4AZDA

T57v mutant of aspartate decarboxylase
Total Genus 35
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
35
sequence length
122
structure length
122
Chain Sequence
VPRGSMIRTMLQGKLHRVKVTHADLHYEGSCAIDQDFLDAAGILENEAIDIWNVTNGKRFSVYAIAAERGSRIISVNGAAAHCASVGDIVIIASFVTMPDEEARTWRPNVAYFEGDNEMKRT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Threonine 57 is Required for the Post-Translational Activation of Escherichia Coli Aspartate Alpha-Decarboxylase
pubmed doi rcsb
source organism Escherichia coli
molecule tags Lyase
molecule keywords ASPARTATE 1-DECARBOXYLASE
total genus 35
structure length 122
sequence length 122
chains with identical sequence B
ec nomenclature ec 4.1.1.11: Aspartate 1-decarboxylase.
pdb deposition date 2012-06-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02261 Asp_decarbox Aspartate decarboxylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.40.20 Mainly Beta Beta Barrel Barwin-like endoglucanases Barwin-like endoglucanases 4azdA00
1SIWA 1PYUB 5C18A 4KDLA 5GLFA 3GTJA 1TWAA 1Y5IA 1H5NA 2KI8A 2NVYA 1I50A 2R93A 4CRYG 5EPPA 2JIQA 2JIPA 4KDIA 2VUMA 5T5ID 5FTLA 1PPYA 1YLEA 3HKZA 5DYIA 1FDIA 3TM7B 1Y4ZA 3O5AA 3GTKA 1QDNA 3OUGA 3CQZA 1I3QA 1CZ5A 1UHDA 1PT1A 3CF2A 3GTPA 4AYBA 4KODA 1PQHA 1QCSA 1E32A 5FTMA 1Y1WA 1S3SA 1PQFA 2NAPA 1Q16A 1EU1A 1KQFA 1PYQA 5T5MD 3GTQA 1TWGA 2IV2X 5FTKA 1TWFA 3QQ8A 4C2MA 1R9TA 3GTMA 4KLNA 3PLXB 3IR7A 3IR5A 2VPZA 2E2HA 1E18A 1KQGA 2E2IA 1G8JA 2YU9A 2WAQA 2JIRA 4GA6A 2R7ZA 1WLFA 2VPXA 1CZ4A 2JA5A 4GA5A 5FTJA 1TMOA 1E5VA 1PT0A 3HU1A 4QIWA 1AA6A 2B63A 2PJHB 1R7RA 1H0HA 3HU2A 3H0GA 4DMRA 1IW7D 1TWCA 1TWHA 2VPWA 3QWZA 3IR6A 1OGYA 2JIOA 3GTOA 2WB1A 2V3VA 2R92A 2E7ZA 4AZDA 2JA6A 1E61A 1FDOA 1VC3B 3QQ7A 4CRZA 5B6CA 4D7ZB 3GTGA 2NVXA 2JIMA 1WCMA 5DYGA 2V45A 2NYAA 4AOKB 1PQEA 1R27A 1DMSA 1SFOA 2PMZA 2DMRA 4CS0A 1K83A 2JA7A 2Y0SA 1UHEA 3TIWA 3HU3A 4KO8A 5FTNA 2VPYA 1DMRA 2C45A 3QC8A 3FKIA 1Y1VA 1AW8B 4RV0A 4AONB 3GTLA 3ML1A 1CR5A 4AAYA 3DMRA 2EEOB 1E60A 5C1BA 1G8KA
chains in the Genus database with same CATH superfamily
