4AZDA

T57v mutant of aspartate decarboxylase
Total Genus 35
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
35
sequence length
122
structure length
122
Chain Sequence
VPRGSMIRTMLQGKLHRVKVTHADLHYEGSCAIDQDFLDAAGILENEAIDIWNVTNGKRFSVYAIAAERGSRIISVNGAAAHCASVGDIVIIASFVTMPDEEARTWRPNVAYFEGDNEMKRT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Threonine 57 is Required for the Post-Translational Activation of Escherichia Coli Aspartate Alpha-Decarboxylase
pubmed doi rcsb
source organism Escherichia coli
molecule tags Lyase
molecule keywords ASPARTATE 1-DECARBOXYLASE
total genus 35
structure length 122
sequence length 122
chains with identical sequence B
ec nomenclature ec 4.1.1.11: Aspartate 1-decarboxylase.
pdb deposition date 2012-06-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02261 Asp_decarbox Aspartate decarboxylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.40.20 Mainly Beta Beta Barrel Barwin-like endoglucanases Barwin-like endoglucanases 4azdA00
4KODA 2V3VA 2VPZA 2JIRA 3GTGA 1PYUB 1WLFA 4AOKB 3HU2A 2V45A 1PQFA 5B6CA 4KLNA 5T5MD 3TM7B 1K83A 1TWHA 2JIMA 3PLXB 3GTLA 1YLEA 5GLFA 3QC8A 3IR6A 1TWGA 4KDLA 2R92A 1CZ4A 1TWFA 1Q16A 1IW7D 2NVYA 1E18A 2VPYA 2B63A 3GTQA 1KQGA 1EU1A 4RV0A 1R27A 1KQFA 3DMRA 1R9TA 2YU9A 2JA5A 2PMZA 3IR5A 2DMRA 4GA5A 1PPYA 4GA6A 1PT0A 2VUMA 2JIPA 2JIQA 3O5AA 1SIWA 2EEOB 4AONB 1H5NA 2WB1A 2R93A 4DMRA 1CR5A 4AZDA 2KI8A 1OGYA 1WCMA 1I3QA 1G8JA 3TIWA 3GTJA 4AYBA 3HU1A 3HU3A 1SFOA 4KO8A 1PQHA 1Y5IA 3GTKA 5FTJA 2JIOA 2JA7A 1CZ5A 3HKZA 1R7RA 5FTKA 1I50A 4AAYA 1E60A 5T5ID 1DMSA 1Y1VA 1AW8B 1FDIA 3QQ7A 4KDIA 3OUGA 3GTOA 5FTNA 5DYGA 1DMRA 1PYQA 1AA6A 1E32A 4CS0A 3H0GA 2E2IA 3GTPA 2R7ZA 2VPWA 5EPPA 4CRZA 1QDNA 3IR7A 1TWCA 1S3SA 1PQEA 1VC3B 3QQ8A 1FDOA 1UHDA 2E7ZA 3CQZA 1Y4ZA 1H0HA 5C18A 5FTMA 1UHEA 1G8KA 1Y1WA 1E61A 2NAPA 2Y0SA 5FTLA 5DYIA 3GTMA 3CF2A 2NVXA 2VPXA 1PT1A 2NYAA 1TWAA 4D7ZB 4C2MA 2C45A 4QIWA 3QWZA 1TMOA 1E5VA 3FKIA 5C1BA 2E2HA 4CRYG 2JA6A 2IV2X 2WAQA 2PJHB 3ML1A 1QCSA
chains in the Genus database with same CATH superfamily
