 1FJSL 2Y81B 2BO2A 2W2PE 2YGOA 1O5DL 3LC3B 3LN1A 3M36L 2NPRA 2Y5GL 1COUA 2BMGA 3LC5B 2XBYL 2BOUA 3FBYA 2WPIE 1YO8A 1EGFA 2BOHA 5CISA 1DQBA 1MQ5L 1C5MF 4X8TL 1WU1B 2VH0B 1URKA 3SOQA 3ASIA 4E1GA 4Y76B 1IGXA 1OB1C 4X8SL 2W2OE 3LTGD 1EPIA 2PR3B 1HJ7A 2P3FL 1I0UA 1HREA 3OLUA 3V65B 1IQKL 4BXSA 4M11A 1KLIL 1G1RA 1HZ8A 1XDTR 2WG3C 1F7EA 2H9EL 3HO4A 1F0SB 3ELAL 4X8UL 2GD4A 1G2MB 4OTYA 3N8VA 2P26A 1IP0A 3NTGA 1L3YA 4BXWA 1ATDA 3ZYGA 4RRXA 3PGHA 2AYLA 1IJQA 1DIYA 4O1ZA 4CUFA 1ATEA 4NGAL 5IKRA 1FFMA 2W86A 3ZYJB 1EZQB 3GCWE 3CFWA 2KB9A 1A3PA 1KSNB 4Z6AL 1CCVA 2RNLA 1NFYB 4JZDL 1EMOA 4G1MB 3KK6A 4BTTA 5KN5C 2I9AA 5JVZA 3N8XA 2Q1JB 2Y5HL 1KLOA 2I9BA 3HS5A 2FLBL 2J95B 1NQLB 2ADXA 1FAKL 2Y7ZB 2Y80B 1G1QA 1EPJA 1SZBA 1RFNB 3N8ZA 4XLWA 1NPEB 1IQFL 2BZ6L 1KIGL 3HS6A 5IKVA 3GISX 2RHPA 1EBVA 2PUQL 2MHPA 1F7MA 1HT8A 3HS7A 2RA0L 1IOEL 1GK5A 3IJEB 2J4IB 4A7IA 5F1AA 2XBVL 4AQTA 1WHEA 1AUTL 5E8DA 2VVCK 2Y5FL 5JW1A 5JVYA 3H5CB 4M10A 2K2TA 1MOXC 1U8CB 1EPGA 4RUTA 2VVVL 2P95L 1APOA 4TGFA 5F19A 1PRHA 3LAQA 3FFGL 5COXA 3Q7DA 1NFUB 3NTBA 4MMYB 4CUEA 3KQBL 3POYA 5JBCE 5KIRA 4ISIL 2P94L 1WHFA 5JBBE 2KV4A 2W26B 1ZAQA 5L30L 1CVUA 2W3KB 1ATBA 3U73A 2EI6B 1TLEA 2UWOB 2UWLB 3SOBB 2WPLE 2G00L 3KQEL 1G1TA 1APQA 4D90A 4NA9L 1W8BL 6COXA 2WYJB 2M74A 3OLTA 2FD6A 1QFKL 1JV2B 1NFWB 1IQGL 1HT5A 1YUGA 2OYEP 1UZJA 3KQCL 1FF7A 2BQ7A 1EPHA 1P9JA 4O02B 1IGZA 3IITB 2FLRL 1NFXB 1J9CL 1TOZA 3NJPC 5CKMA 4D0EA 1LPKA 4Y7AB 2JKHL 2D1JB 1U67A 1G2LB 1EQGA 2XC0L 2VWLL 1IQNL 4JYUL 5JB8E 1L5GB 2WG4B 1HAEA 2VH6B 4BDXA 4Y71B 3N8YA 2W2NE 1HX2A 3N8WA 3CENL 4Y7BB 4C16A 1CVWL 4OTJA 2WPJE 2P28B 1M1XB 1W7XL 2BQ6A 4JZEL 4JZFL 5JB9E 4D0FA 1DDXA 1JBUL 4Z0LA 2EI8B 5CKQA 4BDWA 3BPSE 4YT7L 4ZXYL 2PHBB 5L2YL 2VWOL 2P3FN 2TGFA 1UZQA 1Q4GA 4NG9L 1LMJA 4RRZA 3ZYIB 1IOXA 3M37L 1YUFA 1NZIA 2VVUL 1XKAL 3TZIA 1F0RB 1YGCL 2Y82B 1IQJL 1V3XB 1IQLL 1BF9A 2XC4L 1IQEL 3HO5A 4CUDA 2B7DL 2UWPB 2OYUP 1DX5I 1YUKB 4COXA 2W3IB 3BT2A 4BTIA 3QMOA 1TPGA 4JYVL 1IQML 3FCSB 3LN0A 3NT1A 3TH3L
chains in the Genus database with same CATH superfamily
3TK5B 2WFXB 2BOKL 4Z0KB 2J94B 3P5BL 3QCWA 2FZZL 3K9XA 5FDQA 3GCXE 1N7DA 3KQDL 3LTFB 3V64C 1HRFA 1HCGB 3ENSA 1PTHA 1Z6EL 1X7AL 1PGEA 2YGPA 3F6UL 4LMFA 4RRWA 4YZUB 4XL1A 2FLGA 3QH0A 5JBAE 3TGFA 1EQHA 4Y79B 4PH9A 1IQIL 2EI7B 4CSYA 5EGMB 1JL9A 3U7UG 1PFXL 3TBDA 2BQWA 1KLJL 1PXXA 3R05A 3KCGL 4X8VL 1CCFA 3CA7A 3HPTA 2P93L 2MGRA 3SOVA 3MQEA 1IVOC 4Y6DB 1ADXA 3N8WB 2XBWL 3HO3A 2KL7A 1EMNA 4XBMA 2P3UA 3KRKA 4ZHAB 5IKTA 1DVAL 3TK6B 1NT0A 5IKQA 1CQEA 1LPZA 1UZKA 1K36A 2Y38A 3F1SB 5CKNA 2WPHE 4MMXB 2WPKE 1IQHL 3EGFA 1P0SL 5K0HB 2J38B 1MQ6L 2VJ3A 3N8YB 3Q3KB 1B9WA 4ZXXL 2K2SB 2P3TA 2W2ME 1HAFA 1ATAA 3MDLA 3LIWB 4ZAEB 4RRYA 3DEMA 2VWNL 1LQDA 2WPME 2WFTA 1UZPA 2DDUA 2BOXA 