1SIWA 1BW4A 2BH0A 1PYUB 5C18A 4KDLA 5GLFA 2A69D 3GTJA 2PNWA 3X2JA 1TWAA 1Y5IA 1H5NA 2KI8A 2NVYA 1I50A 4AAYA 2R93A 3M3GA 3SULA 4FG2A 4CRYG 5EPPA 3X2OA 2JIQA 4NOHA 2JIPA 4KDIA 2VUMA 5T5ID 5FTLA 1PPYA 2CW0D 1YLEA 2PI8A 3X2LA 3HKZA 5DYIA 1FDIA 2KQAA 3TM7B 1Y4ZA 3O5AA 3GTKA 1QDNA 4AVRA 3OUGA 3CQZA 2G5DA 1I3QA 1CZ5A 1UHDA 1PT1A 4JJOA 5GLXA 3CF2A 1ZC1A 4AYBA 3GTPA 4L48A 4KODA 1PQHA 1QCSA 1E32A 3SUKA 3X2GA 4ZM7A 5FTMA 1Y1WA 1S3SA 1PQFA 2NAPA 1Q16A 1EU1A 1KQFA 1PYQA 5T5MD 2HCZX 3GTQA 1TWGA 4JCWA 2G6GA 2IV2X 4JS7A 2O5JD 5FTKA 1TWFA 3QQ8A 4C2MA 1R9TA 3SUJA 4KLNA 3PLXB 3GTMA 3IR7A 2ENGA 5H4UA 3IR5A 2VPZA 5GLYA 2E2HA 1WC2A 2A6HD 1E18A 1KQGA 2E2IA 1G8JA 4ENGA 2YU9A 2WAQA 2JIRA 4GA6A 2R7ZA 1SMYD 1WLFA 1YNND 2AE0X 3X2PA 4FFTA 2VPXA 1CZ4A 2JA5A 2PICA 4FERA 1YNJD 2YUJA 4GA5A 5FTJA 1TMOA 1E5VA 5GM9A 1PT0A 1BW3A 3HU1A 4QIWA 3CZBA 3X2IA 1AA6A 2B63A 2PJHB 2A68D 3X2KA 1R7RA 1H0HA 3HU2A 3H0GA 2PJJA 4DMRA 3X2HA 1IW7D 1TWCA 1TWHA 2VPWA 3QWZA 3X2MA 3IR6A 1OGYA 2JIOA 1ZYRD 3GTOA 2WB1A 2V3VA 2R92A 2E7ZA 4AZDA 2JA6A 1E61A 3ENGA 1FDOA 1VC3B 3QQ7A 4CRZA 1L8FA 4D7ZB 5B6CA 3GTGA 2NVXA 2JIMA 1WCMA 5DYGA 2V45A 2NYAA 4AOKB 4JP6A 1PQEA 1R27A 1DMSA 1SFOA 2PMZA 2DMRA 4CS0A 1K83A 2JA7A 1OA9A 2Y0SA 1N10A 1UHEA 3TIWA 3HU3A 2BE5D 4KO8A 5FTNA 2VPYA 1DMRA 2C45A 3QC8A 3D30A 3FKIA 1Y1VA 1AW8B 3SUMA 4RV0A 3X2NA 1HD5A 2A6ED 4AONB 3GTLA 4JP7A 2GAEA 3ML1A 1CR5A 1OA7A 4FG4A 3DMRA 2EEOB 1E60A 5C1BA 1G8KA
chains in the Genus database with same CATH topology
1SIWA 1PYUB 5C18A 4KDLA 5GLFA 2A69D 3GTJA 2PNWA 1TWAA 1Y5IA 1H5NA 2KI8A 2NVYA 1I50A 2R93A 4CRYG 5EPPA 2JIQA 4NOHA 2JIPA 4KDIA 2VUMA 5T5ID 5FTLA 1PPYA 2CW0D 1YLEA 2PI8A 3HKZA 5DYIA 1FDIA 3TM7B 1Y4ZA 3O5AA 3GTKA 1QDNA 3OUGA 3CQZA 2G5DA 1I3QA 1CZ5A 1UHDA 1PT1A 3CF2A 1ZC1A 4AYBA 3GTPA 4KODA 1PQHA 1QCSA 1E32A 5FTMA 1Y1WA 1S3SA 1PQFA 2NAPA 1Q16A 1EU1A 1KQFA 1PYQA 5T5MD 3GTQA 1TWGA 2G6GA 2IV2X 2O5JD 5FTKA 1TWFA 3QQ8A 4C2MA 1R9TA 3GTMA 4KLNA 3PLXB 3IR7A 3IR5A 2VPZA 2E2HA 2A6HD 1E18A 1KQGA 2E2IA 1G8JA 2YU9A 2WAQA 2JIRA 4GA6A 2R7ZA 1SMYD 1WLFA 1YNND 