1PQFA

Glycine 24 to serine mutation of aspartate decarboxylase
Total Genus 35
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
35
sequence length
127
structure length
126
Chain Sequence
PRGSMIRTMLQGKLHRVKVTHADLHYESSCAIDQDFLDAAGILENEAIDIWNVTNGKRFSTYAIAAERGSRIISVNGAAAHASVGDIVIIASFVTMPDEEARTWRPNVAYFEGDNEMKRTAKAIPV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural constraints on protein self-processing in L-aspartate-alpha-decarboxylase
pubmed doi rcsb
molecule tags Lyase
source organism Escherichia coli
molecule keywords Aspartate 1-decarboxylase
total genus 35
structure length 126
sequence length 127
chains with identical sequence B
ec nomenclature ec 4.1.1.11: Aspartate 1-decarboxylase.
pdb deposition date 2003-06-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02261 Asp_decarbox Aspartate decarboxylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.40.20 Mainly Beta Beta Barrel Barwin-like endoglucanases Barwin-like endoglucanases 1pqfA00
4KLNA 2E2IA 2JIQA 1VC3B 1H0HA 2JIPA 1H5NA 3QQ8A 2NYAA 3CQZA 3QC8A 1DMRA 2R93A 2YU9A 1CR5A 1G8JA 1CZ4A 3GTGA 3TIWA 3GTKA 2WB1A 3GTOA 1FDOA 2DMRA 1R9TA 2NVYA 4AONB 1YLEA 5DYGA 4GA6A 1E32A 2R7ZA 4KO8A 1I50A 3GTPA 1PYUB 5DYIA 5FTJA 1SFOA 5B6CA 2NAPA 1KQGA 3TM7B 1Y5IA 5T5ID 5C1BA 1CZ5A 5GLFA 1KQFA 4CRYG 2EEOB 4D7ZB 2VUMA 1I3QA 4CRZA 1E61A 1PQFA 4KDLA 1DMSA 2JA5A 3GTQA 5T5MD 3ML1A 4CS0A 1E5VA 3IR5A 1R7RA 1Y1VA 1WLFA 1UHDA 3QQ7A 1G8KA 1K83A 2C45A 2V45A 1E60A 4AYBA 1OGYA 4GA5A 1TWFA 5FTKA 2JIOA 1AW8B 5C18A 1E18A 1S3SA 2VPWA 1PT1A 2VPXA 1PQHA 3GTJA 5FTNA 2WAQA 1TWGA 4AAYA 4DMRA 2R92A 2KI8A 4RV0A 1TWAA 2PMZA 1PT0A 3O5AA 3CF2A 3HU3A 2IV2X 4AZDA 3GTLA 3QWZA 2JA7A 1UHEA 1TWHA 1Y4ZA 2JIRA 1QCSA 5EPPA 2VPZA 3GTMA 1Y1WA 2E7ZA 4KODA 2B63A 1PYQA 1EU1A 1Q16A 1IW7D 2NVXA 3DMRA 2V3VA 1TWCA 2JA6A 1SIWA 3OUGA 4QIWA 5FTMA 1AA6A 3IR7A 1QDNA 3HU1A 4C2MA 2Y0SA 1TMOA 1FDIA 1PPYA 1PQEA 3H0GA 2E2HA 3FKIA 3HU2A 1R27A 3PLXB 4KDIA 1WCMA 2PJHB 2VPYA 5FTLA 4AOKB 2JIMA 3HKZA 3IR6A
chains in the Genus database with same CATH superfamily
