1MOXC

Crystal structure of human epidermal growth factor receptor (residues 1-501) in complex with tgf-alpha
Total Genus 6
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
6
sequence length
49
structure length
49
Chain Sequence
VSHFNDCPDSHTQFCFHGTCRFLVQEDKPACVCHSGYVGARCEHADLLA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of a Truncated Epidermal Growth Factor Receptor Extracellular Domain Bound to Transforming Growth Factor alpha
pubmed doi rcsb
molecule tags Transferase/growth factor
source organism Homo sapiens
molecule keywords Epidermal Growth Factor Receptor
total genus 6
structure length 49
sequence length 49
chains with identical sequence D
ec nomenclature
pdb deposition date 2002-09-10
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 1moxC00
1NFXB 4Y7AB 2RHPA 1IP0A 1F7MA 1EQHA 4RRYA 2FZZL 1MQ6L 5KIRA 2VH6B 2WYJB 5JBBE 2BZ6L 3GCWE 1TLEA 4BDWA 2BQ6A 3DEMA 1TPGA 2Y7ZB 5F1AA 2D1JB 3HO3A 5IKRA 4BDXA 2PR3B 2XC0L 3KL6B 1IOXA 1X7AL 3N8ZA 3TGFA 2J95B 5L2ZL 1HT8A 5FDQA 1AUTL 1G1TA 1EZQB 2BOHA 3IITB 4CUEA 5KN5C 1KLOA 4RRXA 3ZYGA 5IKTA 2J38B 1I0UA 2Y5GL 1YUFA 2KV4A 2VWMK 2Y38A 4YT7L 2WPKE 3ZYIB 1YO8A 1FAXL 2WG3C 2P3TA 1IQML 1IVOC 1ATEA 1EPGA 2P3UA 2WPLE 1C5MF 1UZPA 1IOEL 1ADXA 4X8VL 2RA0L 2WPIE 3R05A 1WU1B 5E8DA 1PTHA 3HS7A 4RS0A 5JB8E 2KL7A 3KQBL 4O1ZA 2VH0B 4JZEL 2NPRA 2VWOL 2W86A 3BPSE 2XBWL 1LMJA 1EBVA 1PFXL 2MHPA 4LORA 4Z0KB 3KQEL 2VVCK 1F0RB 1MOXC 1HCGB 1U8CB 2UWPB 4TGFA 1UZJA 2J2UB 2MGRA 1NT0A 4BXWA 3LN0A 1IQHL 2MGPA 2Y7XB 1CVUA 1IQFL 4X8SL 3EGFA 4PH9A 3PGHA 2BO2A 1XKAL 1XDTR 2VJ3A 1JL9A 1SZBA 4JZFL 3F6UL 2VWLL 1LQDA 4MMZB 4ZAEB 4MMXB 3TBDA 3TK6B 2YGPA 1O5DL 4M11A 3ZYJB 2WPJE 1QFKL 5F19A 1ATDA 4Z6AL 3U73A 1WHFA 5COXA 1URKA 1XFEA 1PGEA 5JVZA 4COXA 1DIYA 3KQCL 3MDLA 1IQKL 2W3IB 2P3FN 2PHBB 1CCFA 3HS5A 3QCWA 1FAKL 3BT1A 2W2OE 2OYUP 1CVWL 2BOUA 1EPJA 1GK5A 3TZIA 2P26A 5JBAE 3N8XA 3NTGA 3CA7A 4D90A 1DX5I 2F9BL 3GISX 2CJIB 3KCGL 4XLWA 1Q4GA 1G2LB 2TGFA 4YT6L 2VVVL 1N1IA 4ZXXL 2GD4A 3Q7DA 4OTJA 3HS6A 2I9AA 1F0SB 2EI6B 3QMOA 2G00L 1KLJL 1LPZA 1OB1C 4RRWA 1HX2A 3LIWB 2P28B 1COUA 3N8WA 4BTUA 4BTIA 1G1QA 3V64C 3POYA 4X8UL 2KB9A 3F1SB 4O02B 1ZAQA 1L5GB 4E1GA 1FSBA 1V3XB 1FE2A 2XC5L 3GCXE 2OYEP 1YGCL 4XBMA 1HAFA 4CUFA 4Y6DB 3N8YB 1JBUL 1DQBA 2P95L 2W2ME 4C16A 2JKHL 2BMGA 1NQLB 2UWLB 1HJ7A 4NG9L 4BXSA 1IJQA 1BF9A 3C9AC 1FF7A 2Y80B 5JVYA 2I9BA 2FD6A 1G2MB 3LC5B 3CS7L 1IQNL 1HZ8A 1IQEL 2W26B 4YZUB 1IQJL 4D0FA 1RFNB 3NJPC 1IQIL 3M37L 1EMOA 5CKNA 5IKVA 3RR3A 5I46L 2BOKL 1DVAL 1NPEB 2ADXA 1U67A 2WFTA 2H9EL 1HAEA 2BQ7A 1B9WA 2W2NE 1IGZA 3FCSB 2XC4L 4ZHAB 4NGAL 4CSYA 2WG4B 4MMYB 2Y5HL 1J9CL 6COXA 1ATAA 1P0SL 2W2PE 3LTGD 3ENSA 4XL1A 2RNLA 4AQTA 2K2SB 2EI7B 1YUGA 2BOXA 2VWNL 3FBYA 1EQGA 3SOQA 4Y71B 3K9XA 3V65B 2M74A 1APQA 1CCVA 1XKBA 4OTYA 1FJSL 4NA9L 3LTFB 2BQWA 3SOVA 5K0HB 3HPTA 1EPIA 3CFWA 2P3FL 4X8TL 1M1XB 3U7UG 1W7XL 3OLUA 1KLIL 3M36L 1UZKA 1EPHA 5JBCE 1UZQA 2K2TA 4JYVL 2WYGB 5L30L 5CISA 1L3YA 4ZH8B 