1PYQA

Unprocessed aspartate decarboxylase mutant, with alanine inserted at position 24
Total Genus 38
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
38
sequence length
120
structure length
120
Chain Sequence
PRGSMIRTMLQGKLHRVKVTHADLHYEAGSCAIDQDFLDAAGILENEAIDIWNVTNGKRFSTYAIAAERGSRIISVNGAAAHCASVGDIVIIASFVTMPDEEARTWRPNVAYFEGDNEMK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Constraints on protein self-processing in L-aspartate-alpha-decarboxylase
pubmed doi rcsb
source organism Escherichia coli
molecule tags Lyase
molecule keywords Aspartate 1-decarboxylase
total genus 38
structure length 120
sequence length 120
chains with identical sequence B
ec nomenclature ec 4.1.1.11: Aspartate 1-decarboxylase.
pdb deposition date 2003-07-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02261 Asp_decarbox Aspartate decarboxylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.40.20 Mainly Beta Beta Barrel Barwin-like endoglucanases Barwin-like endoglucanases 1pyqA00
2IV2X 4GA5A 1SFOA 3IR6A 5T5ID 1E18A 2JIQA 3TIWA 1TWHA 2DMRA 2JIOA 1I50A 5C18A 3QQ7A 1OGYA 2NVXA 1TWAA 1TWFA 5EPPA 3CQZA 4AAYA 3HU2A 4KLNA 1UHEA 1WLFA 2C45A 4KDIA 1PQHA 1AW8B 1I3QA 1Q16A 3QQ8A 3TM7B 2Y0SA 2JA6A 1R7RA 2R7ZA 1Y1VA 2NVYA 3H0GA 1SIWA 4GA6A 4QIWA 2JIPA 1CZ5A 4DMRA 1FDOA 1PPYA 3CF2A 1G8JA 4AZDA 1Y4ZA 4AOKB 1FDIA 1UHDA 3O5AA 2EEOB 2PMZA 2E2HA 2R93A 5T5MD 3GTJA 1E5VA 1QDNA 1PYQA 3GTMA 2V45A 2E2IA 4CS0A 5FTJA 1H5NA 3DMRA 5FTLA 1S3SA 2VPYA 1KQFA 4RV0A 5C1BA 2VPWA 2R92A 1R9TA 1PQFA 2WB1A 1DMSA 1CR5A 3QC8A 1G8KA 5DYIA 3GTKA 1TWCA 1WCMA 1K83A 3HU1A 1E60A 5FTKA 1TWGA 4CRYG 1Y1WA 4KO8A 2JIMA 5DYGA 2VPXA 2JA7A 2V3VA 1PT0A 1PYUB 1E32A 1KQGA 5B6CA 2E7ZA 3GTGA 3QWZA 4C2MA 3GTLA 3GTPA 1PQEA 1Y5IA 5FTNA 2JIRA 1E61A 5FTMA 1R27A 2NAPA 1IW7D 2VUMA 2PJHB 1DMRA 1QCSA 2B63A 3HU3A 4AYBA 1TMOA 1H0HA 4KDLA 2YU9A 2WAQA 2KI8A 4KODA 4CRZA 1EU1A 3IR7A 1CZ4A 2VPZA 4D7ZB 1PT1A 3ML1A 3GTOA 3HKZA 1YLEA 3PLXB 1AA6A 4AONB 3FKIA 3IR5A 2NYAA 2JA5A 3GTQA 3OUGA 5GLFA 1VC3B
chains in the Genus database with same CATH superfamily
4JJOA 4GA5A 2IV2X 4ENGA 1SFOA 3IR6A 2PI8A 5T5ID 4FFTA 3X2NA 1E18A 2JIQA 3TIWA 1TWHA 2DMRA 2JIOA 1I50A 2A6HD 3SUMA 5C18A 3QQ7A 1OGYA 2NVXA 1TWAA 1TWFA 5EPPA 3CQZA 3X2JA 4AAYA 3HU2A 4KLNA 3X2OA 3X2KA 1UHEA 1WLFA 2C45A 2CW0D 4KDIA 1PQHA 1AW8B 1L8FA 1I3QA 1Q16A 4AVRA 3QQ8A 3TM7B 2Y0SA 3X2HA 3M3GA 2JA6A 3D30A 1R7RA 2R7ZA 1Y1VA 2NVYA 1OA7A 1SIWA 3CZBA 3H0GA 4GA6A 4QIWA 2JIPA 1OA9A 1CZ5A 2A69D 4DMRA 1FDOA 1PPYA 3CF2A 1G8JA 4AZDA 1Y4ZA 4AOKB 1FDIA 1UHDA 3X2IA 3O5AA 1BW4A 4JCWA 2EEOB 2PMZA 2E2HA 2R93A 2BE5D 2G6GA 2A6ED 2PNWA 5T5MD 3GTJA 1E5VA 1QDNA 1PYQA 3GTMA 2A68D 2V45A 3ENGA 2E2IA 4CS0A 5FTJA 1H5NA 3DMRA 3SUJA 2PICA 5FTLA 1S3SA 2VPYA 3X2GA 1KQFA 4RV0A 5C1BA 2VPWA 2R92A 3X2MA 1ZC1A 1R9TA 1PQFA 2WB1A 2ENGA 1DMSA 1CR5A 1WC2A 3QC8A 4JP6A 1G8KA 5DYIA 3GTKA 1TWCA 1WCMA 1K83A 3HU1A 1E60A 1ZYRD 1TWGA 5FTKA 3SUKA 4CRYG 1Y1WA 4KO8A 4NOHA 2JIMA 4JS7A 2VPXA 5DYGA 2V3VA 2JA7A 1PT0A 1PYUB 1E32A 3SULA 1KQGA 5B6CA 2E7ZA 3GTGA 3QWZA 4C2MA 3GTLA 2HCZX 3GTPA 1PQEA 1Y5IA 2PJJA 5FTNA 5H4UA 2JIRA 2KQAA 4ZM7A 1E61A 5FTMA 1R27A 1BW3A 2NAPA 1IW7D 3GTQA 4FERA 4L48A 1SMYD 2VUMA 2PJHB 1DMRA 1QCSA 2AE0X 2B63A 3HU3A 5GLYA 4AYBA 5GLXA 5GM9A 1TMOA 1H0HA 4FG2A 4KDLA 2GAEA 1YNND 2BH0A 2YU9A 2WAQA 2KI8A 3X2LA 4KODA 2YUJA 3X2PA 2G5DA 1EU1A 4CRZA 3IR7A 4JP7A 2O5JD 1CZ4A 2VPZA 4D7ZB 1PT1A 3ML1A 3GTOA 3HKZA 1N10A 1YLEA 3PLXB 1YNJD 4AONB 1AA6A 3FKIA 3IR5A 2NYAA 2JA5A 1HD5A 3OUGA 5GLFA 1VC3B 4FG4A
chains in the Genus database with same CATH topology
2IV2X 4GA5A 1SFOA 3IR6A 2PI8A 5T5ID 1E18A 2JIQA 3TIWA 1TWHA 2DMRA 2JIOA 1I50A 2A6HD 5C18A 3QQ7A 1OGYA 2NVXA 1TWAA 1TWFA 5EPPA 3CQZA 4AAYA 3HU2A 4KLNA 1UHEA 1WLFA 2C45A 2CW0D 4KDIA 1PQHA 1AW8B 1I3QA 1Q16A 3QQ8A 3TM7B 2Y0SA 2JA6A 1R7RA 2R7ZA 1Y1VA 2NVYA 3H0GA 1SIWA 3CZBA 4GA6A 4QIWA 2JIPA 1CZ5A 2A69D 4DMRA 1FDOA 1PPYA 3CF2A 1G8JA 4AZDA 1Y4ZA 4AOKB 1FDIA 1UHDA 3O5AA 2EEOB 2PMZA 2E2HA 2R93A 2BE5D 2G6GA 2A6ED 2PNWA 5T5MD 3GTJA 1E5VA 1QDNA 1PYQA 3GTMA 2A68D 2V45A 2E2IA 4CS0A 5FTJA 1H5NA 3DMRA 2PICA 5FTLA 1S3SA 2VPYA 1KQFA 4RV0A 5C1BA 2VPWA 2R92A 