1PT1A

Unprocessed pyruvoyl dependent aspartate decarboxylase with histidine 11 mutated to alanine
Total Genus 35
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
35
sequence length
117
structure length
117
Chain Sequence
GSMIRTMLQGKLARVKVTHADLHYEGSCAIDQDFLDAAGILENEAIDIWNVTNGKRFSTYAIAAERGSRIISVNGAAAHCASVGDIVIIASFVTMPDEEARTWRPNVAYFEGDNEMK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Lyase
molecule keywords Aspartate 1-decarboxylase
publication title Structural constraints on protein self-processing in L-aspartate-alpha-decarboxylase
pubmed doi rcsb
source organism Escherichia coli
total genus 35
structure length 117
sequence length 117
chains with identical sequence B
ec nomenclature ec 4.1.1.11: Aspartate 1-decarboxylase.
pdb deposition date 2003-06-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02261 Asp_decarbox Aspartate decarboxylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.40.20 Mainly Beta Beta Barrel Barwin-like endoglucanases Barwin-like endoglucanases 1pt1A00
3TIWA 1TWHA 1TWFA 1TWGA 5T5ID 3HKZA 1UHDA 2V45A 5C1BA 1CR5A 1I50A 3PLXB 4GA6A 1S3SA 1IW7D 1FDOA 2VPXA 1H5NA 4AONB 3HU2A 4D7ZB 4KODA 3CF2A 3OUGA 2NVYA 2IV2X 4AOKB 2EEOB 1UHEA 3QC8A 2E2IA 2JIMA 4KLNA 1PT1A 2Y0SA 4DMRA 1R7RA 2E2HA 1YLEA 1R9TA 2JIOA 2NYAA 3H0GA 5DYIA 1TMOA 4KDIA 1PYUB 5FTMA 3GTKA 1Q16A 1Y1WA 2PJHB 3IR5A 4AAYA 1PT0A 4RV0A 2JA5A 2R93A 3HU3A 1E32A 5DYGA 3QQ7A 2VUMA 1E18A 1WCMA 2DMRA 1DMRA 2JIQA 5FTKA 3GTGA 3TM7B 1KQFA 1E60A 2JA7A 1AA6A 2JIRA 3GTLA 1K83A 1Y4ZA 4C2MA 1QDNA 5EPPA 2JIPA 3GTPA 1KQGA 4CS0A 2VPYA 5FTLA 1E5VA 5GLFA 2KI8A 4GA5A 3ML1A 2B63A 4AYBA 1TWCA 1FDIA 1R27A 2R92A 3GTQA 2WAQA 3CQZA 1TWAA 5B6CA 1G8KA 2VPWA 5C18A 5FTJA 1E61A 1Y5IA 2R7ZA 3GTMA 3QWZA 3IR7A 1I3QA 1PQHA 3IR6A 4KDLA 1AW8B 2JA6A 1EU1A 3DMRA 4CRYG 1OGYA 1G8JA 1SIWA 2VPZA 3QQ8A 3GTJA 2YU9A 3O5AA 1VC3B 1CZ5A 4CRZA 1H0HA 1Y1VA 2NAPA 4AZDA 2NVXA 3FKIA 1PPYA 1SFOA 2PMZA 2WB1A 1PQFA 1PQEA 4KO8A 3GTOA 1DMSA 5T5MD 1PYQA 3HU1A 1QCSA 4QIWA 2E7ZA 5FTNA 1CZ4A 2V3VA 2C45A 1WLFA