1FFMA 3HO5A 2Q1JB 2J4IB 4LMFA 3KK6A 3CENL 2W2QE 2PUQL 1EMNA 3TK5B 2P94L 3HO4A 2P16L 3KRKA 2WPHE 1CEJA 4FM5A 2J34B 1P9JA 1K36A 4RRZA 3LAQA 1IGXA 1KIGL 2EI8B 3N8WB 1CQEA 1G1RA 3N8VA 4Z0LA 4JZDL 3P5BL 2VVUL 1EAIC 1K37A 3NTBA 2WFXB 2YGOA 4BTTA 1NFYB 3N8YA 3Q3KB 1EGFA 1NZIA 2FLBL 4ZXYL 1APOA 5JW1A 3KQDL 1LPKA 2Y5FL 1Z6CA 1HREA 2AYLA 4RUTA 3SOBB 2DDUA 3MQEA 4G1MB 3H5CB 2XBYL 1LPGA 2FLGA 4CUDA 3ELAL 3ASIA 3OLTA 1ATBA 2XBVL 5CKMA 1PXXA 2J94B 3IJEB 1CX2A 2W3KB 1DDXA 1YUKB 1HRFA 1MQ5L 2P93L 1HT5A 1TOZA 3TH3L 1PRHA 2UWOB 2Y82B 2B7DL 1KSNB 3NT1A 2WPME 4A7IA 1N7DA 2FLRL 4ISIL 3FFGL 5JB9E 1WHEA 1A3PA 3BT2A 1NFUB 3LC3B 1G1SA 1F7EA 4ISHL 1IQGL 2XBXL 1JV2B 3LN1A 4Y7BB 3SW2A 5IKQA 1Z6EL 2Y81B 4M10A 5EGMB 1NFWB 5CKQA 1W8BL 4Y76B 3QH0A 5L2YL 4JYUL 1IQLL 4Y79B 4D0EA
chains in the Genus database with same CATH superfamily
1NFXB 4Y7AB 2RHPA 1IP0A 1F7MA 1EQHA 4RRYA 2FZZL 1MQ6L 5KIRA 2VH6B 2WYJB 5JBBE 2BZ6L 3GCWE 1TLEA 4BDWA 2BQ6A 3DEMA 1TPGA 2Y7ZB 5F1AA 2D1JB 3HO3A 5IKRA 4BDXA 2PR3B 2XC0L 3KL6B 1IOXA 1X7AL 3N8ZA 2VRSA 3TGFA 2J95B 5L2ZL 1HT8A 5FDQA 1AUTL 1G1TA 1EZQB 2BOHA 3IITB 4CUEA 5KN5C 1KLOA 4RRXA 3ZYGA 5IKTA 2J38B 1I0UA 2Y5GL 1YUFA 2KV4A 2VWMK 2Y38A 4YT7L 2WPKE 3ZYIB 2BSFA 1YO8A 1FAXL 2WG3C 2P3TA 1IQML 1IVOC 1ATEA 1EPGA 2P3UA 2WPLE 1C5MF 1UZPA 1IOEL 1ADXA 4X8VL 2RA0L 2WPIE 3R05A 1WU1B 5E8DA 1PTHA 3HS7A 4RS0A 5JB8E 3KQBL 2KL7A 4O1ZA 2VH0B 4JZEL 2NPRA 4GU3A 2VWOL 2W86A 3BPSE 3S6XA 2XBWL 2HOXA 1LMJA 1EBVA 1PFXL 2MHPA 4LORA 4Z0KB 3KQEL 2VVCK 1F0RB 1MOXC 1HCGB 1U8CB 2UWPB 4TGFA 1UZJA 2J2UB 2MGRA 1NT0A 4BXWA 3LN0A 1IQHL 2MGPA 2Y7XB 1CVUA 1IQFL 4X8SL 3EGFA 4PH9A 3PGHA 2BO2A 1XKAL 1XDTR 2VJ3A 1JL9A 1SZBA 4JZFL 3F6UL 2VWLL 1LQDA 4MMZB 4ZAEB 4MMXB 3TBDA 3TK6B 2YGPA 1O5DL 4M11A 3ZYJB 2WPJE 1QFKL 5F19A 1ATDA 4Z6AL 3U73A 1WHFA 5COXA 1URKA 1XFEA 1PGEA 5JVZA 4COXA 1DIYA 3KQCL 3MDLA 1IQKL 2W3IB 2P3FN 2KNIA 2PHBB 1CCFA 3HS5A 3QCWA 1FAKL 3BT1A 2W2OE 2OYUP 1CVWL 2BOUA 1EPJA 1GK5A 3TZIA 2P26A 5JBAE 3N8XA 3NTGA 3CA7A 4D90A 1DX5I 2F9BL 3GISX 2CJIB 3KCGL 4XLWA 1V1HA 1Q4GA 2JJLA 1G2LB 2TGFA 4YT6L 2VVVL 1N1IA 4ZXXL 2GD4A 3Q7DA 4OTJA 3HS6A 2I9AA 1F0SB 2EI6B 3QMOA 2G00L 1KLJL 1LPZA 1OB1C 4RRWA 1HX2A 3LIWB 2BT8A 2P28B 1COUA 3N8WA 4BTUA 4BTIA 1G1QA 3V64C 3POYA 4X8UL 2KB9A 3F1SB 4O02B 1ZAQA 1L5GB 4E1GA 1FSBA 1V3XB 1FE2A 2XC5L 3GCXE 2OYEP 1YGCL 4XBMA 1HAFA 4CUFA 4Y6DB 3N8YB 1JBUL 1DQBA 2P95L 2W2ME 4C16A 2JKHL 2BMGA 1NQLB 2UWLB 1HJ7A 4NG9L 4BXSA 1IJQA 1BF9A 3C9AC 1FF7A 2Y80B 5JVYA 2I9BA 2FD6A 1G2MB 3LC5B 3CS7L 1IQNL 1HZ8A 1IQEL 2W26B 4YZUB 1IQJL 4D0FA 1RFNB 3NJPC 1IQIL 3M37L 1EMOA 5CKNA 1V1IA 5IKVA 3RR3A 5I46L 2BOKL 1DVAL 1NPEB 2ADXA 1U67A 2WFTA 2H9EL 1HAEA 2BQ7A 1B9WA 2W2NE 1IGZA 3FCSB 2XC4L 4ZHAB 4NGAL 1KKEA 4CSYA 2WG4B 4MMYB 2Y5HL 1J9CL 6COXA 1ATAA 1P0SL 2W2PE 3LTGD 3ENSA 4XL1A 4A94C 2RNLA 4AQTA 2K2SB 2EI7B 1YUGA 2BOXA 2VWNL 3FBYA 1EQGA 3SOQA 2WZPP 4Y71B 3K9XA 3V65B 2M74A 1APQA 1CCVA 1XKBA 4OTYA 1FJSL 4NA9L 3LTFB 2BQWA 3SOVA 5K0HB 3HPTA 1EPIA 