2AE0X 2VPXA 1CZ4A 2JA5A 2PICA 1YNJD 2YUJA 4GA5A 5FTJA 1TMOA 1E5VA 1PT0A 3HU1A 4QIWA 3CZBA 1AA6A 2B63A 2PJHB 2A68D 1R7RA 1H0HA 3HU2A 3H0GA 2PJJA 4DMRA 1IW7D 1TWCA 1TWHA 2VPWA 3QWZA 3IR6A 1OGYA 2JIOA 1ZYRD 3GTOA 2WB1A 2V3VA 2R92A 2E7ZA 4AZDA 2JA6A 1E61A 1FDOA 1VC3B 3QQ7A 4CRZA 5B6CA 4D7ZB 3GTGA 2NVXA 2JIMA 1WCMA 5DYGA 2V45A 2NYAA 4AOKB 1PQEA 1R27A 1DMSA 1SFOA 2PMZA 2DMRA 4CS0A 1K83A 2JA7A 2Y0SA 1UHEA 3TIWA 3HU3A 2BE5D 4KO8A 5FTNA 2VPYA 1DMRA 2C45A 3QC8A 3FKIA 1Y1VA 1AW8B 4RV0A 2A6ED 4AONB 3GTLA 2GAEA 3ML1A 1CR5A 4AAYA 3DMRA 2EEOB 1E60A 5C1BA 1G8KA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1SIW A;  1PYU B;  5C18 A;  4KDL A;  5GLF A;  3GTJ A;  1TWA A;  1Y5I A;  1H5N A;  2KI8 A;  2NVY A;  1I50 A;  2R93 A;  4CRY G;  5EPP A;  2JIQ A;  2JIP A;  4KDI A;  2VUM A;  5T5I D;  5FTL A;  1PPY A;  1YLE A;  3HKZ A;  5DYI A;  1FDI A;  3TM7 B;  1Y4Z A;  3O5A A;  3GTK A;  1QDN A;  3OUG A;  3CQZ A;  1I3Q A;  1CZ5 A;  1UHD A;  1PT1 A;  3CF2 A;  3GTP A;  4AYB A;  4KOD A;  1PQH A;  1QCS A;  1E32 A;  5FTM A;  1Y1W A;  1S3S A;  1PQF A;  2NAP A;  1Q16 A;  1EU1 A;  1KQF A;  1PYQ A;  5T5M D;  3GTQ A;  1TWG A;  2IV2 X;  5FTK A;  1TWF A;  3QQ8 A;  4C2M A;  1R9T A;  3GTM A;  4KLN A;  3PLX B;  3IR7 A;  3IR5 A;  2VPZ A;  2E2H A;  1E18 A;  1KQG A;  2E2I A;  1G8J A;  2YU9 A;  2WAQ A;  2JIR A;  4GA6 A;  2R7Z A;  1WLF A;  2VPX A;  1CZ4 A;  2JA5 A;  4GA5 A;  5FTJ A;  1TMO A;  1E5V A;  1PT0 A;  3HU1 A;  4QIW A;  1AA6 A;  2B63 A;  2PJH B;  1R7R A;  1H0H A;  3HU2 A;  3H0G A;  4DMR A;  1IW7 D;  1TWC A;  1TWH A;  2VPW A;  3QWZ A;  3IR6 A;  1OGY A;  2JIO A;  3GTO A;  2WB1 A;  2V3V A;  2R92 A;  2E7Z A;  4AZD A;  2JA6 A;  1E61 A;  1FDO A;  1VC3 B;  3QQ7 A;  4CRZ A;  5B6C A;  4D7Z B;  3GTG A;  2NVX A;  2JIM A;  1WCM A;  5DYG A;  2V45 A;  2NYA A;  4AOK B;  1PQE A;  1R27 A;  1DMS A;  1SFO A;  2PMZ A;  2DMR A;  4CS0 A;  1K83 A;  2JA7 A;  2Y0S A;  1UHE A;  3TIW A;  3HU3 A;  4KO8 A;  5FTN A;  2VPY A;  1DMR A;  2C45 A;  3QC8 A;  3FKI A;  1Y1V A;  1AW8 B;  4RV0 A;  4AON B;  3GTL A;  3ML1 A;  1CR5 A;  4AAY A;  3DMR A;  2EEO B;  1E60 A;  5C1B A;  1G8K A; 