4ZH8B 2MGPA 2VWMK 1K37A 2XC5L 3CS7L 1XFEA 3C9AC 2CJIB 3RR3A 1N1IA 2W2QE 2XBXL 1EAIC 3BT1A 1FE2A 4ISHL 2BSFA 2J2UB 1CX2A 2F9BL 4YT6L 3SW2A 4LORA 4FM5A 5I46L 2WZPP 1XKBA 4BTUA 1CEJA 1FSBA 2Y7XB 1Z6CA 5L2ZL 3S6XA 1FAXL 2P16L 4RS0A 1G1SA 3KL6B 2WYGB 4MMZB 2J34B 1LPGA 4GU4A 2YGQA 1FJSL 2Y81B 2BO2A 2W2PE 2YGOA 1O5DL 3LC3B 3LN1A 3M36L 2NPRA 2Y5GL 1COUA 2BMGA 3LC5B 2XBYL 2BOUA 3FBYA 2WPIE 1YO8A 1EGFA 2BOHA 5CISA 1DQBA 1MQ5L 1C5MF 4X8TL 1WU1B 2VH0B 1URKA 3SOQA 3ASIA 4E1GA 4Y76B 1IGXA 1OB1C 4X8SL 2W2OE 3LTGD 1EPIA 2PR3B 1HJ7A 2P3FL 1I0UA 1HREA 3OLUA 3V65B 1IQKL 4BXSA 4M11A 1KLIL 1G1RA 1HZ8A 1XDTR 2WG3C 1F7EA 2H9EL 2HORA 3HO4A 1F0SB 3ELAL 4X8UL 2GD4A 1G2MB 4OTYA 2H9EC 3N8VA 2P26A 1IP0A 2VRSA 3NTGA 1L3YA 4BXWA 1ATDA 3ZYGA 2KNIA 4RRXA 3PGHA 2AYLA 1IJQA 1DIYA 4O1ZA 4CUFA 1ATEA 4NGAL 5IKRA 1FFMA 2W86A 3ZYJB 1EZQB 3GCWE 3CFWA 2KB9A 1A3PA 1KSNB 4Z6AL 1CCVA 2RNLA 1NFYB 4JZDL 1V1HA 4GU3A 1EMOA 4G1MB 3KK6A 4BTTA 5KN5C 2I9AA 5JVZA 3N8XA 2Q1JB 2Y5HL 1KLOA 2I9BA 3HS5A 2FLBL 2J95B 1NQLB 2ADXA 1FAKL 2Y7ZB 2Y80B 1G1QA 1EPJA 1SZBA 1RFNB 3N8ZA 4XLWA 1NPEB 1IQFL 2BZ6L 1KIGL 3HS6A 5IKVA 3GISX 2RHPA 1EBVA 2PUQL 2MHPA 1F7MA 1HT8A 3HS7A 2RA0L 1IOEL 1GK5A 3IJEB 2J4IB 4A7IA 5F1AA 2XBVL 4AQTA 1WHEA 1AUTL 5E8DA 2VVCK 2Y5FL 5JW1A 5JVYA 3H5CB 4M10A 2K2TA 1MOXC 1U8CB 1EPGA 4RUTA 2VVVL 2P95L 1APOA 4TGFA 5F19A 1PRHA 3LAQA 1LK9A 3FFGL 5COXA 3Q7DA 1NFUB 3NTBA 4MMYB 4CUEA 3KQBL 3POYA 5JBCE 5KIRA 4ISIL 2P94L 1WHFA 5JBBE 2KV4A 2W26B 1ZAQA 5L30L 1CVUA 2W3KB 1ATBA 2BT7A 3U73A 2EI6B 1TLEA 2UWOB 2UWLB 3SOBB 2WPLE 2G00L 3KQEL 1G1TA 1APQA 4D90A 1V1IA 4NA9L 1W8BL 6COXA 2WYJB 2M74A 3OLTA 2FD6A 1QFKL 1JV2B 1NFWB 1IQGL 1HT5A 1YUGA 2OYEP 1UZJA 3KQCL 1FF7A 2BQ7A 1EPHA 1P9JA 4O02B 1IGZA 3IITB 1KKEA 2FLRL 1NFXB 1J9CL 1TOZA 3NJPC 5CKMA 4D0EA 1LPKA 4Y7AB 2JKHL 2D1JB 1U67A 1G2LB 1EQGA 1QIUA 2XC0L 2VWLL 1IQNL 4JYUL 5JB8E 1LMMA 1L5GB 2WG4B 1HAEA 2VH6B 4A94C 4BDXA 4Y71B 3N8YA 2W2NE 1HX2A 3N8WA 3CENL 4Y7BB 4C16A 1CVWL 4OTJA 2WPJE 2P28B 1M1XB 1W7XL 2BQ6A 4JZEL 4JZFL 5JB9E 4D0FA 2HOXA 1DDXA 1JBUL 4Z0LA 2EI8B 5CKQA 4BDWA 3BPSE 2BT8A 4YT7L 4ZXYL 2PHBB 5L2YL 2VWOL 2P3FN 2TGFA 1UZQA 1Q4GA 4NG9L 1LMJA 4RRZA 3ZYIB 1IOXA 3M37L 1YUFA 1NZIA 2VVUL 1XKAL 3TZIA 2Y82B 1F0RB 1YGCL 1IQJL 1V3XB 1IQLL 1BF9A 2XC4L 1IQEL 3HO5A 4CUDA 2B7DL 2UWPB 2OYUP 1DX5I 1YUKB 4COXA 2W3IB 3BT2A 4BTIA 3QMOA 1TPGA 4JYVL 1IQML 2JJLA 3FCSB 3LN0A 3NT1A 3TH3L
chains in the Genus database with same CATH topology