3CFWA 2YGQA 2P3FL 4X8TL 1M1XB 3U7UG 1W7XL 3OLUA 1KLIL 3M36L 1UZKA 1EPHA 4GU4A 5JBCE 1UZQA 2K2TA 4JYVL 2WYGB 5L30L 5CISA 1QIUA 1L3YA 4ZH8B 1FFMA 3HO5A 2Q1JB 2J4IB 4LMFA 3KK6A 3CENL 2W2QE 2PUQL 1EMNA 2HORA 3TK5B 2P94L 3HO4A 2P16L 3KRKA 2WPHE 1CEJA 4FM5A 1LMMA 2J34B 1P9JA 1K36A 4RRZA 3LAQA 1IGXA 1KIGL 2EI8B 3N8WB 1CQEA 1G1RA 3N8VA 4Z0LA 4JZDL 3P5BL 2VVUL 1EAIC 1K37A 3NTBA 2WFXB 2YGOA 4BTTA 1NFYB 3N8YA 3Q3KB 1EGFA 1NZIA 2FLBL 4ZXYL 1APOA 5JW1A 3KQDL 1LPKA 2Y5FL 1Z6CA 1HREA 2AYLA 4RUTA 3SOBB 2DDUA 3MQEA 4G1MB 3H5CB 2XBYL 1LPGA 2FLGA 4CUDA 3ELAL 3ASIA 3OLTA 1ATBA 2XBVL 5CKMA 1PXXA 2J94B 3IJEB 1CX2A 2W3KB 1DDXA 1YUKB 1HRFA 1MQ5L 2BT7A 2P93L 1HT5A 1TOZA 3TH3L 1PRHA 2UWOB 2Y82B 2B7DL 1KSNB 2H9EC 3NT1A 2WPME 4A7IA 1N7DA 2FLRL 4ISIL 3FFGL 5JB9E 1WHEA 1A3PA 3BT2A 1NFUB 3LC3B 1G1SA 1F7EA 4ISHL 1IQGL 2XBXL 1JV2B 3LN1A 4Y7BB 3SW2A 5IKQA 1Z6EL 2Y81B 4M10A 5EGMB 1NFWB 5CKQA 1W8BL 4Y76B 3QH0A 5L2YL 4JYUL 1IQLL 4Y79B 4D0EA 1LK9A
chains in the Genus database with same CATH topology
1NFXB 4Y7AB 2RHPA 1IP0A 1F7MA 1EQHA 4RRYA 2FZZL 1MQ6L 5KIRA 2VH6B 2WYJB 5JBBE 2BZ6L 3GCWE 1TLEA 4BDWA 2BQ6A 3DEMA 1TPGA 2Y7ZB 5F1AA 2D1JB 3HO3A 5IKRA 4BDXA 2PR3B 2XC0L 3KL6B 1IOXA 1X7AL 3N8ZA 3TGFA 2J95B 5L2ZL 1HT8A 5FDQA 1AUTL 1G1TA 1EZQB 2BOHA 3IITB 4CUEA 5KN5C 1KLOA 4RRXA 3ZYGA 5IKTA 2J38B 1I0UA 2Y5GL 1YUFA 2KV4A 2VWMK 2Y38A 4YT7L 2WPKE 3ZYIB 1YO8A 1FAXL 2WG3C 2P3TA 1IQML 1IVOC 1ATEA 1EPGA 2P3UA 2WPLE 1C5MF 1UZPA 1IOEL 1ADXA 4X8VL 2RA0L 2WPIE 3R05A 1WU1B 5E8DA 1PTHA 3HS7A 4RS0A 5JB8E 2KL7A 3KQBL 4O1ZA 2VH0B 4JZEL 2NPRA 2VWOL 2W86A 3BPSE 3S6XA 2XBWL 1LMJA 1EBVA 1PFXL 2MHPA 4LORA 4Z0KB 3KQEL 2VVCK 1F0RB 1MOXC 1HCGB 1U8CB 2UWPB 4TGFA 1UZJA 2J2UB 2MGRA 1NT0A 4BXWA 3LN0A 1IQHL 2MGPA 2Y7XB 1CVUA 1IQFL 4X8SL 3EGFA 4PH9A 3PGHA 2BO2A 1XKAL 1XDTR 2VJ3A 1JL9A 1SZBA 4JZFL 3F6UL 2VWLL 1LQDA 4MMZB 4ZAEB 4MMXB 3TBDA 3TK6B 2YGPA 1O5DL 4M11A 3ZYJB 2WPJE 1QFKL 5F19A 1ATDA 4Z6AL 3U73A 1WHFA 5COXA 1URKA 1XFEA 1PGEA 5JVZA 4COXA 1DIYA 3KQCL 3MDLA 1IQKL 2W3IB 2P3FN 2KNIA 2PHBB 1CCFA 3HS5A 3QCWA 1FAKL 3BT1A 2W2OE 2OYUP 1CVWL 2BOUA 1EPJA 1GK5A 3TZIA 2P26A 5JBAE 3N8XA 3NTGA 3CA7A 4D90A 1DX5I 2F9BL 3GISX 2CJIB 3KCGL 4XLWA 1Q4GA 1G2LB 2TGFA 4YT6L 2VVVL 1N1IA 4ZXXL 2GD4A 3Q7DA 4OTJA 3HS6A 2I9AA 1F0SB 2EI6B 3QMOA 2G00L 1KLJL 1LPZA 1OB1C 4RRWA 1HX2A 3LIWB 2P28B 1COUA 3N8WA 4BTUA 4BTIA 1G1QA 3V64C 3POYA 4X8UL 2KB9A 3F1SB 4O02B 1ZAQA 1L5GB 4E1GA 1FSBA 1V3XB 1FE2A 2XC5L 3GCXE 2OYEP 1YGCL 4XBMA 1HAFA 4CUFA 4Y6DB 3N8YB 1JBUL 1DQBA 2P95L 2W2ME 4C16A 2JKHL 2BMGA 1NQLB 2UWLB 1HJ7A 4NG9L 4BXSA 1IJQA 1BF9A 3C9AC 1FF7A 2Y80B 5JVYA 2I9BA 2FD6A 1G2MB 3LC5B 3CS7L 1IQNL 1HZ8A 1IQEL 2W26B 4YZUB 1IQJL 4D0FA 1RFNB 3NJPC 1IQIL 3M37L 1EMOA 5CKNA 5IKVA 3RR3A 5I46L 2BOKL 1DVAL 1NPEB 2ADXA 1U67A 2WFTA 2H9EL 1HAEA 2BQ7A 1B9WA 2W2NE 1IGZA 3FCSB 2XC4L 4ZHAB 4NGAL 4CSYA 2WG4B 4MMYB 2Y5HL 1J9CL 6COXA 1ATAA 1P0SL 2W2PE 3LTGD 3ENSA 4XL1A 4A94C 2RNLA 4AQTA 2K2SB 2EI7B 1YUGA 2BOXA 2VWNL 3FBYA 1EQGA 3SOQA 