1R9TA 1ZC1A 1PQFA 2WB1A 1DMSA 1CR5A 3QC8A 1G8KA 5DYIA 3GTKA 1TWCA 1WCMA 1K83A 3HU1A 1E60A 1ZYRD 1TWGA 5FTKA 4CRYG 1Y1WA 4KO8A 4NOHA 2JIMA 5DYGA 2VPXA 2JA7A 2V3VA 1PT0A 1PYUB 1E32A 1KQGA 5B6CA 2E7ZA 3GTGA 3QWZA 4C2MA 3GTLA 3GTPA 1PQEA 1Y5IA 2PJJA 5FTNA 2JIRA 1E61A 5FTMA 1R27A 2NAPA 1IW7D 1SMYD 2VUMA 2PJHB 1DMRA 1QCSA 2AE0X 2B63A 3HU3A 4AYBA 1TMOA 1H0HA 4KDLA 2GAEA 1YNND 2YU9A 2WAQA 2KI8A 4KODA 2YUJA 2G5DA 1EU1A 4CRZA 3IR7A 2O5JD 1CZ4A 2VPZA 4D7ZB 1PT1A 3ML1A 3GTOA 3HKZA 1YLEA 3PLXB 1YNJD 4AONB 1AA6A 3FKIA 3IR5A 2NYAA 2JA5A 3GTQA 3OUGA 5GLFA 1VC3B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2IV2 X;  4GA5 A;  1SFO A;  3IR6 A;  5T5I D;  1E18 A;  2JIQ A;  3TIW A;  1TWH A;  2DMR A;  2JIO A;  1I50 A;  5C18 A;  3QQ7 A;  1OGY A;  2NVX A;  1TWA A;  1TWF A;  5EPP A;  3CQZ A;  4AAY A;  3HU2 A;  4KLN A;  1UHE A;  1WLF A;  2C45 A;  4KDI A;  1PQH A;  1AW8 B;  1I3Q A;  1Q16 A;  3QQ8 A;  3TM7 B;  2Y0S A;  2JA6 A;  1R7R A;  2R7Z A;  1Y1V A;  2NVY A;  3H0G A;  1SIW A;  4GA6 A;  4QIW A;  2JIP A;  1CZ5 A;  4DMR A;  1FDO A;  1PPY A;  3CF2 A;  1G8J A;  4AZD A;  1Y4Z A;  4AOK B;  1FDI A;  1UHD A;  3O5A A;  2EEO B;  2PMZ A;  2E2H A;  2R93 A;  5T5M D;  3GTJ A;  1E5V A;  1QDN A;  1PYQ A;  3GTM A;  2V45 A;  2E2I A;  4CS0 A;  5FTJ A;  1H5N A;  3DMR A;  5FTL A;  1S3S A;  2VPY A;  1KQF A;  4RV0 A;  5C1B A;  2VPW A;  2R92 A;  1R9T A;  1PQF A;  2WB1 A;  1DMS A;  1CR5 A;  3QC8 A;  1G8K A;  5DYI A;  3GTK A;  1TWC A;  1WCM A;  1K83 A;  3HU1 A;  1E60 A;  5FTK A;  1TWG A;  4CRY G;  1Y1W A;  4KO8 A;  2JIM A;  5DYG A;  2VPX A;  2JA7 A;  2V3V A;  1PT0 A;  1PYU B;  1E32 A;  1KQG A;  5B6C A;  2E7Z A;  3GTG A;  3QWZ A;  4C2M A;  3GTL A;  3GTP A;  1PQE A;  1Y5I A;  5FTN A;  2JIR A;  1E61 A;  5FTM A;  1R27 A;  2NAP A;  1IW7 D;  2VUM A;  2PJH B;  1DMR A;  1QCS A;  2B63 A;  3HU3 A;  4AYB A;  1TMO A;  1H0H A;  4KDL A;  2YU9 A;  2WAQ A;  2KI8 A;  4KOD A;  4CRZ A;  1EU1 A;  3IR7 A;  1CZ4 A;  2VPZ A;  4D7Z B;  1PT1 A;  3ML1 A;  3GTO A;  3HKZ A;  1YLE A;  3PLX B;  1AA6 A;  4AON B;  3FKI A;  3IR5 A;  2NYA A;  2JA5 A;  3GTQ A;  3OUG A;  5GLF A;  1VC3 B; 