4KODA 2V3VA 2VPZA 2JIRA 4NOHA 3GTGA 1PYUB 1WLFA 4AOKB 3SUKA 3HU2A 2V45A 1PQFA 5B6CA 2HCZX 4KLNA 5T5MD 3TM7B 1TWHA 3X2LA 1K83A 2A68D 4FERA 2GAEA 2JIMA 1BW3A 3PLXB 3GTLA 1YLEA 5GLFA 3QC8A 3IR6A 1N10A 1SMYD 2A69D 1TWGA 4KDLA 2R92A 1CZ4A 1TWFA 3X2KA 2BH0A 1Q16A 1IW7D 2NVYA 4JP7A 3X2IA 1E18A 2VPYA 2B63A 3GTQA 1KQGA 2G5DA 1EU1A 4RV0A 1R27A 2A6HD 1KQFA 3DMRA 4JP6A 1R9TA 2YU9A 1OA7A 2JA5A 2PMZA 3IR5A 2DMRA 4GA5A 1PPYA 4GA6A 1PT0A 4FG2A 2VUMA 2JIPA 2JIQA 3O5AA 1SIWA 2EEOB 1YNJD 2CW0D 4JJOA 4AONB 1H5NA 2WB1A 3D30A 3M3GA 3SULA 2R93A 4DMRA 1CR5A 4JCWA 4AZDA 2KI8A 1OGYA 1WCMA 2YUJA 3SUJA 1I3QA 1G8JA 3TIWA 3SUMA 5GLXA 3GTJA 4JS7A 4AYBA 3HU1A 1ZC1A 3HU3A 1SFOA 4KO8A 1PQHA 1Y5IA 1HD5A 3GTKA 5FTJA 2JIOA 2JA7A 2O5JD 1CZ5A 3HKZA 1L8FA 4L48A 1R7RA 5FTKA 3ENGA 3CZBA 2PI8A 1I50A 4AAYA 1E60A 3X2OA 5T5ID 1DMSA 1Y1VA 1AW8B 1FDIA 2A6ED 3QQ7A 4KDIA 3OUGA 3GTOA 4ENGA 4FG4A 5FTNA 5DYGA 1DMRA 1ZYRD 1PYQA 1AA6A 1E32A 4CS0A 1BW4A 3H0GA 2E2IA 3GTPA 2ENGA 2R7ZA 2VPWA 1OA9A 5EPPA 4CRZA 1QDNA 3IR7A 1TWCA 1S3SA 4FFTA 1PQEA 2PNWA 3X2NA 1VC3B 3X2HA 3QQ8A 2AE0X 1FDOA 1UHDA 2E7ZA 4AVRA 3CQZA 1Y4ZA 1H0HA 5C18A 5FTMA 1UHEA 1G8KA 4ZM7A 5GLYA 1Y1WA 1E61A 2NAPA 2Y0SA 2PICA 5DYIA 5FTLA 3X2GA 3GTMA 3CF2A 2NVXA 2VPXA 1PT1A 2NYAA 5GM9A 3X2JA 1TWAA 2PJJA 3X2PA 4D7ZB 4C2MA 2C45A 2BE5D 4QIWA 3QWZA 1TMOA 1E5VA 3FKIA 3X2MA 5C1BA 2E2HA 2KQAA 5H4UA 4CRYG 1YNND 2IV2X 2JA6A 1WC2A 2WAQA 2PJHB 3ML1A 2G6GA 1QCSA
chains in the Genus database with same CATH topology
4KODA 2V3VA 2VPZA 2JIRA 4NOHA 3GTGA 1PYUB 1WLFA 4AOKB 3HU2A 2V45A 1PQFA 5B6CA 4KLNA 5T5MD 3TM7B 1K83A 1TWHA 2A68D 2GAEA 2JIMA 3PLXB 3GTLA 1YLEA 5GLFA 3QC8A 3IR6A 1SMYD 2A69D 1TWGA 4KDLA 2R92A 1CZ4A 1TWFA 1Q16A 1IW7D 2NVYA 1E18A 2VPYA 2B63A 3GTQA 1KQGA 2G5DA 1EU1A 4RV0A 1R27A 2A6HD 1KQFA 3DMRA 1R9TA 2YU9A 2JA5A 2PMZA 3IR5A 2DMRA 4GA5A 1PPYA 4GA6A 1PT0A 2VUMA 2JIPA 2JIQA 3O5AA 1SIWA 2EEOB 1YNJD 2CW0D 4AONB 1H5NA 2WB1A 2R93A 4DMRA 1CR5A 4AZDA 2KI8A 1OGYA 1WCMA 2YUJA 1I3QA 1G8JA 3TIWA 3GTJA 4AYBA 3HU1A 1ZC1A 3HU3A 1SFOA 4KO8A 1PQHA 1Y5IA 3GTKA 