2WZPP 4Y71B 3K9XA 3V65B 2M74A 1APQA 1CCVA 1XKBA 4OTYA 1FJSL 4NA9L 3LTFB 2BQWA 3SOVA 5K0HB 3HPTA 1EPIA 3CFWA 2YGQA 2P3FL 4X8TL 1M1XB 3U7UG 1W7XL 3OLUA 1KLIL 3M36L 1UZKA 1EPHA 5JBCE 1UZQA 2K2TA 4JYVL 2WYGB 5L30L 5CISA 1L3YA 4ZH8B 1FFMA 3HO5A 2Q1JB 2J4IB 4LMFA 3KK6A 3CENL 2W2QE 2PUQL 1EMNA 3TK5B 2P94L 3HO4A 2P16L 3KRKA 2WPHE 1CEJA 4FM5A 1LMMA 2J34B 1P9JA 1K36A 4RRZA 3LAQA 1IGXA 1KIGL 2EI8B 3N8WB 1CQEA 1G1RA 3N8VA 4Z0LA 4JZDL 3P5BL 2VVUL 1EAIC 1K37A 3NTBA 2WFXB 2YGOA 4BTTA 1NFYB 3N8YA 3Q3KB 1EGFA 1NZIA 2FLBL 4ZXYL 1APOA 5JW1A 3KQDL 1LPKA 2Y5FL 1Z6CA 1HREA 2AYLA 4RUTA 3SOBB 2DDUA 3MQEA 4G1MB 3H5CB 2XBYL 1LPGA 2FLGA 4CUDA 3ELAL 3ASIA 3OLTA 1ATBA 2XBVL 5CKMA 1PXXA 2J94B 3IJEB 1CX2A 2W3KB 1DDXA 1YUKB 1HRFA 1MQ5L 2P93L 1HT5A 1TOZA 3TH3L 1PRHA 2UWOB 2Y82B 2B7DL 1KSNB 2H9EC 3NT1A 2WPME 4A7IA 1N7DA 2FLRL 4ISIL 3FFGL 5JB9E 1WHEA 1A3PA 3BT2A 1NFUB 3LC3B 1G1SA 1F7EA 4ISHL 1IQGL 2XBXL 1JV2B 3LN1A 4Y7BB 3SW2A 5IKQA 1Z6EL 2Y81B 4M10A 5EGMB 1NFWB 5CKQA 1W8BL 4Y76B 3QH0A 5L2YL 4JYUL 1IQLL 4Y79B 4D0EA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1NFX B;  4Y7A B;  2RHP A;  1IP0 A;  1F7M A;  1EQH A;  4RRY A;  2FZZ L;  1MQ6 L;  5KIR A;  2VH6 B;  2WYJ B;  5JBB E;  2BZ6 L;  3GCW E;  1TLE A;  4BDW A;  2BQ6 A;  3DEM A;  1TPG A;  2Y7Z B;  5F1A A;  2D1J B;  3HO3 A;  5IKR A;  4BDX A;  2PR3 B;  2XC0 L;  3KL6 B;  1IOX A;  1X7A L;  3N8Z A;  3TGF A;  2J95 B;  5L2Z L;  1HT8 A;  5FDQ A;  1AUT L;  1G1T A;  1EZQ B;  2BOH A;  3IIT B;  4CUE A;  5KN5 C;  1KLO A;  4RRX A;  3ZYG A;  5IKT A;  2J38 B;  1I0U A;  2Y5G L;  1YUF A;  2KV4 A;  2VWM K;  2Y38 A;  4YT7 L;  2WPK E;  3ZYI B;  1YO8 A;  1FAX L;  2WG3 C;  2P3T A;  1IQM L;  1IVO C;  1ATE A;  1EPG A;  2P3U A;  2WPL E;  1C5M F;  1UZP A;  1IOE L;  1ADX A;  4X8V L;  2RA0 L;  2WPI E;  3R05 A;  1WU1 B;  5E8D A;  1PTH A;  3HS7 A;  4RS0 A;  5JB8 E;  2KL7 A;  3KQB L;  4O1Z A;  2VH0 B;  4JZE L;  2NPR A;  2VWO L;  2W86 A;  3BPS E;  2XBW L;  1LMJ A;  1EBV A;  1PFX L;  2MHP A;  4LOR A;  4Z0K B;  3KQE L;  2VVC K;  1F0R B;  1MOX C;  1HCG B;  1U8C B;  2UWP B;  4TGF A;  1UZJ A;  2J2U B;  2MGR A;  1NT0 A;  4BXW A;  3LN0 A;  1IQH L;  2MGP A;  2Y7X B;  1CVU A;  1IQF L;  4X8S L;  3EGF A;  4PH9 A;  3PGH A;  2BO2 A;  1XKA L;  1XDT R;  2VJ3 A;  1JL9 A;  1SZB A;  4JZF L;  3F6U L;  2VWL L;  1LQD A;  4MMZ B;  4ZAE B;  4MMX B;  3TBD A;  3TK6 B;  2YGP A;  1O5D L;  4M11 A;  3ZYJ B;  2WPJ E;  1QFK L;  5F19 A;  1ATD A;  4Z6A L;  3U73 A;  1WHF A;  5COX A;  1URK A;  1XFE A;  1PGE A;  5JVZ A;  4COX A;  1DIY A;  3KQC L;  3MDL A;  1IQK L;  2W3I B;  2P3F N;  2PHB B;  1CCF A;  3HS5 A;  3QCW A;  1FAK L;  3BT1 A;  2W2O E;  2OYU P;  1CVW L;  2BOU A;  1EPJ A;  1GK5 A;  3TZI A;  2P26 A;  5JBA E;  3N8X A;  3NTG A;  3CA7 A;  4D90 A;  1DX5 I;  2F9B L;  3GIS X;  2CJI B;  3KCG L;  4XLW A;  1Q4G A;  1G2L B;  2TGF A;  4YT6 L;  2VVV L;  1N1I A;  4ZXX L;  2GD4 A;  3Q7D A;  4OTJ A;  3HS6 A;  2I9A A;  1F0S B;  2EI6 B;  3QMO A;  2G00 L;  1KLJ L;  1LPZ A;  1OB1 C;  4RRW A;  1HX2 A;  3LIW B;  2P28 B;  1COU A;  3N8W A;  4BTU A;  4BTI A;  1G1Q A;  3V64 C;  3POY A;  4X8U L;  2KB9 A;  3F1S B;  4O02 B;  1ZAQ A;  1L5G B;  4E1G A;  1FSB A;  1V3X B;  1FE2 A;  2XC5 L;  3GCX E;  2OYE P;  1YGC L;  4XBM A;  1HAF A;  4CUF A;  4Y6D B;  3N8Y B;  1JBU L;  1DQB A;  2P95 L;  2W2M E;  4C16 A;  2JKH L;  2BMG A;  1NQL B;  2UWL B;  1HJ7 A;  4NG9 L;  4BXS A;  1IJQ A;  1BF9 A;  3C9A C;  1FF7 A;  2Y80 B;  5JVY A;  2I9B A;  2FD6 A;  1G2M B;  3LC5 B;  3CS7 L;  1IQN L;  1HZ8 A;  1IQE L;  2W26 B;  4YZU B;  1IQJ L;  4D0F A;  1RFN B;  3NJP C;  1IQI L;  3M37 L;  1EMO A;  5CKN A;  5IKV A;  3RR3 A;  5I46 L;  2BOK L;  1DVA L;  1NPE B;  2ADX A;  1U67 A;  2WFT A;  2H9E L;  1HAE A;  2BQ7 A;  1B9W A;  2W2N E;  1IGZ A;  3FCS B;  2XC4 L;  4ZHA B;  4NGA L;  4CSY A;  2WG4 B;  4MMY B;  2Y5H L;  1J9C L;  6COX A;  1ATA A;  1P0S L;  2W2P E;  3LTG D;  3ENS A;  4XL1 A;  2RNL A;  4AQT A;  2K2S B;  2EI7 B;  1YUG A;  2BOX A;  2VWN L;  3FBY A;  1EQG A;  3SOQ A;  4Y71 B;  3K9X A;  3V65 B;  2M74 A;  1APQ A;  1CCV A;  1XKB A;  4OTY A;  1FJS L;  4NA9 L;  3LTF B;  2BQW A;  3SOV A;  5K0H B;  3HPT A;  1EPI A;  3CFW A;  2P3F L;  4X8T L;  1M1X B;  3U7U G;  1W7X L;  3OLU A;  1KLI L;  3M36 L;  1UZK A;  1EPH A;  5JBC E;  1UZQ A;  2K2T A;  4JYV L;  2WYG B;  5L30 L;  5CIS A;  1L3Y A;  4ZH8 B;  1FFM A;  3HO5 A;  2Q1J B;  2J4I B;  4LMF A;  3KK6 A;  3CEN L;  2W2Q E;  2PUQ L;  1EMN A;  3TK5 B;  2P94 L;  3HO4 A;  2P16 L;  3KRK A;  2WPH E;  1CEJ A;  4FM5 A;  2J34 B;  1P9J A;  1K36 A;  4RRZ A;  3LAQ A;  1IGX A;  1KIG L;  2EI8 B;  3N8W B;  1CQE A;  1G1R A;  3N8V A;  4Z0L A;  4JZD L;  3P5B L;  2VVU L;  1EAI C;  1K37 A;  3NTB A;  2WFX B;  2YGO A;  4BTT A;  1NFY B;  3N8Y A;  3Q3K B;  1EGF A;  1NZI A;  2FLB L;  4ZXY L;  1APO A;  5JW1 A;  3KQD L;  1LPK A;  2Y5F L;  1Z6C A;  1HRE A;  2AYL A;  4RUT A;  3SOB B;  2DDU A;  3MQE A;  4G1M B;  3H5C B;  2XBY L;  1LPG A;  2FLG A;  4CUD A;  3ELA L;  3ASI A;  3OLT A;  1ATB A;  2XBV L;  5CKM A;  1PXX A;  2J94 B;  3IJE B;  1CX2 A;  2W3K B;  1DDX A;  1YUK B;  1HRF A;  1MQ5 L;  2P93 L;  1HT5 A;  1TOZ A;  3TH3 L;  1PRH A;  2UWO B;  2Y82 B;  2B7D L;  1KSN B;  3NT1 A;  2WPM E;  4A7I A;  1N7D A;  2FLR L;  4ISI L;  3FFG L;  5JB9 E;  1WHE A;  1A3P A;  3BT2 A;  1NFU B;  3LC3 B;  1G1S A;  1F7E A;  4ISH L;  1IQG L;  2XBX L;  1JV2 B;  3LN1 A;  4Y7B B;  3SW2 A;  5IKQ A;  1Z6E L;  2Y81 B;  4M10 A;  5EGM B;  1NFW B;  5CKQ A;  1W8B L;  4Y76 B;  3QH0 A;  5L2Y L;  4JYU L;  1IQL L;  4Y79 B;  4D0E A; 
#chains in the Genus database with same CATH topology