#chains in the Genus database with same CATH topology
 4JJO A;  4GA5 A;  2IV2 X;  4ENG A;  1SFO A;  3IR6 A;  2PI8 A;  5T5I D;  4FFT A;  3X2N A;  1E18 A;  2JIQ A;  3TIW A;  1TWH A;  2DMR A;  2JIO A;  1I50 A;  2A6H D;  3SUM A;  5C18 A;  3QQ7 A;  1OGY A;  2NVX A;  1TWA A;  1TWF A;  5EPP A;  3CQZ A;  3X2J A;  4AAY A;  3HU2 A;  4KLN A;  3X2O A;  3X2K A;  1UHE A;  1WLF A;  2C45 A;  2CW0 D;  4KDI A;  1PQH A;  1AW8 B;  1L8F A;  1I3Q A;  1Q16 A;  4AVR A;  3QQ8 A;  3TM7 B;  2Y0S A;  3X2H A;  3M3G A;  2JA6 A;  3D30 A;  1R7R A;  2R7Z A;  1Y1V A;  2NVY A;  1OA7 A;  1SIW A;  3CZB A;  3H0G A;  4GA6 A;  4QIW A;  2JIP A;  1OA9 A;  1CZ5 A;  2A69 D;  4DMR A;  1FDO A;  1PPY A;  3CF2 A;  1G8J A;  4AZD A;  1Y4Z A;  4AOK B;  1FDI A;  1UHD A;  3X2I A;  3O5A A;  1BW4 A;  4JCW A;  2EEO B;  2PMZ A;  2E2H A;  2R93 A;  2BE5 D;  2G6G A;  2A6E D;  2PNW A;  5T5M D;  3GTJ A;  1E5V A;  1QDN A;  1PYQ A;  3GTM A;  2A68 D;  2V45 A;  3ENG A;  2E2I A;  4CS0 A;  5FTJ A;  1H5N A;  3DMR A;  3SUJ A;  2PIC A;  5FTL A;  1S3S A;  2VPY A;  3X2G A;  1KQF A;  4RV0 A;  5C1B A;  2VPW A;  2R92 A;  3X2M A;  1ZC1 A;  1R9T A;  1PQF A;  2WB1 A;  2ENG A;  1DMS A;  1CR5 A;  1WC2 A;  3QC8 A;  4JP6 A;  1G8K A;  5DYI A;  3GTK A;  1TWC A;  1WCM A;  1K83 A;  3HU1 A;  1E60 A;  1ZYR D;  1TWG A;  5FTK A;  3SUK A;  4CRY G;  1Y1W A;  4KO8 A;  4NOH A;  2JIM A;  4JS7 A;  2VPX A;  5DYG A;  2V3V A;  2JA7 A;  1PT0 A;  1PYU B;  1E32 A;  3SUL A;  1KQG A;  5B6C A;  2E7Z A;  3GTG A;  3QWZ A;  4C2M A;  3GTL A;  2HCZ X;  3GTP A;  1PQE A;  1Y5I A;  2PJJ A;  5FTN A;  5H4U A;  2JIR A;  2KQA A;  4ZM7 A;  1E61 A;  5FTM A;  1R27 A;  1BW3 A;  2NAP A;  1IW7 D;  3GTQ A;  4FER A;  4L48 A;  1SMY D;  2VUM A;  2PJH B;  1DMR A;  1QCS A;  2AE0 X;  2B63 A;  3HU3 A;  5GLY A;  4AYB A;  5GLX A;  5GM9 A;  1TMO A;  1H0H A;  4FG2 A;  4KDL A;  2GAE A;  1YNN D;  2BH0 A;  2YU9 A;  2WAQ A;  2KI8 A;  3X2L A;  4KOD A;  2YUJ A;  3X2P A;  2G5D A;  1EU1 A;  4CRZ A;  3IR7 A;  4JP7 A;  2O5J D;  1CZ4 A;  2VPZ A;  4D7Z B;  1PT1 A;  3ML1 A;  3GTO A;  3HKZ A;  1N10 A;  1YLE A;  3PLX B;  1YNJ D;  4AON B;  1AA6 A;  3FKI A;  3IR5 A;  2NYA A;  2JA5 A;  1HD5 A;  3OUG A;  5GLF A;  1VC3 B;  4FG4 A; 