3TK5B 2WFXB 2BOKL 4Z0KB 2J94B 3P5BL 3QCWA 2FZZL 3K9XA 5FDQA 3GCXE 1N7DA 3KQDL 3LTFB 3V64C 1HRFA 1HCGB 3ENSA 1PTHA 1Z6EL 1X7AL 1PGEA 2YGPA 3F6UL 4LMFA 4RRWA 4YZUB 4XL1A 2FLGA 3QH0A 5JBAE 3TGFA 1EQHA 4Y79B 4PH9A 1IQIL 2EI7B 4CSYA 5EGMB 1JL9A 3U7UG 1PFXL 3TBDA 2BQWA 1KLJL 1PXXA 3R05A 3KCGL 4X8VL 1CCFA 3CA7A 3HPTA 2P93L 2MGRA 3SOVA 3MQEA 1IVOC 4Y6DB 1ADXA 3N8WB 2XBWL 3HO3A 2KL7A 1EMNA 4XBMA 2P3UA 3KRKA 4ZHAB 5IKTA 1DVAL 3TK6B 1NT0A 5IKQA 1CQEA 1LPZA 1UZKA 1K36A 2Y38A 3F1SB 5CKNA 2WPHE 4MMXB 2WPKE 1IQHL 3EGFA 1P0SL 5K0HB 2J38B 1MQ6L 2VJ3A 3N8YB 3Q3KB 1B9WA 4ZXXL 2K2SB 2P3TA 2W2ME 1HAFA 1ATAA 3MDLA 3LIWB 4ZAEB 4RRYA 3DEMA 2VWNL 1LQDA 2WPME 2WFTA 1UZPA 2DDUA 2BOXA 4ZH8B 2MGPA 2VWMK 1K37A 2XC5L 3CS7L 1XFEA 3C9AC 2CJIB 3RR3A 1N1IA 2W2QE 2XBXL 1EAIC 3BT1A 1FE2A 4ISHL 2J2UB 1CX2A 2F9BL 4YT6L 3SW2A 4LORA 4FM5A 5I46L 2WZPP 1XKBA 4BTUA 1CEJA 1FSBA 2Y7XB 1Z6CA 5L2ZL 3S6XA 1FAXL 2P16L 4RS0A 1G1SA 3KL6B 2WYGB 4MMZB 2J34B 1LPGA 2YGQA 1FJSL 2Y81B 2BO2A 2W2PE 2YGOA 1O5DL 3LC3B 3LN1A 3M36L 2NPRA 2Y5GL 1COUA 2BMGA 3LC5B 2XBYL 2BOUA 3FBYA 2WPIE 1YO8A 1EGFA 2BOHA 5CISA 1DQBA 1MQ5L 1C5MF 4X8TL 1WU1B 2VH0B 1URKA 3SOQA 3ASIA 4E1GA 4Y76B 1IGXA 1OB1C 4X8SL 2W2OE 3LTGD 1EPIA 2PR3B 1HJ7A 2P3FL 1I0UA 1HREA 3OLUA 3V65B 1IQKL 4BXSA 4M11A 1KLIL 1G1RA 1HZ8A 1XDTR 2WG3C 1F7EA 2H9EL 3HO4A 1F0SB 3ELAL 4X8UL 2GD4A 1G2MB 4OTYA 2H9EC 3N8VA 2P26A 1IP0A 3NTGA 1L3YA 4BXWA 1ATDA 3ZYGA 2KNIA 4RRXA 3PGHA 2AYLA 1IJQA 1DIYA 4O1ZA 4CUFA 1ATEA 4NGAL 5IKRA 1FFMA 2W86A 3ZYJB 1EZQB 3GCWE 3CFWA 2KB9A 1A3PA 1KSNB 4Z6AL 1CCVA 2RNLA 1NFYB 4JZDL 1EMOA 4G1MB 3KK6A 4BTTA 5KN5C 2I9AA 5JVZA 3N8XA 2Q1JB 2Y5HL 1KLOA 2I9BA 3HS5A 2FLBL 2J95B 1NQLB 2ADXA 1FAKL 2Y7ZB 2Y80B 1G1QA 1EPJA 1SZBA 1RFNB 3N8ZA 4XLWA 1NPEB 1IQFL 2BZ6L 1KIGL 3HS6A 5IKVA 3GISX 2RHPA 1EBVA 2PUQL 2MHPA 1F7MA 1HT8A 3HS7A 2RA0L 1IOEL 1GK5A 3IJEB 2J4IB 4A7IA 5F1AA 2XBVL 4AQTA 1WHEA 1AUTL 5E8DA 2VVCK 2Y5FL 5JW1A 5JVYA 3H5CB 4M10A 2K2TA 1MOXC 1U8CB 1EPGA 4RUTA 2VVVL 2P95L 1APOA 4TGFA 5F19A 1PRHA 3LAQA 3FFGL 5COXA 3Q7DA 1NFUB 3NTBA 4MMYB 4CUEA 3KQBL 3POYA 5JBCE 5KIRA 4ISIL 2P94L 1WHFA 5JBBE 2KV4A 2W26B 1ZAQA 5L30L 1CVUA 2W3KB 1ATBA 3U73A 2EI6B 1TLEA 2UWOB 2UWLB 3SOBB 2WPLE 2G00L 3KQEL 1G1TA 1APQA 4D90A 4NA9L 1W8BL 6COXA 2WYJB 2M74A 3OLTA 2FD6A 1QFKL 1JV2B 1NFWB 1IQGL 1HT5A 1YUGA 2OYEP 1UZJA 3KQCL 1FF7A 2BQ7A 1EPHA 1P9JA 4O02B 1IGZA 3IITB 2FLRL 1NFXB 1J9CL 1TOZA 3NJPC 5CKMA 4D0EA 1LPKA 4Y7AB 2JKHL 2D1JB 1U67A 1G2LB 1EQGA 2XC0L 2VWLL 1IQNL 4JYUL 5JB8E 1LMMA 1L5GB 2WG4B 1HAEA 2VH6B 4A94C 4BDXA 4Y71B 3N8YA 2W2NE 1HX2A 3N8WA 3CENL 4Y7BB 4C16A 1CVWL 4OTJA 2WPJE 2P28B 1M1XB 1W7XL 2BQ6A 4JZEL 4JZFL 5JB9E 4D0FA 1DDXA 1JBUL 4Z0LA 2EI8B 5CKQA 4BDWA 3BPSE 4YT7L 4ZXYL 2PHBB 5L2YL 2VWOL 2P3FN 2TGFA 1UZQA 1Q4GA 4NG9L 1LMJA 4RRZA 3ZYIB 1IOXA 3M37L 1YUFA 1NZIA 2VVUL 1XKAL 3TZIA 2Y82B 1F0RB 1YGCL 1IQJL 1V3XB 1IQLL 1BF9A 2XC4L 1IQEL 3HO5A 4CUDA 2B7DL 2UWPB 2OYUP 1DX5I 1YUKB 4COXA 2W3IB 3BT2A 4BTIA 3QMOA 1TPGA 4JYVL 1IQML 3FCSB 3LN0A 3NT1A 3TH3L