 1NFX B;  4Y7A B;  2RHP A;  1IP0 A;  1F7M A;  1EQH A;  4RRY A;  2FZZ L;  1MQ6 L;  5KIR A;  2VH6 B;  2WYJ B;  5JBB E;  2BZ6 L;  3GCW E;  1TLE A;  4BDW A;  2BQ6 A;  3DEM A;  1TPG A;  2Y7Z B;  5F1A A;  2D1J B;  3HO3 A;  5IKR A;  4BDX A;  2PR3 B;  2XC0 L;  3KL6 B;  1IOX A;  1X7A L;  3N8Z A;  2VRS A;  3TGF A;  2J95 B;  5L2Z L;  1HT8 A;  5FDQ A;  1AUT L;  1G1T A;  1EZQ B;  2BOH A;  3IIT B;  4CUE A;  5KN5 C;  1KLO A;  4RRX A;  3ZYG A;  5IKT A;  2J38 B;  1I0U A;  2Y5G L;  1YUF A;  2KV4 A;  2VWM K;  2Y38 A;  4YT7 L;  2WPK E;  3ZYI B;  2BSF A;  1YO8 A;  1FAX L;  2WG3 C;  2P3T A;  1IQM L;  1IVO C;  1ATE A;  1EPG A;  2P3U A;  2WPL E;  1C5M F;  1UZP A;  1IOE L;  1ADX A;  4X8V L;  2RA0 L;  2WPI E;  3R05 A;  1WU1 B;  5E8D A;  1PTH A;  3HS7 A;  4RS0 A;  5JB8 E;  3KQB L;  2KL7 A;  4O1Z A;  2VH0 B;  4JZE L;  2NPR A;  4GU3 A;  2VWO L;  2W86 A;  3BPS E;  3S6X A;  2XBW L;  2HOX A;  1LMJ A;  1EBV A;  1PFX L;  2MHP A;  4LOR A;  4Z0K B;  3KQE L;  2VVC K;  1F0R B;  1MOX C;  1HCG B;  1U8C B;  2UWP B;  4TGF A;  1UZJ A;  2J2U B;  2MGR A;  1NT0 A;  4BXW A;  3LN0 A;  1IQH L;  2MGP A;  2Y7X B;  1CVU A;  1IQF L;  4X8S L;  3EGF A;  4PH9 A;  3PGH A;  2BO2 A;  1XKA L;  1XDT R;  2VJ3 A;  1JL9 A;  1SZB A;  4JZF L;  3F6U L;  2VWL L;  1LQD A;  4MMZ B;  4ZAE B;  4MMX B;  3TBD A;  3TK6 B;  2YGP A;  1O5D L;  4M11 A;  3ZYJ B;  2WPJ E;  1QFK L;  5F19 A;  1ATD A;  4Z6A L;  3U73 A;  1WHF A;  5COX A;  1URK A;  1XFE A;  1PGE A;  5JVZ A;  4COX A;  1DIY A;  3KQC L;  3MDL A;  1IQK L;  2W3I B;  2P3F N;  2KNI A;  2PHB B;  1CCF A;  3HS5 A;  3QCW A;  1FAK L;  3BT1 A;  2W2O E;  2OYU P;  1CVW L;  2BOU A;  1EPJ A;  1GK5 A;  3TZI A;  2P26 A;  5JBA E;  3N8X A;  3NTG A;  3CA7 A;  4D90 A;  1DX5 I;  2F9B L;  3GIS X;  2CJI B;  3KCG L;  4XLW A;  1V1H A;  1Q4G A;  2JJL A;  1G2L B;  2TGF A;  4YT6 L;  2VVV L;  1N1I A;  4ZXX L;  2GD4 A;  3Q7D A;  4OTJ A;  3HS6 A;  2I9A A;  1F0S B;  2EI6 B;  3QMO A;  2G00 L;  1KLJ L;  1LPZ A;  1OB1 C;  4RRW A;  1HX2 A;  3LIW B;  2BT8 A;  2P28 B;  1COU A;  3N8W A;  4BTU A;  4BTI A;  1G1Q A;  3V64 C;  3POY A;  4X8U L;  2KB9 A;  3F1S B;  4O02 B;  1ZAQ A;  1L5G B;  4E1G A;  1FSB A;  1V3X B;  1FE2 A;  2XC5 L;  3GCX E;  2OYE P;  1YGC L;  4XBM A;  1HAF A;  4CUF A;  4Y6D B;  3N8Y B;  1JBU L;  1DQB A;  2P95 L;  2W2M E;  4C16 A;  2JKH L;  2BMG A;  1NQL B;  2UWL B;  1HJ7 A;  4NG9 L;  4BXS A;  1IJQ A;  1BF9 A;  3C9A C;  1FF7 A;  2Y80 B;  5JVY A;  2I9B A;  2FD6 A;  1G2M B;  3LC5 B;  3CS7 L;  1IQN L;  1HZ8 A;  1IQE L;  2W26 B;  4YZU B;  1IQJ L;  4D0F A;  1RFN B;  3NJP C;  1IQI L;  3M37 L;  1EMO A;  5CKN A;  1V1I A;  5IKV A;  3RR3 A;  5I46 L;  2BOK L;  1DVA L;  1NPE B;  2ADX A;  1U67 A;  2WFT A;  2H9E L;  1HAE A;  2BQ7 A;  1B9W A;  2W2N E;  1IGZ A;  3FCS B;  2XC4 L;  4ZHA B;  4NGA L;  1KKE A;  4CSY A;  2WG4 B;  4MMY B;  2Y5H L;  1J9C L;  6COX A;  1ATA A;  1P0S L;  2W2P E;  3LTG D;  3ENS A;  4XL1 A;  4A94 C;  2RNL A;  4AQT A;  2K2S B;  2EI7 B;  1YUG A;  2BOX A;  2VWN L;  3FBY A;  1EQG A;  3SOQ A;  2WZP P;  4Y71 B;  3K9X A;  3V65 B;  2M74 A;  1APQ A;  1CCV A;  1XKB A;  4OTY A;  1FJS L;  4NA9 L;  3LTF B;  2BQW A;  3SOV A;  5K0H B;  3HPT A;  1EPI A;  3CFW A;  2YGQ A;  2P3F L;  4X8T L;  1M1X B;  3U7U G;  1W7X L;  3OLU A;  1KLI L;  3M36 L;  1UZK A;  1EPH A;  4GU4 A;  5JBC E;  1UZQ A;  2K2T A;  4JYV L;  