3X2KA 1BW4A 4KLNA 2E2IA 2JIQA 1VC3B 3X2MA 1H0HA 2JIPA 1H5NA 3QQ8A 2NYAA 3CQZA 2A69D 3QC8A 1DMRA 2BH0A 1YNJD 2R93A 2YU9A 1CR5A 4NOHA 1G8JA 2CW0D 1CZ4A 3GTGA 3TIWA 3GTKA 2WB1A 3GTOA 2O5JD 1FDOA 2DMRA 2PICA 1R9TA 2NVYA 4AONB 1YLEA 5DYGA 4GA6A 1E32A 4JJOA 4KO8A 1I50A 2R7ZA 3GTPA 1PYUB 5DYIA 1WC2A 5FTJA 1N10A 2G5DA 1SFOA 5B6CA 2BE5D 2NAPA 1KQGA 4ENGA 3TM7B 1Y5IA 3M3GA 5T5ID 5C1BA 1CZ5A 2A6HD 5GLFA 1KQFA 3X2OA 1L8FA 4CRYG 2EEOB 4D7ZB 2VUMA 2A68D 1I3QA 4CRZA 1E61A 1PQFA 4AVRA 4KDLA 1DMSA 4ZM7A 2G6GA 3GTQA 2JA5A 5T5MD 3ML1A 3X2PA 5GM9A 4CS0A 1E5VA 3IR5A 1R7RA 1Y1VA 1WLFA 1UHDA 3QQ7A 1G8KA 3X2NA 2PNWA 1K83A 2ENGA 2C45A 2V45A 1E60A 1HD5A 4AYBA 1OGYA 4GA5A 1TWFA 2GAEA 5FTKA 2JIOA 1AW8B 5C18A 1E18A 1S3SA 2VPWA 1PT1A 2VPXA 1PQHA 3CZBA 3GTJA 5FTNA 2WAQA 2HCZX 1TWGA 2PJJA 3X2GA 4AAYA 3D30A 4DMRA 2R92A 2KQAA 2KI8A 4RV0A 1TWAA 4JP7A 2PMZA 3ENGA 4JCWA 1PT0A 3O5AA 3CF2A 3HU3A 2IV2X 4AZDA 1ZC1A 3GTLA 3QWZA 2JA7A 4FG4A 1UHEA 1TWHA 3SULA 1Y4ZA 2JIRA 1QCSA 5EPPA 2VPZA 3X2IA 3X2HA 3GTMA 2AE0X 4FERA 4FG2A 5GLXA 1Y1WA 2E7ZA 4KODA 2B63A 1PYQA 1EU1A 4L48A 1Q16A 1ZYRD 1SMYD 1IW7D 2NVXA 3DMRA 1BW3A 2V3VA 1TWCA 4JS7A 2JA6A 2YUJA 1SIWA 4JP6A 3OUGA 4QIWA 5FTMA 4FFTA 3IR7A 3X2JA 1AA6A 1QDNA 5GLYA 3HU1A 4C2MA 3SUKA 5H4UA 2A6ED 2Y0SA 1TMOA 1FDIA 1PPYA 1PQEA 3H0GA 2E2HA 3SUJA 3FKIA 3HU2A 3SUMA 1R27A 3X2LA 3PLXB 4KDIA 1OA9A 1WCMA 2PJHB 2VPYA 1OA7A 5FTLA 4AOKB 2JIMA 3HKZA 2PI8A 3IR6A 1YNND
chains in the Genus database with same CATH topology
4KLNA 2E2IA 2JIQA 1VC3B 1H0HA 2JIPA 1H5NA 3QQ8A 2NYAA 3CQZA 2A69D 3QC8A 1DMRA 1YNJD 2R93A 2YU9A 1CR5A 4NOHA 1G8JA 2CW0D 1CZ4A 3GTGA 3TIWA 3GTKA 2WB1A 3GTOA 2O5JD 1FDOA 2DMRA 2PICA 1R9TA 2NVYA 4AONB 1YLEA 5DYGA 4GA6A 1E32A 2R7ZA 4KO8A 1I50A 3GTPA 1PYUB 5DYIA 5FTJA 2G5DA 1SFOA 5B6CA 2BE5D 2NAPA 1KQGA 3TM7B 1Y5IA 5T5ID 5C1BA 1CZ5A 2A6HD 5GLFA 1KQFA 4CRYG 2EEOB 4D7ZB 2VUMA 2A68D 1I3QA 4CRZA 1E61A 1PQFA 4KDLA 1DMSA 2G6GA 3GTQA 2JA5A 5T5MD 3ML1A 4CS0A 1E5VA 3IR5A 1R7RA 1Y1VA 1WLFA 1UHDA 3QQ7A 1G8KA 1K83A 2PNWA 2C45A 2V45A 1E60A 4AYBA 1OGYA 4GA5A 1TWFA 