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3TK5 B;  2WFX B;  2BOK L;  4Z0K B;  2J94 B;  3P5B L;  3QCW A;  2FZZ L;  3K9X A;  5FDQ A;  3GCX E;  1N7D A;  3KQD L;  3LTF B;  3V64 C;  1HRF A;  1HCG B;  3ENS A;  1PTH A;  1Z6E L;  1X7A L;  1PGE A;  2YGP A;  3F6U L;  4LMF A;  4RRW A;  4YZU B;  4XL1 A;  2FLG A;  3QH0 A;  5JBA E;  3TGF A;  1EQH A;  4Y79 B;  4PH9 A;  1IQI L;  2EI7 B;  4CSY A;  5EGM B;  1JL9 A;  3U7U G;  1PFX L;  3TBD A;  2BQW A;  1KLJ L;  1PXX A;  3R05 A;  3KCG L;  4X8V L;  1CCF A;  3CA7 A;  3HPT A;  2P93 L;  2MGR A;  3SOV A;  3MQE A;  1IVO C;  4Y6D B;  1ADX A;  3N8W B;  2XBW L;  3HO3 A;  2KL7 A;  1EMN A;  4XBM A;  2P3U A;  3KRK A;  4ZHA B;  5IKT A;  1DVA L;  3TK6 B;  1NT0 A;  5IKQ A;  1CQE A;  1LPZ A;  1UZK A;  1K36 A;  2Y38 A;  3F1S B;  5CKN A;  2WPH E;  4MMX B;  2WPK E;  1IQH L;  3EGF A;  1P0S L;  5K0H B;  2J38 B;  1MQ6 L;  2VJ3 A;  3N8Y B;  3Q3K B;  1B9W A;  4ZXX L;  2K2S B;  2P3T A;  2W2M E;  1HAF A;  1ATA A;  3MDL A;  3LIW B;  4ZAE B;  4RRY A;  3DEM A;  2VWN L;  1LQD A;  2WPM E;  2WFT A;  1UZP A;  2DDU A;  2BOX A;  4ZH8 B;  2MGP A;  2VWM K;  1K37 A;  2XC5 L;  3CS7 L;  1XFE A;  3C9A C;  2CJI B;  3RR3 A;  1N1I A;  2W2Q E;  2XBX L;  1EAI C;  3BT1 A;  1FE2 A;  4ISH L;  2J2U B;  1CX2 A;  2F9B L;  4YT6 L;  3SW2 A;  4LOR A;  4FM5 A;  5I46 L;  1XKB A;  4BTU A;  1CEJ A;  1FSB A;  2Y7X B;  1Z6C A;  5L2Z L;  1FAX L;  2P16 L;  4RS0 A;  1G1S A;  3KL6 B;  2WYG B;  4MMZ B;  2J34 B;  1LPG A;  1FJS L;  2Y81 B;  2BO2 A;  2W2P E;  2YGO A;  1O5D L;  3LC3 B;  3LN1 A;  3M36 L;  2NPR A;  2Y5G L;  1COU A;  2BMG A;  3LC5 B;  2XBY L;  2BOU A;  3FBY A;  2WPI E;  1YO8 A;  1EGF A;  2BOH A;  5CIS A;  1DQB A;  1MQ5 L;  1C5M F;  4X8T L;  1WU1 B;  2VH0 B;  1URK A;  3SOQ A;  3ASI A;  4E1G A;  4Y76 B;  1IGX A;  1OB1 C;  4X8S L;  2W2O E;  3LTG D;  1EPI A;  2PR3 B;  1HJ7 A;  2P3F L;  1I0U A;  1HRE A;  3OLU A;  3V65 B;  1IQK L;  4BXS A;  4M11 A;  1KLI L;  1G1R A;  1HZ8 A;  1XDT R;  2WG3 C;  1F7E A;  2H9E L;  3HO4 A;  1F0S B;  3ELA L;  4X8U L;  2GD4 A;  1G2M B;  4OTY A;  3N8V A;  2P26 A;  1IP0 A;  3NTG A;  1L3Y A;  4BXW A;  1ATD A;  3ZYG A;  4RRX A;  3PGH A;  2AYL A;  1IJQ A;  1DIY A;  4O1Z A;  4CUF A;  1ATE A;  4NGA L;  5IKR A;  1FFM A;  2W86 A;  3ZYJ B;  1EZQ B;  3GCW E;  3CFW A;  2KB9 A;  1A3P A;  1KSN B;  4Z6A L;  1CCV A;  2RNL A;  1NFY B;  4JZD L;  1EMO A;  4G1M B;  3KK6 A;  4BTT A;  5KN5 C;  2I9A A;  5JVZ A;  3N8X A;  2Q1J B;  2Y5H L;  1KLO A;  2I9B A;  3HS5 A;  2FLB L;  2J95 B;  1NQL B;  2ADX A;  1FAK L;  2Y7Z B;  2Y80 B;  1G1Q A;  1EPJ A;  1SZB A;  1RFN B;  3N8Z A;  4XLW A;  1NPE B;  1IQF L;  2BZ6 L;  1KIG L;  3HS6 A;  5IKV A;  3GIS X;  2RHP A;  1EBV A;  2PUQ L;  2MHP A;  1F7M A;  1HT8 A;  3HS7 A;  2RA0 L;  1IOE L;  1GK5 A;  3IJE B;  2J4I B;  4A7I A;  5F1A A;  