2WYG B;  5L30 L;  5CIS A;  1QIU A;  1L3Y A;  4ZH8 B;  1FFM A;  3HO5 A;  2Q1J B;  2J4I B;  4LMF A;  3KK6 A;  3CEN L;  2W2Q E;  2PUQ L;  1EMN A;  2HOR A;  3TK5 B;  2P94 L;  3HO4 A;  2P16 L;  3KRK A;  2WPH E;  1CEJ A;  4FM5 A;  1LMM A;  2J34 B;  1P9J A;  1K36 A;  4RRZ A;  3LAQ A;  1IGX A;  1KIG L;  2EI8 B;  3N8W B;  1CQE A;  1G1R A;  3N8V A;  4Z0L A;  4JZD L;  3P5B L;  2VVU L;  1EAI C;  1K37 A;  3NTB A;  2WFX B;  2YGO A;  4BTT A;  1NFY B;  3N8Y A;  3Q3K B;  1EGF A;  1NZI A;  2FLB L;  4ZXY L;  1APO A;  5JW1 A;  3KQD L;  1LPK A;  2Y5F L;  1Z6C A;  1HRE A;  2AYL A;  4RUT A;  3SOB B;  2DDU A;  3MQE A;  4G1M B;  3H5C B;  2XBY L;  1LPG A;  2FLG A;  4CUD A;  3ELA L;  3ASI A;  3OLT A;  1ATB A;  2XBV L;  5CKM A;  1PXX A;  2J94 B;  3IJE B;  1CX2 A;  2W3K B;  1DDX A;  1YUK B;  1HRF A;  1MQ5 L;  2BT7 A;  2P93 L;  1HT5 A;  1TOZ A;  3TH3 L;  1PRH A;  2UWO B;  2Y82 B;  2B7D L;  1KSN B;  2H9E C;  3NT1 A;  2WPM E;  4A7I A;  1N7D A;  2FLR L;  4ISI L;  3FFG L;  5JB9 E;  1WHE A;  1A3P A;  3BT2 A;  1NFU B;  3LC3 B;  1G1S A;  1F7E A;  4ISH L;  1IQG L;  2XBX L;  1JV2 B;  3LN1 A;  4Y7B B;  3SW2 A;  5IKQ A;  1Z6E L;  2Y81 B;  4M10 A;  5EGM B;  1NFW B;  5CKQ A;  1W8B L;  4Y76 B;  3QH0 A;  5L2Y L;  4JYU L;  1IQL L;  4Y79 B;  4D0E A;  1LK9 A; 
#chains in the Genus database with same CATH homology
 1NFX B;  4Y7A B;  2RHP A;  1IP0 A;  1F7M A;  1EQH A;  4RRY A;  2FZZ L;  1MQ6 L;  5KIR A;  2VH6 B;  2WYJ B;  5JBB E;  2BZ6 L;  3GCW E;  1TLE A;  4BDW A;  2BQ6 A;  3DEM A;  1TPG A;  2Y7Z B;  5F1A A;  2D1J B;  3HO3 A;  5IKR A;  4BDX A;  2PR3 B;  2XC0 L;  3KL6 B;  1IOX A;  1X7A L;  3N8Z A;  3TGF A;  2J95 B;  5L2Z L;  1HT8 A;  5FDQ A;  1AUT L;  1G1T A;  1EZQ B;  2BOH A;  3IIT B;  4CUE A;  5KN5 C;  1KLO A;  4RRX A;  3ZYG A;  5IKT A;  2J38 B;  1I0U A;  2Y5G L;  1YUF A;  2KV4 A;  2VWM K;  2Y38 A;  4YT7 L;  2WPK E;  3ZYI B;  1YO8 A;  1FAX L;  2WG3 C;  2P3T A;  1IQM L;  1IVO C;  1ATE A;  1EPG A;  2P3U A;  2WPL E;  1C5M F;  1UZP A;  1IOE L;  1ADX A;  4X8V L;  2RA0 L;  2WPI E;  3R05 A;  1WU1 B;  5E8D A;  1PTH A;  3HS7 A;  4RS0 A;  5JB8 E;  2KL7 A;  3KQB L;  4O1Z A;  2VH0 B;  4JZE L;  2NPR A;  2VWO L;  2W86 A;  3BPS E;  3S6X A;  2XBW L;  1LMJ A;  1EBV A;  1PFX L;  2MHP A;  4LOR A;  4Z0K B;  3KQE L;  2VVC K;  1F0R B;  1MOX C;  1HCG B;  1U8C B;  2UWP B;  4TGF A;  1UZJ A;  2J2U B;  2MGR A;  1NT0 A;  4BXW A;  3LN0 A;  1IQH L;  2MGP A;  2Y7X B;  1CVU A;  1IQF L;  4X8S L;  3EGF A;  4PH9 A;  3PGH A;  2BO2 A;  1XKA L;  1XDT R;  2VJ3 A;  1JL9 A;  1SZB A;  4JZF L;  3F6U L;  2VWL L;  1LQD A;  4MMZ B;  4ZAE B;  4MMX B;  3TBD A;  3TK6 B;  2YGP A;  1O5D L;  4M11 A;  3ZYJ B;  2WPJ E;  1QFK L;  5F19 A;  1ATD A;  4Z6A L;  3U73 A;  1WHF A;  5COX A;  1URK A;  1XFE A;  1PGE A;  5JVZ A;  4COX A;  1DIY A;  3KQC L;  3MDL A;  1IQK L;  2W3I B;  2P3F N;  2KNI A;  2PHB B;  1CCF A;  3HS5 A;  3QCW A;  1FAK L;  3BT1 A;  2W2O E;  2OYU P;  1CVW L;  2BOU A;  1EPJ A;  1GK5 A;  3TZI