2GAEA 5FTKA 2JIOA 1AW8B 5C18A 1E18A 1S3SA 2VPWA 1PT1A 2VPXA 1PQHA 3CZBA 3GTJA 5FTNA 2WAQA 1TWGA 2PJJA 4AAYA 4DMRA 2R92A 2KI8A 4RV0A 1TWAA 2PMZA 1PT0A 3O5AA 3CF2A 3HU3A 2IV2X 4AZDA 1ZC1A 3GTLA 3QWZA 2JA7A 1UHEA 1TWHA 1Y4ZA 2JIRA 1QCSA 5EPPA 2VPZA 3GTMA 2AE0X 1Y1WA 2E7ZA 4KODA 2B63A 1PYQA 1EU1A 1Q16A 1ZYRD 1SMYD 1IW7D 2NVXA 3DMRA 2V3VA 1TWCA 2JA6A 2YUJA 1SIWA 3OUGA 4QIWA 5FTMA 1AA6A 3IR7A 1QDNA 3HU1A 4C2MA 2A6ED 2Y0SA 1TMOA 1FDIA 1PPYA 1PQEA 3H0GA 2E2HA 3FKIA 3HU2A 1R27A 3PLXB 4KDIA 1WCMA 2PJHB 2VPYA 5FTLA 4AOKB 2JIMA 3HKZA 2PI8A 3IR6A 1YNND
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4KLN A;  2E2I A;  2JIQ A;  1VC3 B;  1H0H A;  2JIP A;  1H5N A;  3QQ8 A;  2NYA A;  3CQZ A;  3QC8 A;  1DMR A;  2R93 A;  2YU9 A;  1CR5 A;  1G8J A;  1CZ4 A;  3GTG A;  3TIW A;  3GTK A;  2WB1 A;  3GTO A;  1FDO A;  2DMR A;  1R9T A;  2NVY A;  4AON B;  1YLE A;  5DYG A;  4GA6 A;  1E32 A;  2R7Z A;  4KO8 A;  1I50 A;  3GTP A;  1PYU B;  5DYI A;  5FTJ A;  1SFO A;  5B6C A;  2NAP A;  1KQG A;  3TM7 B;  1Y5I A;  5T5I D;  5C1B A;  1CZ5 A;  5GLF A;  1KQF A;  4CRY G;  2EEO B;  4D7Z B;  2VUM A;  1I3Q A;  4CRZ A;  1E61 A;  1PQF A;  4KDL A;  1DMS A;  2JA5 A;  3GTQ A;  5T5M D;  3ML1 A;  4CS0 A;  1E5V A;  3IR5 A;  1R7R A;  1Y1V A;  1WLF A;  1UHD A;  3QQ7 A;  1G8K A;  1K83 A;  2C45 A;  2V45 A;  1E60 A;  4AYB A;  1OGY A;  4GA5 A;  1TWF A;  5FTK A;  2JIO A;  1AW8 B;  5C18 A;  1E18 A;  1S3S A;  2VPW A;  1PT1 A;  2VPX A;  1PQH A;  3GTJ A;  5FTN A;  2WAQ A;  1TWG A;  4AAY A;  4DMR A;  2R92 A;  2KI8 A;  4RV0 A;  1TWA A;  2PMZ A;  1PT0 A;  3O5A A;  3CF2 A;  3HU3 A;  2IV2 X;  4AZD A;  3GTL A;  3QWZ A;  2JA7 A;  1UHE A;  1TWH A;  1Y4Z A;  2JIR A;  1QCS A;  5EPP A;  2VPZ A;  3GTM A;  1Y1W A;  2E7Z A;  4KOD A;  2B63 A;  1PYQ A;  1EU1 A;  1Q16 A;  1IW7 D;  2NVX A;  3DMR A;  2V3V A;  1TWC A;  2JA6 A;  1SIW A;  3OUG A;  4QIW A;  5FTM A;  1AA6 A;  3IR7 A;  1QDN A;  3HU1 A;  4C2M A;  2Y0S A;  1TMO A;  1FDI A;  1PPY A;  1PQE A;  3H0G A;  2E2H A;  3FKI A;  3HU2 A;  1R27 A;  3PLX B;  4KDI A;  1WCM A;  2PJH B;  2VPY A;  5FTL A;  4AOK B;  2JIM A;  3HKZ A;  3IR6 A; 