chains in the Genus database with same CATH superfamily
3TIWA 1N10A 1TWHA 1TWFA 3X2IA 1TWGA 3X2MA 5T5ID 3HKZA 1UHDA 2V45A 4AVRA 5C1BA 1WC2A 1CR5A 1YNND 1I50A 3PLXB 3X2OA 4GA6A 1S3SA 1IW7D 1FDOA 2HCZX 2VPXA 1H5NA 4AONB 3HU2A 3X2JA 4D7ZB 4KODA 3CF2A 3OUGA 2NVYA 2IV2X 3D30A 3X2PA 4AOKB 2EEOB 1UHEA 3QC8A 2E2IA 2JIMA 1HD5A 4KLNA 1YNJD 1PT1A 2Y0SA 4JP6A 2CW0D 4DMRA 1R7RA 2E2HA 1YLEA 3SULA 3CZBA 1R9TA 2JIOA 2NYAA 4FG2A 3H0GA 5GM9A 5DYIA 1TMOA 4KDIA 5GLXA 4NOHA 1PYUB 2GAEA 5FTMA 3GTKA 1Q16A 1Y1WA 2PJHB 3IR5A 4AAYA 1PT0A 4RV0A 1L8FA 4JS7A 2JA5A 3X2KA 1BW3A 2R93A 3HU3A 1E32A 3SUKA 5DYGA 3QQ7A 2VUMA 4JCWA 1E18A 1WCMA 2DMRA 1BW4A 1DMRA 2JIQA 5FTKA 3GTGA 3TM7B 3X2HA 1KQFA 2O5JD 1E60A 2JA7A 1AA6A 2JIRA 2A68D 1K83A 3GTLA 1Y4ZA 2YUJA 2BH0A 4JJOA 4C2MA 3SUMA 1QDNA 5EPPA 4ZM7A 4FERA 2JIPA 3GTPA 1KQGA 4CS0A 2VPYA 5FTLA 2AE0X 1E5VA 5GLFA 2KI8A 4GA5A 3ML1A 1SMYD 2B63A 4AYBA 2PICA 1TWCA 1FDIA 1R27A 2R92A 4ENGA 3GTQA 1OA9A 2WAQA 3CQZA 2A6HD 1TWAA 4JP7A 5B6CA 1G8KA 2A6ED 2VPWA 4FG4A 5C18A 5FTJA 1E61A 1Y5IA 1OA7A 1ZYRD 3GTMA 2R7ZA 3QWZA 2G5DA 3IR7A 3X2LA 1I3QA 1PQHA 3M3GA 2BE5D 2PJJA 4FFTA 3IR6A 2G6GA 4KDLA 1AW8B 2PNWA 2JA6A 1EU1A 3DMRA 4CRYG 1OGYA 1G8JA 1SIWA 2VPZA 3ENGA 2A69D 3QQ8A 3GTJA 2YU9A 3O5AA 3X2GA 1VC3B 1CZ5A 4CRZA 2KQAA 1H0HA 1Y1VA 2NAPA 4AZDA 2NVXA 3FKIA 1PPYA 5GLYA 1SFOA 2PMZA 2WB1A 1PQFA 1PQEA 4KO8A 3GTOA 1DMSA 5T5MD 4L48A 1PYQA 3HU1A 1QCSA 1ZC1A 4QIWA 2E7ZA 5FTNA 5H4UA 1CZ4A 2V3VA 3X2NA 2C45A 3SUJA 2ENGA 2PI8A 1WLFA
chains in the Genus database with same CATH topology
3TIWA 1TWHA 1TWFA 1TWGA 5T5ID 3HKZA 1UHDA 2V45A 5C1BA 1CR5A 1YNND 1I50A 3PLXB 4GA6A 1S3SA 1IW7D 1FDOA 2VPXA 1H5NA 4AONB 3HU2A 4D7ZB 4KODA 3CF2A 3OUGA 2NVYA 2IV2X 4AOKB 2EEOB 1UHEA 3QC8A 2E2IA 2JIMA 4KLNA 1YNJD 1PT1A 2Y0SA 2CW0D 4DMRA 1R7RA 2E2HA 1YLEA 1R9TA 3CZBA 2JIOA 2NYAA 3H0GA 5DYIA 1TMOA 4KDIA 4NOHA 1PYUB 2GAEA 5FTMA 3GTKA 1Q16A 1Y1WA 2PJHB 3IR5A 4AAYA 1PT0A 4RV0A 2JA5A 2R93A 3HU3A 1E32A 5DYGA 3QQ7A 2VUMA 1E18A 1WCMA 2DMRA 1DMRA 2JIQA 5FTKA 3GTGA 3TM7B 1KQFA 2O5JD 1E60A 2JA7A 1AA6A 2JIRA 2A68D 1K83A 3GTLA 1Y4ZA 2YUJA 4C2MA 