2XBV L;  4AQT A;  1WHE A;  1AUT L;  5E8D A;  2VVC K;  2Y5F L;  5JW1 A;  5JVY A;  3H5C B;  4M10 A;  2K2T A;  1MOX C;  1U8C B;  1EPG A;  4RUT A;  2VVV L;  2P95 L;  1APO A;  4TGF A;  5F19 A;  1PRH A;  3LAQ A;  3FFG L;  5COX A;  3Q7D A;  1NFU B;  3NTB A;  4MMY B;  4CUE A;  3KQB L;  3POY A;  5JBC E;  5KIR A;  4ISI L;  2P94 L;  1WHF A;  5JBB E;  2KV4 A;  2W26 B;  1ZAQ A;  5L30 L;  1CVU A;  2W3K B;  1ATB A;  3U73 A;  2EI6 B;  1TLE A;  2UWO B;  2UWL B;  3SOB B;  2WPL E;  2G00 L;  3KQE L;  1G1T A;  1APQ A;  4D90 A;  4NA9 L;  1W8B L;  6COX A;  2WYJ B;  2M74 A;  3OLT A;  2FD6 A;  1QFK L;  1JV2 B;  1NFW B;  1IQG L;  1HT5 A;  1YUG A;  2OYE P;  1UZJ A;  3KQC L;  1FF7 A;  2BQ7 A;  1EPH A;  1P9J A;  4O02 B;  1IGZ A;  3IIT B;  2FLR L;  1NFX B;  1J9C L;  1TOZ A;  3NJP C;  5CKM A;  4D0E A;  1LPK A;  4Y7A B;  2JKH L;  2D1J B;  1U67 A;  1G2L B;  1EQG A;  2XC0 L;  2VWL L;  1IQN L;  4JYU L;  5JB8 E;  1L5G B;  2WG4 B;  1HAE A;  2VH6 B;  4BDX A;  4Y71 B;  3N8Y A;  2W2N E;  1HX2 A;  3N8W A;  3CEN L;  4Y7B B;  4C16 A;  1CVW L;  4OTJ A;  2WPJ E;  2P28 B;  1M1X B;  1W7X L;  2BQ6 A;  4JZE L;  4JZF L;  5JB9 E;  4D0F A;  1DDX A;  1JBU L;  4Z0L A;  2EI8 B;  5CKQ A;  4BDW A;  3BPS E;  4YT7 L;  4ZXY L;  2PHB B;  5L2Y L;  2VWO L;  2P3F N;  2TGF A;  1UZQ A;  1Q4G A;  4NG9 L;  1LMJ A;  4RRZ A;  3ZYI B;  1IOX A;  3M37 L;  1YUF A;  1NZI A;  2VVU L;  1XKA L;  3TZI A;  1F0R B;  1YGC L;  2Y82 B;  1IQJ L;  1V3X B;  1IQL L;  1BF9 A;  2XC4 L;  1IQE L;  3HO5 A;  4CUD A;  2B7D L;  2UWP B;  2OYU P;  1DX5 I;  1YUK B;  4COX A;  2W3I B;  3BT2 A;  4BTI A;  3QMO A;  1TPG A;  4JYV L;  1IQM L;  3FCS B;  3LN0 A;  3NT1 A;  3TH3 L; 
#chains in the Genus database with same CATH topology
 3TK5 B;  2WFX B;  2BOK L;  4Z0K B;  2J94 B;  3P5B L;  3QCW A;  2FZZ L;  3K9X A;  5FDQ A;  3GCX E;  1N7D A;  3KQD L;  3LTF B;  3V64 C;  1HRF A;  1HCG B;  3ENS A;  1PTH A;  1Z6E L;  1X7A L;  1PGE A;  2YGP A;  3F6U L;  4LMF A;  4RRW A;  4YZU B;  4XL1 A;  2FLG A;  3QH0 A;  5JBA E;  3TGF A;  1EQH A;  4Y79 B;  4PH9 A;  1IQI L;  2EI7 B;  4CSY A;  5EGM B;  1JL9 A;  3U7U G;  1PFX L;  3TBD A;  2BQW A;  1KLJ L;  1PXX A;  3R05 A;  3KCG L;  4X8V L;  1CCF A;  3CA7 A;  3HPT A;  2P93 L;  2MGR A;  3SOV A;  3MQE A;  1IVO C;  4Y6D B;  1ADX A;  3N8W B;  2XBW L;  3HO3 A;  2KL7 A;  1EMN A;  4XBM A;  2P3U A;  3KRK A;  4ZHA B;  5IKT A;  1DVA L;  3TK6 B;  1NT0 A;  5IKQ A;  1CQE A;  1LPZ A;  1UZK A;  1K36 A;  2Y38 A;  3F1S B;  5CKN A;  2WPH E;  4MMX B;  2WPK E;  1IQH L;  3EGF A;  1P0S L;  5K0H B;  2J38 B;  1MQ6 L;  2VJ3 A;  3N8Y B;  3Q3K B;  1B9W A;  4ZXX L;  2K2S B;  2P3T A;  2W2M E;  1HAF A;  1ATA A;  3MDL A;  3LIW B;  4ZAE B;  4RRY A;  3DEM A;  2VWN L;  1LQD A;  2WPM E;  2WFT A;  1UZP A;  2DDU