#chains in the Genus database with same CATH topology
 3X2K A;  1BW4 A;  4KLN A;  2E2I A;  2JIQ A;  1VC3 B;  3X2M A;  1H0H A;  2JIP A;  1H5N A;  3QQ8 A;  2NYA A;  3CQZ A;  2A69 D;  3QC8 A;  1DMR A;  2BH0 A;  1YNJ D;  2R93 A;  2YU9 A;  1CR5 A;  4NOH A;  1G8J A;  2CW0 D;  1CZ4 A;  3GTG A;  3TIW A;  3GTK A;  2WB1 A;  3GTO A;  2O5J D;  1FDO A;  2DMR A;  2PIC A;  1R9T A;  2NVY A;  4AON B;  1YLE A;  5DYG A;  4GA6 A;  1E32 A;  4JJO A;  4KO8 A;  1I50 A;  2R7Z A;  3GTP A;  1PYU B;  5DYI A;  1WC2 A;  5FTJ A;  1N10 A;  2G5D A;  1SFO A;  5B6C A;  2BE5 D;  2NAP A;  1KQG A;  4ENG A;  3TM7 B;  1Y5I A;  3M3G A;  5T5I D;  5C1B A;  1CZ5 A;  2A6H D;  5GLF A;  1KQF A;  3X2O A;  1L8F A;  4CRY G;  2EEO B;  4D7Z B;  2VUM A;  2A68 D;  1I3Q A;  4CRZ A;  1E61 A;  1PQF A;  4AVR A;  4KDL A;  1DMS A;  4ZM7 A;  2G6G A;  3GTQ A;  2JA5 A;  5T5M D;  3ML1 A;  3X2P A;  5GM9 A;  4CS0 A;  1E5V A;  3IR5 A;  1R7R A;  1Y1V A;  1WLF A;  1UHD A;  3QQ7 A;  1G8K A;  3X2N A;  2PNW A;  1K83 A;  2ENG A;  2C45 A;  2V45 A;  1E60 A;  1HD5 A;  4AYB A;  1OGY A;  4GA5 A;  1TWF A;  2GAE A;  5FTK A;  2JIO A;  1AW8 B;  5C18 A;  1E18 A;  1S3S A;  2VPW A;  1PT1 A;  2VPX A;  1PQH A;  3CZB A;  3GTJ A;  5FTN A;  2WAQ A;  2HCZ X;  1TWG A;  2PJJ A;  3X2G A;  4AAY A;  3D30 A;  4DMR A;  2R92 A;  2KQA A;  2KI8 A;  4RV0 A;  1TWA A;  4JP7 A;  2PMZ A;  3ENG A;  4JCW A;  1PT0 A;  3O5A A;  3CF2 A;  3HU3 A;  2IV2 X;  4AZD A;  1ZC1 A;  3GTL A;  3QWZ A;  2JA7 A;  4FG4 A;  1UHE A;  1TWH A;  3SUL A;  1Y4Z A;  2JIR A;  1QCS A;  5EPP A;  2VPZ A;  3X2I A;  3X2H A;  3GTM A;  2AE0 X;  4FER A;  4FG2 A;  5GLX A;  1Y1W A;  2E7Z A;  4KOD A;  2B63 A;  1PYQ A;  1EU1 A;  4L48 A;  1Q16 A;  1ZYR D;  1SMY D;  1IW7 D;  2NVX A;  3DMR A;  1BW3 A;  2V3V A;  1TWC A;  4JS7 A;  2JA6 A;  2YUJ A;  1SIW A;  4JP6 A;  3OUG A;  4QIW A;  5FTM A;  4FFT A;  3IR7 A;  3X2J A;  1AA6 A;  1QDN A;  5GLY A;  3HU1 A;  4C2M A;  3SUK A;  5H4U A;  2A6E D;  2Y0S A;  1TMO A;  1FDI A;  1PPY A;  1PQE A;  3H0G A;  2E2H A;  3SUJ A;  3FKI A;  3HU2 A;  3SUM A;  1R27 A;  3X2L A;  3PLX B;  4KDI A;  1OA9 A;  1WCM A;  2PJH B;  2VPY A;  1OA7 A;  5FTL A;  4AOK B;  2JIM A;  3HKZ A;  2PI8 A;  3IR6 A;  1YNN D; 