5FTJA 2JIOA 2JA7A 2O5JD 1CZ5A 3HKZA 1R7RA 5FTKA 3CZBA 2PI8A 1I50A 4AAYA 1E60A 5T5ID 1DMSA 1Y1VA 1AW8B 1FDIA 2A6ED 3QQ7A 4KDIA 3OUGA 3GTOA 5FTNA 5DYGA 1DMRA 1ZYRD 1PYQA 1AA6A 1E32A 4CS0A 3H0GA 2E2IA 3GTPA 2R7ZA 2VPWA 5EPPA 4CRZA 1QDNA 3IR7A 1TWCA 1S3SA 1PQEA 2PNWA 1VC3B 3QQ8A 2AE0X 1FDOA 1UHDA 2E7ZA 3CQZA 1Y4ZA 1H0HA 5C18A 5FTMA 1UHEA 1G8KA 1Y1WA 1E61A 2NAPA 2Y0SA 2PICA 5DYIA 5FTLA 3GTMA 3CF2A 2NVXA 2VPXA 1PT1A 2NYAA 1TWAA 2PJJA 4D7ZB 4C2MA 2C45A 2BE5D 4QIWA 3QWZA 1TMOA 1E5VA 3FKIA 5C1BA 2E2HA 4CRYG 2JA6A 1YNND 2IV2X 2WAQA 2PJHB 3ML1A 2G6GA 1QCSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4KOD A;  2V3V A;  2VPZ A;  2JIR A;  3GTG A;  1PYU B;  1WLF A;  4AOK B;  3HU2 A;  2V45 A;  1PQF A;  5B6C A;  4KLN A;  5T5M D;  3TM7 B;  1K83 A;  1TWH A;  2JIM A;  3PLX B;  3GTL A;  1YLE A;  5GLF A;  3QC8 A;  3IR6 A;  1TWG A;  4KDL A;  2R92 A;  1CZ4 A;  1TWF A;  1Q16 A;  1IW7 D;  2NVY A;  1E18 A;  2VPY A;  2B63 A;  3GTQ A;  1KQG A;  1EU1 A;  4RV0 A;  1R27 A;  1KQF A;  3DMR A;  1R9T A;  2YU9 A;  2JA5 A;  2PMZ A;  3IR5 A;  2DMR A;  4GA5 A;  1PPY A;  4GA6 A;  1PT0 A;  2VUM A;  2JIP A;  2JIQ A;  3O5A A;  1SIW A;  2EEO B;  4AON B;  1H5N A;  2WB1 A;  2R93 A;  4DMR A;  1CR5 A;  4AZD A;  2KI8 A;  1OGY A;  1WCM A;  1I3Q A;  1G8J A;  3TIW A;  3GTJ A;  4AYB A;  3HU1 A;  3HU3 A;  1SFO A;  4KO8 A;  1PQH A;  1Y5I A;  3GTK A;  5FTJ A;  2JIO A;  2JA7 A;  1CZ5 A;  3HKZ A;  1R7R A;  5FTK A;  1I50 A;  4AAY A;  1E60 A;  5T5I D;  1DMS A;  1Y1V A;  1AW8 B;  1FDI A;  3QQ7 A;  4KDI A;  3OUG A;  3GTO A;  5FTN A;  5DYG A;  1DMR A;  1PYQ A;  1AA6 A;  1E32 A;  4CS0 A;  3H0G A;  2E2I A;  3GTP A;  2R7Z A;  2VPW A;  5EPP A;  4CRZ A;  1QDN A;  3IR7 A;  1TWC A;  1S3S A;  1PQE A;  1VC3 B;  3QQ8 A;  1FDO A;  1UHD A;  2E7Z A;  3CQZ A;  1Y4Z A;  1H0H A;  5C18 A;  5FTM A;  1UHE A;  1G8K A;  1Y1W A;  1E61 A;  2NAP A;  2Y0S A;  5FTL A;  5DYI A;  3GTM A;  3CF2 A;  2NVX A;  2VPX A;  1PT1 A;  2NYA A;  1TWA A;  4D7Z B;  4C2M A;  2C45 A;  4QIW A;  3QWZ A;  1TMO A;  1E5V A;  3FKI A;  5C1B A;  2E2H A;  4CRY G;  2JA6 A;  2IV2 X;  2WAQ A;  2PJH B;  3ML1 A;  1QCS A; 