#chains in the Genus database with same CATH homology
 2IV2 X;  4GA5 A;  1SFO A;  3IR6 A;  2PI8 A;  5T5I D;  1E18 A;  2JIQ A;  3TIW A;  1TWH A;  2DMR A;  2JIO A;  1I50 A;  2A6H D;  5C18 A;  3QQ7 A;  1OGY A;  2NVX A;  1TWA A;  1TWF A;  5EPP A;  3CQZ A;  4AAY A;  3HU2 A;  4KLN A;  1UHE A;  1WLF A;  2C45 A;  2CW0 D;  4KDI A;  1PQH A;  1AW8 B;  1I3Q A;  1Q16 A;  3QQ8 A;  3TM7 B;  2Y0S A;  2JA6 A;  1R7R A;  2R7Z A;  1Y1V A;  2NVY A;  3H0G A;  1SIW A;  3CZB A;  4GA6 A;  4QIW A;  2JIP A;  1CZ5 A;  2A69 D;  4DMR A;  1FDO A;  1PPY A;  3CF2 A;  1G8J A;  4AZD A;  1Y4Z A;  4AOK B;  1FDI A;  1UHD A;  3O5A A;  2EEO B;  2PMZ A;  2E2H A;  2R93 A;  2BE5 D;  2G6G A;  2A6E D;  2PNW A;  5T5M D;  3GTJ A;  1E5V A;  1QDN A;  1PYQ A;  3GTM A;  2A68 D;  2V45 A;  2E2I A;  4CS0 A;  5FTJ A;  1H5N A;  3DMR A;  2PIC A;  5FTL A;  1S3S A;  2VPY A;  1KQF A;  4RV0 A;  5C1B A;  2VPW A;  2R92 A;  1R9T A;  1ZC1 A;  1PQF A;  2WB1 A;  1DMS A;  1CR5 A;  3QC8 A;  1G8K A;  5DYI A;  3GTK A;  1TWC A;  1WCM A;  1K83 A;  3HU1 A;  1E60 A;  1ZYR D;  1TWG A;  5FTK A;  4CRY G;  1Y1W A;  4KO8 A;  4NOH A;  2JIM A;  5DYG A;  2VPX A;  2JA7 A;  2V3V A;  1PT0 A;  1PYU B;  1E32 A;  1KQG A;  5B6C A;  2E7Z A;  3GTG A;  3QWZ A;  4C2M A;  3GTL A;  3GTP A;  1PQE A;  1Y5I A;  2PJJ A;  5FTN A;  2JIR A;  1E61 A;  5FTM A;  1R27 A;  2NAP A;  1IW7 D;  1SMY D;  2VUM A;  2PJH B;  1DMR A;  1QCS A;  2AE0 X;  2B63 A;  3HU3 A;  4AYB A;  1TMO A;  1H0H A;  4KDL A;  2GAE A;  1YNN D;  2YU9 A;  2WAQ A;  2KI8 A;  4KOD A;  2YUJ A;  2G5D A;  1EU1 A;  4CRZ A;  3IR7 A;  2O5J D;  1CZ4 A;  2VPZ A;  4D7Z B;  1PT1 A;  3ML1 A;  3GTO A;  3HKZ A;  1YLE A;  3PLX B;  1YNJ D;  4AON B;  1AA6 A;  3FKI A;  3IR5 A;  2NYA A;  2JA5 A;  3GTQ A;  3OUG A;  5GLF A;  1VC3 B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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