#chains in the Genus database with same CATH homology
 4KLN A;  2E2I A;  2JIQ A;  1VC3 B;  1H0H A;  2JIP A;  1H5N A;  3QQ8 A;  2NYA A;  3CQZ A;  2A69 D;  3QC8 A;  1DMR A;  1YNJ D;  2R93 A;  2YU9 A;  1CR5 A;  4NOH A;  1G8J A;  2CW0 D;  1CZ4 A;  3GTG A;  3TIW A;  3GTK A;  2WB1 A;  3GTO A;  2O5J D;  1FDO A;  2DMR A;  2PIC A;  1R9T A;  2NVY A;  4AON B;  1YLE A;  5DYG A;  4GA6 A;  1E32 A;  2R7Z A;  4KO8 A;  1I50 A;  3GTP A;  1PYU B;  5DYI A;  5FTJ A;  2G5D A;  1SFO A;  5B6C A;  2BE5 D;  2NAP A;  1KQG A;  3TM7 B;  1Y5I A;  5T5I D;  5C1B A;  1CZ5 A;  2A6H D;  5GLF A;  1KQF A;  4CRY G;  2EEO B;  4D7Z B;  2VUM A;  2A68 D;  1I3Q A;  4CRZ A;  1E61 A;  1PQF A;  4KDL A;  1DMS A;  2G6G A;  3GTQ A;  2JA5 A;  5T5M D;  3ML1 A;  4CS0 A;  1E5V A;  3IR5 A;  1R7R A;  1Y1V A;  1WLF A;  1UHD A;  3QQ7 A;  1G8K A;  1K83 A;  2PNW A;  2C45 A;  2V45 A;  1E60 A;  4AYB A;  1OGY A;  4GA5 A;  1TWF A;  2GAE A;  5FTK A;  2JIO A;  1AW8 B;  5C18 A;  1E18 A;  1S3S A;  2VPW A;  1PT1 A;  2VPX A;  1PQH A;  3CZB A;  3GTJ A;  5FTN A;  2WAQ A;  1TWG A;  2PJJ A;  4AAY A;  4DMR A;  2R92 A;  2KI8 A;  4RV0 A;  1TWA A;  2PMZ A;  1PT0 A;  3O5A A;  3CF2 A;  3HU3 A;  2IV2 X;  4AZD A;  1ZC1 A;  3GTL A;  3QWZ A;  2JA7 A;  1UHE A;  1TWH A;  1Y4Z A;  2JIR A;  1QCS A;  5EPP A;  2VPZ A;  3GTM A;  2AE0 X;  1Y1W A;  2E7Z A;  4KOD A;  2B63 A;  1PYQ A;  1EU1 A;  1Q16 A;  1ZYR D;  1SMY D;  1IW7 D;  2NVX A;  3DMR A;  2V3V A;  1TWC A;  2JA6 A;  2YUJ A;  1SIW A;  3OUG A;  4QIW A;  5FTM A;  1AA6 A;  3IR7 A;  1QDN A;  3HU1 A;  4C2M A;  2A6E D;  2Y0S A;  1TMO A;  1FDI A;  1PPY A;  1PQE A;  3H0G A;  2E2H A;  3FKI A;  3HU2 A;  1R27 A;  3PLX B;  4KDI A;  1WCM A;  2PJH B;  2VPY A;  5FTL A;  4AOK B;  2JIM A;  3HKZ A;  2PI8 A;  3IR6 A;  1YNN D; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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