#chains in the Genus database with same CATH topology
 4KOD A;  2V3V A;  2VPZ A;  2JIR A;  4NOH A;  3GTG A;  1PYU B;  1WLF A;  4AOK B;  3SUK A;  3HU2 A;  2V45 A;  1PQF A;  5B6C A;  2HCZ X;  4KLN A;  5T5M D;  3TM7 B;  1TWH A;  3X2L A;  1K83 A;  2A68 D;  4FER A;  2GAE A;  2JIM A;  1BW3 A;  3PLX B;  3GTL A;  1YLE A;  5GLF A;  3QC8 A;  3IR6 A;  1N10 A;  1SMY D;  2A69 D;  1TWG A;  4KDL A;  2R92 A;  1CZ4 A;  1TWF A;  3X2K A;  2BH0 A;  1Q16 A;  1IW7 D;  2NVY A;  4JP7 A;  3X2I A;  1E18 A;  2VPY A;  2B63 A;  3GTQ A;  1KQG A;  2G5D A;  1EU1 A;  4RV0 A;  1R27 A;  2A6H D;  1KQF A;  3DMR A;  4JP6 A;  1R9T A;  2YU9 A;  1OA7 A;  2JA5 A;  2PMZ A;  3IR5 A;  2DMR A;  4GA5 A;  1PPY A;  4GA6 A;  1PT0 A;  4FG2 A;  2VUM A;  2JIP A;  2JIQ A;  3O5A A;  1SIW A;  2EEO B;  1YNJ D;  2CW0 D;  4JJO A;  4AON B;  1H5N A;  2WB1 A;  3D30 A;  3M3G A;  3SUL A;  2R93 A;  4DMR A;  1CR5 A;  4JCW A;  4AZD A;  2KI8 A;  1OGY A;  1WCM A;  2YUJ A;  3SUJ A;  1I3Q A;  1G8J A;  3TIW A;  3SUM A;  5GLX A;  3GTJ A;  4JS7 A;  4AYB A;  3HU1 A;  1ZC1 A;  3HU3 A;  1SFO A;  4KO8 A;  1PQH A;  1Y5I A;  1HD5 A;  3GTK A;  5FTJ A;  2JIO A;  2JA7 A;  2O5J D;  1CZ5 A;  3HKZ A;  1L8F A;  4L48 A;  1R7R A;  5FTK A;  3ENG A;  3CZB A;  2PI8 A;  1I50 A;  4AAY A;  1E60 A;  3X2O A;  5T5I D;  1DMS A;  1Y1V A;  1AW8 B;  1FDI A;  2A6E D;  3QQ7 A;  4KDI A;  3OUG A;  3GTO A;  4ENG A;  4FG4 A;  5FTN A;  5DYG A;  1DMR A;  1ZYR D;  1PYQ A;  1AA6 A;  1E32 A;  4CS0 A;  1BW4 A;  3H0G A;  2E2I A;  3GTP A;  2ENG A;  2R7Z A;  2VPW A;  1OA9 A;  5EPP A;  4CRZ A;  1QDN A;  3IR7 A;  1TWC A;  1S3S A;  4FFT A;  1PQE A;  2PNW A;  3X2N A;  1VC3 B;  3X2H A;  3QQ8 A;  2AE0 X;  1FDO A;  1UHD A;  2E7Z A;  4AVR A;  3CQZ A;  1Y4Z A;  1H0H A;  5C18 A;  5FTM A;  1UHE A;  1G8K A;  4ZM7 A;  5GLY A;  1Y1W A;  1E61 A;  2NAP A;  2Y0S A;  2PIC A;  5DYI A;  5FTL A;  3X2G A;  3GTM A;  3CF2 A;  2NVX A;  2VPX A;  1PT1 A;  2NYA A;  5GM9 A;  3X2J A;  1TWA A;  2PJJ A;  3X2P A;  4D7Z B;  4C2M A;  2C45 A;  2BE5 D;  4QIW A;  3QWZ A;  1TMO A;  1E5V A;  3FKI A;  3X2M A;  5C1B A;  2E2H A;  2KQA A;  5H4U A;  4CRY G;  1YNN D;  2IV2 X;  2JA6 A;  1WC2 A;  2WAQ A;  2PJH B;  3ML1 A;  2G6G A;  1QCS A; 