1QDNA 5EPPA 2JIPA 3GTPA 1KQGA 4CS0A 2VPYA 5FTLA 2AE0X 1E5VA 5GLFA 2KI8A 4GA5A 3ML1A 1SMYD 2B63A 4AYBA 2PICA 1TWCA 1FDIA 1R27A 2R92A 3GTQA 2WAQA 3CQZA 2A6HD 1TWAA 5B6CA 1G8KA 2A6ED 2VPWA 5C18A 5FTJA 1E61A 1Y5IA 2R7ZA 1ZYRD 3GTMA 3QWZA 2G5DA 3IR7A 1I3QA 1PQHA 2BE5D 2PJJA 3IR6A 2G6GA 4KDLA 1AW8B 2PNWA 2JA6A 1EU1A 3DMRA 4CRYG 1OGYA 1G8JA 1SIWA 2VPZA 3QQ8A 2A69D 3GTJA 2YU9A 3O5AA 1VC3B 1CZ5A 4CRZA 1H0HA 1Y1VA 2NAPA 4AZDA 2NVXA 3FKIA 1PPYA 1SFOA 2PMZA 2WB1A 1PQFA 1PQEA 4KO8A 3GTOA 1DMSA 5T5MD 1PYQA 3HU1A 1QCSA 1ZC1A 4QIWA 2E7ZA 5FTNA 1CZ4A 2V3VA 2C45A 2PI8A 1WLFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3TIW A;  1TWH A;  1TWF A;  1TWG A;  5T5I D;  3HKZ A;  1UHD A;  2V45 A;  5C1B A;  1CR5 A;  1I50 A;  3PLX B;  4GA6 A;  1S3S A;  1IW7 D;  1FDO A;  2VPX A;  1H5N A;  4AON B;  3HU2 A;  4D7Z B;  4KOD A;  3CF2 A;  3OUG A;  2NVY A;  2IV2 X;  4AOK B;  2EEO B;  1UHE A;  3QC8 A;  2E2I A;  2JIM A;  4KLN A;  1PT1 A;  2Y0S A;  4DMR A;  1R7R A;  2E2H A;  1YLE A;  1R9T A;  2JIO A;  2NYA A;  3H0G A;  5DYI A;  1TMO A;  4KDI A;  1PYU B;  5FTM A;  3GTK A;  1Q16 A;  1Y1W A;  2PJH B;  3IR5 A;  4AAY A;  1PT0 A;  4RV0 A;  2JA5 A;  2R93 A;  3HU3 A;  1E32 A;  5DYG A;  3QQ7 A;  2VUM A;  1E18 A;  1WCM A;  2DMR A;  1DMR A;  2JIQ A;  5FTK A;  3GTG A;  3TM7 B;  1KQF A;  1E60 A;  2JA7 A;  1AA6 A;  2JIR A;  3GTL A;  1K83 A;  1Y4Z A;  4C2M A;  1QDN A;  5EPP A;  2JIP A;  3GTP A;  1KQG A;  4CS0 A;  2VPY A;  5FTL A;  1E5V A;  5GLF A;  2KI8 A;  4GA5 A;  3ML1 A;  2B63 A;  4AYB A;  1TWC A;  1FDI A;  1R27 A;  2R92 A;  3GTQ A;  2WAQ A;  3CQZ A;  1TWA A;  5B6C A;  1G8K A;  2VPW A;  5C18 A;  5FTJ A;  1E61 A;  1Y5I A;  2R7Z A;  3GTM A;  3QWZ A;  3IR7 A;  1I3Q A;  1PQH A;  3IR6 A;  4KDL A;  1AW8 B;  2JA6 A;  1EU1 A;  3DMR A;  4CRY G;  1OGY A;  1G8J A;  1SIW A;  2VPZ A;  3QQ8 A;  3GTJ A;  2YU9 A;  3O5A A;  1VC3 B;  1CZ5 A;  4CRZ A;  1H0H A;  1Y1V A;  2NAP A;  4AZD A;  2NVX A;  3FKI A;  1PPY A;  1SFO A;  2PMZ A;  2WB1 A;  1PQF A;  1PQE A;  4KO8 A;  3GTO A;  1DMS A;  5T5M D;  1PYQ A;  3HU1 A;  1QCS A;  4QIW A;  2E7Z A;  5FTN A;  1CZ4 A;  2V3V A;  2C45 A;  1WLF A; 