#chains in the Genus database with same CATH topology
 1SIW A;  1BW4 A;  2BH0 A;  1PYU B;  5C18 A;  4KDL A;  5GLF A;  2A69 D;  3GTJ A;  2PNW A;  3X2J A;  1TWA A;  1Y5I A;  1H5N A;  2KI8 A;  2NVY A;  1I50 A;  4AAY A;  2R93 A;  3M3G A;  3SUL A;  4FG2 A;  4CRY G;  5EPP A;  3X2O A;  2JIQ A;  4NOH A;  2JIP A;  4KDI A;  2VUM A;  5T5I D;  5FTL A;  1PPY A;  2CW0 D;  1YLE A;  2PI8 A;  3X2L A;  3HKZ A;  5DYI A;  1FDI A;  2KQA A;  3TM7 B;  1Y4Z A;  3O5A A;  3GTK A;  1QDN A;  4AVR A;  3OUG A;  3CQZ A;  2G5D A;  1I3Q A;  1CZ5 A;  1UHD A;  1PT1 A;  4JJO A;  5GLX A;  3CF2 A;  1ZC1 A;  4AYB A;  3GTP A;  4L48 A;  4KOD A;  1PQH A;  1QCS A;  1E32 A;  3SUK A;  3X2G A;  4ZM7 A;  5FTM A;  1Y1W A;  1S3S A;  1PQF A;  2NAP A;  1Q16 A;  1EU1 A;  1KQF A;  1PYQ A;  5T5M D;  2HCZ X;  3GTQ A;  1TWG A;  4JCW A;  2G6G A;  2IV2 X;  4JS7 A;  2O5J D;  5FTK A;  1TWF A;  3QQ8 A;  4C2M A;  1R9T A;  3SUJ A;  4KLN A;  3PLX B;  3GTM A;  3IR7 A;  2ENG A;  5H4U A;  3IR5 A;  2VPZ A;  5GLY A;  2E2H A;  1WC2 A;  2A6H D;  1E18 A;  1KQG A;  2E2I A;  1G8J A;  4ENG A;  2YU9 A;  2WAQ A;  2JIR A;  4GA6 A;  2R7Z A;  1SMY D;  1WLF A;  1YNN D;  2AE0 X;  3X2P A;  4FFT A;  2VPX A;  1CZ4 A;  2JA5 A;  2PIC A;  4FER A;  1YNJ D;  2YUJ A;  4GA5 A;  5FTJ A;  1TMO A;  1E5V A;  5GM9 A;  1PT0 A;  1BW3 A;  3HU1 A;  4QIW A;  3CZB A;  3X2I A;  1AA6 A;  2B63 A;  2PJH B;  2A68 D;  3X2K A;  1R7R A;  1H0H A;  3HU2 A;  3H0G A;  2PJJ A;  4DMR A;  3X2H A;  1IW7 D;  1TWC A;  1TWH A;  2VPW A;  3QWZ A;  3X2M A;  3IR6 A;  1OGY A;  2JIO A;  1ZYR D;  3GTO A;  2WB1 A;  2V3V A;  2R92 A;  2E7Z A;  4AZD A;  2JA6 A;  1E61 A;  3ENG A;  1FDO A;  1VC3 B;  3QQ7 A;  4CRZ A;  1L8F A;  4D7Z B;  5B6C A;  3GTG A;  2NVX A;  2JIM A;  1WCM A;  5DYG A;  2V45 A;  2NYA A;  4AOK B;  4JP6 A;  1PQE A;  1R27 A;  1DMS A;  1SFO A;  2PMZ A;  2DMR A;  4CS0 A;  1K83 A;  2JA7 A;  1OA9 A;  2Y0S A;  1N10 A;  1UHE A;  3TIW A;  3HU3 A;  2BE5 D;  4KO8 A;  5FTN A;  2VPY A;  1DMR A;  2C45 A;  3QC8 A;  3D30 A;  3FKI A;  1Y1V A;  1AW8 B;  3SUM A;  4RV0 A;  3X2N A;  1HD5 A;  2A6E D;  4AON B;  3GTL A;  4JP7 A;  2GAE A;  3ML1 A;  1CR5 A;  1OA7 A;  4FG4 A;  3DMR A;  2EEO B;  1E60 A;  5C1B A;  1G8K A; 