#chains in the Genus database with same CATH homology
 4KOD A;  2V3V A;  2VPZ A;  2JIR A;  4NOH A;  3GTG A;  1PYU B;  1WLF A;  4AOK B;  3HU2 A;  2V45 A;  1PQF A;  5B6C A;  4KLN A;  5T5M D;  3TM7 B;  1K83 A;  1TWH A;  2A68 D;  2GAE A;  2JIM A;  3PLX B;  3GTL A;  1YLE A;  5GLF A;  3QC8 A;  3IR6 A;  1SMY D;  2A69 D;  1TWG A;  4KDL A;  2R92 A;  1CZ4 A;  1TWF A;  1Q16 A;  1IW7 D;  2NVY A;  1E18 A;  2VPY A;  2B63 A;  3GTQ A;  1KQG A;  2G5D A;  1EU1 A;  4RV0 A;  1R27 A;  2A6H D;  1KQF A;  3DMR A;  1R9T A;  2YU9 A;  2JA5 A;  2PMZ A;  3IR5 A;  2DMR A;  4GA5 A;  1PPY A;  4GA6 A;  1PT0 A;  2VUM A;  2JIP A;  2JIQ A;  3O5A A;  1SIW A;  2EEO B;  1YNJ D;  2CW0 D;  4AON B;  1H5N A;  2WB1 A;  2R93 A;  4DMR A;  1CR5 A;  4AZD A;  2KI8 A;  1OGY A;  1WCM A;  2YUJ A;  1I3Q A;  1G8J A;  3TIW A;  3GTJ A;  4AYB A;  3HU1 A;  1ZC1 A;  3HU3 A;  1SFO A;  4KO8 A;  1PQH A;  1Y5I A;  3GTK A;  5FTJ A;  2JIO A;  2JA7 A;  2O5J D;  1CZ5 A;  3HKZ A;  1R7R A;  5FTK A;  3CZB A;  2PI8 A;  1I50 A;  4AAY A;  1E60 A;  5T5I D;  1DMS A;  1Y1V A;  1AW8 B;  1FDI A;  2A6E D;  3QQ7 A;  4KDI A;  3OUG A;  3GTO A;  5FTN A;  5DYG A;  1DMR A;  1ZYR D;  1PYQ A;  1AA6 A;  1E32 A;  4CS0 A;  3H0G A;  2E2I A;  3GTP A;  2R7Z A;  2VPW A;  5EPP A;  4CRZ A;  1QDN A;  3IR7 A;  1TWC A;  1S3S A;  1PQE A;  2PNW A;  1VC3 B;  3QQ8 A;  2AE0 X;  1FDO A;  1UHD A;  2E7Z A;  3CQZ A;  1Y4Z A;  1H0H A;  5C18 A;  5FTM A;  1UHE A;  1G8K A;  1Y1W A;  1E61 A;  2NAP A;  2Y0S A;  2PIC A;  5DYI A;  5FTL A;  3GTM A;  3CF2 A;  2NVX A;  2VPX A;  1PT1 A;  2NYA A;  1TWA A;  2PJJ A;  4D7Z B;  4C2M A;  2C45 A;  2BE5 D;  4QIW A;  3QWZ A;  1TMO A;  1E5V A;  3FKI A;  5C1B A;  2E2H A;  4CRY G;  2JA6 A;  1YNN D;  2IV2 X;  2WAQ A;  2PJH B;  3ML1 A;  2G6G A;  1QCS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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