#chains in the Genus database with same CATH topology
 3TIW A;  1N10 A;  1TWH A;  1TWF A;  3X2I A;  1TWG A;  3X2M A;  5T5I D;  3HKZ A;  1UHD A;  2V45 A;  4AVR A;  5C1B A;  1WC2 A;  1CR5 A;  1YNN D;  1I50 A;  3PLX B;  3X2O A;  4GA6 A;  1S3S A;  1IW7 D;  1FDO A;  2HCZ X;  2VPX A;  1H5N A;  4AON B;  3HU2 A;  3X2J A;  4D7Z B;  4KOD A;  3CF2 A;  3OUG A;  2NVY A;  2IV2 X;  3D30 A;  3X2P A;  4AOK B;  2EEO B;  1UHE A;  3QC8 A;  2E2I A;  2JIM A;  1HD5 A;  4KLN A;  1YNJ D;  1PT1 A;  2Y0S A;  4JP6 A;  2CW0 D;  4DMR A;  1R7R A;  2E2H A;  1YLE A;  3SUL A;  3CZB A;  1R9T A;  2JIO A;  2NYA A;  4FG2 A;  3H0G A;  5GM9 A;  5DYI A;  1TMO A;  4KDI A;  5GLX A;  4NOH A;  1PYU B;  2GAE A;  5FTM A;  3GTK A;  1Q16 A;  1Y1W A;  2PJH B;  3IR5 A;  4AAY A;  1PT0 A;  4RV0 A;  1L8F A;  4JS7 A;  2JA5 A;  3X2K A;  1BW3 A;  2R93 A;  3HU3 A;  1E32 A;  3SUK A;  5DYG A;  3QQ7 A;  2VUM A;  4JCW A;  1E18 A;  1WCM A;  2DMR A;  1BW4 A;  1DMR A;  2JIQ A;  5FTK A;  3GTG A;  3TM7 B;  3X2H A;  1KQF A;  2O5J D;  1E60 A;  2JA7 A;  1AA6 A;  2JIR A;  2A68 D;  1K83 A;  3GTL A;  1Y4Z A;  2YUJ A;  2BH0 A;  4JJO A;  4C2M A;  3SUM A;  1QDN A;  5EPP A;  4ZM7 A;  4FER A;  2JIP A;  3GTP A;  1KQG A;  4CS0 A;  2VPY A;  5FTL A;  2AE0 X;  1E5V A;  5GLF A;  2KI8 A;  4GA5 A;  3ML1 A;  1SMY D;  2B63 A;  4AYB A;  2PIC A;  1TWC A;  1FDI A;  1R27 A;  2R92 A;  4ENG A;  3GTQ A;  1OA9 A;  2WAQ A;  3CQZ A;  2A6H D;  1TWA A;  4JP7 A;  5B6C A;  1G8K A;  2A6E D;  2VPW A;  4FG4 A;  5C18 A;  5FTJ A;  1E61 A;  1Y5I A;  1OA7 A;  1ZYR D;  3GTM A;  2R7Z A;  3QWZ A;  2G5D A;  3IR7 A;  3X2L A;  1I3Q A;  1PQH A;  3M3G A;  2BE5 D;  2PJJ A;  4FFT A;  3IR6 A;  2G6G A;  4KDL A;  1AW8 B;  2PNW A;  2JA6 A;  1EU1 A;  3DMR A;  4CRY G;  1OGY A;  1G8J A;  1SIW A;  2VPZ A;  3ENG A;  2A69 D;  3QQ8 A;  3GTJ A;  2YU9 A;  3O5A A;  3X2G A;  1VC3 B;  1CZ5 A;  4CRZ A;  2KQA A;  1H0H A;  1Y1V A;  2NAP A;  4AZD A;  2NVX A;  3FKI A;  1PPY A;  5GLY A;  1SFO A;  2PMZ A;  2WB1 A;  1PQF A;  1PQE A;  4KO8 A;  3GTO A;  1DMS A;  5T5M D;  4L48 A;  1PYQ A;  3HU1 A;  1QCS A;  1ZC1 A;  4QIW A;  2E7Z A;  5FTN A;  5H4U A;  1CZ4 A;  2V3V A;  3X2N A;  2C45 A;  3SUJ A;  2ENG A;  2PI8 A;  1WLF A; 