A;  2BOX A;  4ZH8 B;  2MGP A;  2VWM K;  1K37 A;  2XC5 L;  3CS7 L;  1XFE A;  3C9A C;  2CJI B;  3RR3 A;  1N1I A;  2W2Q E;  2XBX L;  1EAI C;  3BT1 A;  1FE2 A;  4ISH L;  2BSF A;  2J2U B;  1CX2 A;  2F9B L;  4YT6 L;  3SW2 A;  4LOR A;  4FM5 A;  5I46 L;  2WZP P;  1XKB A;  4BTU A;  1CEJ A;  1FSB A;  2Y7X B;  1Z6C A;  5L2Z L;  3S6X A;  1FAX L;  2P16 L;  4RS0 A;  1G1S A;  3KL6 B;  2WYG B;  4MMZ B;  2J34 B;  1LPG A;  4GU4 A;  2YGQ A;  1FJS L;  2Y81 B;  2BO2 A;  2W2P E;  2YGO A;  1O5D L;  3LC3 B;  3LN1 A;  3M36 L;  2NPR A;  2Y5G L;  1COU A;  2BMG A;  3LC5 B;  2XBY L;  2BOU A;  3FBY A;  2WPI E;  1YO8 A;  1EGF A;  2BOH A;  5CIS A;  1DQB A;  1MQ5 L;  1C5M F;  4X8T L;  1WU1 B;  2VH0 B;  1URK A;  3SOQ A;  3ASI A;  4E1G A;  4Y76 B;  1IGX A;  1OB1 C;  4X8S L;  2W2O E;  3LTG D;  1EPI A;  2PR3 B;  1HJ7 A;  2P3F L;  1I0U A;  1HRE A;  3OLU A;  3V65 B;  1IQK L;  4BXS A;  4M11 A;  1KLI L;  1G1R A;  1HZ8 A;  1XDT R;  2WG3 C;  1F7E A;  2H9E L;  2HOR A;  3HO4 A;  1F0S B;  3ELA L;  4X8U L;  2GD4 A;  1G2M B;  4OTY A;  2H9E C;  3N8V A;  2P26 A;  1IP0 A;  2VRS A;  3NTG A;  1L3Y A;  4BXW A;  1ATD A;  3ZYG A;  2KNI A;  4RRX A;  3PGH A;  2AYL A;  1IJQ A;  1DIY A;  4O1Z A;  4CUF A;  1ATE A;  4NGA L;  5IKR A;  1FFM A;  2W86 A;  3ZYJ B;  1EZQ B;  3GCW E;  3CFW A;  2KB9 A;  1A3P A;  1KSN B;  4Z6A L;  1CCV A;  2RNL A;  1NFY B;  4JZD L;  1V1H A;  4GU3 A;  1EMO A;  4G1M B;  3KK6 A;  4BTT A;  5KN5 C;  2I9A A;  5JVZ A;  3N8X A;  2Q1J B;  2Y5H L;  1KLO A;  2I9B A;  3HS5 A;  2FLB L;  2J95 B;  1NQL B;  2ADX A;  1FAK L;  2Y7Z B;  2Y80 B;  1G1Q A;  1EPJ A;  1SZB A;  1RFN B;  3N8Z A;  4XLW A;  1NPE B;  1IQF L;  2BZ6 L;  1KIG L;  3HS6 A;  5IKV A;  3GIS X;  2RHP A;  1EBV A;  2PUQ L;  2MHP A;  1F7M A;  1HT8 A;  3HS7 A;  2RA0 L;  1IOE L;  1GK5 A;  3IJE B;  2J4I B;  4A7I A;  5F1A A;  2XBV L;  4AQT A;  1WHE A;  1AUT L;  5E8D A;  2VVC K;  2Y5F L;  5JW1 A;  5JVY A;  3H5C B;  4M10 A;  2K2T A;  1MOX C;  1U8C B;  1EPG A;  4RUT A;  2VVV L;  2P95 L;  1APO A;  4TGF A;  5F19 A;  1PRH A;  3LAQ A;  1LK9 A;  3FFG L;  5COX A;  3Q7D A;  1NFU B;  3NTB A;  4MMY B;  4CUE A;  3KQB L;  3POY A;  5JBC E;  5KIR A;  4ISI L;  2P94 L;  1WHF A;  5JBB E;  2KV4 A;  2W26 B;  1ZAQ A;  5L30 L;  1CVU A;  2W3K B;  1ATB A;  2BT7 A;  3U73 A;  2EI6 B;  1TLE A;  2UWO B;  2UWL B;  3SOB B;  2WPL E;  2G00 L;  3KQE L;  1G1T A;  1APQ A;  4D90 A;  1V1I A;  4NA9 L;  1W8B L;  6COX A;  2WYJ B;  2M74 A;  3OLT A;  2FD6 A;  1QFK L;  1JV2 B;  1NFW B;  1IQG L;  1HT5 A;  1YUG A;  2OYE P;  1UZJ A;  3KQC L;  1FF7 A;  2BQ7 A;  1EPH A;  1P9J A;  4O02 B;  1IGZ A;  3IIT B;  1KKE A;  2FLR L;  1NFX B;  1J9C L;  1TOZ A;  3NJP C;  5CKM A;  4D0E A;  1LPK A;  4Y7A B;  2JKH L;  2D1J B;  1U67 A;  1G2L B;  1EQG