A;  2P26 A;  5JBA E;  3N8X A;  3NTG A;  3CA7 A;  4D90 A;  1DX5 I;  2F9B L;  3GIS X;  2CJI B;  3KCG L;  4XLW A;  1Q4G A;  1G2L B;  2TGF A;  4YT6 L;  2VVV L;  1N1I A;  4ZXX L;  2GD4 A;  3Q7D A;  4OTJ A;  3HS6 A;  2I9A A;  1F0S B;  2EI6 B;  3QMO A;  2G00 L;  1KLJ L;  1LPZ A;  1OB1 C;  4RRW A;  1HX2 A;  3LIW B;  2P28 B;  1COU A;  3N8W A;  4BTU A;  4BTI A;  1G1Q A;  3V64 C;  3POY A;  4X8U L;  2KB9 A;  3F1S B;  4O02 B;  1ZAQ A;  1L5G B;  4E1G A;  1FSB A;  1V3X B;  1FE2 A;  2XC5 L;  3GCX E;  2OYE P;  1YGC L;  4XBM A;  1HAF A;  4CUF A;  4Y6D B;  3N8Y B;  1JBU L;  1DQB A;  2P95 L;  2W2M E;  4C16 A;  2JKH L;  2BMG A;  1NQL B;  2UWL B;  1HJ7 A;  4NG9 L;  4BXS A;  1IJQ A;  1BF9 A;  3C9A C;  1FF7 A;  2Y80 B;  5JVY A;  2I9B A;  2FD6 A;  1G2M B;  3LC5 B;  3CS7 L;  1IQN L;  1HZ8 A;  1IQE L;  2W26 B;  4YZU B;  1IQJ L;  4D0F A;  1RFN B;  3NJP C;  1IQI L;  3M37 L;  1EMO A;  5CKN A;  5IKV A;  3RR3 A;  5I46 L;  2BOK L;  1DVA L;  1NPE B;  2ADX A;  1U67 A;  2WFT A;  2H9E L;  1HAE A;  2BQ7 A;  1B9W A;  2W2N E;  1IGZ A;  3FCS B;  2XC4 L;  4ZHA B;  4NGA L;  4CSY A;  2WG4 B;  4MMY B;  2Y5H L;  1J9C L;  6COX A;  1ATA A;  1P0S L;  2W2P E;  3LTG D;  3ENS A;  4XL1 A;  4A94 C;  2RNL A;  4AQT A;  2K2S B;  2EI7 B;  1YUG A;  2BOX A;  2VWN L;  3FBY A;  1EQG A;  3SOQ A;  2WZP P;  4Y71 B;  3K9X A;  3V65 B;  2M74 A;  1APQ A;  1CCV A;  1XKB A;  4OTY A;  1FJS L;  4NA9 L;  3LTF B;  2BQW A;  3SOV A;  5K0H B;  3HPT A;  1EPI A;  3CFW A;  2YGQ A;  2P3F L;  4X8T L;  1M1X B;  3U7U G;  1W7X L;  3OLU A;  1KLI L;  3M36 L;  1UZK A;  1EPH A;  5JBC E;  1UZQ A;  2K2T A;  4JYV L;  2WYG B;  5L30 L;  5CIS A;  1L3Y A;  4ZH8 B;  1FFM A;  3HO5 A;  2Q1J B;  2J4I B;  4LMF A;  3KK6 A;  3CEN L;  2W2Q E;  2PUQ L;  1EMN A;  3TK5 B;  2P94 L;  3HO4 A;  2P16 L;  3KRK A;  2WPH E;  1CEJ A;  4FM5 A;  1LMM A;  2J34 B;  1P9J A;  1K36 A;  4RRZ A;  3LAQ A;  1IGX A;  1KIG L;  2EI8 B;  3N8W B;  1CQE A;  1G1R A;  3N8V A;  4Z0L A;  4JZD L;  3P5B L;  2VVU L;  1EAI C;  1K37 A;  3NTB A;  2WFX B;  2YGO A;  4BTT A;  1NFY B;  3N8Y A;  3Q3K B;  1EGF A;  1NZI A;  2FLB L;  4ZXY L;  1APO A;  5JW1 A;  3KQD L;  1LPK A;  2Y5F L;  1Z6C A;  1HRE A;  2AYL A;  4RUT A;  3SOB B;  2DDU A;  3MQE A;  4G1M B;  3H5C B;  2XBY L;  1LPG A;  2FLG A;  4CUD A;  3ELA L;  3ASI A;  3OLT A;  1ATB A;  2XBV L;  5CKM A;  1PXX A;  2J94 B;  3IJE B;  1CX2 A;  2W3K B;  1DDX A;  1YUK B;  1HRF A;  1MQ5 L;  2P93 L;  1HT5 A;  1TOZ A;  3TH3 L;  1PRH A;  2UWO B;  2Y82 B;  2B7D L;  1KSN B;  2H9E C;  3NT1 A;  2WPM E;  4A7I A;  1N7D A;  2FLR L;  4ISI L;  3FFG L;  5JB9 E;  1WHE A;  1A3P A;  3BT2 A;  1NFU B;  3LC3 B;  1G1S A;  1F7E A;  4ISH L;  1IQG L;  2XBX L;  1JV2 B;  3LN1 A;  4Y7B B;  3SW2 A;  5IKQ A;  1Z6E L;  2Y81 B;  4M10 A;  5EGM B;  1NFW B;  5CKQ A;  1W8B L;  4Y76 B;  3QH0 A;  5L2Y L;  4JYU L;  1IQL L;  4Y79 B;  4D0E A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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