#chains in the Genus database with same CATH homology
 1SIW A;  1PYU B;  5C18 A;  4KDL A;  5GLF A;  2A69 D;  3GTJ A;  2PNW A;  1TWA A;  1Y5I A;  1H5N A;  2KI8 A;  2NVY A;  1I50 A;  2R93 A;  4CRY G;  5EPP A;  2JIQ A;  4NOH A;  2JIP A;  4KDI A;  2VUM A;  5T5I D;  5FTL A;  1PPY A;  2CW0 D;  1YLE A;  2PI8 A;  3HKZ A;  5DYI A;  1FDI A;  3TM7 B;  1Y4Z A;  3O5A A;  3GTK A;  1QDN A;  3OUG A;  3CQZ A;  2G5D A;  1I3Q A;  1CZ5 A;  1UHD A;  1PT1 A;  3CF2 A;  1ZC1 A;  4AYB A;  3GTP A;  4KOD A;  1PQH A;  1QCS A;  1E32 A;  5FTM A;  1Y1W A;  1S3S A;  1PQF A;  2NAP A;  1Q16 A;  1EU1 A;  1KQF A;  1PYQ A;  5T5M D;  3GTQ A;  1TWG A;  2G6G A;  2IV2 X;  2O5J D;  5FTK A;  1TWF A;  3QQ8 A;  4C2M A;  1R9T A;  3GTM A;  4KLN A;  3PLX B;  3IR7 A;  3IR5 A;  2VPZ A;  2E2H A;  2A6H D;  1E18 A;  1KQG A;  2E2I A;  1G8J A;  2YU9 A;  2WAQ A;  2JIR A;  4GA6 A;  2R7Z A;  1SMY D;  1WLF A;  1YNN D;  2AE0 X;  2VPX A;  1CZ4 A;  2JA5 A;  2PIC A;  1YNJ D;  2YUJ A;  4GA5 A;  5FTJ A;  1TMO A;  1E5V A;  1PT0 A;  3HU1 A;  4QIW A;  3CZB A;  1AA6 A;  2B63 A;  2PJH B;  2A68 D;  1R7R A;  1H0H A;  3HU2 A;  3H0G A;  2PJJ A;  4DMR A;  1IW7 D;  1TWC A;  1TWH A;  2VPW A;  3QWZ A;  3IR6 A;  1OGY A;  2JIO A;  1ZYR D;  3GTO A;  2WB1 A;  2V3V A;  2R92 A;  2E7Z A;  4AZD A;  2JA6 A;  1E61 A;  1FDO A;  1VC3 B;  3QQ7 A;  4CRZ A;  5B6C A;  4D7Z B;  3GTG A;  2NVX A;  2JIM A;  1WCM A;  5DYG A;  2V45 A;  2NYA A;  4AOK B;  1PQE A;  1R27 A;  1DMS A;  1SFO A;  2PMZ A;  2DMR A;  4CS0 A;  1K83 A;  2JA7 A;  2Y0S A;  1UHE A;  3TIW A;  3HU3 A;  2BE5 D;  4KO8 A;  5FTN A;  2VPY A;  1DMR A;  2C45 A;  3QC8 A;  3FKI A;  1Y1V A;  1AW8 B;  4RV0 A;  2A6E D;  4AON B;  3GTL A;  2GAE A;  3ML1 A;  1CR5 A;  4AAY A;  3DMR A;  2EEO B;  1E60 A;  5C1B A;  1G8K A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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