A;  1QIU A;  2XC0 L;  2VWL L;  1IQN L;  4JYU L;  5JB8 E;  1LMM A;  1L5G B;  2WG4 B;  1HAE A;  2VH6 B;  4A94 C;  4BDX A;  4Y71 B;  3N8Y A;  2W2N E;  1HX2 A;  3N8W A;  3CEN L;  4Y7B B;  4C16 A;  1CVW L;  4OTJ A;  2WPJ E;  2P28 B;  1M1X B;  1W7X L;  2BQ6 A;  4JZE L;  4JZF L;  5JB9 E;  4D0F A;  2HOX A;  1DDX A;  1JBU L;  4Z0L A;  2EI8 B;  5CKQ A;  4BDW A;  3BPS E;  2BT8 A;  4YT7 L;  4ZXY L;  2PHB B;  5L2Y L;  2VWO L;  2P3F N;  2TGF A;  1UZQ A;  1Q4G A;  4NG9 L;  1LMJ A;  4RRZ A;  3ZYI B;  1IOX A;  3M37 L;  1YUF A;  1NZI A;  2VVU L;  1XKA L;  3TZI A;  2Y82 B;  1F0R B;  1YGC L;  1IQJ L;  1V3X B;  1IQL L;  1BF9 A;  2XC4 L;  1IQE L;  3HO5 A;  4CUD A;  2B7D L;  2UWP B;  2OYU P;  1DX5 I;  1YUK B;  4COX A;  2W3I B;  3BT2 A;  4BTI A;  3QMO A;  1TPG A;  4JYV L;  1IQM L;  2JJL A;  3FCS B;  3LN0 A;  3NT1 A;  3TH3 L; 
#chains in the Genus database with same CATH homology
 3TK5 B;  2WFX B;  2BOK L;  4Z0K B;  2J94 B;  3P5B L;  3QCW A;  2FZZ L;  3K9X A;  5FDQ A;  3GCX E;  1N7D A;  3KQD L;  3LTF B;  3V64 C;  1HRF A;  1HCG B;  3ENS A;  1PTH A;  1Z6E L;  1X7A L;  1PGE A;  2YGP A;  3F6U L;  4LMF A;  4RRW A;  4YZU B;  4XL1 A;  2FLG A;  3QH0 A;  5JBA E;  3TGF A;  1EQH A;  4Y79 B;  4PH9 A;  1IQI L;  2EI7 B;  4CSY A;  5EGM B;  1JL9 A;  3U7U G;  1PFX L;  3TBD A;  2BQW A;  1KLJ L;  1PXX A;  3R05 A;  3KCG L;  4X8V L;  1CCF A;  3CA7 A;  3HPT A;  2P93 L;  2MGR A;  3SOV A;  3MQE A;  1IVO C;  4Y6D B;  1ADX A;  3N8W B;  2XBW L;  3HO3 A;  2KL7 A;  1EMN A;  4XBM A;  2P3U A;  3KRK A;  4ZHA B;  5IKT A;  1DVA L;  3TK6 B;  1NT0 A;  5IKQ A;  1CQE A;  1LPZ A;  1UZK A;  1K36 A;  2Y38 A;  3F1S B;  5CKN A;  2WPH E;  4MMX B;  2WPK E;  1IQH L;  3EGF A;  1P0S L;  5K0H B;  2J38 B;  1MQ6 L;  2VJ3 A;  3N8Y B;  3Q3K B;  1B9W A;  4ZXX L;  2K2S B;  2P3T A;  2W2M E;  1HAF A;  1ATA A;  3MDL A;  3LIW B;  4ZAE B;  4RRY A;  3DEM A;  2VWN L;  1LQD A;  2WPM E;  2WFT A;  1UZP A;  2DDU A;  2BOX A;  4ZH8 B;  2MGP A;  2VWM K;  1K37 A;  2XC5 L;  3CS7 L;  1XFE A;  3C9A C;  2CJI B;  3RR3 A;  1N1I A;  2W2Q E;  2XBX L;  1EAI C;  3BT1 A;  1FE2 A;  4ISH L;  2J2U B;  1CX2 A;  2F9B L;  4YT6 L;  3SW2 A;  4LOR A;  4FM5 A;  5I46 L;  2WZP P;  1XKB A;  4BTU A;  1CEJ A;  1FSB A;  2Y7X B;  1Z6C A;  5L2Z L;  3S6X A;  1FAX L;  2P16 L;  4RS0 A;  1G1S A;  3KL6 B;  2WYG B;  4MMZ B;  2J34 B;  1LPG A;  2YGQ A;  1FJS L;  2Y81 B;  2BO2 A;  2W2P E;  2YGO A;  1O5D L;  3LC3 B;  3LN1 A;  3M36 L;  2NPR A;  2Y5G L;  1COU A;  2BMG A;  3LC5 B;  2XBY L;  2BOU A;  3FBY A;  2WPI E;  1YO8 A;  1EGF A;  2BOH A;  5CIS A;  1DQB A;  1MQ5 L;  1C5M F;  4X8T L;  1WU1 B;  2VH0 B;  1URK A;  3SOQ A;  3ASI A;  4E1G A;  4Y76 B;  1IGX A;  1OB1 C;  4X8S L;  2W2O E;  3LTG D;  1EPI A;  2PR3 B;  1HJ7 A;  2P3F L;  