#chains in the Genus database with same CATH homology
 3TIW A;  1TWH A;  1TWF A;  1TWG A;  5T5I D;  3HKZ A;  1UHD A;  2V45 A;  5C1B A;  1CR5 A;  1YNN D;  1I50 A;  3PLX B;  4GA6 A;  1S3S A;  1IW7 D;  1FDO A;  2VPX A;  1H5N A;  4AON B;  3HU2 A;  4D7Z B;  4KOD A;  3CF2 A;  3OUG A;  2NVY A;  2IV2 X;  4AOK B;  2EEO B;  1UHE A;  3QC8 A;  2E2I A;  2JIM A;  4KLN A;  1YNJ D;  1PT1 A;  2Y0S A;  2CW0 D;  4DMR A;  1R7R A;  2E2H A;  1YLE A;  1R9T A;  3CZB A;  2JIO A;  2NYA A;  3H0G A;  5DYI A;  1TMO A;  4KDI A;  4NOH A;  1PYU B;  2GAE A;  5FTM A;  3GTK A;  1Q16 A;  1Y1W A;  2PJH B;  3IR5 A;  4AAY A;  1PT0 A;  4RV0 A;  2JA5 A;  2R93 A;  3HU3 A;  1E32 A;  5DYG A;  3QQ7 A;  2VUM A;  1E18 A;  1WCM A;  2DMR A;  1DMR A;  2JIQ A;  5FTK A;  3GTG A;  3TM7 B;  1KQF A;  2O5J D;  1E60 A;  2JA7 A;  1AA6 A;  2JIR A;  2A68 D;  1K83 A;  3GTL A;  1Y4Z A;  2YUJ A;  4C2M A;  1QDN A;  5EPP A;  2JIP A;  3GTP A;  1KQG A;  4CS0 A;  2VPY A;  5FTL A;  2AE0 X;  1E5V A;  5GLF A;  2KI8 A;  4GA5 A;  3ML1 A;  1SMY D;  2B63 A;  4AYB A;  2PIC A;  1TWC A;  1FDI A;  1R27 A;  2R92 A;  3GTQ A;  2WAQ A;  3CQZ A;  2A6H D;  1TWA A;  5B6C A;  1G8K A;  2A6E D;  2VPW A;  5C18 A;  5FTJ A;  1E61 A;  1Y5I A;  2R7Z A;  1ZYR D;  3GTM A;  3QWZ A;  2G5D A;  3IR7 A;  1I3Q A;  1PQH A;  2BE5 D;  2PJJ A;  3IR6 A;  2G6G A;  4KDL A;  1AW8 B;  2PNW A;  2JA6 A;  1EU1 A;  3DMR A;  4CRY G;  1OGY A;  1G8J A;  1SIW A;  2VPZ A;  3QQ8 A;  2A69 D;  3GTJ A;  2YU9 A;  3O5A A;  1VC3 B;  1CZ5 A;  4CRZ A;  1H0H A;  1Y1V A;  2NAP A;  4AZD A;  2NVX A;  3FKI A;  1PPY A;  1SFO A;  2PMZ A;  2WB1 A;  1PQF A;  1PQE A;  4KO8 A;  3GTO A;  1DMS A;  5T5M D;  1PYQ A;  3HU1 A;  1QCS A;  1ZC1 A;  4QIW A;  2E7Z A;  5FTN A;  1CZ4 A;  2V3V A;  2C45 A;  2PI8 A;  1WLF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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