1I0U A;  1HRE A;  3OLU A;  3V65 B;  1IQK L;  4BXS A;  4M11 A;  1KLI L;  1G1R A;  1HZ8 A;  1XDT R;  2WG3 C;  1F7E A;  2H9E L;  3HO4 A;  1F0S B;  3ELA L;  4X8U L;  2GD4 A;  1G2M B;  4OTY A;  2H9E C;  3N8V A;  2P26 A;  1IP0 A;  3NTG A;  1L3Y A;  4BXW A;  1ATD A;  3ZYG A;  2KNI A;  4RRX A;  3PGH A;  2AYL A;  1IJQ A;  1DIY A;  4O1Z A;  4CUF A;  1ATE A;  4NGA L;  5IKR A;  1FFM A;  2W86 A;  3ZYJ B;  1EZQ B;  3GCW E;  3CFW A;  2KB9 A;  1A3P A;  1KSN B;  4Z6A L;  1CCV A;  2RNL A;  1NFY B;  4JZD L;  1EMO A;  4G1M B;  3KK6 A;  4BTT A;  5KN5 C;  2I9A A;  5JVZ A;  3N8X A;  2Q1J B;  2Y5H L;  1KLO A;  2I9B A;  3HS5 A;  2FLB L;  2J95 B;  1NQL B;  2ADX A;  1FAK L;  2Y7Z B;  2Y80 B;  1G1Q A;  1EPJ A;  1SZB A;  1RFN B;  3N8Z A;  4XLW A;  1NPE B;  1IQF L;  2BZ6 L;  1KIG L;  3HS6 A;  5IKV A;  3GIS X;  2RHP A;  1EBV A;  2PUQ L;  2MHP A;  1F7M A;  1HT8 A;  3HS7 A;  2RA0 L;  1IOE L;  1GK5 A;  3IJE B;  2J4I B;  4A7I A;  5F1A A;  2XBV L;  4AQT A;  1WHE A;  1AUT L;  5E8D A;  2VVC K;  2Y5F L;  5JW1 A;  5JVY A;  3H5C B;  4M10 A;  2K2T A;  1MOX C;  1U8C B;  1EPG A;  4RUT A;  2VVV L;  2P95 L;  1APO A;  4TGF A;  5F19 A;  1PRH A;  3LAQ A;  3FFG L;  5COX A;  3Q7D A;  1NFU B;  3NTB A;  4MMY B;  4CUE A;  3KQB L;  3POY A;  5JBC E;  5KIR A;  4ISI L;  2P94 L;  1WHF A;  5JBB E;  2KV4 A;  2W26 B;  1ZAQ A;  5L30 L;  1CVU A;  2W3K B;  1ATB A;  3U73 A;  2EI6 B;  1TLE A;  2UWO B;  2UWL B;  3SOB B;  2WPL E;  2G00 L;  3KQE L;  1G1T A;  1APQ A;  4D90 A;  4NA9 L;  1W8B L;  6COX A;  2WYJ B;  2M74 A;  3OLT A;  2FD6 A;  1QFK L;  1JV2 B;  1NFW B;  1IQG L;  1HT5 A;  1YUG A;  2OYE P;  1UZJ A;  3KQC L;  1FF7 A;  2BQ7 A;  1EPH A;  1P9J A;  4O02 B;  1IGZ A;  3IIT B;  2FLR L;  1NFX B;  1J9C L;  1TOZ A;  3NJP C;  5CKM A;  4D0E A;  1LPK A;  4Y7A B;  2JKH L;  2D1J B;  1U67 A;  1G2L B;  1EQG A;  2XC0 L;  2VWL L;  1IQN L;  4JYU L;  5JB8 E;  1LMM A;  1L5G B;  2WG4 B;  1HAE A;  2VH6 B;  4A94 C;  4BDX A;  4Y71 B;  3N8Y A;  2W2N E;  1HX2 A;  3N8W A;  3CEN L;  4Y7B B;  4C16 A;  1CVW L;  4OTJ A;  2WPJ E;  2P28 B;  1M1X B;  1W7X L;  2BQ6 A;  4JZE L;  4JZF L;  5JB9 E;  4D0F A;  1DDX A;  1JBU L;  4Z0L A;  2EI8 B;  5CKQ A;  4BDW A;  3BPS E;  4YT7 L;  4ZXY L;  2PHB B;  5L2Y L;  2VWO L;  2P3F N;  2TGF A;  1UZQ A;  1Q4G A;  4NG9 L;  1LMJ A;  4RRZ A;  3ZYI B;  1IOX A;  3M37 L;  1YUF A;  1NZI A;  2VVU L;  1XKA L;  3TZI A;  2Y82 B;  1F0R B;  1YGC L;  1IQJ L;  1V3X B;  1IQL L;  1BF9 A;  2XC4 L;  1IQE L;  3HO5 A;  4CUD A;  2B7D L;  2UWP B;  2OYU P;  1DX5 I;  1YUK B;  4COX A;  2W3I B;  3BT2 A;  4BTI A;  3QMO A;  1TPG A;  4JYV L;  1IQM L;  3FCS B;  3LN0 A;  3NT1 A;  3TH3 L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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